Displaying drugs 101 - 125 of 191 in total
Mitoxantrone
An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … MİTOXANTRONE BAXTER 20 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... MİTOXANTRONE-KOÇAK 20 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... MİTOXANTRON EBEWE 10 MG/5 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Matched Products: … MİTOXANTRONE BAXTER 20 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... MİTOXANTRONE-KOÇAK 20 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... MİTOXANTRON EBEWE 10 MG/5 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Fomivirsen
Fomivirsen is a antisense 21 mer phosphorothioate oligonucleotide. It is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised patients, including those with AIDS. As a complementary nucleotide to the messenger RNA of the major immediate-early region proteins of human cytomegalovirus, it disrupts the...
Approved
Investigational
Withdrawn
Matched Description: … As a complementary nucleotide to the messenger RNA of the major immediate-early region proteins of human ... drug to be approved by the Food and Drug Administration (FDA). ... _Isis Pharmaceuticals_ and subsequently licensed to _Novartis_ [A31990]. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Tozinameran
The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of four advanced mRNA-based vaccines developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002,L15007,L36025] Comirnaty is a nucleoside modified mRNA (modRNA) vaccine encoding an optimized full-length version of the severe acute respiratory syndrome coronavirus 2...
Approved
Investigational
Matched Description: … [L15027] On December 11, 2020, the FDA issued an Emergency Use Authorization (EUA) based on 95% efficacy ... optimized full-length version of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein ... The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of …
Matched Mixtures name: … Comirnaty Original/omicron Ba.1 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Mixtures name: … Comirnaty Original/omicron Ba.1 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Andusomeran
Andusomeran is a COVID-19 mRNA vaccine developed for use during the 2023-2024 season.[L40074,L48832,L48837] It is similar to previous mRNA vaccines developed by Moderna (e.g. elasomeran, imelasomeran), but is designed to be effective against the Omicron XBB.1.5 subvariant.
Approved
Galactose
Galactose has been used in trials studying the treatment and diagnosis of Hepatitis C, Hepatic Cancer, Wilsons Disease, Diabetic Macular Oedema, and Focal Segmental Glomerulosclerosis, among others. There are even proposals for its use in accelerating senescence in mice, rats, and Drosophila, for its association with ovarian cancer, or even...
Approved
Investigational
Matched Description: … Regardless, although it is predominantly used as a pathway to generate glucose fuel for the human body ... Galactose has been used in trials studying the treatment and diagnosis of Hepatitis C, Hepatic Cancer ... , Wilsons Disease, Diabetic Macular Oedema, and Focal Segmental Glomerulosclerosis, among others. …
Teplizumab
Teplizumab (teplizumab-mzwv) is a humanized IgG1 kappa CD3-directed monoclonal antibody used to delay the onset of type 1 diabetes (T1D).[A241480,A241045,A241475,L44091] T1D is an autoimmune condition in which T cell-mediated destruction of pancreatic β cells leads to loss of insulin production, impaired glycemic control, and reliance on exogenous insulin. Anti-CD3 therapy...
Approved
Investigational
Matched Description: … 1 diabetes. ... 1 diabetes (T1D). ... [L44091] Fc-receptors can bind to the "tail-end" anti-CD3 antibodies in an antigen-non-specific manner …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Inotuzumab ozogamicin
Inotuzumab ozogamicin is an antibody-drug conjugate using linker and cytotoxic drug technology similar to that developed for the ground-breaking treatment Mylotarg (DB00056), which was approved by the US FDA in 2000 for the treatment of acute myeloid leukaemia. Inotuzumab ozogamicin consists of a recombinant humanised IgG4 kappa CD22-targeting monoclonal antibody...
Approved
Investigational
Matched Description: … Inotuzumab ozogamicin is an antibody-drug conjugate using linker and cytotoxic drug technology similar ... Developed by Pfizer and UCB, inotuzumab ozogamicin was granted approval by EU in June 2017 followed by ... ALL is a rapidly progressing cancer of the bone marrow that is associated with high mortality rates and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … BESPONSA 1 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … BESPONSA 1 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET …
Besilesomab
Besilesomab is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m for determining the location of inflammation/infection in peripheral bone in adults with suspected osteomyelitis [FDA Label]. Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and use in various European countries like...
Approved
Matched Description: … Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and ... various European countries like Italy, France, Germany, Spain, Portugal, Norway, Sweden, the Netherlands, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Hydroxychloroquine
Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in...
Approved
Matched Synonyms: … 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline ... 7-chloro-4-(4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino)quinoline ... 7-chloro-4-[4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino]quinoline …
Matched Iupac: … 2-({4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino)ethan-1-ol …
Matched Description: … [L14312]** Hydroxychloroquine was granted FDA approval on 18 April 1955. ... Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. ... the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Iupac: … 2-({4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino)ethan-1-ol …
Matched Description: … [L14312]** Hydroxychloroquine was granted FDA approval on 18 April 1955. ... Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. ... the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Montelukast
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Synonyms: … 1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl] ... (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl …
Matched Iupac: … 2-[1-({[(1R)-1-{3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl …
Matched Description: … has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... L6325,L6328,L6331] the drug still sees extensive use worldwide via millions of prescriptions annually and …
Matched Salts cas: … 151767-02-1 …
Matched Mixtures name: … BREATHEZY - L ... GLEMONT L® TABLETAS RECUBIERTAS …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … 2-[1-({[(1R)-1-{3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl …
Matched Description: … has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... L6325,L6328,L6331] the drug still sees extensive use worldwide via millions of prescriptions annually and …
Matched Salts cas: … 151767-02-1 …
Matched Mixtures name: … BREATHEZY - L ... GLEMONT L® TABLETAS RECUBIERTAS …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Pirtobrutinib
Pirtobrutinib is a small molecule and a highly selective non-covalent inhibitor of Bruton’s tyrosine kinase (BTK). Its high selectivity has been associated with lower discontinuation rates due to adverse events and a lower incidence of atrial fibrillation. Unlike BTK covalent inhibitors, such as ibrutinib, that bind to the cysteine 481...
Approved
Investigational
Matched Synonyms: … -trifluoro-1-methylethyl)- ... (s)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1h-pyrazole ... 1h-pyrazole-4-carboxamide, 5-amino-3-(4-(((5-fluoro-2-methoxybenzoyl)amino)methyl)phenyl)-1-((1s)-2,2,2 …
Matched Iupac: … 5-amino-3-(4-{[(5-fluoro-2-methoxyphenyl)formamido]methyl}phenyl)-1-[(2S)-1,1,1-trifluoropropan-2-yl] …
Matched Description: … Pirtobrutinib is a small molecule and a highly selective non-covalent inhibitor of Bruton’s tyrosine ... Its high selectivity has been associated with lower discontinuation rates due to adverse events and a …
Matched Categories: … Protein Kinase Inhibitors ... Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 5-amino-3-(4-{[(5-fluoro-2-methoxyphenyl)formamido]methyl}phenyl)-1-[(2S)-1,1,1-trifluoropropan-2-yl] …
Matched Description: … Pirtobrutinib is a small molecule and a highly selective non-covalent inhibitor of Bruton’s tyrosine ... Its high selectivity has been associated with lower discontinuation rates due to adverse events and a …
Matched Categories: … Protein Kinase Inhibitors ... Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents …
Imlifidase
Chronic kidney disease (CKD) is a progressive and irreversible disease that represents a significant burden for both the individual and healthcare system at large. Currently available treatments for end-stage renal disease are limited to dialysis and renal transplantation, with the former associated with significant costs and lower quality of life.[A225836,A225916]...
Approved
Investigational
Matched Description: … [A225836,A225916]
Patients who have developed human leukocyte antigen (HLA) sensitization from prior ... such as CDC and ADCC by cleaving the heavy chains of human immunoglobulin G (IgG) antibodies. ... burden for both the individual and healthcare system at large. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Verpasep caltespen
Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a...
Investigational
Matched Synonyms: … Heat-shock protein HSP 65 (Mycobacterium BCG) fusion protein with transcription factor E7 (human papillomavirus ... Recombinant fusion protein of Mycobacterium bovis BCG Hsp65 and HPV16 E7 ... 16) …
Matched Description: … _Mycobacterium bovis_, and the human papilloma viral (HPV) protein E7. ... E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen ... Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from …
Matched Description: … _Mycobacterium bovis_, and the human papilloma viral (HPV) protein E7. ... E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen ... Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from …
Axalimogene filolisbac
Axalimogene filolisbac is under investigation in clinical trial NCT02853604 (Study of ADXS11-001 in Subjects With High Risk Locally Advanced Cervical Cancer).
Investigational
Matched Synonyms: … Live, attenuated listeria monocytogenes bacteria, expressing human papilloma virus type 16-e7 tumor antigen …
Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine
Through analysis of potential immunogenic targets of the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and a polyprotein protease. Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and with the described approach, the vaccine uses these...
Investigational
Matched Synonyms: … artificial antigen -Pathogen-specific vaccine …
Matched Name: … Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine …
Matched Description: … , modify artificial antigen presenting cells (aAPC), and activate T-cells. ... Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, ... As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials …
Matched Name: … Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine …
Matched Description: … , modify artificial antigen presenting cells (aAPC), and activate T-cells. ... Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, ... As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials …
Asunercept
Asunercept is under investigation in clinical trial NCT02853565 (A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme).
Investigational
Matched Synonyms: … FAS ANTIGEN (HUMAN EXTRACELLULAR DOMAIN FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Timolumab
Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … protein-1 (VAP-1) ... recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion …
Matched Description: … vascular adhesion protein-1 (VAP-1). ... Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … vascular adhesion protein-1 (VAP-1). ... Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vitespen
Investigational
Matched Synonyms: … Endoplasmin (human tumor rejection antigen 1) ... Heat shock protein-peptide complex-96 vaccine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Gresonitamab
Investigational
Matched Synonyms: … ANTI-(HUMAN CD3 ANTIGEN .EPSILON. ... FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ... IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN CLAUDIN 18.2) (HUMAN MONOCLONAL HWZV_KLA_L SINGLE-CHAIN VARIABLE …
Baloramotide
Investigational
Matched Synonyms: … Glycyl-l-prolyl-human cancer/testis antigen 1 (autoimmunogenic cancer/testis antigen ny-eso-1, l antigen ... Recombinant NY-ESO-1 protein ... Cancer testis antigen ny-eso-1 (recombinant human) …
Vepsitamab
Investigational
Matched Synonyms: … ANTI-(HUMAN CD3 ANTIGEN .EPSILON. ... FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ... IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN MUCIN 17) (HUMAN MONOCLONAL MUC17_CD3_ALT2 SINGLE-CHAIN VARIABLE …
Xaluritamig
Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
Investigational
Matched Synonyms: … epithelial antigen of the prostate 1, STEAP1 metalloreductase) and anti-[Homo sapiens CD3, bispecific ... anti-(human CD3 antigen) (human-Mus muscul ... clone 2F3.013 N67Q γ1-chain) fusion protein with peptide linker (GGGGS)2 fusion protein with immunoglobulin …
Matched Description: … Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman ... primate STEAP1 and CD3. …
Matched Description: … Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman ... primate STEAP1 and CD3. …
Ocaratuzumab
Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.
Investigational
Matched Synonyms: … surface antigen Leu-16, membrane-spanning 4-domains subfamily A member 1)) ... Immunoglobulin G1, anti-(human B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1, Bp35, leukocyte …
Matched Description: … It is being investigated for cancers and autoimmune disorders. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It is being investigated for cancers and autoimmune disorders. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Acimtamig
Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct.
Investigational
Matched Synonyms: … linker (GGS)3 fusion protein with immunoglobulin anti-(human CD30 antigen) (human-Mus musculus single-chain ... Immunoglobulin, anti-(human FcγRIIIa receptor) (human heavy chain V-D-J region) fusion protein with peptide ... tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct …
Matched Description: … Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Seviprotimut-L
Seviprotimut-L is under investigation in clinical trial NCT01546571 (Study of a Melanoma Vaccine in Stage Iib, Iic, and III Melanoma Patients).
Investigational
Matched Synonyms: … Human polyvalent shedded antigen vaccine ... Seviprotimut L ... Seviprotimut-L …
Matched Name: … Seviprotimut-L …
Matched Description: … Iib, Iic, and III Melanoma Patients). ... Seviprotimut-L is under investigation in clinical trial NCT01546571 (Study of a Melanoma Vaccine in Stage …
Matched Name: … Seviprotimut-L …
Matched Description: … Iib, Iic, and III Melanoma Patients). ... Seviprotimut-L is under investigation in clinical trial NCT01546571 (Study of a Melanoma Vaccine in Stage …
Displaying drugs 101 - 125 of 191 in total