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Displaying drugs 101 - 125 of 8023 in total

Sertaconazole

Sertaconazole nitrate is an antifungal medication of the imidazole class. It is available in topical formulations for the treatment of skin infections such as athlete's foot.
Approved
Investigational
Matched Description: … Sertaconazole nitrate is an antifungal medication of the imidazole class. ... It is available in topical formulations for the treatment of skin infections such as athlete's foot. …
Matched Categories: … combinations of imidazole derivatives …

Ticarcillin

An antibiotic derived from penicillin similar to carbenicillin in action.
Approved
Investigational
Vet approved
Matched Categories: … combinations of penicillins …

Isoconazole

Isoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.
Approved
Matched Description: … Isoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of …
Matched Categories: … combinations of imidazole derivatives …

Dexpanthenol

Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that...
Approved
Matched Description: … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and ... Dermatological effects of the topical use of dexpanthenol include increased fibroblast proliferation ... an essential component of a normally functioning epithelium. …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Pafolacianine

Pafolacianine, or OTL38, is a folate analogue conjugated with a fluorescent dye that absorbs light in the near-infrared (NIR) spectrum within a range of 760 nm to 785 nm, with a peak absorption of 776 nm. It emits fluorescence within a range of 790 nm to 815 nm with a...
Approved
Investigational
Matched Description: … It emits fluorescence within a range of 790 nm to 815 nm with a peak emission of 796 nm. ... for better imaging and detection of tumours. ... 760 nm to 785 nm, with a peak absorption of 776 nm. …
Matched Categories: … Diagnostic Uses of Chemicals …

Azlocillin

Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin.
Approved
Matched Categories: … combinations of penicillins …

Oxacillin

An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Categories: … combinations of penicillins …

Diazoxide

Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Description: … Diazoxide is usually well tolerated, and some of its more common side effects include fluid retention ... [A190372] Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability ... In September 2015, the FDA issued a safety alert regarding post-marketing reports of pulmonary hypertension …
Matched Categories: … combinations of sulfonamides …

Tibolone

Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha . Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Description: … and the treatment of post-menopausal symptoms [L1720]. ... In June 2006, Organon Pharmaceuticals announced the receipt of a Not Approvable Letter from the U.S. ... approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the development of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Gadoteric acid

Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Description: … [A263131] It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic ... [A263136] Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and ... its macrocyclic structure, and thus has a more favorable safety profile due to a decreased tendency of …
Matched Categories: … Diagnostic Uses of Chemicals …

Furosemide

Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... [A182495] The use of furosemide is particularly beneficial in clinical settings that require a drug with …
Matched Categories: … combinations of sulfonamides ... Increased Diuresis at Loop of Henle …

Diphenoxylate

A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medication is classified as a Schedule V under the Controlled Substances Act...
Approved
Illicit
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Daratumumab

Daratumumab is an immunoglobulin G1 kappa monoclonal antibody developed by Janssen and Genmab. It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind. Daratumumab was granted FDA approval on 16 November 2015. It is approved for...
Approved
Matched Description: … the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of ... [L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and …
Matched Categories: … CD38 (Clusters of Differentiation 38) inhibitors …

Gadofosveset trisodium

Gadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels. The agent allows for the vascular system to be imaged more clearly by the MRA. In this way, gadofosveset trisodium is used to help diagnose certain disorders of the...
Approved
Matched Description: … intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of ... In this way, gadofosveset trisodium is used to help diagnose certain disorders of the heart and blood …
Matched Categories: … Diagnostic Uses of Chemicals …

Bedaquiline

Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Description: … [L48506] Although the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key ... Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. ... fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Moxetumomab pasudotox

CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia, hairy cell leukemia, acute lymphocytic leukemiathe and Burkitt's lymphoma. The predecessor of Moxetumab pasudotox (MxP), named BL22, was first created based on the antibody RFB4 which specifically binds to CD22. This antibody was used to...
Approved
Investigational
Matched Description: … [A38864] MxP appears as an improved form of BL22 by the mutation of the Fv region and the antibody ... The predecessor of Moxetumab pasudotox (MxP), named BL22, was first created based on the antibody RFB4 ... was developed by Astra Zeneca and FDA approved on September 13, 2018, after being granted the status of …
Matched Categories: … CD22 (Clusters of Differentiation 22) inhibitors …

Gadodiamide

Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.[A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents. Approved by the FDA...
Approved
Investigational
Matched Description: … agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of ... [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than …
Matched Categories: … Diagnostic Uses of Chemicals …

Gadopentetic acid

A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Approved
Matched Description: … A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic …
Matched Categories: … Diagnostic Uses of Chemicals …

Iodipamide

Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Sodium chloride

Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed...
Approved
Vet approved
Matched Description: … It is listed on the World Health Organization Model List of Essential Medicines. ... table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of ... Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular …
Matched Mixtures name: … SOLUTION OF DEXTROSE 5 % IN NORMAL SALINE 0.9 % ... SOLUTION OF DEXTROSE 10 % IN NORMAL SALINE 0.9 % …
Matched Products: … Of Nacl .9% ... Certified Nas Phys.soln Of Nacl .9% W/V B.P. …

Nialamide

Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Bazedoxifene

Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. It is approved in the...
Approved
Investigational
Matched Description: … their takeover of Wyeth Pharmaceuticals. ... prevention (not treatment) of postmenopausal osteoporosis. ... generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Methazolamide

A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Approved
Matched Description: … A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma. …
Matched Categories: … combinations of sulfonamides …

Iopamidol

Iopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Clotrimazole

This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other ... widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as well ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Categories: … combinations of imidazole derivatives …
Matched Products: … Fortinia OF …
Displaying drugs 101 - 125 of 8023 in total