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Displaying drugs 101 - 125 of 7416 in total
Flutemetamol (18F) is a PET scanning radiopharmaceutical containing the radionuclide fluorine-18. It is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) or other causes of cognitive decline.
Approved
Investigational
Matched Description: … It is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic ... patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) or other causes of
Matched Categories: … Diagnostic Uses of Chemicals …
Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Description: … ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of
Matched Categories: … Diagnostic Uses of Chemicals …
Metrizoic acid is a molecule used as a contrast medium. It present a higher risk of allergic reactions due to its high osmolality. Its approval has been discontinued by the FDA. One study in 1976 demonstrated that metrizoic acid, when used for cardiac angiography, was well tolerated. A total of...
Approved
Matched Description: … Seven cases of ventricular fibrillation, and 5 of significant bradycardia/asystole, were associated with ... It present a higher risk of allergic reactions due to its high osmolality. ... With two exceptions, all complications occurred during injection of the right coronary artery. …
Matched Categories: … Diagnostic Uses of Chemicals …
Quinupramine has been approved in France under the brand name Kinupril, as an antidepressant .
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
Approved
Matched Description: … Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed …
Matched Categories: … combinations of penicillins …
A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Approved
Investigational
Matched Description: … was previously available internationally, however in most markets it has been phased out in favour of
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Description: … demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of
Matched Categories: … combinations of imidazole derivatives ... Metabolic Side Effects of Drugs and Substances …
A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Approved
Matched Description: … It also may be used for treatment of leprosy. ... (From Smith and Reynard, Textbook of Pharmacology, 1992, p868) …
Matched Categories: … Drugs for Treatment of Tuberculosis …
Chloroprocaine hydrochloride is a local anesthetic given by injection during surgical procedures and labor and delivery. Chloroprocaine, like other local anesthetics, blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse and...
Approved
Matched Description: … the nerve impulse and by reducing the rate of rise of the action potential. ... Chloroprocaine, like other local anesthetics, blocks the generation and the conduction of nerve impulses ... presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of
Matched Categories: … Esters of Aminobenzoic Acid …
Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
Approved
Matched Categories: … combinations of sulfonamides …
Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational
Matched Description: … The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that …
Matched Categories: … Diagnostic Uses of Chemicals …
Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … class of DAAs [A19593]. ... The barrier for develoment of resistance to NS5A inhibitors is lower than that of NS5B inhibitors, another ... Lack of significant side effects and short duration of therapy is a considerable advantage over older …
Matched Categories: … Antivirals for treatment of HCV infections …
Dibenzepin is approved for use in Europe.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Gadobenic acid (in the form of gadobenate dimeglumine) is an MRI contrast agent used primarily for MR imaging of the liver. It can also be used for visualizing the CNS and heart. In contrast to conventional extracellular fluid contrast agents, gadobenate dimeglumine is characterized by a weak and transient binding...
Approved
Investigational
Matched Description: … imaging of the liver. ... increased signal intensity over that of other agents. ... Gadobenic acid (in the form of gadobenate dimeglumine) is an MRI contrast agent used primarily for MR …
Matched Categories: … Diagnostic Uses of Chemicals …
Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy. The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects.
Approved
Matched Description: … The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for ... polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of
Matched Categories: … combinations of penicillins …
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Description: … the appearance of wrinkles and aging-related skin imperfections. ... [A230133] Several preparations of hyaluronic acid have been approved by the FDA and are available in ... A popular use of hyaluronic acid in recent years is cosmetic injection due to its ability to minimize …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.
Approved
Matched Description: … It is typically used in the management of asthma, cardiac dyspnea, and bronchitis. …
Matched Categories: … combinations of xanthines …
A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage. The FDA granted marketing approval for the orphan...
Approved
Investigational
Matched Description: … Each tube of Valchlor contains 0.016% of mechlorethamine which is equivalent to 0.02% mechlorethamine ... approval for the orphan drug Valchlor (mechlorethamine) gel on August 23, 2013 for the topical treatment of
Matched Categories: … Weapons of Mass Destruction …
Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in...
Approved
Matched Description: … and high level of clearance from the body [FDA label]. ... Therapeutic advantages of barium sulfate in diagnostic procedures include both its low water solubility ... Barium sulfate is ingested by mouth or administered rectally and combined with granules of effervescent …
Matched Categories: … Diagnostic Uses of Chemicals …
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Approved
Investigational
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Matched Description: … Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality. …
Matched Categories: … Diagnostic Uses of Chemicals …
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Description: … An alkaloid ester extracted from the leaves of plants including coca. ... its reinforcing effects is thought to involve inhibition of dopamine uptake. ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Matched Categories: … Esters of Benzoic Acid ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
Approved
Vet approved
Matched Description: … A thiazide diuretic with properties similar to those of hydrochlorothiazide. …
Matched Categories: … combinations of sulfonamides …
Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … Although its exact mechanism of action is unknown, it is postulated to prevent hyperphosphorylation of ... Lack of significant side effects and short duration of therapy is a considerable advantage over older ... reduced liver-related damage, improved quality of life, reduced incidence of Hepatocellular Carcinoma …
Matched Categories: … Antivirals for treatment of HCV infections …
An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Approved
Investigational
Matched Description: … combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Displaying drugs 101 - 125 of 7416 in total