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Displaying drugs 201 - 225 of 8023 in total

Fentanyl

Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone. Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Description: … [L6748] Opioid overdoses kill an average of 11 Canadians daily. ... [A179542] Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or ... [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Vilazodone

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Lynestrenol

Lynestrenol is a progestin and prodrug of norethisterone.
Approved
Investigational
Matched Description: … Lynestrenol is a progestin and prodrug of [norethisterone]. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Ketoconazole

Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Description: … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... [FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol ... , thereby increasing membrane fluidity and preventing growth of the fungus. …
Matched Categories: … combinations of imidazole derivatives ... Metabolic Side Effects of Drugs and Substances …

Ethambutol

Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Description: … [A229048] It was developed out of a need for therapies active against isoniazid resistant strains of ... indicated alongside medications such as [isoniazid], [rifampin], and [pyrazinamide] in the treatment of …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Valdecoxib

Valdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Approved
Investigational
Withdrawn
Matched Description: … ., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke …
Matched Categories: … combinations of sulfonamides …

Flupentixol

Flupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid. Flupentixol is an antagonist of...
Approved
Investigational
Withdrawn
Matched Description: … signs of anxiety. ... Flupentixol is an antipsychotic drug of the thioxanthene group. ... by esterification of cis(Z)‐flupentixol with decanoic acid. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Almotriptan

Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Description: … Almotriptan is a triptan drug for the treatment of migraine headaches. ... Almotriptan is in a class of medications called selective serotonin receptor agonists. ... certain natural substances that cause pain, nausea, and other symptoms of migraine. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Norgestimate

Norgestimate was first described in the literature in 1977. It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. It is commonly formulated with ethinylestradiol as a combined oral contraceptive that can also be used to treat moderate acne...
Approved
Investigational
Matched Description: … [A191068] It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Rotigotine

Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours....
Approved
Matched Description: … over the course of 24 hours. ... Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease ... It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Sulfaphenazole

Sulfaphenazole is a sulfonamide antibacterial.
Approved
Matched Categories: … combinations of sulfonamides …

Aripiprazole lauroxil

Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of schizophrenia in adult patients. It is a prodrug of aripiprazole, which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors . Affecting about 1% of the...
Approved
Investigational
Matched Description: … schizophrenia resulted in improvement of positive and negative symptoms scores at day 85 of treatment ... for immediate initiation of Aristada at any dose. ... to achieve appropriate levels of aripiprazole more rapidly. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Citric acid

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Description: … The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability ... Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved …
Matched Mixtures name: … Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood …

Dapsone

A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Description: … Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of ... It is also used with pyrimethamine in the treatment of malaria. ... A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium …
Matched Categories: … Drugs for Treatment of Lepra …

Emtricitabine

Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Description: … Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV ... infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection ... [L9019] The drug works by inhibiting HIV reverse transcriptase, preventing transcription of HIV RNA to …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …

Armodafinil

Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists...
Approved
Investigational
Matched Description: … Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. ... Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated ... (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …

Lurasidone

Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Description: … pending approval for the treatment of bipolar disorder in the United States. ... Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Nortriptyline

Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Description: … Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … vitamin d and are found in various types of food for daily intake [L5689]. ... Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin ... Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Fluorometholone

A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Approved
Investigational
Matched Description: … of the eye. ... It has also been used topically in the treatment of various skin disorders. ... A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Hydrochlorothiazide

Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Description: … [A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting …
Matched Categories: … combinations of sulfonamides …

Safinamide

Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
Approved
Investigational
Matched Description: … Safinamide is for the treatment of parkinson's disease. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Wormwood

Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental

Beractant

Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral lipids, fatty acids, and surfactant-associated proteins such as SP-B and SP-C. The...
Approved
Matched Description: … However, in Respiratory Distress Syndrome, developmental deficiency of surfactant results collapse of ... Administration of lung surfactant remains the cornerstone of therapy in this condition that is currently ... the leading cause of death in preterm infants. …

Taurine

Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in several organs. It plays important role in essential biological processes. This conditional amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of fish and...
Approved
Nutraceutical
Matched Description: … Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in ... amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of …
Displaying drugs 201 - 225 of 8023 in total