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Displaying drugs 3601 - 3625 of 6979 in total
Invert sugar is obtained from sugar cane when this is treated with dilute acid or with the invertase enzyme. It is formed by an equal amount of glucose and fructose. It differentiates from sugar cane in the rotation of the polarized light, which in the case of invert sugar it...
Experimental
Matched Description: … It differentiates from sugar cane in the rotation of the polarized light, which in the case of invert ... It is formed by an equal amount of glucose and fructose. …
Camazepam is a benzodiazepine which is a dimethyl carbamate ester of tamzepam, a metabolite of diazepam. Similarly to other drugs in its class, it has antxiolytic, anticonvulsant, hypnotic, and skeletal muscle relaxant properties. However, unlike other benzodiapeines camazepam is predominantly anxiolytic and is relatively weak as an anticonvulsant, hypnotic and...
Experimental
Illicit
Matched Description: … Camazepam is a benzodiazepine which is a dimethyl carbamate ester of tamzepam, a metabolite of diazepam ... However, impairment of cognition and disrupted sleep patterns will occur at doses higher than 40mg of
Polaprezinc is a chelated form of zinc and L-carnosine. It is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1208]. It was determined that polaprezinc may be effective in pressure ulcer treatment . A study in 2013 showed...
Experimental
Matched Description: … Polaprezinc is a chelated form of zinc and L-carnosine. ... A study in 2013 showed that CO-administration of polaprezinc may be effective against small intestine …
Cod liver oil is extracted from the liver of cod fish and mainly consists of omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Also being a rich source of vitamin A and D, cod liver oil can be taken orally as daily supplements. It is used as an...
Nutraceutical
Vet approved
Matched Description: … Cod liver oil is extracted from the liver of cod fish and mainly consists of omega-3 fatty acids, eicosapentaenoic ... Also being a rich source of vitamin A and D, cod liver oil can be taken orally as daily supplements. ... It is used as an adjunct treatment and preventative therapy of rickets, osteomalacia and osteoporosis …
Leronlimab, or PRO-140, is a human monoclonal antibody developed by CytoDyn. It was first described in the literature in 2001. This antibody binds to CCR5, which may be useful in treating HIV, cancers, and severely ill COVID-19 patients.[A192846,A192858,L12684]
Investigational
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland,...
Experimental
Investigational
Matched Description: … of purine salvage. ... It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed) ... A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. …
Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Initially introduced in 1983...
Experimental
GTS-21 (also known as DMBX-A), is a novel, small-molecule, orally active and selective alpha-7 nicotinic acetylcholine (nACh) receptor agonist that has demonstrated memory and cognition enhancement activity in human clinical trials. Athenagen licensed the exclusive rights to the compound and a related library of analogs as part of the acquisition...
Investigational
Matched Description: … Athenagen licensed the exclusive rights to the compound and a related library of analogs as part of the ... acquisition of Osprey Pharmaceutical Company in April 2006. …
XL765 is an orally available small molecule that has been shown in preclinical studies to selectively inhibit the activity of phosphoinositide-3 kinase (PI3K) and mammalian target of rapamycin (mTOR). It is being developed by Exelixis, Inc.
Investigational
Matched Description: … phosphoinositide-3 kinase (PI3K) and mammalian target of rapamycin (mTOR). ... available small molecule that has been shown in preclinical studies to selectively inhibit the activity of
Bentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy. It is typically administered orally. Cases of headache and gastrointestinal disturbances have been reported with the use of bentiromide. Bentiromide is...
Investigational
Withdrawn
Matched Description: … Cases of headache and gastrointestinal disturbances have been reported with the use of bentiromide. ... , which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of
Brasofensine is an orally administered dopamine reuptake inhibitor being developed for the treatment of Parkinson's Disease. Phase I/II trials for brasofensine have been completed in the U.K. In November 2001, NeuroSearch confirmed that the drug's development was discontinued in favor of NS 2230.
Investigational
Matched Description: … Brasofensine is an orally administered dopamine reuptake inhibitor being developed for the treatment of ... In November 2001, NeuroSearch confirmed that the drug's development was discontinued in favor of NS 2230 …
Triazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy against influenza A and B, including the H5N1 strain.[A191709,A191625,A191916] It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications. Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating...
Experimental
Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast cancer.
Investigational
Matched Description: … Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected …
G17DT is a vaccine that neutralises gastrin-17, a hormone required for the growth of a number of cancers of the gastrointestinal tract. It is in phase III trials for advanced pancreatic cancer as a monotherapy and in combination with gemcitabine. It is also in a phase II/III trial for advanced...
Investigational
Matched Description: … of the gastrointestinal tract. ... G17DT is a vaccine that neutralises gastrin-17, a hormone required for the growth of a number of cancers …
Bicifadine (DOV-220075) is a nonopioid analgesic. It is an inhibitor of both the norepinephrine and serotonin transporters and an NMDA antagonist with a non-narcotic profile. Bicifadine was shown to have potent analgesic activity in vivo and was chosen for further development for the treatment of pain.
Investigational
Matched Description: … It is an inhibitor of both the norepinephrine and serotonin transporters and an NMDA antagonist with ... to have potent analgesic activity in vivo and was chosen for further development for the treatment of
Tymazoline is a nasal preparation.
Experimental
Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium channels. It is not approved for use in any country, but is currently in clinical trials in the United States.
Investigational
Matched Description: … Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of
Lobeglitazone is an antidiabetic medication from the thiazolidinedione class of drugs. It primarily functions as an insulin sensitizer by binding and activating Peroxisome Proliferator-Activated Receptors (PPAR) gamma within fat cells. By activating PPAR-gamma and promoting the binding of insulin at fat cells, lobeglitazone thereby has been shown to reduce blood...
Experimental
Matched Description: … Lobeglitazone is an antidiabetic medication from the thiazolidinedione class of drugs. ... By activating PPAR-gamma and promoting the binding of insulin at fat cells, lobeglitazone thereby has ... Lobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being …
Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex with copper ions . Prezatide is used in cosmetic products for the skin and hair. It is known to aid wound healing and its potential applications in chronic obstructive pulmonary disease and metastatic colon cancer...
Experimental
Matched Description: … Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex …
Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex with copper ions . Prezatide is used in cosmetic products for the skin and hair. It is known to aid wound healing and its potential applications in chronic obstructive pulmonary disease and metastatic colon cancer...
Experimental
Matched Description: … Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex …
Metenkefalin is an endogenous opioid and beta-endorphin. It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. Metenkefalin, along with tridecactide, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Experimental
Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist in phase III testing by Rottapharm in Europe only, as U.S. trials have been discontinued. As the D-isomer of loxiglumide, it retains all pharmacological properties of loxiglumide but is more potent.
Investigational
Matched Description: … As the D-isomer of loxiglumide, it retains all pharmacological properties of loxiglumide but is more …
Perospirone is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist. Dainippon Sumitomo Pharma developed perospirone in Japan in 2001 for the treatment of acute schizophrenia and bipolar mania as...
Experimental
Matched Description: … Perospirone is an atypical or second-generation antipsychotic of the azapirone family that antagonizes ... Dainippon Sumitomo Pharma developed perospirone in Japan in 2001 for the treatment of acute schizophrenia …
Cethromycin is a 3-keto (ketolide) derivative of erythromycin A with an 11,12-carbamate group and an O-6-linked aromatic ring system. Cethromycin represents a joint development effort by Abbott Laboratories, Taisho Pharmaceuticals, and Advanced Life Sciences, intended to be marketed under the trade name Restanza for the treatment of community-acquired pneumonia.[L14006, A203369]...
Investigational
Matched Description: … Cethromycin is a 3-keto (ketolide) derivative of erythromycin A with an 11,12-carbamate group and an ... and Advanced Life Sciences, intended to be marketed under the trade name Restanza for the treatment of ... L13988] It has also been investigated, by itself or together with [zoliflodacin], for the treatment of
Displaying drugs 3601 - 3625 of 6979 in total