Displaying drugs 2551 - 2575 of 3034 in total
5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid
Experimental
Matched Name: … 5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid …
Matched Iupac: … 5-[(3-carbamoylphenyl)methyl]-5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-4-carboxylic acid …
Matched Iupac: … 5-[(3-carbamoylphenyl)methyl]-5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-4-carboxylic acid …
4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid
Experimental
Matched Name: … 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid …
Matched Iupac: … 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid …
Matched Iupac: … 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid …
6-{4-[HYDROXY-(4-NITRO-PHENOXY)-PHOSPHORYL]-BUTYRYLAMINO}-HEXANOIC ACID
Experimental
Matched Name: … 6-{4-[HYDROXY-(4-NITRO-PHENOXY)-PHOSPHORYL]-BUTYRYLAMINO}-HEXANOIC ACID …
Matched Iupac: … 6-{4-[hydroxy(4-nitrophenoxy)phosphoryl]butanamido}hexanoic acid …
Matched Iupac: … 6-{4-[hydroxy(4-nitrophenoxy)phosphoryl]butanamido}hexanoic acid …
(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID
Experimental
Matched Name: … (2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID …
Matched Iupac: … (2E)-3-[2-(oct-1-yn-1-yl)phenyl]prop-2-enoic acid …
Matched Iupac: … (2E)-3-[2-(oct-1-yn-1-yl)phenyl]prop-2-enoic acid …
Ceritinib
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … -{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propane …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Tyrosine Kinase Inhibitors ... ROS1 tyrosine kinase inhibitors ... Receptor Protein-Tyrosine Kinases, antagonists & inhibitors …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Tyrosine Kinase Inhibitors ... ROS1 tyrosine kinase inhibitors ... Receptor Protein-Tyrosine Kinases, antagonists & inhibitors …
Dactinomycin
A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Synonyms: … DILACTONE ACTINOMYCIN D ACID ... CARBONYLIMINOISOBUTYLIDENECARBONYL-1,2-PYRROLIDINEDIYLCARBONYL(METHYLIMINO)METHYLENECARBONYL))BIS(N-METHYL-L-VALINE …
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances ... Nucleic Acid Synthesis Inhibitors …
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances ... Nucleic Acid Synthesis Inhibitors …
Simvastatin
Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production...
Approved
Matched Synonyms: … 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy …
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid ... belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... referred to as "bad cholesterol"), and very low-density lipoprotein (VLDL). …
Matched Mixtures name: … Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin …
Matched Categories: … simvastatin and acetylsalicylic acid ... simvastatin, acetylsalicylic acid and ramipril ... simvastatin and ezetimibe ... sitagliptin and simvastatin ... simvastatin and fenofibrate …
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid ... belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... referred to as "bad cholesterol"), and very low-density lipoprotein (VLDL). …
Matched Mixtures name: … Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin …
Matched Categories: … simvastatin and acetylsalicylic acid ... simvastatin, acetylsalicylic acid and ramipril ... simvastatin and ezetimibe ... sitagliptin and simvastatin ... simvastatin and fenofibrate …
Diaziquone
Investigational
Matched Synonyms: … Carbamic acid, (2,5-bis(1-aziridinyl)-3,6-dioxo-1,4-cyclohexadiene-1,4-diyl)bis-, diethyl ester …
Matched Categories: … Indicators and Reagents …
Matched Categories: … Indicators and Reagents …
TAK-603
Investigational
Matched Synonyms: … 3-quinolinecarboxylic acid, 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1h-1,2,4-triazol-1-ylmethyl)-, ethyl …
Domperidone
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … SERONEX …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … SERONEX …
Cilostazol
Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reducing...
Approved
Investigational
Matched Description: … Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been ... Cilostazol works by inhibiting both primary and secondary aggregation and reducing calcium-induced contractions …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … VALINTA …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … VALINTA …
Lonigutamab
Lonigutamab is under investigation in clinical trial NCT05683496 (Efficacy and Safety of Lonigutamab in Subjects With Thyroid Eye Disease (TED)).
Investigational
Matched Synonyms: … Immunoglobulin g1 (de-c-terminal-lysine), anti-(human insulin-like growth factor i receptor) (human-mus …
Matched Description: … Lonigutamab is under investigation in clinical trial NCT05683496 (Efficacy and Safety of Lonigutamab …
Matched Description: … Lonigutamab is under investigation in clinical trial NCT05683496 (Efficacy and Safety of Lonigutamab …
Pantoprazole
Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Description: … [FDA Label]
Due to their good safety profile and as several PPIs are available over the counter without ... This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of ... Pantoprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid …
Matched Categories: … Alimentary Tract and Metabolism ... Acid Reducers ... pantoprazole, amoxicillin and clarithromycin ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... pantoprazole, amoxicillin, clarithromycin and metronidazole …
Matched Products: … PANTOPRAZOL ACIS 40MG ... PANTOPRAZOL ACIS 20MG …
Matched Categories: … Alimentary Tract and Metabolism ... Acid Reducers ... pantoprazole, amoxicillin and clarithromycin ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... pantoprazole, amoxicillin, clarithromycin and metronidazole …
Matched Products: … PANTOPRAZOL ACIS 40MG ... PANTOPRAZOL ACIS 20MG …
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE
Experimental
Matched Name: … N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE …
Matched Iupac: … (2S)-2-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-methylpentanamido]propanoic acid …
Matched Iupac: … (2S)-2-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-methylpentanamido]propanoic acid …
3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene
Experimental
Matched Name: … 3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene …
Chlorphenesin
Approved
Experimental
Matched Synonyms: … 3-(p-chlorophenoxy)propane-1,2-diol …
Matched Iupac: … 3-(4-chlorophenoxy)propane-1,2-diol …
Matched Iupac: … 3-(4-chlorophenoxy)propane-1,2-diol …
Moricizine
An antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Approved
Investigational
Withdrawn
Matched Synonyms: … [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester …
(3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine
Experimental
Matched Name: … (3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine …
Matched Iupac: … (3,4-dihydroxyphenyl)acetyl]oxy}-2-[(2-formylindolizin-3-yl)amino]-3-methyl-3-[(S)-sulfino]butanoic acid …
Matched Iupac: … (3,4-dihydroxyphenyl)acetyl]oxy}-2-[(2-formylindolizin-3-yl)amino]-3-methyl-3-[(S)-sulfino]butanoic acid …
Hexobarbital
A barbiturate that is effective as a hypnotic and sedative.
Experimental
Matched Synonyms: … 5-(1-cyclohexen-1-yl)-1,5-dimethylbarbituric acid …
Matched Description: … A barbiturate that is effective as a hypnotic and sedative. …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … A barbiturate that is effective as a hypnotic and sedative. …
Matched Categories: … Hypnotics and Sedatives …
Meningococcal polysaccharide vaccine group C
Meningococcal group C polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup C. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup C.
Approved
Experimental
Investigational
Matched Synonyms: … Neisseria meningitidis group C (strain C11) oligosaccharide CRM-197 adipic acid conjugate …
Matched Description: … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia ... Meningococcal group C polysaccharide is group-specific polysaccharide antigens extracted and purified …
Matched Mixtures name: … Menveo Powder and Solution for Solution for Injection ... NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Nimenrix Powder and Solvent for Solution for Injection …
Matched Description: … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia ... Meningococcal group C polysaccharide is group-specific polysaccharide antigens extracted and purified …
Matched Mixtures name: … Menveo Powder and Solution for Solution for Injection ... NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Nimenrix Powder and Solvent for Solution for Injection …
Dicloxacillin
One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Synonyms: … methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … dichlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … dichlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Epoprostenol
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Approved
Matched Synonyms: … (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid …
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-ylidene]pentanoic acid …
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. …
Matched Categories: … Blood and Blood Forming Organs ... Fatty Acids ... Fatty Acids, Unsaturated …
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-ylidene]pentanoic acid …
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. …
Matched Categories: … Blood and Blood Forming Organs ... Fatty Acids ... Fatty Acids, Unsaturated …
Sodium citrate
Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water,
practically insoluble in alcohol. Like citric acid, it has a sour taste.
From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Synonyms: … Citric acid, trisodium salt …
Matched Description: … It works by neutralizing excess acid in the blood and urine. ... Sodium citrate is the sodium salt of citric acid. ... Like citric acid, it has a sour taste. …
Matched Mixtures name: … Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid …
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Diet, Food, and Nutrition ... Acids, Acyclic …
Matched Description: … It works by neutralizing excess acid in the blood and urine. ... Sodium citrate is the sodium salt of citric acid. ... Like citric acid, it has a sour taste. …
Matched Mixtures name: … Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid …
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Diet, Food, and Nutrition ... Acids, Acyclic …
1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane
Experimental
Matched Name: … 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane …
Matched Iupac: … carboxymethyl)carbamoyl]-2-{[(2S)-1-hydroxy-3-(4-nitrophenoxy)propan-2-yl]sulfanyl}ethyl]carbamoyl}butanoic acid …
Matched Iupac: … carboxymethyl)carbamoyl]-2-{[(2S)-1-hydroxy-3-(4-nitrophenoxy)propan-2-yl]sulfanyl}ethyl]carbamoyl}butanoic acid …
N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Experimental
Matched Name: … N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine …
Displaying drugs 2551 - 2575 of 3034 in total