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Displaying drugs 2726 - 2750 of 7490 in total

Cofirasersen

Cofirasersen is under investigation in clinical trial NCT04441788 (A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB)).
Investigational
Matched Synonyms: … DNA, D(P-THIO)((2',5'-ANHYDRO-6'-DEOXY-4'-C-(HYDROXYMETHYL)-.ALPHA. ... -L-MANNOFURANO)M5C-(3'->4')-(2',5'-ANHYDRO-6'-DEOXY-4'-C-(HYDROXYMETHYL)-.ALPHA. ... -L-MANNOFURANO)M5C-(3'->4')-(2',5'-ANHYDRO-6'-DEOXY-4'-C-(HYDROXYMETHYL)-.ALPHA. …

naphthalene-1,2,4,5,7-pentol

Experimental

PA3-17

PA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy.
Investigational

C-(1-hydrogyl-beta-D-glucopyranosyl) formamide

Experimental

8-oxo-dGMP

Experimental
Matched Synonyms: … 2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid ... 8-hydroxydeoxyguanosine 5'-monophosphate ... 8-oxo-2'-deoxyguanosine-5'-monophosphate …
Matched Iupac: … {[(2R,3S,5R)-5-(6,8-dihydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …

Chrysin

Experimental

EHP-102

Investigational
Matched Synonyms: … 2-(3,7-Dimethyl-Octa-2, 6-Dienyl)-6-Ethylamino-3-Hydroxy-5-Pentyl-[1,4]Benzoquinone ... 2-(3,7-Dimethyl-octa-2, 6-dienyl)¿6-ethylamino-3-hydroxy-5-pentyl-[1,4]benzoquinone ... 2-((2e)-3,7-dimethyl-2,6-octadien-1-yl)-6-(ethylamino)-3-hydroxy-5-pentyl-2,5-cyclohexadiene-1,4-dione …
Matched Iupac: … 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-6-(ethylamino)-3-hydroxy-5-pentylcyclohexa-2,5-diene-1,4-dione …

beta-D-Ribose-5-phosphate

Experimental
Matched Synonyms: … β-D-ribofuranose 5-phosphate ... 5-O-phosphono-β-D-ribofuranose ... 5-O-phosphono-beta-D-ribofuranose …
Matched Name: … beta-D-Ribose-5-phosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methoxy}phosphonic acid …

Oxypurinol

Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
Investigational

Dethiobiotin

Experimental
Matched Synonyms: … (4R-cis)-5-methyl-2-oxo-4-imidazolidinehexanoic acid ... (4R,5S)-5-methyl-2-oxo-4-imidazolidinehexanoic acid …
Matched Iupac: … 6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanoic acid …

Vantictumab

Vantictumab has been used in trials studying the treatment of Solid Tumors, Pancreatic Cancer, and Stage IV Pancreatic Cancer.
Investigational

Olezarsen

Olezarsen is an antisense oligonucleotide targeting messenger RNA for apolipoprotein C-III (APOC3).
Investigational
Matched Synonyms: … ALL-P-AMBO-5'-O-(((6-(5-((TRIS(3-(6-(2-ACETAMIDO-2-DEOXY-.BETA. ... 2'-O-(2-METHOXYETHYL)-P-THIOADENYLYL-(3'-O->5'-O)-2'-O-(2-METHOXYETHYL)-P-THIOGUANYLYL-(3 ... -D-GALACTOPYRANOSYLOXY)HEXYLAMINO)-3-OXOPROPOXYMETHYL))METHYL)AMINO-5-OXOPENTANAMIDO)HEXYL))PHOSPHO)- …

Lomvastomig

Lomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus).
Investigational

ABSK-091

Investigational
Matched Synonyms: … Benzamide, n-(5-(2-(3,5-dimethoxyphenyl)ethyl)-1h-pyrazol-3-yl)-4-((3r,5s)-3,5-dimethyl-1-piperazinyl …
Matched Iupac: … N-{5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl}-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]benzamide …

B7-H3-specific chimeric antigen receptor T cells

Investigational

Mitsugumin-53

Investigational

AUM-601

AUM-601 is a highly selective pan-TRK(tropomyosin receptor kinase). It is currently being investigated in clinical trials for the treatment of cancer.
Investigational

SB 224289

SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.
Investigational
Matched Synonyms: … (1'-methyl-6,7-dihydro-5h-spiro(furo(2,3-f)indole-3,4'-piperidin)-5-yl)(2'-methyl-4'-(5-methyl-1,2,4- ... 6,7-dihydro-1'-methyl-5-((2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-yl)carbonyl)spiro ... Spiro(2h-furo(2,3-f)indole-3(5h),4'-piperidine), 6,7-dihydro-1'-methyl-5-((2'-methyl-4'-(5-methyl-1,2,4 …
Matched Iupac: … 1'-methyl-5-[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carbonyl]-2,5,6,7-tetrahydrospiro …
Matched Description: … SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122] …

PAT-SM6

Investigational

Coptisine

Investigational
Matched Synonyms: … 6,7-dihydrobis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizinium ... Bis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizinium, 6,7-dihydro- …

BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIAZOLO[3,2-C]PYRIMIDINE-2-CARBOXYLATE

Experimental

Smilagenin

Smilagenin is a novel non-peptide, orally bioavailable neurotrophic factor inducer that readily reverses free radical neurotoxicity produced by 1-ethyl-4- phenylpyridium (MPP+) in dopaminergic neurones and reverses the decrease of neuronal growth factors and dopamine receptors in the brain. Pre-clinical work with smilagenin showed it to be neuroprotective against betya-amyloid and...
Investigational
Matched Iupac: … (1'R,2R,2'S,4'S,5R,7'S,8'R,9'S,12'S,13'S,16'S,18'R)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo …

CB-5083

Investigational

N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE

Experimental
Matched Name: … N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C] …
Matched Iupac: … 5-chloro-N-[(1R,2R)-2-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-2-amido}cyclohexyl]-1H-indole …

COTI-2

Investigational
Displaying drugs 2726 - 2750 of 7490 in total