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Displaying drugs 276 - 300 of 620 in total

Antihemophilic factor, human recombinant

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … KOVALTRY POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL ... KOVALTRY POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... ADVATE 250 IU Powder and Solvent for Solution for Injection …

Turoctocog alfa

Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and ... [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid 720, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …

Reteplase

Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature …

MM-111

MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

CLL1-CD33 compound chimeric antigen receptor T cells

Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …

Aluminum chlorohydrate

Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Categories: … Astringents and Deodorants ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Degree Shower Clean Aerosol Antiperspirant and Deodorant ... Degree Sport Aerosol Antiperspirant and Deodorant ... Suave Sweet Pea and Violet Antiperspirant and Deodorant …

Carbidopa

Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Description: … It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …

DCVAC/OvCa

DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …

CHF5633

CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Romilkimab

Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational
Matched Synonyms: … Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13) …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in …

Streptococcus salivarius

Investigational
Matched Synonyms: … Streptococcus salivarius andrewes and horder, 1906 …

Hydrocodone

Hydrocodone is a synthetic opioid derivative of codeine. It is commonly used in combination with acetaminophen to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by dextromethorphan in current cough and cold formulations. Hydrocodone's more potent metabolite, hydromorphone...
Approved
Illicit
Investigational
Matched Description: … a cough suppressant although this has largely been replaced by [dextromethorphan] in current cough and ... Hydrocodone's more potent metabolite, [hydromorphone] has also found wide use as an analgesic and is …
Matched Mixtures name: … Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate and Acetaminophen …
Matched Categories: … Cough and Cold Preparations ... hydrocodone and ibuprofen ... Opium Alkaloids and Derivatives ... hydrocodone and paracetamol …
Matched Products: … Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate And Acetaminophen …

Salicylic acid

A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically ... It has bacteriostatic, fungicidal, and keratolytic actions. …
Matched Mixtures name: … Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Clean and Clear Advantage Acne Control …
Matched Categories: … Salicylic Acid and Derivatives ... Genito Urinary System and Sex Hormones ... sodium salicylate and methenamine …
Matched Products: … ELF Conceler Pencil and Brush ... Acne and Blemish Target ... Equate Corn and Callus Remover …

Sunflower oil

Sunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Products: … OrgaPlus Super Care Balm for combination and oi ly skin type 20g ... OrgaPlus Super Care Balm for combination and oi ly skin type 14g …

Hydroquinone

Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration ... As a result of these concerns, hydroquinone has been banned in the EU and UK. ... with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and …
Matched Mixtures name: … OLIVIA QUIDO FIRM and FADE I ... OLIVIA QUIDO FIRM and FADE II ... Condition and Enhance System Travel-size Non-surgical …
Matched Products: … CONDITION AND ENHANCE CLEAR Skin Bleaching and Corrector ... CONDITION AND ENHANCE BLENDER Skin Lightener and Blending ... Fair and White …

Wormwood

Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Products: … Seborrheic Dermatitis and Psoriasis ... Seborrheic Dermatitis and Psoriasis Cream …

Acetaminophen

Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Description: … tablets, injection, suppository, and other forms. ... of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines ... Acetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and …
Matched Mixtures name: … Benylin Extra Strength Mucus & Phlegm Plus Cold Relief ... Benylin Extra Strength Mucus & Phlegm Plus Cold Relief ... Benylin Extra Strength Mucus & Phlegm Plus Cold Relief Night …
Matched Categories: … Acetaminophen and Prodrugs ... tramadol and paracetamol ... codeine and paracetamol ... oxycodone and paracetamol ... hydrocodone and paracetamol …
Matched Products: … Pain and Fever ... Up and Up Dye Free Infants Pain and Fever Acetaminophen ... Childrens Dimetapp Fever and Sore Throat …

Chorionic Gonadotropin (Human)

Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to continuously secrete the hormone progesterone during the first...
Approved
Vet approved
Matched Description: … HCG is composed of an alpha and a beta sub-unit. ... Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance ... the hormone progesterone during the first trimester, which is required for maintenance of the uterus and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Powder and Solvent for Solution for Injection ... Choriomon 5000 IU powder and solvent for solution for injection ... PUBERGEN 5000IU (Chorionic Gonadotropin for Injection USP 5000IU/Vial and Sodium Chloride Injection USP …

Carbamide peroxide

Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Some adverse effects of carbamide peroxide as a dental bleaching agent include...
Approved
Matched Description: … /or gingival irritation led by unstable and reactive H+ free radicals and low pH from prolonged use. ... urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and ... As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products …
Matched Products: … Ear Wax Removal Drops Up and Up ... CareOne Earwax Removal Kit, Earwax and Bulb ... Foster and Thrive Earwax Removal Drops …

ARGX-119

ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Investigational
Matched Synonyms: … humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and …
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …

Aluminum zirconium pentachlorohydrate

Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … Skin So Soft Soft and Sensual Anti-Perspirant Deodorant ... Skin So Soft Fresh and Smooth Moisturizing Hair Minimizing Anti-Perspirant Deodorant …

Omalizumab

Omalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). IgE promotes the release of inflammatory mediators from mast cells and basophils during allergic and inflammatory reactions. By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its...
Approved
Investigational
Matched Description: … , and asthma. ... and inflammatory reactions. ... By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xolair 75mg Powder and Solvent for Solution for Injection ... Xolair 150mg Powder and Solvent for Solution for Injection ... XOLAIR 150MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

VOR33

VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …

Antihemophilic factor human

Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Description: … as a result, leads to easy bruising and bleeding. ... for the prophylaxis and control of bleeding episodes. ... AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and …
Matched Mixtures name: … Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection ... Haemate P Powder and solvent for solution for injection or infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Octanate 500IU Powder and Solvent for Solution for Injection ... Octanate 250IU Powder and Solvent for Solution for Injection ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Displaying drugs 276 - 300 of 620 in total