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Displaying drugs 26 - 50 of 313 in total
Experimental
Matched Name: … [[4-(Aminomethyl)Phenyl]Amino]Oxo-Acetic Acid, …
Matched Iupac: … {[4-(aminomethyl)phenyl]carbamoyl}formic acid
A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Approved
Matched Synonyms: … Acetic acid 4-(2-hydroxy-3-isopropylamino-propoxy)-2,3,6-trimethyl-phenyl ester …
WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.
Investigational
Matched Synonyms: … an acetic acid diester of 2-deoxy-D-glucose …
Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with...
Approved
Investigational
Matched Synonyms: … {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid
Matched Description: … of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with diuretic-induced ... Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia ... It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake …
Matched Categories: … Preparations Increasing Uric Acid Excretion …
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild,...
Approved
Vet approved
Withdrawn
Matched Synonyms: … (±)-6-chloro-α-methylcarbazole-2-acetic acid ... 6-chloro-α-methyl-9H-carbazole-2-acetic acid ... 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid
Matched Iupac: … 2-(6-chloro-9H-carbazol-2-yl)propanoic acid
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid ... 2-amino-3-(4-bromobenzoyl)benzeneacetic acid
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Experimental
Matched Name: … N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID
Matched Iupac: … 2-[(Z)-{[(4-cyanophenyl)amino][(diphenylmethyl)amino]methylidene}amino]acetic acid
Experimental
Matched Synonyms: … (2,6-Xylyloxy) acetic acid
Matched Name: … (2,6-Dimethylphenoxy)acetic acid
Matched Iupac: … 2-(2,6-dimethylphenoxy)acetic acid
Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension. It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Withdrawn
Matched Synonyms: … (2,3-Dichloro-4-(2-thenoyl)phenoxy)acetic acid ... (2,3-Dichloro-4-(2-thiophenecarbonyl)phenoxy)acetic acid ... Tienilic acid
Matched Name: … Tienilic acid
Matched Iupac: … 2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid
Matched Description: … Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for …
Matched Categories: … tienilic acid ... Aryloxyacetic Acid Derivatives …
Investigational
Matched Synonyms: … acid ... acid ... acid
Matched Iupac: … acid ... 2-{3-[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic
Experimental
Matched Synonyms: … 2-(Hexadecanoylamino)acetic acid ... Elmiric acid
Matched Iupac: … 2-hexadecanamidoacetic acid
Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Experimental
Matched Synonyms: … (2S)-Amino(4-Hydroxyphenyl)Acetic Acid
Matched Iupac: … (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid
Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and congestive heart failure.
Investigational
Matched Synonyms: … acid ... Ethoxycarbonyl-4-phenylbutyl)cyclopentanecarboxamido}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)acetic
Matched Iupac: … acid ... ethoxy-3-oxo-2-(2-phenylethyl)propyl]cyclopentaneamido}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic
A deaminated metabolite of levodopa. [PubChem]
Experimental
Matched Name: … 2-(3,4-Dihydroxyphenyl)Acetic Acid
Matched Iupac: … 2-(3,4-dihydroxyphenyl)acetic acid
Alclofenac is a non-steroidal anti-inflammatory drug. It was withdrawn from the market in the United Kingdom in 1979.
Approved
Withdrawn
Matched Synonyms: … [4-(allyloxy)-3-chlorophenyl]acetic acid ... 3-Chloro-4-(2-propenyloxy)benzeneacetic acid
Matched Iupac: … 2-[3-chloro-4-(prop-2-en-1-yloxy)phenyl]acetic acid
Matched Categories: … Acetic Acid Derivatives and Related Substances …
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...
Approved
Investigational
Matched Synonyms: … (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid ... Etacrinic acid ... Etacrynic acid
Matched Name: … Etacrynic acid
Matched Iupac: … 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
Matched Categories: … etacrynic acid ... Aryloxyacetic Acid Derivatives …
Matched Products: … Ethacrynic Acid ... Ethacrynic acid
Investigational
Matched Synonyms: … 2-{2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-6-pentylphenyl}acetic acid
Matched Name: … Cannabidiolic acid methyl ester …
Matched Iupac: … 2-{2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-6-pentylphenyl}acetic acid
Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia).
Investigational
Matched Synonyms: … acid ... 4-chlorophenyl)-3-methyl-1-[ (2S)-3 -methyl-1-(propan-2- ylsulfonyl)butan-2-yl]-2-oxopiperidin-3-yl}acetic
Matched Iupac: … acid ... -6-(4-chlorophenyl)-3-methyl-1-[(2S)-3-methyl-1-(propane-2-sulfonyl)butan-2-yl]-2-oxopiperidin-3-yl]acetic
Experimental
Matched Name: … 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID
Matched Iupac: … 2-[1-(4-iodobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Experimental
Matched Name: … 2-Amino-3-(Cystein-S-Yl)-Isoxazolidin-5-Yl-Acetic Acid
Matched Iupac: … (2R)-2-amino-3-{[(3R,5R)-5-[(S)-amino(carboxy)methyl]-1,2-oxazolidin-3-yl]sulfanyl}propanoic acid
Investigational
Matched Synonyms: … Dimethyloxoxanthene acetic acid ... 5,6-Dimethylxanthenone-4-acetic acid ... (5,6-dimethyl-9-oxoxanthen-4-yl)acetic acid
Matched Iupac: … 2-(5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
Investigational
Matched Synonyms: … acid ... acid ... ethoxy]-ethoxy}-ethoxy)-ethyl]-1H-[1,2,3]triazol-4-ylmethoxy}-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-acetic
Matched Iupac: … acid ... 3,6,9,12,15,18-hexaoxaicosan-1-yl}-1H-1,2,3-triazol-4-yl)methoxy]-3,5-diiodophenoxy}-3,5-diiodophenyl)acetic
A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Approved
Matched Synonyms: … 1-Methyl-5-p-toluoylpyrrole-2-acetic acid ... 5-(p-Toluoyl)-1-methylpyrrole-2-acetic acid ... 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid
Matched Iupac: … 2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid
Matched Categories: … Heteroaryl acetic acid NSAIDS ... Acetic Acid Derivatives and Related Substances …
Experimental
Matched Name: … (1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid
Matched Iupac: … 2-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid
Experimental
Matched Synonyms: … D-(-)-amino(4-hydroxyphenyl)acetic acid ... D-2-amino-2-(p-hydroxyphenyl)acetic acid ... (R)-alpha-Amino-4-hydroxybenzeneacetic acid
Matched Iupac: … (2R)-2-amino-2-(4-hydroxyphenyl)acetic acid
Displaying drugs 26 - 50 of 313 in total