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Displaying drugs 551 - 575 of 785 in total
Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). Widespread resistance has limited the utility of sodium stibogluconate,...
Approved
Investigational
Matched Synonyms: … Antimony sodium gluconate ... Antimony (V) derivative of sodium gluconate …
Matched Description: … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration ... Widespread resistance has limited the utility of sodium stibogluconate, and in many parts of the world …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents ... Antimony Compounds …
Integrins are important adhesion molecules that regulate tumor and endothelial cell survival, proliferation and migration. The integrin alpha5beta1 has been shown to play a critical role during angiogenesis. anti-alpha5beta1 integrin antibody inhibits angiogenesis, including vessel formation induced by vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), as well...
Investigational
Matched Name: … anti-alpha5Beta1-integrin antibody
Matched Description: … and migration. ... Integrins are important adhesion molecules that regulate tumor and endothelial cell survival, proliferation ... integrin alpha5beta1 has been shown to play a critical role during angiogenesis. anti-alpha5beta1 integrin antibody
Investigational
Matched Synonyms: … Humanized monoclonal antibody Hu11E6 …
Matched Name: … Humanized monoclonal antibody Hu11E6 …
Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. Human Genome Sciences modified interferon alpha to improve its pharmacological properties by using the company's proprietary albumin fusion technology. Human...
Investigational
Matched Synonyms: … alb-IFN …
Matched Description: … Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range ... In response to an FDA ruling, Novartis and Human Genome Sciences announced on October 5, 2010 that they …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Investigational
Matched Synonyms: … Humanized monoclonal antibody Hu1B7 …
Matched Name: … Humanized monoclonal antibody Hu1B7 …
Apricot kernel oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Armeniaca Vulgaris Oil …
Experimental
Matched Synonyms: … CC49 monoclonal antibody ... Monoclonal antibody CC49 …
CTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell maturation antigen.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting B-cell maturation antigen …
Matched Description: … CTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell …
Barley malt syrup allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Sprouted hordeum vulgare oligosaccharide extract …
Pisum sativum whole allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Pisum album whole ... Pisum vulgare whole …
Experimental
Matched Name: … Calcium magnesium potassium carbonate chloride hydroxide …
Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. It was first approved by the FDA in...
Approved
Matched Synonyms: … 2C4 Antibody ... Monoclonal Antibody 2C4 …
Matched Description: … It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. ... It was first approved by the FDA in 2012 for use with [docetaxel] and another HER2-targeted monoclonal ... Its indicated conditions have since expanded to include use as both a neoadjuvant therapy and an adjuvant …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... pertuzumab and trastuzumab …
BB-1701 is a humanized IgG1 kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin developed by Bliss Biopharmaceutical.
Investigational
Matched Synonyms: … Humanized IgG1kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin …
Matched Description: … BB-1701 is a humanized IgG1 kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin developed …
Investigational
Matched Synonyms: … Monoclonal antibody targeting CCL24 ... Monoclonal antibody targeting eotaxin-2 …
The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational
Matched Name: … humanized SMART Anti-IL-12 Antibody
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized …
Anti-GD2 monoclonal antibody 3F8 is under investigation in clinical trial NCT00089258 (Biological Therapy in Treating Patients With Neuroblastoma That Has Not Responded to Previous Treatment).
Investigational
Matched Synonyms: … MONOCLONAL ANTIBODY 3F8 ... ANTI-GD2 MOUSE MONOCLONAL ANTIBODY 3F8 (IGG3) …
Matched Name: … Anti-GD2 monoclonal antibody 3F8 …
Matched Description: … Anti-GD2 monoclonal antibody 3F8 is under investigation in clinical trial NCT00089258 (Biological Therapy …
Lactuca sativa whole allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Lactuca crispa whole ... Lactuca sativa crispa whole …
Naxitamab (humanized 3F8, hu3F8) is an IgG1 monoclonal antibody directed against the oncofetal differentiation antigen GD2 disialoganglioside.[L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and skin cells, GD2 constitutes a highly efficient target in the treatment of neuroblastoma - it is widely expressed across and within...
Approved
Matched Synonyms: … Monoclonal antibody HU3F8 ... Anti-Gd2 monoclonal antibody 3F8 humanized ... Humanized monoclonal antibody HU3F8-IGG1 …
Matched Description: … [L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and ... within neuroblastomas (and other neuroectodermal tumors),[A224609] and is rarely subject to antigen ... constitutes a highly efficient target in the treatment of neuroblastoma - it is widely expressed across and
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Glycolipid Disialoganglioside-directed Antibody ... Glycolipid Disialoganglioside-directed Antibody Interactions …
Investigational
Matched Synonyms: … Monoclonal antibody PM-81 ... Anti-CD15 monoclonal antibody PM-81 ... Anti-AML/SCCL-trigger monoclonal antibody
A macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 antibody.
Investigational
Matched Name: … anti-OX40 antibody BMS 986178 …
Matched Description: … A macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 ... antibody. …
There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Synonyms: … Anti-VEGF monoclonal antibody ... Anti-VEGF Humanized Monoclonal Antibody
Matched Description: … [A193272,A193275] It is a humanized monoclonal IgG antibody, and inhibits angiogenesis by binding and ... of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and ... [A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Vascular Endothelial Growth Factor-directed Antibody Interactions …
2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.
Investigational
Matched Synonyms: … Anti-TGF-beta antibody 2G7 ... Anti-TGF-beta monoclonal antibody 2G7 ... Anti-transforming growth factor-beta monoclonal antibody 2G7 …
Matched Description: … 2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech. …
Immunoglobulin G1, anti-(human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with human monoclonal MDX-060 light chain, dimer. Molecular weight is approximately 170,000 daltons. In phase I/II clinical trials for treatment of CD30+ lymphomas.
Investigational
Matched Synonyms: … 5F11 monoclonal antibody
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … anti-Cd33 monoclonal antibody BI 836858 ... Fully Human Igg1 Antibody Specific For Cd33 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Melilotus albus pollen is the pollen of the Melilotus albus plant. Melilotus albus pollen is mainly used in allergenic testing.
Approved
Matched Name: … Melilotus albus pollen …
Matched Description: … Melilotus albus pollen is the pollen of the Melilotus albus plant. ... Melilotus albus pollen is mainly used in allergenic testing. …
Displaying drugs 551 - 575 of 785 in total