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Displaying drugs 7326 - 7350 of 12349 in total

AP5346

AP5346 is designed to target a diaminocyclohexane platinum (Pt) moiety to tumors through pH-sensitive linkage to a 25 kDa hydroxypropylmethacrylamide polymer. It is being pursued by Access Pharmaceuticals, Inc.
Investigational

AP5280

AP5280 is a novel N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-bound platinum (Pt) therapeutic designed to increase the therapeutic index relative to conventional, small-molecule platinum agents.
Investigational

L523S

According to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S) and when delivered following incorporation into an E1B-deleted adenovirus (Ad/L523S)." It has been investigated as a lung cancer vaccine.
Investigational

P-57AS3

Investigational
Matched Iupac: … (1S,3aS,3bR,7S,9aR,9bS,11R,11aS)-1-acetyl-7-{[(2R,4S,5R,6R)-5-{[(2S,4S,5R,6R)-5-{[(2S,3R,4S,5R,6R)-3,5 ... -dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2 …

GC5107

GC5107 is an investigational intravenous immunoglobulin. It is marketed as IVIG-SN.
Investigational

Isoferulic acid

Experimental
Matched Iupac: … (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid …

(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE

Experimental
Matched Iupac: … 4-benzoyl-3-nitrobenzene-1,2-diol …

6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE

Experimental
Matched Iupac: … 4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol …

Ruplizumab

Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.
Investigational

5-methylcytidine 5'-monophosphate

Experimental
Matched Synonyms: … 5-methylcytidine-5'-monophosphate ... 5-methyl-CMP ... 5-methylcytidylic acid …
Matched Name: … 5-methylcytidine 5'-monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

2-Oxy-4-Hydroxy-5-(2-Hydrazinopyridine)Phenylalanine

Experimental
Matched Name: … 2-Oxy-4-Hydroxy-5-(2-Hydrazinopyridine)Phenylalanine …
Matched Iupac: … (2S)-2-amino-3-[(1R)-4-hydroxy-6-oxo-3-[2-(pyridin-2-yl)hydrazin-1-yl]cyclohexa-2,4-dien-1-yl]propanoic …

2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid

Experimental
Matched Name: … 2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid …
Matched Iupac: … 2-{[3,5-dichloro-4-(hydroxyperoxy)phenyl]amino}benzoic acid …

HH-009

HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.
Investigational

4-[(CYCLOPROPYLETHYNYL)OXY]-6-FLUORO-3-ISOPROPYLQUINOLIN-2(1H)-ONE

Experimental
Matched Name: … 4-[(CYCLOPROPYLETHYNYL)OXY]-6-FLUORO-3-ISOPROPYLQUINOLIN-2(1H)-ONE …
Matched Iupac: … 4-[(2-cyclopropylethynyl)oxy]-6-fluoro-3-(propan-2-yl)-1,2-dihydroquinolin-2-one …

Debromohymenialdisine

Experimental
Matched Iupac: … 2-amino-5-[(4Z)-8-oxo-1H,4H,5H,6H,7H,8H-pyrrolo[2,3-c]azepin-4-ylidene]-4,5-dihydro-1H-imidazol-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

L-xylitol 5-phosphate

Experimental
Matched Synonyms: … Xylitol 5-P ... Xylitol 5-phosphate …
Matched Name: … L-xylitol 5-phosphate …

5'-Deoxy-5'-(Methylthio)-Tubercidin

Experimental
Matched Name: … 5'-Deoxy-5'-(Methylthio)-Tubercidin …
Matched Iupac: … (2R,3R,4S,5S)-2-{4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-[(methylsulfanyl)methyl]oxolane-3,4-diol …

Nigericin

A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)
Experimental
Matched Iupac: … (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-[(2S,2'R,3'S,5R,5'R)-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl ... )-3,5-dimethyloxan-2-yl]-2,3'-dimethyl-[2,2'-bioxolan]-5-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Insulin efsitora alfa

Insulin efsitora alfa is under investigation in clinical trial NCT05662332 (A Study of Insulin Efsitora Alfa (LY3209590) Compared to Glargine in Adult Participants With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time (QWINT-1)).
Investigational
Matched Description: … in Adult Participants With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time (QWINT-1) …

N-Methyl-N-[3-(6-Phenyl[1,2,4]Triazolo[4,3-B]Pyridazin-3-Yl)Phenyl]Acetamide

Experimental

2,4-Dihydroxybenzoic Acid

Experimental

Smilagenin

Smilagenin is a novel non-peptide, orally bioavailable neurotrophic factor inducer that readily reverses free radical neurotoxicity produced by 1-ethyl-4- phenylpyridium (MPP+) in dopaminergic neurones and reverses the decrease of neuronal growth factors and dopamine receptors in the brain. Pre-clinical work with smilagenin showed it to be neuroprotective against betya-amyloid and...
Investigational
Matched Iupac: … (1'R,2R,2'S,4'S,5R,7'S,8'R,9'S,12'S,13'S,16'S,18'R)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo …
Matched Description: … bioavailable neurotrophic factor inducer that readily reverses free radical neurotoxicity produced by 1- ... ethyl-4- phenylpyridium (MPP+) in dopaminergic neurones and reverses the decrease of neuronal growth …

P-Hydroxybenzaldehyde

Experimental
Matched Iupac: … 4-hydroxybenzaldehyde …

(5R)-5-{[(2-Amino-3H-purin-6-yl)oxy]methyl}-2-pyrrolidinone

Experimental
Matched Name: … (5R)-5-{[(2-Amino-3H-purin-6-yl)oxy]methyl}-2-pyrrolidinone …
Matched Iupac: … (5R)-5-{[(2-amino-9H-purin-6-yl)oxy]methyl}pyrrolidin-2-one …

E5531

E5531 is an endotoxin antagonist.
Investigational
Matched Iupac: … {[(2R,3S,4R,5R,6R)-4-{[(3R)-3-[(5Z)-dodec-5-enoyloxy]decyl]oxy}-6-{[(2R,3S,4R,5R,6R)-3-hydroxy-4-{[(3R ... )-3-hydroxydecyl]oxy}-5-(3-oxotetradecanamido)-6-(phosphonooxy)oxan-2-yl]methoxy}-2-(methoxymethyl)-5 …
Displaying drugs 7326 - 7350 of 12349 in total