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Displaying drugs 7501 - 7525 of 8211 in total

Thioctic acid tromethamine

A salt of alpha-lipoic acid and tromethamine; may be useful in treating vascular stress in patients with diabetes.
Investigational
Matched Iupac: … 2-amino-2-(hydroxymethyl)propane-1,3-diol; 5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid …

AT-7519

AT7519 is a selective inhibitor of certain Cyclin Dependent Kinases (CDKs) leading to tumour regression. It is developed by Astex for the treatment of solid tumours and haematological malignancies.
Investigational

Medetomidine

Medetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. Medetomidine is an intravenously available alpha-2 adrenergic agonist. The drug has been developed by Orion Pharma. In the United States, it is currently approved for its veterinary use...
Experimental
Vet approved
Matched Description: … Medetomidine is an intravenously available alpha-2 adrenergic agonist. …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists …

Carlumab

Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …

Simlukafusp alfa

RO6874281 is under investigation in clinical trial NCT03193190 (A Study of Multiple Immunotherapy-based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-pancreatic Cancer)).
Investigational
Matched Synonyms: … Anti-fap/interleukin-2 fusion protein ro6874281 …

Human Umbilical Cord Mesenchymal Stem Cells

Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity. Stem cells from the umbilical cord offer several advantages, including: non-invasive collection procedures, more hearty and steady growth than bone-marrow derived stem cells (they can maintain a steady doubling time (DT) over up to...
Investigational

Dasiprotimut-T

Dasiprotimut-T is a personalized therapeutic vaccine against B-cell lymphomas. It has been investigated in clinical trials.
Investigational
Matched Description: … Dasiprotimut-T is a personalized therapeutic vaccine against B-cell lymphomas. …

Proinsulin human

Investigational

Timolumab

Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational

4-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene]-1,3-Dihydro-Indol-2-One

Experimental
Matched Name: … ]-1,3-Dihydro-Indol-2-One ... 4-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene …
Matched Iupac: … ]-2,3-dihydro-1H-indol-2-one ... (3Z)-4-[(3R,4S,5R)-4-amino-3,5-dihydroxyhex-1-yn-1-yl]-5-fluoro-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene …

2-[({2-[(1Z)-3-(DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID

Experimental
Matched Name: … 2-[({2-[(1Z)-3-(DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE …
Matched Iupac: … 2-{2-[(1Z)-3-(dimethylamino)prop-1-en-1-yl]-4-fluorobenzenesulfonamido}-5,6,7,8-tetrahydronaphthalene …

5-methoxy-N,N-dimethyltryptamine

5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug, as well as dimethyltryptamine and bufotenin, have been registered to be used in South America in religious and spiritual rituals.
Experimental
Illicit
Matched Synonyms: … 3-(2-dimethylaminoethyl)-5-methoxyindole ... 3-[2-(N,N-Dimethylamino)ethyl]-5-methoxy-indole …
Matched Iupac: … [2-(5-methoxy-1H-indol-3-yl)ethyl]dimethylamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Hycanthone

Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.
Experimental
Matched Synonyms: … 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one ... 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one …

Izencitinib

Izencitinib is under investigation in clinical trial NCT03920254 (TD-1473 Long-term Safety (LTS) Ulcerative Colitis (UC) Study).
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Galegenimab

Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration (AMD)).
Investigational

Saruparib

Saruparib is under investigation in clinical trial NCT06380751 (Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in Hr-positive, Her2-negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or Palb2m Advanced Breast Cancer).
Investigational
Matched Synonyms: … 2-Pyridinecarboxamide, 5-[4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3-yl)methyl]-1-piperazinyl]- ... 5-{4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3- yl)methyl]piperazin-1-yl}-N-methylpyridine-2- carboxamide …
Matched Description: … CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in Hr-positive, Her2-negative (IHC 0, 1+, 2+ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Ulodesine

Ulodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint Disease.
Investigational

Phytic acid

Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).
Investigational

Aldumastat

Investigational

Tribulus terrestris fruit

Tribulus terrestris fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental

Etryptamine

In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA approved antidepressant under the name Monase. However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis,...
Illicit
Investigational
Withdrawn
Matched Synonyms: … 3-(2-aminobutyl)indole …
Matched Iupac: … 1-(1H-indol-3-yl)butan-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

WAY-151693

Experimental
Matched Synonyms: … N-Hydroxy-2-{[(4-methoxyphenyl)sulfonyl](3-pyridinylmethyl)amino}-3-methylbenzamide …
Matched Iupac: … N-hydroxy-3-methyl-2-{N-[(pyridin-3-yl)methyl]4-methoxybenzenesulfonamido}benzamide …

Istaroxime

Investigational
Matched Synonyms: … 3-((2-Aminoethoxy)imino)-5alpha-androstan-6,17-dione …
Matched Iupac: … (3aS,3bR,5aS,9aR,9bS,11aS)-7-[(2-aminoethoxy)imino]-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene …

Ellagic acid

Ellagic acid is present in several fruits such as cranberries, strawberries, raspberries, and pomegranates. In pomegranates, there are several therapeutic compounds but ellagic acid is the most active and abundant. Ellagic acid is also present in vegetables. Ellagic acid is an investigational drug studied for treatment of Follicular Lymphoma (phase...
Investigational
Matched Description: … Ellagic acid is an investigational drug studied for treatment of Follicular Lymphoma (phase 2 trial), ... protection from brain injury of intrauterine growth restricted babies (phase 1 and 2 trial), improvement ... of cardiovascular function in adolescents who are obese (phase 2 trial), and topical treatment of solar …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Luminol

Investigational
Displaying drugs 7501 - 7525 of 8211 in total