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Displaying drugs 801 - 825 of 1189 in total

Triethylenetetramine

Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, spermidine and spermine. TETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925. Initially approved by the FDA in 1985...
Approved
Investigational
Matched Description: … Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective ... It is a structural analog of linear polyamine compounds, [spermidine] and [spermine]. ... TETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925 …
Matched Salts name: … Trientine hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Products: … Trientine Hydrochloride ... Trientine hydrochloride …

Bisphenol A diglycidyl ether

Approved
Experimental
Matched Synonyms: … 2,2-Bis(4-glycidyloxyphenyl)propane ... 2,2-bis(4'-glycidyloxyphenyl)propane …
Matched Categories: … Increased Histamine Release …

Liraglutide

Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist.[Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid...
Approved
Matched Synonyms: … N²⁶-(hexadecanoyl-gamma-glutamyle)-[34-arginine]GLP-1-(7-37)-peptide ... N²⁶-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptide …
Matched Description: … Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... for lysine at position 34. ... [Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and liraglutide ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Donepezil

In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and ... with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Salts name: … Donepezil hydrochloride ... Donepezil hydrochloride monohydrate …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … ANDEM 10 MG FILM TABLET, 14 ADET ... ANDEM 10 MG FILM TABLET, 28 ADET ... ANDEM 10 MG FILM TABLET, 56 ADET …

AMY-101

AMY-101, also known as compstatin 40, is a peptidic inhibitor of the central complement component C3. AMY-101 is under investigation in clinical trial NCT03694444 (A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis).
Investigational
Matched Synonyms: … S3,S13-Cyclo(D-tyrolsyl-L-isoleucyl-L-cysteinyl-L-valyl-1-methyl-L-tryptophyl-L-glutaminyl-L-aspartyl-L-tryptophyl-N-methyl-L-glycyl-L-alanyl-L-histidyl-L-arginyl-L-cysteinyl-N-methyl-L-isoleucinamide …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Dobutamine

A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Matched Mixtures name: … Dobutamine Hydrochloride in Dextrose …
Matched Salts name: … Dobutamine hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … Dobutamine Hydrochloride ... DOBUTAMINE HYDROCHLORIDE ... Dobutamine Hydrochloride in Dextrose …

Dinor-N(Omega)-Hydroxy-L-Arginine

Experimental
Matched Name: … Dinor-N(Omega)-Hydroxy-L-Arginine …

N-[Isoleucinyl]-N'-[adenosyl]-diaminosufone

Experimental
Matched Name: … N-[Isoleucinyl]-N'-[adenosyl]-diaminosufone …

Cocaine

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... the eye, ear, nose, and throat. ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Matched Salts name: … Cocaine hydrochloride …
Matched Categories: … Analgesics and Anesthetics …
Matched Products: … Cocaine Hydrochloride ... Cocaine Hydrochloride Nasal ... Cocaine Hydrochloride Top Sol 40mg/ml …

Naloxone

Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Description: … , and even death. ... Frequently also carried by medical and emergency personnel and at events known to be associated with ... life-threatening symptoms such as respiratory depression, reduced heart rate, slurred speech, drowsiness, and …
Matched Mixtures name: … Pentazocine Hydrochloride and Naloxone Hydrochloride ... Pentazocine Hydrochloride and Naloxone Hydrochloride ... Pentazocine and naloxone hydrochlorides …
Matched Salts name: … Naloxone hydrochloride ... Naloxone hydrochloride dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... tilidine and naloxone ... oxycodone and naloxone ... pentazocine and naloxone ... hydromorphone and naloxone …
Matched Products: … Naloxone Hydrochloride ... Naloxone Hydrochloride Fine ... NALOXONE HYDROCHLORIDE …

N-(5'-phosphopyridoxyl)-L-alanine

Experimental
Matched Name: … N-(5'-phosphopyridoxyl)-L-alanine …

N-(3-MERCAPTOPROPANOYL)-D-ALANINE

Experimental
Matched Name: … N-(3-MERCAPTOPROPANOYL)-D-ALANINE …

N-[1H-INDOL-3-YL-ACETYL]VALINE ACID

Experimental
Matched Name: … N-[1H-INDOL-3-YL-ACETYL]VALINE ACID …

Nanvuranlat

Investigational
Matched Synonyms: … L-tyrosine, o-((5-amino-2-phenyl-7-benzoxazolyl)methyl)-3,5-dichloro- ... O-((5-amino-2-phenyl-1,3-benzoxazol-7-yl)methyl)-3,5- dichloro-l-tyrosine …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Ketoprofen

Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Description: … Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and …
Matched Salts name: … Ketoprofen lysine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiinflammatory and Antirheumatic Products ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … KETOPROFEN LYSINE ... Vopac - Ketoprofen, Lidocaine Hydrochloride Pac …

Serinus canaria feather

Canary feather is used in allergenic testing.
Approved
Matched Name: … Serinus canaria feather …
Matched Categories: … Increased Histamine Release …

Fosgemcitabine palabenamide

NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
Investigational
Matched Synonyms: … L-ALANINE, N-(2'-DEOXY-2',2'-DIFLUORO-P-PHENYL-5'-CYTIDYLYL)-, PHENYLMETHYL ESTER ... N-[[P(S)]-2'-deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl]-L-alanine phenylmethyl ester ... L-Alanine, N-[[P(S)]-2'-deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl]-, phenylmethyl ester …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Lemzoparlimab

Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax in Participants With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Immunoglobulin g4(228-proline), anti-(human cd47 antigen) (human monoclonal tj011133 .gamma.4-chain), …
Matched Description: … Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and ... Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and ... Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax …

Xeligekimab

Xeligekimab is under investigation in clinical trial NCT06028490 (A Study of Il4rα Monoclonal Antibody in Patients With Uncontrolled Seasonal Allergic Rhinitis.).
Investigational
Matched Synonyms: … Immunoglobulin g4 (235-proline), anti-(human interleukin 17a) (human monoclonal gr1501 .gamma.4-chain …

Penicillamine

Penicillamine is a pharmaceutical of the chelator class. The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine). It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties.
Approved
Matched Synonyms: … 3-mercapto-D-valine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiinflammatory and Antirheumatic Products ... Penicillamine and Similar Agents …

Sevoflurane

Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996....
Approved
Vet approved
Matched Synonyms: … 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane …
Matched Iupac: … 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane …
Matched Description: … [L42340] It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition ... Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. ... The hemodynamic and respiratory depressive effects of sevoflurane are well tolerated, and most patients …

Sabatolimab

Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline,de-c-terminal-lysine), anti-(human hepatitis virus a cellular receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Monoclonal antibodies and antibody drug conjugates …

CA-074 methyl ester

CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]
Experimental
Matched Synonyms: … Methyl N-({(2s,3s)-3-[(propylamino)carbonyl]oxiran-2-Yl}carbonyl)-L-isoleucyl-L-prolinate ... L-Proline, N-[[(2S,3S)-3-[(propylamino)carbonyl]oxiranyl]carbonyl]-L-isoleucyl-, methyl ester ... L-Proline, 1-[N-[[3-[(propylamino)carbonyl]oxiranyl]carbonyl]-L-isoleucyl]-, methyl ester, (2S-trans) …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Lymecycline

Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Synonyms: … Tetracycline-L-methylene lysine ... 5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamido)methyl)lysine …
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and ... has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and ... It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. …

Anisotropine methylbromide

Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary...
Approved
Matched International brands: … Valpin …
Matched Description: … gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant ... , and accommodation; cause dilatation of the pupil; and increase the heart rate. ... action on the bile ducts and gallbladder. …
Displaying drugs 801 - 825 of 1189 in total