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Displaying drugs 1026 - 1050 of 1156 in total
Experimental
Matched Synonyms: … 3'-Fluoro-3'-deoxythymidine 5'-phosphate
Donanemab is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against insoluble N-truncated pyroglutamate amyloid beta (Aβ), which is found in the brain amyloid plaques that contribute to the pathophysiology of Alzheimer's Disease (AD). On July 2, 2024, donanemab was approved by the FDA for the treatment of AD...
Approved
Investigational
Matched Synonyms: … with human clone LY3002813 κ-chain, dimer ... Immunoglobulin G1, anti-(human pyroglutamyl Aβ (3-x) peptide)(human clone LY3002813 γ1-chain), disulfide …
Matched Description: … [L50988] It works to reduce amyloid beta plaques and impede the progression of AD.[L50988] …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Adnectin, anti-(human growth differentiation factor 8) (synthetic clone prd-1474 fibronectin type iii ... amino acid linker) fusion protein with adnectin, anti-(human growth differentiation factor 8) (human clone
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion …
Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release...
Approved
Matched Description: … increase the number and sensitivity of insulin receptors. ... first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release a proton and ... Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … MELLIDYS MR 30 MG MODIFIYE SALIM TABLET, 90 ADET ... MELLIDYS MR 30 MG MODIFIYE SALIM TABLET, 120 ADET ... MELLIDYS MR 30 MG MODIFIYE SALIM TABLET, 30 ADET …
Experimental
Matched Name: … 4-oxo-nicotinamide-adenine dinucleotide phosphate
Experimental
Matched Name: … PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole …
Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Approved
Investigational
Nutraceutical
Matched International brands: … Sam-Sulfate
Matched Description: … Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all ... It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives ... Amino Acids, Peptides, and Proteins ... Nucleic Acids, Nucleotides, and Nucleosides …
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Approved
Matched Description: … It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes …
Matched Salts name: … Colistin sulfate
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … YH Colistin Sulfate 10% w/w Granule …
Arabica coffee bean allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Coffea vulgaris seed …
Experimental
Matched Name: … D-Glycero-D-Mannopyranose-7-Phosphate
1-Deoxy-D-xylulose 5-phosphate is a solid. This compound belongs to the pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. The proteins that 1-Deoxy-D-xylulose 5-phosphate targets include 1-Deoxy-D-xylulose 5-phosphate reductoisomerase and pyridoxine 5'-phosphate synthase. 1-Deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway.
Experimental
Matched Name: … 1-Deoxy-D-xylulose 5-phosphate
Matched Description: … and pyridoxine 5'-phosphate synthase. 1-Deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate ... 1-Deoxy-D-xylulose 5-phosphate is a solid. This compound belongs to the pentose phosphates. ... The proteins that 1-Deoxy-D-xylulose 5-phosphate targets include 1-Deoxy-D-xylulose 5-phosphate reductoisomerase …
Matched Categories: … Sugar Phosphates
Experimental
Matched Name: … N-acetyl-D-glucosamine-6-phosphate
Experimental
Matched Name: … Nicotinamide 8-bromo-adenine dinucleotide phosphate
Experimental
Matched Name: … N(6)-(pyridoxal phosphate)-L-lysine …
Experimental
Matched Name: … N-Pyridoxyl-2-Methylalanine-5-Phosphate
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Description: … changes, and synovial membrane inflammation. ... Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin ... Glucosamine Sulfate, Chondroitin Sulfate, Ibuprofen …
Matched Salts name: … Glucosamine sulfate ... Glucosamine sulfate sodium chloride ... Glucosamine sulfate potassium chloride …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … GNC Glucosamine Sulfate 500 ... GNC Glucosamine Sulfate 1000 Tablet ... Osteosave Granules (Glucosamine Sulfate Granules 1.5 g) …
An irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically. (From Martindale, The Extra Pharmacopoeia, 29th ed, p1330)
Approved
Investigational
Withdrawn
Matched Synonyms: … Fluorodiisopropyl phosphate
Matched Description: … Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically …
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Description: … /or the D2 receptor gene that may be at least partly overcome by the dopaminergic effects of methylphenidate ... the most effective and widely used treatment for ADHD, and are considered first-line options for children ... system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and
Matched Categories: … Methylphenidate and isomer ... Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … CONCERTA 18 MG KONTROLLÜ SALIM TABLETİ, 30 ADET ... CONCERTA 27 MG KONTROLLÜ SALIM TABLETİ, 30 ADET ... CONCERTA 36 MG KONTROLLÜ SALIM TABLETİ, 30 ADET …
Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).
Investigational
Matched Synonyms: … nvs260714 .gamma.4-chain), disulfide with human-mus musculus monoclonal clone nvs260714 .kappa. ... de-c-terminal-lysine), anti-(human hepatitis virus a cellular receptor 2) (human-mus musculus monoclonal clone
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Monoclonal antibodies and antibody drug conjugates …
Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Description: … The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon ... Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise …
Matched Mixtures name: … Reddy-sitagliptin and Metformin Hydrochloride ... Reddy-sitagliptin and Metformin Hydrochloride ... Reddy-sitagliptin and Metformin Hydrochloride …
Matched Salts name: … Sitagliptin phosphate
Matched Categories: … Alimentary Tract and Metabolism ... sitagliptin and simvastatin ... metformin and sitagliptin ... sitagliptin and ertugliflozin ... sitagliptin and dapagliflozin …
Matched Products: … SITAGLIPTIN PHOSPHATE MONOHYDRATE …
Experimental
Matched Name: … N-Octyl-2-Hydroxyethyl Sulfoxide
Experimental
Matched Name: … Decyl(dimethyl)phosphine oxide …
Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated levels of prolactin or hyperprolactinaemia. Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido, as well as long-term complications such as osteoporosis . Newer dopamine receptor agonists such as quinagolide and DB00248 are...
Approved
Investigational
Matched Synonyms: … N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin-3-yl)sulfamide
Matched Description: … These drugs are effective in patients who are intolerant or resistant to [DB01200]. ... Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido ... Newer dopamine receptor agonists such as quinagolide and [DB00248] are shown to effectively inhibit prolactin …
Matched Categories: … Genito Urinary System and Sex Hormones …
Approved
Matched Synonyms: … Diphtheria toxin mutant CRM197 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 1026 - 1050 of 1156 in total