Displaying drugs 1076 - 1100 of 1624 in total
Recombinant human CD4 immunoglobulin G
Investigational
Matched Synonyms: … Recombinant human CD4 immunoglobulin G …
Matched Name: … Recombinant human CD4 immunoglobulin G …
Matched Name: … Recombinant human CD4 immunoglobulin G …
Ligufalimab
Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47. It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Immunoglobulin g4 (225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal ak117 .gamma ... .4-chain), disulfide with human-mus musculus monoclonal ak117 .kappa. …
Bepranemab
Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline), anti-(human tau protein) (human-rattus norvegicus monoclonal ucb0107 ... .gamma.4-chain), disulfide with human-rattus norvegicus monoclonal ucb0107 .kappa. …
Matched Description: … Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau. …
Matched Description: … Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau. …
Efineptakin alfa
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Recombinant human IL-7-HYFC ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease ... Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease ... Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Asunercept
Asunercept is under investigation in clinical trial NCT02853565 (A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme).
Investigational
Matched Synonyms: … FAS ANTIGEN (HUMAN EXTRACELLULAR DOMAIN FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ontorpacept
Investigational
Matched Synonyms: … (human) fusion protein with immunoglobulin g1 (human fc fragment), dimer …
Apitegromab
Apitegromab is under investigation in clinical trial NCT03921528 (An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy).
Investigational
Matched Synonyms: … Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk ... -015 .gamma.4-chain), disulfide with human monoclonal srk-015 .lambda. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Briquilimab
Briquilimab is a humanized aglycosylated IgG1 kappa monoclonal antibody targeting CD117 (cKit).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (297-GLUTAMINE), ANTI-(HUMAN C-KIT RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JSP191 ... .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .KAPPA. …
Litifilimab
Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and Safety of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory And/or Intolerant to Antimalarial Therapy).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human blood dendritic cell antigen 2) (human-mus musculus monoclonal biib059 ... .gamma.1-chain), disulfide with human-mus musculus monoclonal biib059 .kappa. …
Matched Description: … Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and ... And/or Intolerant to Antimalarial Therapy). ... of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And …
Matched Description: … Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and ... And/or Intolerant to Antimalarial Therapy). ... of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And …
Sotevtamab
Sotevtamab is under investigation in clinical trial NCT06225843 (Sotevtamab (AB-16B5) Combined With FOLFOX as Neoadjuvant Treatment Prior to Resection of Colorectal Cancer Liver Metastasis).
Investigational
Matched Synonyms: … -chain) (human-mus musculus monoclonal ab-16b5 .gamma.2-chain), disulfide with human-mus musculus monoclonal ... Immunoglobulin g2, anti-(human clusterin .beta. …
Olinvacimab
Olinvacimab is under investigation in clinical trial NCT03033524 (Trial to Evaluate the Safety of Ttac-0001(tanibirumab) in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ttac- ... Fully human monoclonal antibody targets vascular endothelial growth factor receptor 2 ... 0001 heavy chain), disulfide with human monoclonal ttac-0001 light chain, dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Interleukin-1 alpha, human recombinant
Experimental
Matched Name: … Interleukin-1 alpha, human recombinant …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Recombinant human type VII collagen
Investigational
Matched Name: … Recombinant human type VII collagen …
Human umbilical tissue derived cells
Investigational
Matched Name: … Human umbilical tissue derived cells …
Lumiliximab
Lumiliximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE antibody, for the potential treatment of allergic conditions. Lumiliximab was developed by IDEC Pharmaceuticals, which was acquired by Biogen. Clinical trials for...
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC- ... IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC- ... 152 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .KAPPA. …
Matched Description: … Clinical trials for CLL were terminated in 2010, and for allergic asthma in 2007. ... It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Clinical trials for CLL were terminated in 2010, and for allergic asthma in 2007. ... It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ulenistamab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human pancreatic adenocarcinoma up-regulated factor) (human-mus musculus monoclonal ... pbp1510 .gamma.1-chain), disulfide with human-mus musculus monoclonal pbp1510 .kappa. …
Rosnilimab
Rosnilimab is under investigation in clinical trial NCT06041269 (A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human programmed cell death protein 1) (human-mus musculus monoclonal anb030 ... .gamma.1-chain), disulfide with human-mus musculus monoclonal anb030 .kappa. …
Matched Description: … Rosnilimab is under investigation in clinical trial NCT06041269 (A Study of Efficacy and Safety of Rosnilimab …
Matched Description: … Rosnilimab is under investigation in clinical trial NCT06041269 (A Study of Efficacy and Safety of Rosnilimab …
Frexalimab
Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis).
Investigational
Matched Synonyms: … Immunoglobulin G1 (272-arginine,325-alanine), anti-(human CD40 ligand) (human-mus musculus monoclonal ... SAR441344 gamma1-chain), disulfide with human-mus musculus monoclonal SAR441344 kappa-chain, dimer …
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
CPI-006
CPI-006 was investigated in clinical trials NCT03454451, NCT04464395, and NCT04734873 to evaluate its safety and efficacy. NCT03454451 focused on advanced cancers (e.g., non-small cell lung cancer, renal cell cancer, colorectal cancer). NCT04464395 and NCT04734873 assessed its use for hospitalized COVID-19 patients alone or with standard care.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (302-GLUTAMINE), ANTI-(HUMAN 5'-NUCLEOTIDASE) (HUMAN-MUS MUSCULUS MONOCLONAL CPI-006 ... .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS-MUSCULUS MONOCLONAL CPI-006 .KAPPA. …
Matched Description: … safety and efficacy. ... CPI-006 was investigated in clinical trials NCT03454451, NCT04464395, and NCT04734873 to evaluate its ... NCT04464395 and NCT04734873 assessed its use for hospitalized COVID-19 patients alone or with standard …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … safety and efficacy. ... CPI-006 was investigated in clinical trials NCT03454451, NCT04464395, and NCT04734873 to evaluate its ... NCT04464395 and NCT04734873 assessed its use for hospitalized COVID-19 patients alone or with standard …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion ... protein with human tumor necrosis factor .alpha., trimer …
EDI-200
EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.
Investigational
Matched Synonyms: … HUMAN IMMUNOGLOBULIN G1 CONSTANT REGION - HUMAN ECTODYSPLASIN-A1 RECEPTOR-BINDING DOMAIN FUSION PROTEIN …
Matched Description: … human receptor binding domain of ectodysplasin-A1. ... EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … human receptor binding domain of ectodysplasin-A1. ... EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Timolumab
Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion …
Matched Description: … Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tagitanlimab
Investigational
Matched Synonyms: … Immunoglobulin g1 (237-alanine,238-alanine,240-alanine), anti-(human programmed death-ligand 1) (human ... monoclonal kla167 .gamma.1-chain), disulfide with human monoclonal kla167 .kappa. …
Amlitelimab
Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).
Investigational
Matched Synonyms: … Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005- ... 2d10 .gamma.4-chain), disulfide with human monoclonal ky1005-2d10 .kappa. …
Matched Description: … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and ... Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and …
Matched Description: … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and ... Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and …
Vixarelimab
Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis).
Investigational
Matched Synonyms: … (human monoclonal kpl-716 .gamma.-chain), disulfide with human monoclonal kpl-716 .lambda. ... Immunoglobulin g (234-proline,303-glutamine), anti-(human oncostatin m receptor subunit .beta.) …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Displaying drugs 1076 - 1100 of 1624 in total