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Displaying drugs 1126 - 1150 of 1214 in total
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Synonyms: … 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
Matched Description: … Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels ... [A255647] Diazoxide also exhibits hypotensive activity and reduces arteriolar smooth muscle and vascular ... and electrolyte disturbances. …
Matched Categories: … Potassium Channel Opener …
Experimental
Matched Synonyms: … Fluourine-18 Fluoromethylcholine …
Matched Salts name: … Fluorocholine chloride F-18 …
Matched Categories: … Fluorine Radioisotopes …
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … This disease has been well-documented in historical medical records and appears in the biographies of ... enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and ... It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [ …
Matched Salts name: … Allopurinol sodium
Matched Products: … Allopurinol sodium
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Synonyms: … 6-trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... ±-3-benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... bendroflumethiazide and potassium ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... bendroflumethiazide and potassium-sparing agents ... Genito Urinary System and Sex Hormones …
Experimental
Matched Name: … Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate
Investigational
Matched Synonyms: … ][1,9,2,5,17]dithiatriazacyclotricosin-19-one, 17-fluoro-20,21-dihydro-10-methoxy-29-methyl-, 13,13-dioxide
Experimental
Matched Categories: … Benzamides and benzamide derivatives …
Matched Products: … LEVOSULPIRIDE FERRER
An antiferromagnetic material; constitutes the core of natural ferritin.
Experimental
Matched Synonyms: … Hydrated ferric oxide …
Matched Name: … Ferric oxyhydroxide …
Matched Categories: … Phosphate Binder ... Phosphate Chelating Activity …
Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Approved
Investigational
Matched Description: … Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload …
Matched Products: … FEROUT 90 MG FİLM KAPLI TABLET, 30 ADET ... FEROUT 360 MG FİLM KAPLI TABLET, 30 ADET ... FEROUT 180 MG FİLM KAPLI TABLET, 30 ADET …
Experimental
Matched Name: … 4-(2-Aminoethyl)Benzenesulfonyl Fluoride
Matched Iupac: … 4-(2-aminoethyl)benzene-1-sulfonyl fluoride
Lactide, L- is under investigation in clinical trial NCT05450471 (Effectiveness of Endonasal Polymeric Implant for Chronic Rhinosinusitis).
Investigational
Matched Synonyms: … P-dioxane-2,5-dione, 3,6-dimethyl-, l- ... 1,4-dioxane-2,5-dione, 3,6-dimethyl-, (3s-cis)- ... 1,4-dioxane-2,5-dione, 3,6-dimethyl-, (3s,5s)- …
Silibinin is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin and others. Silibinin is presented as a mixture of two diastereomers, silybin A and silybin B, which are found in an approximately equimolar...
Experimental
Investigational
Matched Description: … both small and nonsmall human lung carcinoma cells. ... containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin and ... Silibinin is presented as a mixture of two diastereomers, silybin A and silybin B, which are found in …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy …
Matched Products: … SILIBION CAPSULAS …
Ferric maltol is an iron(III) atom complexed with 3 maltol molecules to increase the bioavailability compared to iron(II), without depositing it in the duodenum as insoluble ferric hydroxide and phosphate. Ferric maltol has been described in literature since at least the late 1980s as a potential treatment for iron deficiency....
Approved
Matched Synonyms: … Ferric maltol …
Matched Name: … Ferric maltol …
Matched Description: … compared to iron(II), without depositing it in the duodenum as insoluble ferric hydroxide and phosphate ... [A189291] Ferric maltol was granted FDA Approval on 25 July 2019.[L10974] ... Ferric maltol is an iron(III) atom complexed with 3 maltol molecules to increase the bioavailability …
Matched Categories: … Blood and Blood Forming Organs ... ferric maltol …
Experimental
Matched Name: … 3,4-Dihydroxy-5-(4-oxo-4,5-dihydro-1H-pyrrolo[3,2-d]pyrimidin-7-yl)-2-pyrrolidinyl]methyl dihydrogen phosphate
Experimental
Matched Name: … Ferric hydroxide …
Matched Categories: … Blood and Blood Forming Organs ... ferric hydroxide …
Approved
Matched Synonyms: … Ferrous cevitamate …
Matched Name: … Ferrous ascorbate …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition ... ferrous ascorbate …
Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.
Approved
Matched Synonyms: … Ferric carboxymaltose …
Matched Name: … Ferric carboxymaltose …
Matched Description: … Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. …
Approved
Matched Synonyms: … Ferrous cysteine glycinate chelate (1:2:1) …
Matched Name: … Ferrous cysteine glycinate …
Experimental
Matched Synonyms: … (6S)-4-Benzyl-6-(1-methyl-2,2-dioxido-1,3-dihydro-2,1-benzothiazol-5-yl)-3-morpholinone …
MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Investigational
Matched Synonyms: … 1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxide
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators …
Ferric pyrophosphate is an iron replacement product. Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma. The ferric ion is strongly complexed by pyrophosphate. It presents an increasing interest as this insoluble...
Experimental
Matched Name: … Ferric pyrophosphate …
Matched Iupac: … tetrairon(3+) tri(phosphonatooxy)phosphonate
Matched Description: … Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation ... presents an increasing interest as this insoluble form can be milder in the gastrointestinal tract and ... Ferric pyrophosphate is an iron replacement product. …
Matched Categories: … Phosphate salts ... Phosphoric Acids …
Experimental
Matched Name: … Ferrous tartrate …
Matched Categories: … Blood and Blood Forming Organs ... ferrous tartrate …
Experimental
Matched Name: … Ferrous carbonate …
Matched Categories: … Blood and Blood Forming Organs ... ferrous carbonate …
Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to the compound florbetapir, a molecule that binds with high affinity to beta amyloid plaque, a peptide that plays a key role in Alzheimer's Disease pathogenesis. Marketed as the product Amyvid, florbetapir 18F is indicated for positron emission tomography...
Approved
Investigational
Matched Synonyms: … florbetapir-fluorine-18 …
Matched Description: … density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and ... Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to ... The radionucleide fluorine-18 was chosen as it has a half life of 110 minutes allowing it to accumulate …
Matched Categories: … Fluorine Radioisotopes …
Experimental
Matched Name: … 1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE
Displaying drugs 1126 - 1150 of 1214 in total