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Displaying drugs 1226 - 1250 of 1482 in total
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Description: … aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding ... statistically significant decreases in urinary albumin and protein excretion in patients diagnosed with …
Matched Mixtures name: … Valsartan and Hydrochlorothiazide ... Valsartan and Hydrochlorothiazide ... Valsartan and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics ... Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... valsartan and nebivolol ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Products: … DIOVAN 160MG PROTECT ... DIOVAN 160MG PROTECT FTA ... DIOVAN 160 MG PROTECT FTA …
Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup W-135. The vaccine contains N. meningitis serogroup W-135 capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Synonyms: … Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine …
Matched Description: … vaccine contains *N. meningitis* serogroup W-135 capsular polysaccharide antigens that are purified and ... individually conjugated to diphtheria toxoid protein that are extracted from *Corynebacterium diphtheriae …
Investigational
Matched Synonyms: … A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7 …
Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Sodium 3-(3-tert-butyl-4-methoxy-5-{6­ [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6 …
Matched Description: … categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... [DB00503] for genotype 1b and with [DB00811] for genotype 1a of Hepatitis C [L852]. ... Dasabuvir is a non-nucleoside NS5B inhibitor which binds to the palm domain of NS5B and induces a conformational …
Matched Salts name: … Dasabuvir sodium ... Dasabuvir sodium monohydrate …
Matched Categories: … dasabuvir, ombitasvir, paritaprevir and ritonavir …
Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 4 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Investigational
Matched Synonyms: … Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated ... then conjugated to the protein carrier CRM197 to form the glycoconjugate. …
Matched Mixtures name: … PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR ... PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR, 10 ADET ... PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR, 50 ADET …
Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 6b individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Synonyms: … Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated ... then conjugated to the protein carrier CRM197 to form the glycoconjugate. …
Matched Mixtures name: … PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR ... PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR, 10 ADET ... PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR, 50 ADET …
Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 1 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Synonyms: … Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated ... then conjugated to the protein carrier CRM197 to form the glycoconjugate. ... Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is …
Matched Mixtures name: … PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR ... PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR, 10 ADET ... PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR, 50 ADET …
Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 5 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Synonyms: … Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated ... then conjugated to the protein carrier CRM197 to form the glycoconjugate. ... Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is …
Matched Mixtures name: … PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR ... PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR, 10 ADET ... PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR, 50 ADET …
Investigational
Matched Synonyms: … Folate binding protein J65 …
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Somatotropin (human) fusion protein with immunoglobulin (synthetic hybrid fc fragment hyfc) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Recombinant Proteins
QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational
Matched Synonyms: … Masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon …
Matched Description: … It binds the CD138 protein on the surface of the tumour cells. ... QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused …
Investigational
Matched Synonyms: … Anti-b1 antibody I-131 ... Iodine-131 anti-b1 antibody
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Approved
Vet approved
Matched Products: … ADVANTAN MILCH ... Advantan Milch 0,1% Emulsion zur Anwendung auf der Haut …
Tagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in Escherichia coli.[A253762, A253887, L43702] Tagraxofusp received its first global approval by the FDA on December 21, 2018...
Approved
Investigational
Matched Synonyms: … Diphtheria toxin-il-3 fusion protein targeting IL-3 receptor …
Matched Description: … and translocation domains of truncated diphtheria toxin (DT) produced in _Escherichia coli_. ... It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins ... Recombinant Proteins ... Recombinant Fusion Proteins
Rozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies to replace existing anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and the prevention of Hemolytic Disease of Newborns (HDN).
Investigational
Matched Synonyms: … Recombinant human antigen-specific polyclonal antibody (pAb) against RhD antigen expressed in Chinese …
Matched Description: … anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and ... Rozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Interleukin-8 is under investigation in clinical trial NCT05148234 (BMS-986253 in Myelodysplastic Syndromes).
Investigational
Matched Synonyms: … NEUTROPHIL-ACTIVATING PROTEIN 1 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Blood Proteins
GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Matched Synonyms: … recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Investigational
Matched Synonyms: … Vasoactive intestinal peptide (VIP)-elastin-like peptide (ELP) fusion protein
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Membrane Proteins ... Protein Precursors …
Giloralimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination With IV Modified FOLFIRINOX (Mffx) With or Without IV Budigalimab Compared to Mffx in Adult Participants With Untreated Pancreatic Cancer Metastasis).
Investigational
Matched Synonyms: … Agonistic anti-cd40 monoclonal antibody abbv-927 ... Anti-cd40 agonist monoclonal antibody abbv-927 …
Matched Description: … Giloralimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and
Investigational
Matched Synonyms: … WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSILON. ... CLAUDIN 18.2) (HUMAN MONOCLONAL HWZV_KLA_L SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN
Investigational
Matched Synonyms: … WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSILON. ... MUCIN 17) (HUMAN MONOCLONAL MUC17_CD3_ALT2 SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN
According to Zymeworks, "ZW25 is a bispecific antibody that can simultaneously bind two non-overlapping epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and removal of HER2 protein from the cell surface, and potent effector function. These combined mechanisms of action have led to...
Investigational
Matched Synonyms: … ANTI-HER2 BI-SPECIFIC MONOCLONAL ANTIBODY ZW25 ... TYROSINEPROTEIN KINASE ERBB-2, EGFR2, HER2, HER-2, P185C-ERBB2, NEU, CD340)), HUMANIZED MONOCLONAL ANTIBODY
Matched Description: … removal of HER2 protein from the cell surface, and potent effector function. ... epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and ... combined mechanisms of action have led to significant anti-tumor activity in preclinical models of breast and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Investigational
Matched Synonyms: … Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Investigational
Matched Synonyms: … immunoglobulin G1 (IgG1)-based, B-cell maturation antigen (BCMA) x CD3 T-cell bispecific monoclonal antibody
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response ... synthetase fused to the FC region of a human antibody. ... Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA …
Displaying drugs 1226 - 1250 of 1482 in total