Displaying drugs 1276 - 1300 of 1482 in total
Evalstotug
Evalstotug is under investigation in clinical trial NCT05271604 (A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck).
Investigational
Matched Synonyms: … 4, CD152)], monoclonal antibody ... Immunoglobulin G1-kappa, anti-[Homo sapiens CTLA4 (cytotoxic T-lymphocyte associated protein 4, CTLA- ... Immunoglobulin G1 [de-448-lysine], anti-(human cytotoxic T-lymphocyte-associated protein 4) (human monoclonal …
Matched Description: … Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and …
Matched Description: … Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and …
Brentuximab vedotin
Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Synonyms: … Monoclonal antibody SGN-30 …
Matched Description: … antibody with the drug monomethyl auristatin E (MMAE). ... It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell ... was revised with a boxed warning of a condition known as progressive multifocal leukoencephalopathy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Monoclonal antibodies and antibody drug conjugates ... Antineoplastic and Immunomodulating Agents ... Proteins ... Blood Proteins …
Matched Description: … antibody with the drug monomethyl auristatin E (MMAE). ... It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell ... was revised with a boxed warning of a condition known as progressive multifocal leukoencephalopathy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Monoclonal antibodies and antibody drug conjugates ... Antineoplastic and Immunomodulating Agents ... Proteins ... Blood Proteins …
Imalumab
Imalumab is under investigation in clinical trial NCT02540356 (Phase 1/2a Two-arm Dose-escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer).
Investigational
Matched Synonyms: … migration inhibitory factor, glycosylation-inhibiting factor, glif, gif)), homo sapiens monoclonal antibody …
Vilastobart
Vilastobart is under investigation in clinical trial NCT04896697 (Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors).
Investigational
Matched Synonyms: … 4, CTLA-4, CD152)], humanized monoclonal antibody ... immunoglobulin G1-fused prodomain kappa, anti-[Homo sapiens CTLA4 (cytotoxic T-lymphocyte associated protein …
Matched Description: … Vilastobart is under investigation in clinical trial NCT04896697 (Vilastobart (XTX101) Monotherapy and ... Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors). …
Matched Description: … Vilastobart is under investigation in clinical trial NCT04896697 (Vilastobart (XTX101) Monotherapy and ... Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors). …
Sirexatamab
Investigational
Matched Synonyms: … Anti-dkk-1 monoclonal antibody ly2812176 ... Dkk1-neutralizing monoclonal antibody dkn-01 …
Letolizumab
Letolizumab is under investigation in clinical trial NCT02273960 (Study to Evaluate Safety and Efficacy in Adult Subjects With ITP).
Investigational
Matched Synonyms: … Immunoglobulin (synthetic light chain variable region fragment) fusion protein with immunoglobulin g …
Matched Description: … Letolizumab is under investigation in clinical trial NCT02273960 (Study to Evaluate Safety and Efficacy …
Matched Description: … Letolizumab is under investigation in clinical trial NCT02273960 (Study to Evaluate Safety and Efficacy …
Efineptakin alfa
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease ... Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Recombinant Proteins …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease ... Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Recombinant Proteins …
VidPrevtyn Beta
VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and Sanofi Pasteur. It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant DNA technology using a baculovirus expression system in an insect cell line that is
derived from Sf9 cells of the fall...
Approved
Investigational
Matched Synonyms: … SARS-CoV-2 prefusion Spike delta TM protein, recombinant (B.1.351 strain) …
Matched Description: … Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and ... [L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant …
Matched Description: … Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and ... [L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant …
AGIL-FA
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype 5 carrying the gene for the human frataxin protein …
Fosfomycin
Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and is produced by Streptomyces fradiae.[A229338,A230348] It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. In terms of...
Approved
Matched Description: … Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and ... group and an epoxide ring. ... [A229338,A230348] It may also be produced synthetically and is commercially available as the disodium …
Matched Salts name: … Fosfomycin sodium …
Matched Products: … FOSFOMYCIN SODIUM …
Matched Salts name: … Fosfomycin sodium …
Matched Products: … FOSFOMYCIN SODIUM …
Asunercept
Asunercept is under investigation in clinical trial NCT02853565 (A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme).
Investigational
Matched Synonyms: … FAS ANTIGEN (HUMAN EXTRACELLULAR DOMAIN FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Membrane Proteins ... Recombinant Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Membrane Proteins ... Recombinant Proteins …
Anti-CD4 CAR T-cell therapy
Investigational
Matched Synonyms: … chimeric antigen receptor directed against the target protein CD4 lentivirally transfected T cells …
Veligrotug
Veligrotug is under investigation in clinical trial NCT00791544 (Dose Finding Study of AVE1642 in Patients With Advanced or Metastatic Liver Carcinoma).
Investigational
Matched Synonyms: … Anti-cd122 monoclonal antibody ave1642 ... Anti-igf-1r monoclonal antibody ave1642 ... sapiens IGF1R (insulin-like growth factor 1 receptor, IGF1-R, IGF-1R, CD221)], chimeric monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Minnelide
Investigational
Matched Synonyms: … -one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium …
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched International brands: … Reskuin …
Matched Description: … [L11638] Levofloxacin, along with other quinolones such as [gatifloxacin] and [moxifloxacin], is a member ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances ... Medications that reduce magnesium levels ... lansoprazole, amoxicillin and levofloxacin …
Matched Description: … [L11638] Levofloxacin, along with other quinolones such as [gatifloxacin] and [moxifloxacin], is a member ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances ... Medications that reduce magnesium levels ... lansoprazole, amoxicillin and levofloxacin …
Tanfanercept
Tanfanercept is under investigation in clinical trial NCT06400589 (A Study to Evaluate the Efficacy and Safety of Tanfanercept (HL036) in Dry Eye Disease).
Investigational
Matched Synonyms: … L-methionyl-(l28>v,s52>m,h55>f,r57>p,h58>g,k121>n) tumor necrosis factor (tnf) binding protein variant ... 1 (tbp-1) with c-terminal extension by further 10 residues of the pro-protein, human, unglycosylated …
Matched Description: … Tanfanercept is under investigation in clinical trial NCT06400589 (A Study to Evaluate the Efficacy and …
Matched Description: … Tanfanercept is under investigation in clinical trial NCT06400589 (A Study to Evaluate the Efficacy and …
Efungumab
Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(candida heat-shock protein hsp 90) (human monoclonal hsp90mab fragment) …
Matched Description: … Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... HSP90 Heat-Shock Proteins …
Matched Description: … Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... HSP90 Heat-Shock Proteins …
Anti-CD5 CAR T-cell therapy
Investigational
Matched Synonyms: … chimeric antigen receptor (CAR) directed against the target protein CD5 …
Timolumab
Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein …
Matched Description: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
STM-217
Investigational
Matched Synonyms: … Soluble receptor fused to part of an antibody that is designed to block the growth factor activin a …
FB-825
FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound IgE (mIgE), causing a depletion of mIgE positive B-cells. It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin E syndrome (HIES).[A258448,L45743]
Investigational
Matched Synonyms: … Recombinant humanized immunoglobulin gamma 1 monoclonal antibody (mAb) directed against the CemX segment …
Matched Description: … It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin ... FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound …
Matched Description: … It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin ... FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound …
Bersanlimab
Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational
Matched Synonyms: … Anti-icam-1 monoclonal antibody bi-505 ... lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), human monoclonal antibody …
Matched Description: … Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule …
Matched Description: … Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule …
Tuparstobart
Tuparstobart is under investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-line Treatment in Participants With Pd-l1-positive (CPS ≥ 1) Recurrent/metastatic Squamous Cell Carcinoma of the Head and Neck).
Investigational
Matched Synonyms: … Anti-LAG-3 Monoclonal Antibody INCAGN02385 ... Immunoglobulin G1 [301-alanine,de-C-terminal-lysine], anti-(human lymphocyte activation gene-3 protein ... [Homo sapiens LAG3 (lymphocyte activating 3, lymphocyte-activation 3, CD223)], humanized monoclonal antibody …
Matched Description: … investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and ... Participants With Pd-l1-positive (CPS ≥ 1) Recurrent/metastatic Squamous Cell Carcinoma of the Head and …
Matched Description: … investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and ... Participants With Pd-l1-positive (CPS ≥ 1) Recurrent/metastatic Squamous Cell Carcinoma of the Head and …
Piperacillin
Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Approved
Matched Mixtures name: … PIPERACILLIN SODIUM and TAZOBACTAM SODIUM ... PIPERACILLIN SODIUM and TAZOBACTAM SODIUM ... PIPERACILLIN SODIUM and TAZOBACTAM SODIUM …
Matched Salts name: … Piperacillin sodium …
Matched Products: … PIPERACILLINA SODICA …
Matched Salts name: … Piperacillin sodium …
Matched Products: … PIPERACILLINA SODICA …
Izokibep
Izokibep is under investigation in clinical trial NCT05623345 (Psoriatic Arthritis Study of Izokibep).
Investigational
Matched Synonyms: … FUSION PROTEIN COMPOSED OF 3 BINDING DOMAINS CONSISTING OF THREE-ALPHA-HELIX MOTIFS, EACH DERIVED FROM ... THE IMMUNOGLOBULIN (IG)-BINDING Z-DOMAIN OF STAPHYLOCOCCAL PROTEIN A (SPA), ENGINEERED FOR BINDING TO …
Displaying drugs 1276 - 1300 of 1482 in total