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Displaying drugs 126 - 150 of 14767 in total
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Description: … and superficial fungal infections in a variety of tissues. ... This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. ... The side effect profile of this drug is minimal. …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … Imidazole and Triazole Derivatives ... Triazole and tetrazole derivatives ... azithromycin, fluconazole and secnidazole ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Phenyltoloxamine is an antihistamine drug with sedative and analgesic effects. It is a H1 receptor blocker and a member of the ethanolamine class of antihistaminergic drugs. It is available in combination products that also contain other analgesics and antitussives such as acetaminophen. Phenyltoloxamine citrate is the more common salt form...
Approved
Matched Description: … It is available in combination products that also contain other analgesics and antitussives such as acetaminophen ... Phenyltoloxamine acts as an adjuvant analgesic, which augments the analgesic effect of acetaminophen. ... It is a H1 receptor blocker and a member of the ethanolamine class of antihistaminergic drugs. …
Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only...
Approved
Investigational
Matched Description: … It is composed of 2 heavy chains, each containing 456 amino acids, and 2 light chains of the lambda subclass ... Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the ... , each containing 216 amino acids, with an approximate molecular weight of 150 kDa [FDA Label]. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Sotrovimab (VIR-7831), also known as GSK4182136, is a monoclonal antibody that can neutralize the SARS-CoV-2 virus. Sotrovimab was initially been granted emergency use authorization (EUA) to treat mild-to-moderate COVID-19 on May 26, 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of...
Approved
Investigational
Matched Description: … 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral ... [A7045, A231769] It has also been misused for non-therapeutic purposes as a causative drug for several ... cases of drug-facilitated sexual assault. …
Matched Mixtures name: … Up and Up Ultra Itchy Relief ... Redness reliever and Lubricant ... Seasonal itchy and Red eye relief …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Foster and Thrive Original Formula Eye Drops ... Walgreens Eye Drops Original 15mL and twin pack …
Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Description: … of common colds and with decreased symptom severity. ... salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for ... It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration …
Matched Mixtures name: … One A Day With Non-medicinal Echinacea ... Multivitamin and Mineral ... Zinc and Algin Tab Nu Life …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Alimentary Tract and Metabolism …
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Men's Biomultiple Vitamin and Mineral Supplement …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Description: … (L) form may antagonize the effects of the dextrorotatory isomer. ... Small quantities of pantothenic acid are found in nearly every food, with high amounts in whole-grain ... Only the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory …
Matched Mixtures name: … Herbs of Gold B Complex Plus Softgel ... Harvest Of Values All B Complex Tab ... B Complex W Vit C W Non-med Yeast&liver Tab …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Nutmeg allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... Non-Standardized Food Allergenic Extract ... Non-Standardized Plant Allergenic Extract …
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from lactose. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. sucrose). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides...
Approved
Investigational
Matched Description: … non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in patients ... [A190918] It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet ... [A190912] Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …
Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … Without treatment or improvement in non-pharmacological measures such as diet and exercise to lower blood ... Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin ... is a slowly progressing metabolic disorder caused by a combination of genetic and lifestyle factors …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and insulin aspart ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … .Insulin Aspart Protamine and Insulin Aspart ... Insulin Aspart Protamine and Insulin Aspart Mix 70/30 …
Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Description: … Bacitracin is a combination of at least 9 bacitracins. ... [A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. ... bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Up and Up First Aid Antibiotic ... Up and Up Bacitracin first aid …
Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Description: … [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Description: … 25% of the mixture. ... Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up …
Matched Categories: … Alpha and Beta Blocking Agents and Thiazides ... labetalol and thiazides ... Alpha and Beta Blocking Agents ... labetalol and other diuretics ... Beta Blocking Agents and Thiazides …
Matched Products: … BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) …
Gaxilose has been used in trials studying the diagnostic of Lactose Intolerance.
Approved
Investigational
Matched Description: … Gaxilose has been used in trials studying the diagnostic of Lactose Intolerance. …
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the...
Approved
Matched Description: … strength and frequency of contractions and decrease cervical tone. ... Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages ... [L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... naproxen and misoprostol ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Antiinflammatory and Antirheumatic Products …
Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... coagulation enzymes thrombin (factor IIa) and factor Xa. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sod and 0.9% Sod Chloride Inj ... Heparin Sodium and Dextrose 5% Inj USP …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium and Sodium Chloride …
A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Approved
Investigational
Matched Description: … The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic …
Matched Categories: … acebutolol and thiazides ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Selective, and Thiazides …
Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Description: … [A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting ... [A185138] It is indicated to treat edema and hypertension. ... [A185138] Many combination products are available containing hydrochlorothiazide and angiotensin converting …
Matched Mixtures name: … Lisinopril and HCTZ ... Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide …
Matched Categories: … combinations of sulfonamides ... Non Potassium Sparing Diuretics ... hydrochlorothiazide and potassium ... aliskiren and hydrochlorothiazide ... Genito Urinary System and Sex Hormones …
Matched Products: … Losartan Potassium and Hydrochlorothiazide …
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Description: … These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this ... sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of ... activated partial thromboplastin time (aPTT) assay, a conventional in vitro test for biological activity of
Matched Categories: … Blood and Blood Forming Organs …
Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid and mineralocorticoid activities and toxicity.
Approved
Withdrawn
Matched Description: … Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. ... mineralocorticoid activities and toxicity. ... is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid and
Matched Categories: … Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Talimogene laherparepvec is an oncolytic treatment used in local treatment of unresectable cutaneous, subcutaneous, and nodal lesions in patients with recurrent melanoma. It is a genetically administered herpes simplex virus 1 (HSV-1) that expresses human cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) with antitumor and immune-stimulating activities. It specifically replicates within...
Approved
Experimental
Investigational
Matched Description: … Talimogene laherparepvec is an oncolytic treatment used in local treatment of unresectable cutaneous, ... It specifically replicates within tumor cells and causes lysis. ... subcutaneous, and nodal lesions in patients with recurrent melanoma. …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological...
Approved
Matched Description: … Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal ... However, sulfasalazine has less teratogenic side effects and faster onset of action compared to conventional ... [A255582] Sulfasalazine fell out of favor as the drug of choice for RA due to poorly designed clinical …
Matched Categories: … Alimentary Tract and Metabolism ... combinations of sulfonamides ... Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal …
Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment. Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture, durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote normal immune responses that attack tumour...
Approved
Investigational
Matched Description: … 1% of tumour cells and there was no observable disease progression following platinum-based chemoradiation ... locally advanced, unresectable non-small cell lung cancer (NSCLC), only if PD-L1 is expressed in ≥ ... Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Displaying drugs 126 - 150 of 14767 in total