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Displaying drugs 2176 - 2200 of 2498 in total
Experimental
Matched Categories: … Enzyme Inhibitors
L-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury.
Investigational
Matched Categories: … Enzyme Inhibitors
Pemrametostat is under investigation in clinical trial NCT03614728 (Study to Investigate the Safety and Clinical Activity of GSK3326595 and Other Agents to Treat Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)).
Investigational
Matched Categories: … Enzyme Inhibitors
Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.
Investigational
Matched Categories: … Cytochrome P-450 CYP2C9 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) …
A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary fludrocortisone. (From Martindale, The Extra Pharmacopoeia,...
Experimental
Matched Categories: … Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Experimental
Matched Categories: … Aldehyde Reductase, antagonists & inhibitors
Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia. In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment...
Investigational
Withdrawn
Matched Categories: … Enzyme Inhibitors
Edivoxetine is a drug which acts as a selective norepinephrine reuptake inhibitor and is currently under development by Eli Lilly for attention-deficit hyperactivity disorder (ADHD) and as an antidepressant treatment. Edivoxetine failed to be approved for major depressive disorder after phase III clinical trials in 2012.
Investigational
Matched Categories: … Adrenergic Uptake Inhibitors
PAC-14028 has been used in trials studying the treatment of Skin Pruritus, Papulopustular Rosacea, and Erythematotelangiectatic Rosacea.
Investigational
Matched Categories: … TRPV Cation Channels, antagonists & inhibitors
CT-2584 has been used in trials studying the treatment of Prostate Cancer.
Investigational
Matched Categories: … Phospholipase D, antagonists & inhibitors
Experimental
Matched Categories: … Aspartate Aminotransferases, antagonists & inhibitors
Doramapimod is a P38 MAP kinase inhibitor.
Investigational
Matched Categories: … Protein Kinase Inhibitors
Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
Investigational
Matched Categories: … Enzyme Inhibitors
Danusertib has been used in trials studying the treatment of Leukemia.
Investigational
Matched Categories: … Protein Kinase Inhibitors
Carmegliptin has been used in trials studying the treatment of Diabetes Mellitus Type 2.
Investigational
Matched Categories: … DPP-IV Inhibitors
A metabolite of LCZ696 with neprilysin inhibitory activity.
Experimental
Matched Categories: … Neprilysin Inhibitors
Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)).
Investigational
Matched Categories: … Enzyme Inhibitors
Experimental
Matched Categories: … Non-Nucleoside Reverse Transcriptase Inhibitors
OBP-801 has been used in trials studying the treatment of Solid Tumor.
Investigational
Matched Categories: … Histone Deacetylase Inhibitors
Ulodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint Disease.
Investigational
Matched Categories: … Purine-Nucleoside Phosphorylase, antagonists & inhibitors
AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.
Investigational
Matched Categories: … Receptors, Vascular Endothelial Growth Factor, antagonists & inhibitors
Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.
Investigational
Matched Categories: … Tryptophan Oxygenase, antagonists & inhibitors
CH5132799 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Categories: … Class I Phosphatidylinositol 3-Kinases, antagonists & inhibitors
This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a dip or wash. Coumaphos is widely used for both farm and domestic animals to control ticks, mites, flies and fleas.
Vet approved
Matched Categories: … Enzyme Inhibitors ... Cholinesterase Inhibitors
Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds.
Experimental
Vet approved
Matched Categories: … Enzyme Inhibitors ... P-glycoprotein inhibitors
Displaying drugs 2176 - 2200 of 2498 in total