Displaying drugs 1 - 25 of 279 in total
Thrombin
Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot.
Medical thrombin is a protein substance produced...
Approved
Investigational
Matched Synonyms: … Thrombin bovine ... Thrombin, Topical (Bovine) …
Matched Description: … Patients who are know or suspected to have antibodies to bovine thrombin and/or bovine factor V should ... Bleeding may result from the development of antibodies against bovine factor V [FDA Label]. ... Bovine thrombin however, is capable of causing fatal severe bleeding or thrombosis [FDA Label]. …
Matched Description: … Patients who are know or suspected to have antibodies to bovine thrombin and/or bovine factor V should ... Bleeding may result from the development of antibodies against bovine factor V [FDA Label]. ... Bovine thrombin however, is capable of causing fatal severe bleeding or thrombosis [FDA Label]. …
Desoxyribonuclease
Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into fragments approaching the size of tetranucleotides without the release of free phosphoric acid. The enzyme's cofactor is reported to be...
Approved
Matched Synonyms: … Deoxyribonuclease, bovine ... Deoxyribonuclease I bovine ... Bovine pancreatic deoxyribonuclease …
Insulin beef
Insulin beef has been discontinued in the US and Canada since 2017.
Approved
Matched Synonyms: … Insulin bovine …
Pepsin
Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products .
Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated...
Approved
Experimental
Investigational
Matched Synonyms: … Pepsin, bovine …
Matched Description: … the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated egg ... Stimulation of the pancreas and therefore enzymatic digestion of food is a tightly controlled and is ... conditions affecting metabolic steps for successful digestion and absorption negatively affect pancreatic enzymatic …
Matched Description: … the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated egg ... Stimulation of the pancreas and therefore enzymatic digestion of food is a tightly controlled and is ... conditions affecting metabolic steps for successful digestion and absorption negatively affect pancreatic enzymatic …
Casein
Casein allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Bovine casein …
Beremagene geperpavec
Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Synonyms: … Dna (recombinant herpes simplex virus type 1 strain kos plasmid vector kb103 human collagen col7a1-specifying …
Matched Description: … [L46916] DEB is caused by mutations in the _COL7A1_ gene that encodes collagen VII (COL7), a major component …
Matched Description: … [L46916] DEB is caused by mutations in the _COL7A1_ gene that encodes collagen VII (COL7), a major component …
Elapegademase
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … (74-SERINE (C>S),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, ... (CYS74>SER,ALA245>THR)ADENOSINE DEAMINASE (BOS TAURUS, BOVINE)-(1-356)-PEPTIDE, PRODUCED IN ESCHERICHIA …
Matched Description: … It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification …
Matched Description: … It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification …
Collagenase clostridium histolyticum
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease. The topical formulation is used for the debridement of necrotic tissue due to burns or chronic ulcers. On July 6,...
Approved
Investigational
Matched Description: … It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and …
Matched Mixtures name: … Collagen Film …
Matched Categories: … Collagen-specific Enzyme ... Skin and Mucous Membrane Agents …
Matched Mixtures name: … Collagen Film …
Matched Categories: … Collagen-specific Enzyme ... Skin and Mucous Membrane Agents …
Snail, unspecified
Snail, unspecified is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Products: … Black Snail Collagen Toner ... Black Snail Collagen Serum ... Black Snail Collagen EyeCream …
Rotavirus vaccine
Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. …
rhThrombin
rhThrombin (recombinant human thrombin) is being developed by ZymoGenetics, Inc. as a general aid to achieving hemostasis during surgery. ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from animal or human blood, as an aid to controlling bleeding during surgery. Thrombin is used in...
Approved
Investigational
Matched Description: … Currently, only thrombin derived from bovine blood is available in the U.S. as a stand-alone thrombin ... Bovine-derived thrombin has been associated with the development of antibodies that may cross-react with …
Heparin
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … Furthermore, the effects of UH can typically be reversed by using protamine sulfate. …
Matched Products: … HEPARINOL 10000 IU/mL (Heparin Sodium (Bovine) Injection BP 10000 IU/mL) …
Matched Products: … HEPARINOL 10000 IU/mL (Heparin Sodium (Bovine) Injection BP 10000 IU/mL) …
Hyaluronic acid
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Description: … Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “ …
Matched Mixtures name: … Collagen Film ... Le-Blen Nano Collagen Peptide Serum ... OUHOE Retinol Collagen Complex Day Night Cream …
Matched Mixtures name: … Collagen Film ... Le-Blen Nano Collagen Peptide Serum ... OUHOE Retinol Collagen Complex Day Night Cream …
Cortisone acetate
Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.[A226300,L13203]
Cortisone acetate...
Approved
Investigational
Matched Description: … cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Salts name: … Amikacin sulfate …
Matched Products: … Amikacin Sulfate ... AMIKACIN Sulfate ... AMIKACIN SULFATE …
Matched Products: … Amikacin Sulfate ... AMIKACIN Sulfate ... AMIKACIN SULFATE …
Sodium zirconium cyclosilicate
Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Ascorbic acid
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Mixtures name: … Collagen Boost Cream ... Highprime Collagen Film ... Total Image Collagen Plus …
Matched Products: … GENOLIFE COLLAGEN PLUS VITAMIN C CAPSULE …
Matched Products: … GENOLIFE COLLAGEN PLUS VITAMIN C CAPSULE …
Fenoprofen
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Panthenol
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic …
Betaine
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Mixtures name: … Wizyoung Vitamin Collagen Essence Mask Pack ... Wizyoung Diamond Collagen Essence Mask Pack …
Polyethylene glycol
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … intestinal absorption with increasing molecular mass, lack of significant toxicity, and limited intestinal enzymatic …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid …
Fidaxomicin
Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by Clostridioides (formerly Clostridium) difficile in adult and pediatric patients over the age of 6 months. Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation. Because fidaxomicin contains an 18-membered lactone ring in its structure, it is...
Approved
Fluorometholone
A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Approved
Investigational
Histamine
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Approved
Investigational
Matched Description: … A depressor amine derived by enzymatic decarboxylation of histidine. …
Rose bengal
Rose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. It is also used in laboratory settings, including the preparation of Foraminifera for microscopic analysis and suppression...
Approved
Investigational
Displaying drugs 1 - 25 of 279 in total