Displaying all 4 drugs
Maftivimab
Ebola virus (EBOV) remains an important human pathogen within the Ebolavirus genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid...
Approved
Matched Synonyms: … Maftivimab …
Matched Name: … Maftivimab …
Matched Description: … (REGN 3479), [Odesivimab] (REGN 3471), and [Atoltivimab] (REGN 3470) in equimolar proportions. ... [A222078] INMAZEB™, formerly referred to as REGN-EB3, combines the three humanized IgG1κ mAbs Maftivimab ... neutralizing and Fc-mediated immune effector function against EBOV _in vitro_ and protection against …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Maftivimab …
Matched Description: … (REGN 3479), [Odesivimab] (REGN 3471), and [Atoltivimab] (REGN 3470) in equimolar proportions. ... [A222078] INMAZEB™, formerly referred to as REGN-EB3, combines the three humanized IgG1κ mAbs Maftivimab ... neutralizing and Fc-mediated immune effector function against EBOV _in vitro_ and protection against …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Atoltivimab
Ebola virus (EBOV) remains an important human pathogen within the Ebolavirus genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid...
Approved
Matched Synonyms: … Atoltivimab …
Matched Name: … Atoltivimab …
Matched Description: … (REGN 3470), [Odesivimab] (REGN 3471), and [Maftivimab] (REGN 3479) in equimolar proportions. ... [A222078] INMAZEB™, formerly referred to as REGN-EB3, combines the three humanized IgG1κ mAbs Atoltivimab ... neutralizing and Fc-mediated immune effector function against EBOV _in vitro_ and protection against …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Atoltivimab …
Matched Description: … (REGN 3470), [Odesivimab] (REGN 3471), and [Maftivimab] (REGN 3479) in equimolar proportions. ... [A222078] INMAZEB™, formerly referred to as REGN-EB3, combines the three humanized IgG1κ mAbs Atoltivimab ... neutralizing and Fc-mediated immune effector function against EBOV _in vitro_ and protection against …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ansuvimab
Infection with pathogenic filoviruses, such as Zaire ebolavirus (Ebola virus, EBOV), can cause severe hemorrhagic fever in humans, resulting in frequent outbreaks with case fatality rates as high as 90%.[A225933, A225938] Virtually all steps of the EBOV lifecycle have been targeted for therapeutic development. However, to date, the most successful...
Approved
Investigational
Matched Description: … ], [odesivimab], and [maftivimab]), the now approved ansuvimab, and ZMapp, which remains in clinical ... sub> surface glycoprotein, as evidenced by the previously approved INMAZEB™ (REGN-EB3, a cocktail of [atoltivimab ... to be superior, with improved patient survival and faster viral clearance rates. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Odesivimab
Ebola virus (EBOV) remains an important human pathogen within the Ebolavirus genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid...
Approved
Matched Synonyms: … Odesivimab ... odesivimab-ebgn …
Matched Name: … Odesivimab …
Matched Description: … (REGN 3471), [Maftivimab] (REGN 3479), and [Atoltivimab] (REGN 3470) in equimolar proportions. ... [A222078] INMAZEB™, formerly referred to as REGN-EB3, combines the three humanized IgG1κ mAbs Odesivimab ... neutralizing and Fc-mediated immune effector function against EBOV _in vitro_ and protection against …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Odesivimab …
Matched Description: … (REGN 3471), [Maftivimab] (REGN 3479), and [Atoltivimab] (REGN 3470) in equimolar proportions. ... [A222078] INMAZEB™, formerly referred to as REGN-EB3, combines the three humanized IgG1κ mAbs Odesivimab ... neutralizing and Fc-mediated immune effector function against EBOV _in vitro_ and protection against …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying all 4 drugs