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Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine.[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than dolutegravir. The devlopment of cabotegravir was later developed to create a long acting monthly intramuscular injection.[A227668,L31193] Cabotegravir was granted FDA approval...
Approved
Investigational
Matched Synonyms: … Cabotegravir
Matched Name: … Cabotegravir
Matched Description: … reverse transcriptase inhibitor, [rilpivirine]. ... [A227668,L31193] Cabotegravir was granted FDA approval on 21 January 2021.[L31198] ... Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside …
Matched Salts name: … Cabotegravir sodium …
Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance...
Approved
Matched Synonyms: … Rilpivirine
Matched Name: … Rilpivirine
Matched Description: … [L1031] Rilpivirine in combination with [cabotegravir] was granted FDA approval on 21 January 2021. ... [A31331] Rilpivirine was developed by Tilbotec, Inc. and FDA approved on May 20, 2011. ... [A31329] The internal conformational flexibility of rilpivirine and the plasticity of it interacting …
Matched Mixtures name: … Odefsey┬« (200mg Emtricitabine/25mg Rilpivirine/25mg Tenofovir alafenamide) film coated tablets …
Matched Salts name: … Rilpivirine hydrochloride …
Matched Categories: … dolutegravir and rilpivirine ... emtricitabine, tenofovir disoproxil and rilpivirine ... emtricitabine, tenofovir alafenamide and rilpivirine ... rilpivirine
Displaying all 2 drugs