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Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … Darunavir
Matched Name: … Darunavir
Matched Description: … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066] ... Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] ... [L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard …
Matched Salts name: … Darunavir ethanolate ... Darunavir propylene glycolate …
Matched Categories: … darunavir and cobicistat ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat ... darunavir and ritonavir ... darunavir ... Genito Urinary System and Sex Hormones …
Matched Products: … Darunavir ... DARUNAVIR TEVA ... M-darunavir
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Description: … combined with [tenofovir alafenamide] for the prevention of HIV-1 infection in high risk adolescents and
Matched Mixtures name: … Genvoya (Elvitegravir 150mg/Cobicistat 150mg/Emtricitabine 200mg/Tenofovir alafenamide10mg) Film-Coated ... Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate …
Matched Categories: … emtricitabine, tenofovir alafenamide, darunavir and cobicistat ... emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat ... emtricitabine, tenofovir alafenamide, elvitegravir and cobicistat ... tenofovir disoproxil and emtricitabine ... emtricitabine and tenofovir alafenamide …
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Synonyms: … Cobicistat
Matched Name: … Cobicistat
Matched Description: … More specifically, cobicistat is indicated to increase systemic exposure of atazanavir or darunavir ( ... cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and
Matched Mixtures name: … Genvoya (Elvitegravir 150mg/Cobicistat 150mg/Emtricitabine 200mg/Tenofovir alafenamide10mg) Film-Coated …
Matched Categories: … darunavir and cobicistat ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat ... atazanavir and cobicistat ... emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat ... emtricitabine, tenofovir alafenamide, elvitegravir and cobicistat
Tenofovir alafenamide is a novel tenofovir prodrug developed in order to improve renal safety when compared to the counterpart tenofovir disoproxil. Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal...
Approved
Matched Description: … group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and ... [L4388,L9010] Tenofovir alafenamide was developed by Gilead Sciences Inc and granted FDA approval ... alafenamide is indicated to treat chronic hepatitis B,[L6241] treat HIV-1,[L4388,L6277,L6280,L6283] and
Matched Mixtures name: … Genvoya (Elvitegravir 150mg/Cobicistat 150mg/Emtricitabine 200mg/Tenofovir alafenamide10mg) Film-Coated …
Matched Categories: … emtricitabine, tenofovir alafenamide, darunavir and cobicistat ... emtricitabine, tenofovir alafenamide, elvitegravir and cobicistat ... Tenofovir and prodrugs ... Amino Acids, Peptides, and Proteins ... emtricitabine and tenofovir alafenamide …
Displaying all 4 drugs