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Displaying drugs 1 - 25 of 562 in total
Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Synonyms: … Dimeticona ... Dimethicone ... Dimeticone
Matched Name: … Dimethicone
Matched Description: … Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). ... A study found that that the 100 % dimethicone product is a safe and highly effective head lice treatment ... It is used in a number of health and beauty products including hair care products such as shampoo, conditioner …
Matched Mixtures name: … Zinc Oxide and Dimethicone with Dimethicone ... DIMETHICONE and ZINC OXIDE ... DIMETHICONE and PETROLATUM …
Matched Salts name: … Dimethicone 100 …
Matched Categories: … dimeticone ... Compounds used in a research, industrial, or household setting ... Basic Ointments and Protectants ... Scabicides and Pediculicides ... Skin and Mucous Membrane Agents …
Matched Products: … Aveeno Skin Relief Gentle Scent Soothing Oat and Chamomile ... Super Serum Anti Aging and Firming ... Dimethicone
Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Synonyms: … Padimate O ... Padimate-O
Matched Name: … Padimate O
Matched Description: … Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in ... It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic ... effects on yeast i_n vivo_ [A32458]. …
Matched Mixtures name: … Sun and Ski Stick SPF 15 ... Aruba Aloe Lip Sunscreen and Moisturizer ... Phineas and Ferb Sun Smacker SPF 24 Berry Busted …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Hand and Body Lotion SPF 15 ... Green Tea and Ginkgo Moisturizer SPF 10 ... Medicated Lip Balm - Ont Top 8% …
CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. These cells are currently being investigated against lung injury and fibrosis -- conditions which are...
Investigational
Matched Synonyms: … immunity- and matrix-regulatory cells ... Immunity-and-matrix-regulatory cells …
Matched Description: … immunomodulatory and anti-fibrotic functions, and being stronger in potential treatment of lung injury ... CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can ... IMRCs are similar to MSCs in terms of their capacity for self-renewal and tri-lineage differentiation …
Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L14501, L1510]. Vayarin is currently available...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... [L35525] Stratagraft consists of two kinds of lab-grown skin cells, keratinocytes and dermal fibroblasts ... is harvested and grafted onto the burn site - which has the disadvantage of creating a new wound at …
VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide of meningococcal group C. As there already exists a polysaccharide-based vaccine against meningococcal disease originating from serogroups A,C,W135, and...
Investigational
Matched Synonyms: … Meningococcal polysaccharide vaccine groups B and C …
Matched Description: … VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. ... of meningococcal group C. ... The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide …
PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental blood. It is developed by Cellpraxis and is currently being investigated against severe acute respiratory syndrome (SARS).
Investigational
Matched Synonyms: … Human umbilical cord and placental blood plasma …
Matched Description: … PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental ... [L27581] It is developed by Cellpraxis and is currently being investigated against severe acute respiratory …
Padimate A is an ester derivative of PABA and an ingredient in some sunscreens. It absorbs ultraviolet rays thereby preventing sunburn, however, its chemical structure and behaviour is similar to an industrial free radical generator. In Europe this chemical was withdrawn in 1989 for unstated reasons and in the US...
Experimental
Withdrawn
Matched Synonyms: … Padimate ... Padimate A …
Matched Name: … Padimate A …
Matched Description: … Padimate A is an ester derivative of PABA and an ingredient in some sunscreens. ... It absorbs ultraviolet rays thereby preventing sunburn, however, its chemical structure and behaviour ... In Europe this chemical was withdrawn in 1989 for unstated reasons and in the US it was never approved …
CD24Fc is a biological immunomodulator originally developed to address graft-versus-host disease in stem cell transplantation in leukemia patients.
Investigational
Matched Synonyms: … Human CD24 and human IgG Fc Fusion Protein …
Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity ... [A228508] Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily ... relieve nasal congestion due to cold, hay fever or other respiratory allergies. …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops ... Otrivin Allergy and Cold Decongestant Nasal Spray …
Polysilicone-15 is a silicone based UVB absorber [L2796, L2797, L2799, F87, F88, F89]. The compound is a colorless to pale yellow viscous liquid which is soluble in organic solvents of medium polarity and insoluble in water [L2796, L2797, L2799, F87, F88, F89]. It is the first polymeric UVB filer consisting...
Approved
Matched Synonyms: … Diethylbenzylidene malonate dimethicone ... Diethylmalonylbenzylidene oxypropene dimethicone
Matched Description: … polarity and insoluble in water [L2796, L2797, L2799, F87, F88, F89]. ... as an effective photostabilizer of the product [L2796, L2797, L2799, F87, F88, F89]. ... The compound is a colorless to pale yellow viscous liquid which is soluble in organic solvents of medium …
Matched Mixtures name: … The History Of Whoo Gongjinhyang Seol Whitening Sun …
Penicillium glaucum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, penicillium glaucum ... Molds, rusts and smuts, penicillium glaucus …
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Synonyms: … Oxybenzone ... Oxybenzonum
Matched Name: … Oxybenzone
Matched Description: … Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. ... It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays …
Matched Mixtures name: … Oil Free Matte Sunscreen SPF 30, - Zinc Oxide, Octinoxate, Octisalate, Oxybenzone ... OP Protect and Renew Body SPF 45 ... Avobenzone, Homosalate, Octisalate, Octocrylene, Oxybenzone
Matched Categories: … Compounds used in a research, industrial, or household setting …
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces, patients ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Iupac: … hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Matched Description: … [A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. ... [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named ... Compound F, or 17-hydroxycorticosterone. …
Matched Mixtures name: … Oti Rx ... Poison Oak ... Oto End 10 …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... Hydrocortisone and derivatives ... hydrocortisone and mydriatics …
Matched Products: … Up and Up Hydrocortisone One Per Cent ... Rodan and Fields Soothe ... Itch and Rash Cream …
Sarocladium strictum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, acremonium strictum ... Molds, rusts and smuts, cephalosporium acremonium …
Matched Products: … Molds, Rusts and Smuts, Cephalosporium acremonium …
Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Gp96-igg1-fc fusion protein and hla-a1 expressing, irradiated ad-100 whole cell vaccine …
Matched Description: … Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l …
Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … for the prophylaxis and control of bleeding episodes. ... prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia ... Exogenous replacement of Factor VIII is currently the cornerstone of Hemophilia treatment and is used …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …
Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Iupac: … carbamoylamino)phenyl]-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1R)-1-carbamoylethyl]carbamoyl}pyrrolidin-1-yl]-1-oxo
Matched Description: … derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately ... FDA approved on December 24, 2008. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …
Pyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. In the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat...
Approved
Matched Description: … of proteins essential for fungal metabolism and growth [A27132]. ... Other uses of pyrithione zinc include additive in antifouling outdoor paints and algaecide. ... Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused …
Matched Mixtures name: … Head and Shoulders Dual Sachets Full and Strong ... Head and Shoulders Dual Sachets Full and Strong ... Head and Shoulders Dual Sachets Smooth and Silky …
Matched Products: … Head and Shoulders Old Spice ... Head and Shoulder Men Old Spice ... Head and Shoulders Men Old Spice …
Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective...
Approved
Matched Description: … effect and modulation of the microbial composition of the dental biofilm [A19581]. ... of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. ... It manages and prevents dental caries and gingivitis by promoting enamel mineralization [A19580], reducing …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting …
Matched Products: … Care One Restore and Defend Sensitive Whitening ... 0.4% Stannous Fluoride Brush On Gel ... Crest Pro-Health With a Touch of Scope …
Atacicept is a recombinant fusion protein combined with the extracellular ligand binding portion of TACI.
Investigational
Matched Synonyms: … Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein ( …
Matched Description: … Atacicept is a recombinant fusion protein combined with the extracellular ligand binding portion of TACI …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Description: … An ophthalmic solution of olopatadine was approved by the FDA and European Union for the treatment of ... seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... inflammatory and allergic reactions. …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... OLO-A-DAY ... Eye Allergy Itch and Redness Relief Twice Daily Relief …
Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …
Displaying drugs 1 - 25 of 562 in total