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Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets the the viral RNA replication and viron assembly. In combination with DB13879, pibrentastiv is a useful therapy for patients who experienced therapeutic failure from other NS5A inhibitors. In cell cultures, the emergence of amino...
Approved
Investigational
Matched Synonyms: … Pibrentasvir
Matched Name: … Pibrentasvir
Matched Description: … Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets ... resistance to pibrentasvir [FDA Label]. ... Individual NS5A amino acid substitutions that reduced susceptibility to pibrentasvir include M28G or …
Matched Categories: … glecaprevir and pibrentasvir
Glecaprevir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS3/4A protease inhibitor that targets the the viral RNA replication. In combination with DB13878, glecaprevir is a useful therapy for patients who experienced therapeutic failure from other NS3/4A protease inhibitors. It demonstrates a high genetic barrier against resistance...
Approved
Investigational
Matched Synonyms: … Glecaprevir
Matched Name: … Glecaprevir
Matched Description: … reductions in glecaprevir susceptibility, and NS3 Q80R in genotype 3a patients also leads to glecaprevir ... Glecaprevir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS3/4A protease inhibitor ... In combination with [DB13878], glecaprevir is a useful therapy for patients who experienced therapeutic …
Matched Categories: … glecaprevir and pibrentasvir
Displaying all 2 drugs