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Displaying drugs 1 - 25 of 840 in total
Melphalan flufenamide, also known as melflufen or J1, is a prodrug of melphalan.[A230123,L32173] Melphalan flufenamide is more readily uptaken by cells than melphalan, and is cleaved to the active metabolite by aminopeptidases. In vitro models show that melphalan is 10 to hundreds of times more potent than melphalan. The increased...
Approved
Matched Synonyms: … Melphalan flufenamide
Matched Name: … Melphalan flufenamide
Matched Description: … Melphalan flufenamide, also known as melflufen or J1, is a prodrug of [melphalan]. ... [A230123,L32173] Melphalan flufenamide is more readily uptaken by cells than melphalan, and is cleaved ... [A230143,L32173] Melphalan flufenamide was granted FDA approval on 26 February 2021.[L32173] …
An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - melphalan, the racemic mixture - merphalan, and the dextro isomer - medphalan; toxic to bone marrow, but little vesicant action; potential carcinogen.
Approved
Matched Synonyms: … Melphalan
Matched Name: … Melphalan
Matched Description: … An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - melphalan
Matched Mixtures name: … Taro-melphalan ... Melphalan for Injection ... Melphalan for Injection …
Matched Salts name: … Melphalan hydrochloride
Matched Categories: … melphalan
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride ... Melphalan
Amitriptyline hydrochloride, also known as Elavil, is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain . It was originally approved by the FDA in 1977 and manufactured by Sandoz .
Approved
Matched Description: … Amitriptyline hydrochloride, also known as _Elavil_, is a tricyclic antidepressant (TCA) with analgesic …
Matched Mixtures name: … Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride
Matched Salts name: … Amitriptyline hydrochloride
Matched Products: … Amitriptyline Hydrochloride ... AMITRIPTYLINE HYDROCHLORIDE ... Amitriptyline hydrochloride
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Mixtures name: … Azelastine hydrochloride and Fluticasone propionate ... Azelastine Hydrochloride and Fluticasone Propionate ... Azelastine Hydrochloride and Fluticasone Propionate …
Matched Salts name: … Azelastine hydrochloride
Matched Products: … Azelastine Hydrochloride ... Azelastine Hydrochloride Ophthalmic Solution 0.05% …
A benzodiazepine derivative used mainly as a hypnotic.
Approved
Illicit
Investigational
Matched Salts name: … Flurazepam hydrochloride
Matched Products: … Flurazepam Hydrochloride
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Salts name: … Cocaine hydrochloride
Matched Products: … Cocaine Hydrochloride ... Cocaine Hydrochloride Nasal ... Cocaine Hydrochloride Top Sol 40mg/ml …
A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Mixtures name: … Meperidine Hydrochloride and Promethazine Hydrochloride
Matched Salts name: … Meperidine hydrochloride
Matched Products: … Meperidine Hydrochloride ... Meperidine Hydrochloride Injection USP ... DBL PETHIDINE HYDROCHLORIDE INJECTION BP 50mg/ml …
An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Approved
Illicit
Investigational
Matched Mixtures name: … Chlordiazepoxide and Amitriptyline Hydrochloride ... Chlordiazepoxide and Amitriptyline Hydrochloride ... Chlordiazepoxide Hydrochloride and Clidinium Bromide …
Matched Salts name: … Chlordiazepoxide hydrochloride
Matched Products: … Chlordiazepoxide Hydrochloride
Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe...
Approved
Illicit
Investigational
Withdrawn
Matched Mixtures name: … Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen …
Matched Salts name: … Dextropropoxyphene hydrochloride
Matched Products: … Propoxyphene Hydrochloride
Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Mixtures name: … Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride
Matched Salts name: … Oxybuprocaine hydrochloride
Matched Products: … Minims Benoxinate Hydrochloride 0.4% …
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Salts name: … Labetalol hydrochloride
Matched Products: … Labetalol Hydrochloride ... Labetalol hydrochloride ... Labetalol Hydrochloride Injection …
Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Salts name: … Tetracaine hydrochloride
Matched Products: … Tetracaine Hydrochloride ... 0.5% TETRACAINE HYDROCHLORIDE ... Minims Tetracaine Hydrochloride
Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Description: … [T691] Hydralazine hydrochloride was FDA approved on 15 January 1953.[L8779] …
Matched Salts name: … Hydralazine hydrochloride
Matched Products: … Hydralazine Hydrochloride ... HydrALAZINE Hydrochloride ... Apresoline hydrochloride
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. ... [A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992. …
Matched Salts name: … Terbinafine hydrochloride
Matched Products: … Terbinafine Hydrochloride ... GoodSense Terbinafine Hydrochloride ... KAISER PERMANENTE Terbinafine Hydrochloride
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride
Matched Salts name: … Verapamil hydrochloride
Matched Products: … Verapamil Hydrochloride ... Verapamil hydrochloride ... Verapamil Hydrochloride PM …
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Salts name: … Olopatadine hydrochloride
Matched Products: … Olopatadine Hydrochloride ... Olopatadine Hydrochloride Nasal ... Olopatadine Hydrochloride Ophthalmic Solution …
Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive...
Approved
Matched Description: … Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). …
Matched Salts name: … Protriptyline hydrochloride
Matched Products: … Protriptyline Hydrochloride ... Protriptyline hydrochloride
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Description: … Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts name: … Nortriptyline hydrochloride
Matched Products: … Nortriptyline Hydrochloride
Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. Phentermine has not been reported an addictive potential which allows this agent to...
Approved
Illicit
Matched Salts name: … Phentermine hydrochloride
Matched Products: … Phentermine Hydrochloride ... Phentermine hydrochloride ... Phetermine Hydrochloride
Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) Internationally, diamorphine is controlled under...
Approved
Illicit
Investigational
Matched Salts name: … Diamorphine hydrochloride
Matched Products: … Diamorphine Hydrochloride Inj 30mg/ml BP ... Diamorphine Hydrochloride Inj 100mg/ml BP …
A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Salts name: … Demeclocycline hydrochloride
Matched Products: … Demeclocycline Hydrochloride
Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Phenazopyridine hydrochloride
Matched Products: … Phenazopyridine Hydrochloride ... Phenazopyridine hydrochloride ... Phenazopyridine Hydrochloride 97.5mg …
A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. It is no longer marketed in the United States, as it has been implicated in causing...
Approved
Withdrawn
Matched Salts name: … Bepridil hydrochloride
Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspirone does...
Approved
Investigational
Matched Salts name: … Buspirone hydrochloride
Matched Products: … Buspirone Hydrochloride ... BusPIRone Hydrochloride ... Buspirone hydrochloride
Chloroprocaine hydrochloride is a local anesthetic given by injection during surgical procedures and labor and delivery. Chloroprocaine, like other local anesthetics, blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse and...
Approved
Matched Description: … Chloroprocaine hydrochloride is a local anesthetic given by injection during surgical procedures and …
Matched Salts name: … Chloroprocaine hydrochloride
Matched Products: … Chloroprocaine Hydrochloride
Displaying drugs 1 - 25 of 840 in total