Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.
Article Details
- CitationCopy to clipboard
Letavic MA, Stocking EM, Barbier AJ, Bonaventure P, Boggs JD, Lord B, Miller KL, Wilson SJ, Carruthers NI
Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.
Bioorg Med Chem Lett. 2007 Sep 1;17(17):4799-803. Epub 2007 Jun 26.
- PubMed ID
- 17616397 [ View in PubMed]
- Abstract
The design, synthesis, and in vitro activity of a series of novel 5-ethynyl-2-aryloxybenzylamine-based histamine H(3) ligands that are also serotonin reuptake transporters is described.
DrugBank Data that Cites this Article
- Binding Properties
Drug Target Property Measurement pH Temperature (°C) Fluoxetine Sodium-dependent serotonin transporter Ki (nM) 2.2 N/A N/A Details