Mucin-2
Details
- Name
- Mucin-2
- Kind
- protein
- Synonyms
- Intestinal mucin-2
- MUC-2
- SMUC
- Gene Name
- MUC2
- UniProtKB Entry
- Q02817Swiss-Prot
- Organism
- Humans
- NCBI Taxonomy ID
- 9606
- Amino acid sequence
>lcl|BSEQ0057141|Mucin-2 MGLPLARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCD YNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTP HYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSE FLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDL VPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLV YLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLY TPGQEITNDCEQCVCNAGRWVCKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKG DHNDSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTA SFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFK TASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGR CHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGS CPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSC YHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPR ALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCN TCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSF SIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVV ESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNS WKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSC SCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNR SFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA SVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITT RPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDD GDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQCDVSVGFICKNEDQFGNGPFGLCY DYKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSP PITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP SPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTT PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPP TTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFH KPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTP ITTTNTVTPTPTPTGTQTPTPTPITTTTTMVTPTPTITSTQTPTPTPITTTTVTPTPTPT STQRTTPTSITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPISTTT MVTPTPTPTGTQTLTPTPITTTTTVTPTPTPTGTQTPTSTPISTTTTVTPTPTPTGTQTP TLTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTKSTTPTSITTTTMVTPT PPPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTPITTTTTVTPTPTPTGTQTPTSTPI TTNTTVTPTPTPTGTPSTTLTPITTTTMVTPTPTPTGTQTPTSTPISTTTTVTPTPTPTG TQTPTPTPISTTTTVTPTPTPTSTQTPTTTPITTTTTVTPNPTPTGTQTPTTTPITTTTT VTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQTPTTTAITTTTTVTPTPTPTGTQTPT STPITTTTTVTPTPTPTGTQTPTSTPISNTTTVTPTPTPTGTQTPTVTPITTTTTVTPTR TPTGTKSTTPTSITTTTMVTPTPTPTGTHTPTTTPITTTTTVTPTPTPTGTQTPTPTPIT TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTNTTVTPTPTPTGT QTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTPTPTPTGTQSTTLTPITTTTTV TPTPTPTGTQTPTTTPISTTTTVIPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTS TPISTTTTVTPTATPTGTQTPTLTPITTTTTVTSTPTPTGTQTPTPTPITTTTTVTPTPT PTSTQTPTSTPITTTTTVTPTPTPTGTQTPTTTHITTTTTVTPTPTPTGTQAPTPTAITT TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQSPTPTAITTTTTVTPTPTPTGTQ TPTTTPITTTTTVTPTPTPTGTQSTTLTPITTTTTVTPIPTPTGTQTPTSTPITTTITVT PTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT PISTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPITTTTTVTPTPTP TGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPITTTTTVTPTPTPTGTQTPTSTPITTT TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQSTTLTPITTTTTVTPTPTPTGTQT PTSTPITTTTTVTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTMTPITTTTTVTPTP TPTGTQTPTTTPISTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPIT TTTTVTPTPTPTGTQSTTLTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGT QTPTTTPITTTTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQTPTSTPITTTTTV TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTTTVTPTPTPTGTQTPTT TPITTTTMVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPT PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQTPTSTPITT TTTVTPTPTPTGTQTPTPTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ TPTTTPITTTTTVTPTPTPTGTQSTTLTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVT PTPTPTGTQTPTPTPISTTSTVTPTPTPTGTQTPTMTPITTTTTVTPTPTPTGTQTPTST PITTTTTVTPTPTPTGTQTPTMTPITTTTTVTPTPTPTGTQAPTPTAITTTTTVTPTPTP TGTQTPTTTPITTTTTVTPTPTPTGTQSTTLTPITTTTTVTPTPTPTGTQTPTPTPISTT TTVTPTPTPTGTQTPTMTPITTTTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQT PTTTPITTTTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTP TPTPTGTQTPTTTPISTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTP ITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT GTQSPTPTAITTTTTVTPTPTPTGTQTPTLTPITTTTTVTPTPTPTGTQTPTPTPISTTT TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKST TVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELT TSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSP PPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPS SVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKST PTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEP PPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVA LPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTS DDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPS PLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDW RNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDV CVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLA TEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGN AEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKC EQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICI PGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSA KAQALDHSCSCCKEEKTSQREVVLSCPNGGSLTHTYTHIESCQCQDTVCGLPTGTSRRAR RSPRHLGSG
- Number of residues
- 5289
- Molecular Weight
- 550846.44
- Theoretical pI
- 5.63
- GO Classification
- Processesmaintenance of gastrointestinal epitheliumComponentsGolgi lumen / inner mucus layer / outer mucus layer
- General Function
- Coats the epithelia of the intestines and other mucus membrane-containing organs to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (PubMed:17058067, PubMed:19432394, PubMed:33031746). Major constituent of the colon mucus, which is mainly formed by large polymeric networks of MUC2 secreted by goblet cells that cover the exposed surfaces of intestine (PubMed:19432394, PubMed:33031746). MUC2 networks form hydrogels that guard the underlying epithelium from pathogens and other hazardous matter entering from the outside world, while permitting nutrient absorption and gas exchange (PubMed:33031746, PubMed:36206754). Acts as a divalent copper chaperone that protects intestinal cells from copper toxicity and facilitates nutritional copper unptake into cells (PubMed:36206754). Binds both Cu(2+) and its reduced form, Cu(1+), at two juxtaposed binding sites: Cu(2+), once reduced to Cu(1+) by vitamin C (ascorbate) or other dietary antioxidants, transits to the other binding site (PubMed:36206754). MUC2-bound Cu(1+) is protected from oxidation in aerobic environments, and can be released for nutritional delivery to cells (PubMed:36206754). Mucin gels store antimicrobial molecules that participate in innate immunity (PubMed:33031746). Mucin glycoproteins also house and feed the microbiome, lubricate tissue surfaces, and may facilitate the removal of contaminants and waste products from the body (PubMed:33031746). Goblet cells synthesize two forms of MUC2 mucin that differ in branched chain O-glycosylation and the site of production in the colon: a (1) 'thick' mucus that wraps the microbiota to form fecal pellets is produced in the proximal, ascending colon (By similarity). 'Thick' mucus transits along the descending colon and is lubricated by a (2) 'thin' MUC2 mucus produced in the distal colon which adheres to the 'thick' mucus (By similarity)
- Specific Function
- cupric ion binding
- Pfam Domain Function
- Signal Regions
- 1-20
- Transmembrane Regions
- Not Available
- Cellular Location
- Secreted
- Gene sequence
>lcl|BSEQ0010724|Mucin-2 (MUC2) ATGGGGCTGCCACTAGCCCGCCTGGCGGCTGTGTGCCTGGCCCTGTCTTTGGCAGGGGGC TCGGAGCTCCAGACAGAGGGCAGAACCCGAAACCACGGCCACAACGTCTGCAGCACCTGG GGCAACTTCCACTACAAGACCTTCGACGGGGACGTCTTCCGCTTCCCCGGCCCCTGCGAC TACAACTTCGCCTCCGACTGCCGAGGCTCCTACAAGGAATTTGCTGTGCACCTGAAGCGG GGTCCGGGCCAGGCTGAGGCCCCCGCCGGGGTGGAGTCCATCCTGCTGACCATCAAGGAT GACACCATCTACCTCACCCGCCACCTGGCTGTGCTTAACGGGGCCGTGGTCAGCACCCCG CACTACAGCCCCGGGCTGCTCATTGAGAAGAGCGATGCCTACACCAAAGTCTACTCCCGC GCCGGCCTCACCCTCATGTGGAACCGGGAGGATGCACTCATGCTGGAGCTGGACACTAAG TTCCGGAACCACACCTGTGGCCTCTGCGGGGACTACAACGGCCTGCAGAGCTATTCAGAA TTCCTCTCTGACGGCGTGCTCTTCAGTCCCCTGGAGTTTGGGAACATGCAGAAGATCAAC CAGCCCGATGTGGTGTGTGAGGATCCCGAGGAGGAGGTGGCCCCCGCATCCTGCTCCGAG CACCGCGCCGAGTGTGAGAGGCTGCTGACCGCCGAGGCCTTCGCGGACTGTCAGGACCTG GTGCCGCTGGAGCCGTATCTGCGCGCCTGCCAGCAGGACCGCTGCCGGTGCCCGGGCGGT GACACCTGCGTCTGCAGCACCGTGGCCGAGTTCTCCCGCCAGTGCTCCCACGCCGGCGGC CGGCCCGGGAACTGGAGGACCGCCACGCTCTGCCCCAAGACCTGCCCCGGGAACCTGGTG TACCTGGAGAGCGGCTCGCCCTGCATGGACACCTGCTCACACCTGGAGGTGAGCAGCCTG TGCGAGGAGCACCGCATGGACGGCTGTTTCTGCCCAGAAGGCACCGTATATGACGACATC GGGGACAGTGGCTGCGTTCCTGTGAGCCAGTGCCACTGCAGGCTGCACGGACACCTGTAC ACACCGGGCCAGGAGATCACCAATGACTGCGAGCAGTGTGTCTGTAACGCTGGCCGCTGG GTGTGCAAAGACCTGCCCTGCCCCGGCACCTGTGCCCTGGAAGGCGGCTCCCACATCACC ACCTTCGATGGGAAGACGTACACCTTCCACGGGGACTGCTACTATGTCCTGGCCAAGGGT GACCACAACGATTCCTACGCTCTCCTGGGCGAGCTGGCCCCCTGTGGCTCCACAGACAAG CAGACCTGCCTGAAGACGGTGGTGCTGCTGGCTGACAAGAAGAAGAATGTGGTGGTCTTC AAGTCCGATGGCAGTGTACTGCTCAACGAGCTGCAGGTGAACCTGCCCCACGTGACCGCG AGCTTCTCTGTCTTCCGCCCGTCTTCCTACCACATCATGGTGAGCATGGCCATTGGCGTC CGGCTGCAGGTGCAGCTGGCCCCAGTCATGCAACTCTTTGTGACACTGGACCAGGCCTCC CAGGGGCAGGTGCAGGGCCTCTGCGGGAACTTCAACGGCCTGGAAGGTGACGACTTCAAG ACGGCCAGCGGGCTGGTGGAGGCCACGGGGGCCGGCTTTGCCAACACCTGGAAGGCACAG TCAACCTGCCATGACAAGCTGGACTGGTTGGACGATCCCTGCTCCCTGAACATCGAGAGC GCCAACTACGCCGAGCACTGGTGCTCCCTCCTGAAGAAGACAGAGACCCCCTTTGGCAGG TGCCACTCGGCTGTGGACCCTGCTGAGTATTACAAGAGGTGCAAATATGACACGTGTAAC TGTCAGAACAATGAGGACTGCCTGTGCGCCGCCCTGTCCTCCTACGCGCGCGCCTGCACC GCCAAGGGCGTCATGCTGTGGGGCTGGCGGGAGCATGTCTGCAACAAGGATGTGGGCTCC TGCCCCAACTCGCAGGTCTTCCTGTACAACCTGACCACCTGCCAGCAGACCTGCCGCTCC CTCTCCGAGGCCGACAGCCACTGTCTCGAGGGCTTTGCGCCTGTGGACGGCTGCGGCTGC CCTGACCACACCTTCCTGGACGAGAAGGGCCGCTGCGTACCCCTGGCCAAGTGCTCCTGT TACCACCGCGGTCTCTACCTGGAGGCGGGGGACGTGGTCGTCAGGCAGGAAGAACGATGT GTGTGCCGGGATGGGCGGCTGCACTGTAGGCAGATCCGGCTGATCGGCCAGAGCTGCACG GCCCCAAAGATCCACATGGACTGCAGCAACCTGACTGCACTGGCCACCTCGAAGCCCCGA GCCCTCAGCTGCCAGACGCTGGCCGCCGGCTATTACCACACAGAGTGTGTCAGTGGCTGT GTGTGCCCCGACGGGCTGATGGATGACGGCCGGGGTGGCTGCGTGGTGGAGAAGGAATGC CCTTGCGTCCATAACAACGACCTGTATTCTTCCGGCGCCAAGATCAAGGTGGACTGCAAT ACCTGCACCTGCAAGAGAGGACGCTGGGTGTGCACCCAGGCTGTGTGCCATGGCACCTGC TCCATTTACGGGAGTGGCCACTACATCACCTTTGACGGGAAGTACTACGACTTTGACGGA CACTGCTCCTACGTGGCTGTTCAGGACTACTGCGGCCAGAACTCCTCACTGGGCTCATTC AGCATCATCACCGAGAACGTCCCCTGTGGCACTACGGGCGTCACCTGCTCCAAGGCCATC AAGATCTTCATGGGGAGGACGGAGCTGAAGTTGGAAGACAAGCACCGTGTGGTGATCCAG CGTGATGAGGGTCACCACGTGGCCTACACCACGCGGGAGGTGGGCCAGTACCTGGTGGTG GAGTCCAGCACGGGCATCATCGTCATCTGGGACAAGAGGACCACCGTGTTCATCAAGCTG GCTCCCTCCTACAAGGGCACCGTGTGTGGCCTGTGTGGGAACTTTGACCACCGCTCCAAC AACGACTTCACCACGCGGGACCACATGGTGGTGAGCAGCGAGCTGGACTTCGGGAACAGC TGGAAGGAGGCCCCCACCTGCCCAGATGTGAGCACCAACCCCGAGCCCTGCAGCCTGAAC CCGCACCGCCGCTCCTGGGCCGAGAAGCAGTGCAGCATCCTCAAAAGCAGCGTGTTCAGC ATCTGCCACAGCAAGGTGGACCCCAAGCCCTTCTACGAGGCCTGTGTGCACGACTCGTGC TCCTGTGACACGGGTGGGGACTGTGAGTGCTTCTGCTCTGCCGTGGCCTCCTACGCCCAG GAGTGTACCAAAGAGGGGGCCTGCGTGTTCTGGAGGACGCCGGACCTGTGCCCCATATTC TGCGACTACTACAACCCTCCGCATGAGTGTGAGTGGCACTATGAGCCATGTGGGAACCGG AGCTTCGAGACCTGCAGGACCATCAATGGCATCCACTCCAACATCTCCGTGTCCTACCTG GAGGGCTGCTACCCCCGGTGCCCCAAGGACAGGCCCATCTATGAGGAGGATCTGAAGAAG TGTGTCACTGCAGACAAGTGTGGCTGCTATGTCGAGGACACCCACTACCCACCTGGAGCA TCGGTTCCCACCGAGGAGACCTGCAAGTCCTGCGTGTGTACCAACTCCTCCCAAGTCGTC TGCAGGCCGGAGGAAGGAAAGATTCTTAACCAGACCCAGGATGGCGCCTTCTGCTACTGG GAGATCTGTGGCCCCAACGGGACGGTGGAGAAGCACTTCAACATCTGTTCCATTACGACA CGCCCGTCCACCCTGACCACCTTCACCACCATCACCCTCCCCACCACCCCCACCACCTTC ACCACTACCACCACCACCACCACCCCGACCTCCAGCACAGTTTTATCAACAACTCCGAAG CTGTGCTGCCTCTGGTCTGACTGGATCAATGAGGACCACCCCAGCAGTGGCAGCGACGAC GGTGACCGAGAAACATTTGATGGGGTCTGCGGGGCCCCTGAGGACATCGAGTGCAGGTCG GTCAAGGATCCCCACCTCAGCTTGGAGCAGCTAGGCCAGAAGGTGCAGTGTGATGTCTCT GTTGGGTTCATTTGCAAGAATGAAGACCAGTTTGGAAATGGACCATTTGGACTGTGTTAC GACTACAAGATACGTGTCAATTGTTGCTGGCCCATGGATAAGTGTATCACCACTCCCAGC CCTCCAACTACCACTCCCAGCCCTCCACCAACCAGCACGACCACCCTTCCACCAACCACC ACCCCCAGCCCTCCAACCACCACCACAACCACCCCTCCACCAACCACCACCCCCAGCCCT CCAATAACCACCACGACCACCCCTCCACCAACCACCACTCCCAGCCCTCCAATAAGCACC ACAACCACCCCTCCACCAACCACCACTCCCAGCCCTCCAACCACCACTCCCAGCCCTCCA ACCACCACTCCCAGCCCTCCAACAACCACCACAACCACCCCTCCACCAACCACCACTCCC AGCCCTCCAACGACTACGCCCATCACTCCACCAGCCAGCACTACCACCCTTCCACCAACC ACCACTCCCAGCCCTCCAACAACCACCACAACCACCCCTCCACCAACCACCACTCCCAGT CCTCCAACGACTACGCCCATCACTCCACCAACCAGCACTACTACCCTTCCACCAACCACC ACTCCCAGCCCTCCACCAACCACCACAACCACCCCTCCACCAACCACCACTCCCAGCCCT CCAACAACCACCACTCCCAGTCCTCCAACAATCACCACAACCACCCCTCCACCAACCACC ACTCCCAGCCCTCCAACAACGACCACAACCACCCCTCCACCAACCACCACTCCCAGCCCT CCAACGACTACACCCATCACTCCACCAACCAGCACTACCACCCTTCCACCAACCACCACT CCCAGCCCTCCACCAACCACCACAACCACCCCTCCACCAACCACCACTCCCAGCCCTCCA ACAACCACCACTCCCAGCCCTCCAATAACCACCACAACCACCCCTCCACCAACCACCACT CCCAGCTCTCCAATAACCACCACTCCCAGCCCTCCAACAACCACCATGACCACCCCTTCA CCAACCACCACCCCCAGCTCTCCAATAACCACCACAACCACCCCTTCCTCAACTACCACT CCCAGCCCTCCACCAACCACCATGACCACCCCTTCACCAACCACCACTCCCAGCCCTCCA ACAACCACCATGACCACCCTTCCACCAACCACCACTTCCAGCCCTCTAACAACTACTCCT CTACCTCCATCAATAACTCCTCCTACATTTTCACCATTCTCAACGACAACCCCTACTACC CCATGCGTGCCTCTCTGCAATTGGACTGGCTGGCTGGATTCTGGAAAACCCAACTTTCAC AAACCAGGTGGAGACACAGAATTGATTGGAGACGTCTGTGGACCAGGCTGGGCAGCTAAC ATCTCTTGCAGAGCCACCATGTATCCTGATGTTCCCATTGGACAGCTTGGACAAACAGTG GTGTGTGATGTCTCTGTGGGGCTGATATGCAAAAATGAAGACCAAAAGCCAGGTGGGGTC ATCCCTATGGCCTTCTGCCTCAACTACGAGATCAACGTTCAGTGCTGTGAGTGTGTCACC CAACCCACCACCATGACAACCACCACCACAGAGAACCCAACTCCGCCAACCACGACACCC ATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACC ACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAG ACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACC GGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCA ACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACC CCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACT ACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACC ACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACA CCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCA ACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACA CAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCC ACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACC CCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTG ACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACC ACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATC ACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACG ACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACC CCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGC ACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACA CCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCA ACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACG GTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACC ACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCC ATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACC ACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAG ACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACC GGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCA ACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACC CCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACT ACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACC ACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACA CCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCA ACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACA CAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCC ACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACC CCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTG ACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACC ACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATC ACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACG ACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACC CCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGC ACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACA CCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCA ACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACG GTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACC ACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCC ATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACC ACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAG ACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACC GGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCA ACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACC CCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACT ACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACC ACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACA CCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCA ACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACA CAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCC ACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACC CCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTG ACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACC ACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATC ACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACG ACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACC CCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGC ACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACA CCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCA ACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACG GTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACC ACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCC ATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACC ACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAG ACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACC GGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCA ACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACC CCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACT ACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACC ACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACA CCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCA ACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACA CAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCC ACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACC CCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTG ACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACC ACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATC ACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACG ACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACC CCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGC ACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACA CCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCA ACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACG GTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACC ACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCC ATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACC ACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAG ACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACC GGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCA ACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACC CCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACT ACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACC ACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACA CCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCA ACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACA CAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCC ACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACC CCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTG ACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACC ACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATC ACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACG ACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACC CCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACACCCACCGGC ACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCAACCCCAACA CCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACGGTGACCCCA ACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACCACCACTACG GTGACCCCAACCCCAACACCCACCGGCACACAGACCCCAACCACGACACCCATCACCACC ACCACTACGGTGACCCCAACCCCAACACCCACCGGCACACAGACCGGGCCCCCCACCCAC ACAAGCACAGCACCGATTGCTGAGTTGACCACATCCAATCCTCCGCCTGAGTCCTCAACC CCTCAGACCTCTCGGTCCACCTCTTCCCCTCTCACGGAGTCAACCACCCTTCTGAGTACC CTACCACCTGCCATTGAGATGACCAGCACGGCCCCACCCTCCACACCCACGGCACCCACG ACCACGAGCGGAGGCCACACACTGTCTCCACCGCCCAGCACCACCACGTCCCCTCCAGGC ACCCCCACTCGCGGTACCACGACTGGGTCATCTTCAGCCCCCACCCCCAGCACTGTGCAG ACGACCACCACCAGTGCCTGGACCCCCACGCCGACCCCACTCTCCACACCCAGCATCATC AGGACCACAGGCCTGAGGCCCTACCCTTCCTCTGTGCTTATCTGCTGTGTCCTGAACGAC ACCTACTACGCACCAGGTGAGGAGGTGTACAACGGCACATACGGAGACACCTGTTATTTC GTCAACTGCTCACTGAGCTGTACGTTGGAGTTCTATAACTGGTCCTGCCCATCCACGCCC TCCCCAACACCCACGCCCTCCAAGTCGACGCCCACGCCTTCCAAGCCATCGTCCACGCCC TCCAAGCCGACGCCCGGCACCAAGCCCCCCGAGTGCCCAGACTTTGATCCTCCCAGACAG GAGAACGAGACTTGGTGGCTGTGCGACTGCTTCATGGCCACGTGCAAGTACAACAACACG GTGGAGATCGTGAAGGTGGAGTGTGAGCCGCCGCCCATGCCCACCTGCTCCAACGGCCTC CAACCCGTGCGCGTCGAGGACCCCGACGGCTGCTGCTGGCACTGGGAGTGCGACTGCTAC TGCACGGGCTGGGGCGACCCGCACTATGTCACCTTCGACGGACTCTACTACAGCTACCAG GGCAACTGCACCTACGTGCTGGTGGAGGAGATCAGCCCCTCCGTGGACAACTTCGGAGTT TACATCGACAACTACCACTGCGATCCCAACGACAAGGTGTCCTGCCCCCGCACCCTCATC GTGCGCCACGAGACCCAGGAGGTGCTGATCAAGACCGTGCATATGATGCCCATGCAGGTG CAGGTGCAGGTGAACAGGCAGGCGGTGGCACTGCCCTACAAGAAGTACGGGCTGGAGGTG TACCAGTCTGGCATCAACTACGTGGTGGACATCCCCGAGCTGGGTGTCCTCGTCTCCTAC AATGGCCTGTCCTTCTCCGTCAGGCTGCCCTACCACCGGTTTGGCAACAACACCAAGGGC CAGTGTGGCACCTGCACCAACACCACCTCCGACGACTGCATTCTGCCCAGCGGGGAGATC GTCTCCAACTGTGAGGCTGCGGCTGACCAGTGGCTGGTGAACGACCCCTCCAAGCCACAC TGCCCCCACAGCAGCTCCACGACCAAGCGCCCGGCCGTCACTGTGCCCGGGGGCGGTAAA ACGACCCCACACAAGGACTGCACCCCATCTCCCCTCTGCCAGCTCATCAAGGACAGCCTG TTTGCCCAGTGCCACGCACTGGTGCCCCCGCAGCACTACTACGATGCCTGCGTGTTCGAC AGCTGCTTCATGCCGGGCTCGAGCCTGGAGTGCGCCAGTCTGCAGGCCTACGCAGCCCTC TGTGCCCAGCAGAACATCTGCCTCGACTGGCGGAACCACACGCATGGGGCCTGCTTGGTG GAGTGCCCATCTCACAGGGAGTACCAGGCCTGTGGCCCTGCAGAAGAGCCCACGTGCAAA TCCAGCTCCTCCCAGCAGAACAACACAGTCCTGGTGGAAGGCTGCTTCTGTCCTGAGGGC ACCATGAACTACGCTCCTGGCTTTGATGTCTGCGTGAAGACCTGCGGCTGTGTGGGACCT GACAATGTGCCCAGAGAGTTTGGGGAGCACTTCGAGTTCGACTGCAAGAACTGTGTCTGC CTGGAGGGTGGAAGTGGCATCATCTGCCAACCCAAGAGGTGCAGCCAGAAGCCCGTTACC CACTGCGTGGAAGACGGCACCTACCTCGCCACGGAGGTCAACCCTGCCGACACCTGCTGC AACATTACCGTCTGCAAGTGCAACACCAGCCTGTGCAAAGAGAAGCCCTCCGTGTGCCCG CTGGGATTCGAAGTGAAGAGCAAGATGGTGCCTGGAAGGTGCTGTCCTTTCTACTGGTGT GAGTCCAAGGGGGTGTGTGTTCACGGGAATGCTGAGTACCAGCCCGGTTCTCCAGTTTAT TCCTCCAAGTGCCAGGACTGCGTGTGCACGGACAAGGTGGACAACAACACCCTGCTCAAC GTCATCGCCTGCACCCACGTGCCCTGCAACACCTCCTGCAGCCCTGGCTTCGAACTCATG GAGGCCCCCGGGGAGTGCTGTAAGAAGTGTGAACAGACGCACTGTATCATCAAACGGCCC GACAACCAGCACGTCATCCTGAAGCCCGGGGACTTCAAGAGCGACCCGAAGAACAACTGC ACATTCTTCAGCTGCGTGAAGATCCACAACCAGCTCATCTCGTCCGTCTCCAACATCACC TGCCCCAACTTTGATGCCAGCATTTGCATCCCGGGCTCCATCACATTCATGCCCAATGGA TGCTGCAAGACCTGCACCCCTCGCAATGAGACCAGGGTGCCCTGCTCCACCGTCCCCGTC ACCACGGAGGTTTCGTACGCCGGCTGCACCAAGACCGTCCTCATGAATCATTGCTCCGGG TCCTGCGGGACATTTGTCATGTACTCGGCCAAGGCCCAGGCCCTGGACCACAGCTGCTCC TGCTGCAAAGAGGAGAAAACCAGCCAGCGTGAGGTGGTCCTGAGCTGCCCCAATGGCGGC TCGCTGACACACACCTACACCCACATCGAGAGCTGCCAGTGCCAGGACACCGTCTGCGGG CTCCCCACCGGCACCTCCCGCCGGGCCCGGCGCTCCCCTAGGCATCTGGGGAGCGGGTGA
- Chromosome Location
- 11
- Locus
- 11p15.5
- External Identifiers
Resource Link UniProtKB ID Q02817 UniProtKB Entry Name MUC2_HUMAN GenBank Protein ID 454154 GenBank Gene ID L21998 GeneCard ID MUC2 GenAtlas ID MUC2 HGNC ID HGNC:7512 PDB ID(s) 6RBF, 6TM2, 6TM6, 7A5O, 7POV, 7PP6, 7PRL, 7QCL, 7QCN, 7QCU, 8CK2, 8S03 KEGG ID hsa:4583 NCBI Gene ID 4583 - General References
- Gum JR Jr, Hicks JW, Toribara NW, Siddiki B, Kim YS: Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor. J Biol Chem. 1994 Jan 28;269(4):2440-6. [Article]
- Gum JR Jr, Hicks JW, Toribara NW, Rothe EM, Lagace RE, Kim YS: The human MUC2 intestinal mucin has cysteine-rich subdomains located both upstream and downstream of its central repetitive region. J Biol Chem. 1992 Oct 25;267(30):21375-83. [Article]
- Toribara NW, Gum JR Jr, Culhane PJ, Lagace RE, Hicks JW, Petersen GM, Kim YS: MUC-2 human small intestinal mucin gene structure. Repeated arrays and polymorphism. J Clin Invest. 1991 Sep;88(3):1005-13. [Article]
- Gum JR, Byrd JC, Hicks JW, Toribara NW, Lamport DT, Kim YS: Molecular cloning of human intestinal mucin cDNAs. Sequence analysis and evidence for genetic polymorphism. J Biol Chem. 1989 Apr 15;264(11):6480-7. [Article]
- Xu G, Huan L, Khatri I, Sajjan US, McCool D, Wang D, Jones C, Forstner G, Forstner J: Human intestinal mucin-like protein (MLP) is homologous with rat MLP in the C-terminal region, and is encoded by a gene on chromosome 11 p 15.5. Biochem Biophys Res Commun. 1992 Mar 16;183(2):821-8. [Article]
- Silverman HS, Parry S, Sutton-Smith M, Burdick MD, McDermott K, Reid CJ, Batra SK, Morris HR, Hollingsworth MA, Dell A, Harris A: In vivo glycosylation of mucin tandem repeats. Glycobiology. 2001 Jun;11(6):459-71. [Article]
- Godl K, Johansson ME, Lidell ME, Morgelin M, Karlsson H, Olson FJ, Gum JR Jr, Kim YS, Hansson GC: The N terminus of the MUC2 mucin forms trimers that are held together within a trypsin-resistant core fragment. J Biol Chem. 2002 Dec 6;277(49):47248-56. Epub 2002 Oct 8. [Article]
- Lidell ME, Johansson ME, Hansson GC: An autocatalytic cleavage in the C terminus of the human MUC2 mucin occurs at the low pH of the late secretory pathway. J Biol Chem. 2003 Apr 18;278(16):13944-51. Epub 2003 Feb 11. [Article]
- Dephoure N, Zhou C, Villen J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP: A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10762-7. doi: 10.1073/pnas.0805139105. Epub 2008 Jul 31. [Article]
- Park SW, Zhen G, Verhaeghe C, Nakagami Y, Nguyenvu LT, Barczak AJ, Killeen N, Erle DJ: The protein disulfide isomerase AGR2 is essential for production of intestinal mucus. Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6950-5. doi: 10.1073/pnas.0808722106. Epub 2009 Apr 9. [Article]
- Johansson ME, Thomsson KA, Hansson GC: Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein. J Proteome Res. 2009 Jul;8(7):3549-57. doi: 10.1021/pr9002504. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Pranlukast investigational unknown target other/unknown Details Colforsin experimental, investigational unknown target activator Details