Penicillin-binding protein 2
Details
- Name
- Penicillin-binding protein 2
- Kind
- protein
- Synonyms
- penA
- Sporulation-specific penicillin-binding protein
- spoVD
- Gene Name
- pbpA
- UniProtKB Entry
- Q9X6V3TrEMBL
- Organism
- Pseudomonas aeruginosa
- NCBI Taxonomy ID
- 287
- Amino acid sequence
>lcl|BSEQ0022345|Penicillin-binding protein 2 MPQPIHLKDHEKDARLVRRRVIVGAVAVVLLTLVLVARMYHLQVTQYEYHSTLSENNRVH VQPIPPTRGIIFDRNGVIIADNRPSFSLTITRERTEDLQKTLDTLVEILGLTEDDRAIFE KRMKQGRRPFEPVPIMFELNEEQIARIAVNQFRLPGVDVATQFVRHYPLKEHFAHSVGYV GRINEQELKNLDPINYSGTHHIGKTGIERFYESELHGTVGYEEVETNARGRVLRVLKRTD PIPGKDIVLSIDSRLQEAAENALAGRRGAIVAIQPSTGDVLAMVSQPSYDPNLFVTGISF KAYAELRDSIDRPLYNRVLRGLYPPGSTVKPAVALAGLDAGVVTPTSRVFDPGYYQLPNY DHKYRNWNRYGDGWVSLESAIYRSNDTYFYDLAHKLGIDRLHAFMSRFGFGQKVALDMFG EADGLMPSREWKRKTRRQVWYPGETLILGIGQGYMQATPIQLAQMTALLANKGHWIRPHL AKTIDGQPPVDPDPMPDIVLRDPANWDRVDYGMQQVVHGARGTARKVGATSAYLIAGKSG TAQVVAIKQNERYDRSKLLERHRDHALFVGFAPANNPQIAVAVMVENGESGSGVAAPVVK QVMDAWLLDEHGKLKAEYAEPVAPLAAAVAKPEPTAAEPEAPALEQ
- Number of residues
- 646
- Molecular Weight
- 72212.855
- Theoretical pI
- Not Available
- GO Classification
- Functionspenicillin bindingComponentsintegral component of membrane
- General Function
- Catalyzes cross-linking of the peptidoglycan cell wall.
- Specific Function
- penicillin binding
- Pfam Domain Function
- Signal Regions
- Not Available
- Transmembrane Regions
- 21-40
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0022346|Penicillin-binding protein 2 (pbpA) ATGCCGCAGCCGATCCACCTGAAAGACCACGAGAAAGACGCCCGCCTGGTGCGTCGGCGC GTCATCGTCGGGGCGGTGGCGGTGGTCTTGCTGACCCTGGTGCTGGTGGCGCGCATGTAC CACCTGCAGGTGACCCAGTACGAGTACCATTCGACGCTGTCGGAGAACAACCGGGTCCAT GTGCAGCCGATCCCGCCGACCCGCGGGATCATCTTCGACCGCAACGGCGTGATCATCGCC GACAACCGGCCGAGCTTCAGCCTGACCATCACCCGCGAACGCACCGAGGACCTGCAGAAG ACCCTCGACACGCTGGTGGAGATCCTCGGCCTGACCGAGGACGACCGGGCCATCTTCGAG AAGCGCATGAAGCAGGGGCGGCGTCCGTTCGAGCCGGTTCCCATCATGTTCGAACTCAAC GAGGAACAGATCGCCCGCATCGCGGTGAACCAGTTCCGCCTGCCGGGCGTCGACGTGGCG ACCCAGTTCGTCCGCCACTACCCGCTGAAGGAGCACTTCGCCCATTCGGTCGGGTACGTC GGGCGGATCAACGAGCAGGAACTGAAGAACCTCGACCCGATTAACTACAGCGGCACCCAC CATATCGGCAAGACCGGCATCGAGCGCTTCTACGAGAGCGAGTTGCACGGCACGGTTGGC TACGAGGAAGTCGAGACCAACGCCCGCGGGCGGGTGCTGCGGGTGCTCAAGCGCACCGAC CCGATTCCCGGCAAGGACATCGTCCTGAGCATCGACAGCCGCCTGCAGGAGGCCGCCGAG AACGCCCTGGCCGGGCGGCGGGGCGCCATCGTGGCGATCCAGCCGTCCACCGGCGACGTG CTGGCGATGGTCAGCCAGCCGAGCTACGACCCCAACCTGTTCGTCACCGGCATCAGCTTC AAGGCCTATGCCGAGCTGCGTGACTCCATCGACCGGCCGCTGTACAACCGCGTCCTGCGC GGGCTCTATCCGCCGGGCTCGACGGTGAAGCCGGCGGTGGCGCTGGCCGGCCTCGACGCC GGGGTGGTCACGCCGACCTCGCGGGTCTTCGACCCCGGCTACTACCAGTTGCCCAACTAC GACCACAAGTACCGTAACTGGAACCGCTACGGCGATGGCTGGGTGAGCCTGGAGTCGGCG ATCTACCGGTCCAACGACACCTATTTCTACGACCTCGCGCACAAGCTGGGGATCGACCGC CTGCACGCCTTCATGAGCCGCTTCGGCTTCGGCCAGAAAGTCGCCCTGGACATGTTCGGC GAAGCCGACGGGCTGATGCCCTCGCGCGAATGGAAGCGCAAGACCCGCCGCCAGGTCTGG TACCCGGGCGAGACCCTGATCCTCGGCATCGGCCAGGGCTACATGCAGGCGACGCCGATC CAACTGGCGCAGATGACCGCGCTGCTGGCCAACAAGGGCCACTGGATCCGCCCGCACCTG GCCAAGACCATCGACGGCCAGCCGCCGGTCGACCCCGACCCGATGCCCGACATCGTGCTG CGCGACCCGGCCAACTGGGACCGCGTCGACTACGGCATGCAGCAGGTGGTGCATGGCGCC CGCGGCACGGCGCGCAAGGTCGGCGCCACCTCGGCCTACCTGATCGCCGGCAAGAGCGGT ACCGCCCAGGTGGTGGCGATCAAGCAGAACGAGCGCTACGACCGCTCCAAGCTGCTCGAG CGGCACCGCGACCACGCCCTGTTCGTCGGCTTCGCGCCGGCCAACAACCCGCAGATCGCG GTGGCGGTGATGGTGGAGAACGGCGAGTCCGGCTCCGGCGTCGCCGCCCCGGTGGTCAAG CAGGTGATGGACGCCTGGCTGCTCGACGAGCACGGCAAGCTCAAGGCCGAATACGCGGAA CCCGTCGCGCCGCTCGCGGCGGCGGTGGCCAAGCCCGAACCCACGGCAGCCGAGCCGGAG GCGCCCGCCCTTGAACAGTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9X6V3 UniProtKB Entry Name Q9X6V3_PSEAI KEGG ID pae:PA4003 NCBI Gene ID 878962 - General References
- Not Available
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Cefepime approved, investigational unknown target inhibitor Details Cefiderocol approved, investigational yes target inhibitor Details