60S ribosomal protein L27
Details
- Name
- 60S ribosomal protein L27
- Kind
- protein
- Synonyms
- 60S ribosomal protein L27, putative
- Gene Name
- Not Available
- UniProtKB Entry
- Q8IKM5TrEMBL
- Organism
- Plasmodium falciparum (isolate 3D7)
- NCBI Taxonomy ID
- 36329
- Amino acid sequence
>lcl|BSEQ0051432|60S ribosomal protein L27 MGKLLKPGKVIIILNGRRAGKKAVIVNTYEGQTRERPYSYCLVAGIEKHPLKVNKSMTKK KIVKRSKVKAFIKCINVNHILPTRYQVANDFDIKSLASDDVLKSKNKKKEVKKLGKIFRD KFLEPVNKKTGEVSKDISFLHKKLYF
- Number of residues
- 146
- Molecular Weight
- 16744.955
- Theoretical pI
- Not Available
- GO Classification
- Functionsstructural constituent of ribosomeProcessestranslationComponentscytosolic large ribosomal subunit
- General Function
- Not Available
- Specific Function
- Structural constituent of ribosome
- Pfam Domain Function
- Ribosomal_L27e (PF01777)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0051433|60S ribosomal protein L27 ATGGGAAAATTATTGAAACCAGGAAAAGTTATCATAATATTAAACGGTCGTAGAGCTGGA AAAAAGGCTGTCATAGTAAACACTTATGAAGGTCAAACCCGTGAAAGACCATATAGTTAC TGCTTAGTAGCTGGTATAGAAAAACATCCATTAAAAGTTAACAAAAGTATGACCAAGAAA AAAATCGTAAAAAGATCAAAAGTTAAGGCCTTTATAAAATGTATTAACGTAAATCACATC CTTCCAACAAGATACCAAGTAGCTAATGATTTCGATATTAAAAGTTTAGCATCTGATGAT GTCTTGAAATCCAAAAATAAAAAGAAGGAAGTAAAAAAATTGGGAAAAATATTTAGAGAC AAATTTTTGGAACCAGTTAACAAAAAAACCGGAGAGGTTTCCAAGGATATTTCCTTCTTA CACAAAAAGTTGTACTTTTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q8IKM5 UniProtKB Entry Name Q8IKM5_PLAF7 PDB ID(s) 3J79, 3JBN, 3JBO, 3JBP, 5UMD KEGG ID pfa:PF14_0579 NCBI Gene ID 812161 - General References
- Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B: Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002 Oct 3;419(6906):498-511. [Article]
- Wong W, Bai XC, Brown A, Fernandez IS, Hanssen E, Condron M, Tan YH, Baum J, Scheres SH: Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife. 2014 Jun 9;3. doi: 10.7554/eLife.03080. [Article]
- Sun M, Li W, Blomqvist K, Das S, Hashem Y, Dvorin JD, Frank J: Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Res. 2015 Dec 2;43(21):10515-24. doi: 10.1093/nar/gkv991. Epub 2015 Oct 1. [Article]
- Wong W, Bai XC, Sleebs BE, Triglia T, Brown A, Thompson JK, Jackson KE, Hanssen E, Marapana DS, Fernandez IS, Ralph SA, Cowman AF, Scheres SHW, Baum J: Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis. Nat Microbiol. 2017 Mar 13;2:17031. doi: 10.1038/nmicrobiol.2017.31. [Article]