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Target Identification Data Package
This package has 11 modules. The Structured Pharmacology Module has 11 tables. Preview the first five rows of each table or Explore the schema
Structured Pharmacology Module
11 Tables
The Structured Pharmacology Module provides essential pharmacokinetic parameters: LD50, Clearance, Half-Life, Volume of Distribution, Bioavailability, AUC, Cmax, Tmax, and Protein Binding.
id | drug_id | value | min | max | unit | fda_label_reference | msds_reference | organism_id | dosage_route_id |
|---|---|---|---|---|---|---|---|---|---|
3 | 8920 | 300.0 | mg/kg | 1 | 1 | 1582 | 84 | ||
6 | 40 | 39.0 | mg/kg | 0 | 0 | 1579 | 70 | ||
9 | 73 | 27.0 | mg/kg | 1 | 1 | 1582 | 84 | ||
12 | 73 | 32.0 | mg/m³ | 1 | 1 | 1582 | 93 | ||
15 | 73 | 37.0 | mg/m³ | 1 | 1 | 1579 | 93 |
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id | drug_id | value | min | max | unit | normalized_value | normalized_min | normalized_max | normalized_unit | dosage_route_id | dosage_form_id | dose_value | dose_min | dose_max | dose_unit | normalized_dose_value | normalized_dose_min | normalized_dose_max | normalized_dose_unit | fda_label_reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7 | 1 | 139.0 | mL/min | 8.34 | L/h | 0 | ||||||||||||||
12 | 1 | 61.0 | mL/min | 3.66 | L/h | 0 | ||||||||||||||
17 | 1 | 114.0 | mL/min | 6.84 | L/h | 0 | ||||||||||||||
22 | 6 | 3.4 | mL/min/kg | 0.204 | L/h/kg | 0 | ||||||||||||||
27 | 6 | 2.7 | mL/min/kg | 0.162 | L/h/kg | 0 |
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id | drug_id | value | min | max | unit | normalized_value | normalized_min | normalized_max | normalized_unit | dosage_route_id | dosage_form_id | dose_value | dose_min | dose_max | dose_unit | normalized_dose_value | normalized_dose_min | normalized_dose_max | normalized_dose_unit | fda_label_reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
8998 | 4 | 70.0 | 80.0 | minutes | 1.166666667 | 1.333333333 | h | 0 | ||||||||||||
9003 | 8 | 164.0 | 84.0 | 353.0 | hours | 164.0 | 84.0 | 353.0 | h | 1 | ||||||||||
9008 | 16 | 4.0 | hours | 4.0 | h | 70 | 65 | 1 | ||||||||||||
9013 | 16 | 6.0 | hours | 6.0 | h | 70 | 65 | 1 | ||||||||||||
9018 | 16 | 4.0 | 13.0 | hours | 4.0 | 13.0 | h | 70 | 65 | 1 |
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id | drug_id | value | min | max | unit | normalized_value | normalized_min | normalized_max | normalized_unit | dosage_route_id | dosage_form_id | dose_value | dose_min | dose_max | dose_unit | normalized_dose_value | normalized_dose_min | normalized_dose_max | normalized_dose_unit | fda_label_reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
27463 | 5084 | 50.0 | L | 50.0 | L | 0 | ||||||||||||||
27468 | 1281 | 0.07 | L/kg | 0.07 | L/kg | 70 | 0 | |||||||||||||
27473 | 1281 | 0.09 | L/kg | 0.09 | L/kg | 70 | 0 | |||||||||||||
27478 | 1281 | 0.11 | L/kg | 0.11 | L/kg | 98 | 0 | |||||||||||||
27483 | 15619 | 100.0 | L | 100.0 | L | 70 | 0 |
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id | drug_id | value | min | max | unit | normalized_value | normalized_min | normalized_max | normalized_unit | dosage_route_id | dosage_form_id | dose_value | dose_min | dose_max | dose_unit | normalized_dose_value | normalized_dose_min | normalized_dose_max | normalized_dose_unit | fda_label_reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
23323 | 17 | 71.0 | % | 71.0 | % | 98 | 0 | |||||||||||||
23328 | 17 | 66.0 | % | 66.0 | % | 50 | 0 | |||||||||||||
23333 | 17 | 3.0 | 5.0 | % | 3.0 | 5.0 | % | 58 | 0 | |||||||||||
23338 | 26 | 95.0 | % | 95.0 | % | 98 | 65 | 70.0 | mg | 70.0 | mg | 0 | ||||||||
23343 | 38 | 80.0 | % | 80.0 | % | 0 |
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id | drug_id | value | min | max | unit | normalized_value | normalized_min | normalized_max | normalized_unit | dosage_route_id | dosage_form_id | dose_value | dose_min | dose_max | dose_unit | normalized_dose_value | normalized_dose_min | normalized_dose_max | normalized_dose_unit | fda_label_reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
35073 | 1 | 2500.0 | ng•h/mL | 2.5 | mg.h/L | 70 | 65 | 0.4 | mg/kg | 0.4 | mg/kg | 0 | ||||||||
35078 | 1 | 612.0 | ng•h/mL | 0.612 | mg.h/L | 70 | 65 | 0.1 | mg/kg | 0.1 | mg/kg | 0 | ||||||||
35083 | 1 | 1184.0 | ng•h/mL | 1.184 | mg.h/L | 70 | 65 | 0.15 | mg/kg | 0.15 | mg/kg | 0 | ||||||||
35088 | 1 | 1446.0 | ng•h/mL | 1.446 | mg.h/L | 70 | 65 | 0.2 | mg/kg | 0.2 | mg/kg | 0 | ||||||||
35093 | 46 | 2360.0 | 2390.0 | pmol hr/L | 0.0000000024 | 0.0000000024 | mol.h/L | 98 | 0 |
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id | drug_id | value | min | max | unit | normalized_value | normalized_min | normalized_max | normalized_unit | dosage_route_id | dosage_form_id | dose_value | dose_min | dose_max | dose_unit | normalized_dose_value | normalized_dose_min | normalized_dose_max | normalized_dose_unit | fda_label_reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
40328 | 1 | 2924.0 | ng/mL | 2.924 | mg/L | 70 | 65 | 0.4 | mg/kg | 0.4 | mg/kg | 0 | ||||||||
40333 | 1 | 111.0 | ng/mL | 0.111 | mg/L | 70 | 65 | 0.1 | mg/kg | 0.1 | mg/kg | 0 | ||||||||
40338 | 1 | 203.0 | ng/mL | 0.203 | mg/L | 70 | 65 | 0.15 | mg/kg | 0.15 | mg/kg | 0 | ||||||||
40343 | 1 | 2446.0 | ng/mL | 2.446 | mg/L | 70 | 65 | 0.2 | mg/kg | 0.2 | mg/kg | 0 | ||||||||
40348 | 5 | 1.1 | mcg/L | 0.0011 | mg/L | 98 | 25.0 | mg | 25.0 | mg | 0 |
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id | drug_id | value | min | max | unit | normalized_value | normalized_min | normalized_max | normalized_unit | dosage_route_id | dosage_form_id | dose_value | dose_min | dose_max | dose_unit | normalized_dose_value | normalized_dose_min | normalized_dose_max | normalized_dose_unit | fda_label_reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
36733 | 1 | 0.17 | hours | 0.17 | h | 70 | 65 | 0.4 | mg/kg | 0.4 | mg/kg | 0 | ||||||||
36738 | 5 | 69.0 | h | 69.0 | h | 98 | 25.0 | mg | 25.0 | mg | 0 | |||||||||
36743 | 16 | 20.0 | 25.0 | hours | 20.0 | 25.0 | h | 98 | 1 | |||||||||||
36748 | 16 | 5.0 | 24.0 | hours | 5.0 | 24.0 | h | 98 | 1 | |||||||||||
36753 | 19 | 1.0 | 2.0 | days | 24.0 | 48.0 | h | 98 | 0 |
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id | drug_id | value | min | max | unit | normalized_value | normalized_min | normalized_max | normalized_unit | dosage_route_id | dosage_form_id | dose_value | dose_min | dose_max | dose_unit | normalized_dose_value | normalized_dose_min | normalized_dose_max | normalized_dose_unit | fda_label_reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3782 | 1 | 3.0 | % | 3.0 | % | 0 | ||||||||||||||
3787 | 7 | 43.0 | 49.0 | % | 43.0 | 49.0 | % | 0 | ||||||||||||
3792 | 14 | 27.3 | % | 27.3 | % | 0 | ||||||||||||||
3797 | 17 | 30.0 | 40.0 | % | 30.0 | 40.0 | % | 0 | ||||||||||||
3802 | 35 | 17.3 | % | 17.3 | % | 0 |
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structured_pharmacology_protein_binding_id | bio_entity_id |
|---|---|
3822 | BE0000530 |
3827 | BE0000925 |
3862 | BE0001141 |
3902 | BE0000530 |
3987 | BE0000530 |
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id | drug_id | value | min | max | unit | normalized_value | normalized_min | normalized_max | normalized_unit | dosage_route_id | dosage_form_id | dose_value | dose_min | dose_max | dose_unit | normalized_dose_value | normalized_dose_min | normalized_dose_max | normalized_dose_unit | fda_label_reference | importance | elimination_type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5662 | 1 | 48.3 | % | 48.3 | % | 0 | Unspecified | Urine | ||||||||||||||
5667 | 7 | 0.0 | 5.0 | % | 0.0 | 5.0 | % | 3.75 | mg | 3.75 | mg | 0 | Minor | Urine | ||||||||
5672 | 9 | 80.0 | % | 80.0 | % | 0 | Major | Urine | ||||||||||||||
5677 | 13 | % | 0 | Unspecified | Urine | |||||||||||||||||
5682 | 13 | % | 0 | Unspecified | Feces |
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Showing 11 of 11 tables