Streptococcus pneumoniae type 18C capsular polysaccharide diphtheria CRM197 protein conjugate antigen
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Identification
- Brand Names
- Prevnar 13, Prevnar 20, Vaxneuvance
- Generic Name
- Streptococcus pneumoniae type 18C capsular polysaccharide diphtheria CRM197 protein conjugate antigen
- DrugBank Accession Number
- DB10290
- Background
Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 18c individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F for intramuscular injection. The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein carrier CRM197 to form the glycoconjugate.
- Type
- Biotech
- Groups
- Approved
- Biologic Classification
- Vaccines
Conjugate - Synonyms
- Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Prevention of Infection caused by streptococcus pneumoniae serotype 18c •••••••••••• Prevention of Otitis media caused by streptococcus pneumoniae serotype 18c •••••••••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
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- Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image PREVENAR 0.5 ML ENJEKSIYON ICIN SUSPANSIYON ICEREN KULL.HAZ.ENJEKTOR, 1 ADET Streptococcus pneumoniae type 18C capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2 μg) + Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2 μg) + Streptococcus pneumoniae type 19F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2 μg) + Streptococcus pneumoniae type 23F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2 μg) + Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2 μg) + Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen (4 μg) + Streptococcus pneumoniae type 9V capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2 μg) Suspension Intramuscular PFİZER İLAÇLARI LTD. ŞTİ. 2008-07-25 2022-04-11 Turkey 
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- XK87D9J012
- CAS number
- Not Available
References
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample dataNot Available Completed Not Available Acellular Pertussis / Diphtheria / Poliomyelitis / Tetanus / Viral Hepatitis B 1 somestatus stop reason just information to hide Not Available Completed Not Available Invasive Pneumococcal Disease (IPD) 1 somestatus stop reason just information to hide Not Available Completed Not Available Multiple Myeloma (MM) 1 somestatus stop reason just information to hide Not Available Completed Not Available Pneumococcal Infection 1 somestatus stop reason just information to hide Not Available Completed Basic Science Pneumococcal Infection 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, suspension Intramuscular Suspension Intramuscular - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at December 01, 2015 20:03 / Updated at August 13, 2021 20:47