This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Summary
Potassium guaiacolsulfonate is a mucolytic and expectorant indicated to relieve a productive cough.
- Generic Name
- Potassium guaiacolsulfonate
- DrugBank Accession Number
- DB13735
- Background
Guaiacolsulfonate is an aromatic sulfonic acid. Potassium guaiacolsulfonate salt is an expectorant that thins the mucus in the lungs and reduces chest congestion.
- Type
- Small Molecule
- Groups
- Approved, Experimental
- Synonyms
- Guaiacolsulfonate potassium
- Potassium sulfoguaiacolate
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination to treat Allergic cough Combination Product in combination with: Dextromethorphan (DB00514), Chlorpheniramine (DB01114) •••••••••••• ••••••• •••••• Used in combination to treat Cough caused by common cold Combination Product in combination with: Dextromethorphan (DB00514), Chlorpheniramine (DB01114) •••••••••••• ••••••• •••••• Used in combination for symptomatic treatment of Coughing Combination Product in combination with: Dextromethorphan (DB00514) ••• ••• ••••• Used in combination for symptomatic treatment of Coughing Combination Product in combination with: Dropropizine (DB13785) ••• ••• ••••• Used in combination to treat Coughing Combination Product in combination with: Sodium citrate (DB09154) ••• ••• ••••• - Associated Therapies
- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcebutolol Potassium guaiacolsulfonate may increase the hyperkalemic activities of Acebutolol. Aceclofenac Potassium guaiacolsulfonate may increase the hyperkalemic activities of Aceclofenac. Acemetacin Potassium guaiacolsulfonate may increase the hyperkalemic activities of Acemetacin. Acetylsalicylic acid Potassium guaiacolsulfonate may increase the hyperkalemic activities of Acetylsalicylic acid. Alclofenac Potassium guaiacolsulfonate may increase the hyperkalemic activities of Alclofenac. - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Active Moieties
Name Kind UNII CAS InChI Key Potassium cation ionic 295O53K152 24203-36-9 NPYPAHLBTDXSSS-UHFFFAOYSA-N - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Ambenyl Cough Syrup Potassium guaiacolsulfonate (80 mg / 5 mL) + Ammonium chloride (80 mg / 5 mL) + Bromodiphenhydramine hydrochloride (3.75 mg / 5 mL) + Codeine phosphate (10 mg / 5 mL) + Diphenhydramine hydrochloride (8.75 mg / 5 mL) Liquid Oral Parke Davis Division, Warner Lambert Canada Inc. 1979-12-31 1997-08-25 Canada 
ANTIBEKSIN SURUP, 100 ML Potassium guaiacolsulfonate (175 mg/5ml) + Ephedrine hydrochloride (5 mg/5ml) + Pheniramine maleate (15 mg/5ml) + Sodium citrate (65 mg/5ml) Syrup Oral YAVUZ İLAÇ ECZA DEPOSU MEDİKAL ÜRÜNLER SAN.VE TİC. A.Ş. 2009-02-06 Not applicable Turkey 
ARTU 100 ML SURUP Potassium guaiacolsulfonate (175 mg/5ml) + Sodium benzoate (5 mg/5ml) + Ephedrine hydrochloride (5 mg/5ml) + Promethazine hydrochloride (5 mg/5ml) Syrup Oral GÜNSA GÜNEY İLAÇ VE HAMMADDELER SAN. VE TİC. A.Ş. 1972-03-16 Not applicable Turkey BENACOL DTM Potassium guaiacolsulfonate (30 mg) + Ammonium chloride (100 mg) + Dextromethorphan hydrobromide (7.5 mg) + Diphenhydramine hydrochloride (12.5 mg) Syrup Oral Dankos Farma 2015-12-21 2024-11-22 Indonesia 
BENACOL EXPECTORANT Potassium guaiacolsulfonate (30 mg/mL) + Ammonium chloride (100 mg/5mL) + Diphenhydramine hydrochloride (12.5 mg/5mL) Syrup Oral Dankos Farma 2018-12-31 2023-10-31 Indonesia - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image P-Tuss Potassium guaiacolsulfonate (300 mg/5mL) + Hydrocodone bitartrate (5 mg/5mL) Liquid Oral Prasco, Laboratories 2010-12-01 2011-01-21 US 
Phenylephrine Carbetapentane Potassium Guaiacolsulfonate Potassium guaiacolsulfonate (100 mg/5mL) + Pentoxyverine (20 mg/5mL) + Phenylephrine (10 mg/5mL) Liquid Oral River's Edge Pharmaceuticals, LLC 2010-03-01 2010-11-20 US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 21A795TNZD
- CAS number
- 1321-14-8
References
- General References
- AIFA Package Leaflet: CORYFIN SEDATIVO FLUIDIFICANTE (dextromethorphan and potassium guaiacolsulfonate) oral syrup [Link]
- External Links
- PubChem Substance
- 347911449
- 91275
- Wikipedia
- Guaiacolsulfonate
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Syrup Oral 7.5 mg Suspension Solution / drops Buccal Suspension 1 mg/5mL Suspension 1.067 mg/5mL Syrup Oral 100 mg/5mL Liquid Oral Syrup Oral 44 mg Syrup Oral Syrup Tablet, sugar coated Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at June 23, 2017 20:47 / Updated at May 08, 2024 08:09