This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Perphenazine enanthate
- DrugBank Accession Number
- DB14651
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Perphenazine enanthate (DB14651)
- Weight
- Average: 516.14
Monoisotopic: 515.2373263 - Chemical Formula
- C28H38ClN3O2S
- Synonyms
- Perphenazine enantate
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your software1,2-Benzodiazepine The risk or severity of CNS depression can be increased when 1,2-Benzodiazepine is combined with Perphenazine enanthate. Acebutolol The serum concentration of Acebutolol can be increased when it is combined with Perphenazine enanthate. Acetazolamide The risk or severity of CNS depression can be increased when Acetazolamide is combined with Perphenazine enanthate. Acetohexamide The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Perphenazine enanthate. Acetophenazine The risk or severity of CNS depression can be increased when Acetophenazine is combined with Perphenazine enanthate. - Food Interactions
- Not Available
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as phenothiazines. These are polycyclic aromatic compounds containing a phenothiazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a para-thiazine ring.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Benzothiazines
- Sub Class
- Phenothiazines
- Direct Parent
- Phenothiazines
- Alternative Parents
- Alkyldiarylamines / Diarylthioethers / Fatty acid esters / N-alkylpiperazines / 1,4-thiazines / Benzenoids / Aryl chlorides / Trialkylamines / Carboxylic acid esters / Amino acids and derivatives show 7 more
- Substituents
- 1,4-diazinane / Alkyldiarylamine / Amine / Amino acid or derivatives / Aromatic heteropolycyclic compound / Aryl chloride / Aryl halide / Aryl thioether / Azacycle / Benzenoid show 24 more
- Molecular Framework
- Aromatic heteropolycyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Z6RS3DKN8J
- CAS number
- 17528-28-8
- InChI Key
- PWEGQJCIAMJJHC-UHFFFAOYSA-N
- InChI
- InChI=1S/C28H38ClN3O2S/c1-2-3-4-5-11-28(33)34-21-20-31-18-16-30(17-19-31)14-8-15-32-24-9-6-7-10-26(24)35-27-13-12-23(29)22-25(27)32/h6-7,9-10,12-13,22H,2-5,8,11,14-21H2,1H3
- IUPAC Name
- 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethyl heptanoate
- SMILES
- CCCCCCC(=O)OCCN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(Cl)C=C3)CC1
References
- General References
- Not Available
- External Links
- PubChem Compound
- 23623915
- ChemSpider
- 56601
- ZINC
- ZINC000030691684
- Wikipedia
- Perphenazine
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.000557 mg/mL ALOGPS logP 6.41 ALOGPS logP 6.61 Chemaxon logS -6 ALOGPS pKa (Strongest Basic) 7.48 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 36.02 Å2 Chemaxon Rotatable Bond Count 13 Chemaxon Refractivity 148.28 m3·mol-1 Chemaxon Polarizability 59.95 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 223.58284 predictedDeepCCS 1.0 (2019) [M+H]+ 226.04222 predictedDeepCCS 1.0 (2019) [M+Na]+ 233.40285 predictedDeepCCS 1.0 (2019)
Drug created at September 01, 2018 23:43 / Updated at June 12, 2020 16:53