Sonrotoclax
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Sonrotoclax
- DrugBank Accession Number
- DB18753
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 890.11
Monoisotopic: 889.419668442 - Chemical Formula
- C49H59N7O7S
- Synonyms
- N-[4-({[(1r,4r)-4-hydroxy-4-methylcyclohexyl]methyl}amino)-3- nitrobenzene-1-sulfonyl]-4-(2-{(2S)-2-[2-(propan-2-yl)phenyl]pyrrolidin- 1-yl}-7-azaspiro[3.5]nonan-7-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-5- yl)oxy]benzamide
- External IDs
- BGB 11417
- BGB-11417
- BGB11417
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 30R67U9KYS
- CAS number
- 2383086-06-2
- InChI Key
- ZQTKOYMWCCSKON-XKXNWSITSA-N
- InChI
- InChI=1S/C49H59N7O7S/c1-32(2)39-7-4-5-8-40(39)43-9-6-22-55(43)36-28-49(29-36)19-23-54(24-20-49)35-10-12-41(45(26-35)63-37-25-34-16-21-50-46(34)52-31-37)47(57)53-64(61,62)38-11-13-42(44(27-38)56(59)60)51-30-33-14-17-48(3,58)18-15-33/h4-5,7-8,10-13,16,21,25-27,31-33,36,43,51,58H,6,9,14-15,17-20,22-24,28-30H2,1-3H3,(H,50,52)(H,53,57)/t33-,43-,48+/m0/s1
- IUPAC Name
- SMILES
- CC(C)C1=CC=CC=C1[C@@H]1CCCN1C1CC2(C1)CCN(CC2)C1=CC=C(C(=O)NS(=O)(=O)C2=CC=C(NC[C@H]3CC[C@](C)(O)CC3)C(=C2)[N+]([O-])=O)C(OC2=CN=C3NC=CC3=C2)=C1
References
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Recruiting Treatment Chronic Lymphocytic Leukemia 1 2 Not Yet Recruiting Treatment Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma 1 2 Recruiting Treatment Leukemias / Lymphoma / Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma / Relapsed Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma 1 2 Recruiting Treatment Recurrent Waldenstrom's Macroglobulinemia / Waldenstrom's Macroglobulinemia Refractory / Waldenström's Macroglobulinemia (WM) 1 1 Active Not Recruiting Treatment Mature B-cell Malignancies 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at May 17, 2024 17:39 / Updated at June 02, 2024 04:15