Cerebral Edema

Also known as: Edema of the cerebrum / Oedema cerebral / Cerebral oedema / Cerebral edema (disorder) / Edema cerebral / Oedema brain / Brain oedema / Brain swelling / Brain edema / Edema brain

DrugDrug NameDrug Description
DB00443BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
DB00297BupivacaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB09341Dextrose, unspecified formA form of glucose used for caloric supply and the replenishment of fluid in total parenteral nutrition and other therapies as well as for the treatment of hypoglycemic episodes.
DB09462GlycerinIt is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
DB14545Hydrocortisone succinateA corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
DB00742MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB14644Methylprednisolone hemisuccinateA water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DB00635PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DrugDrug NameTargetType
DB00443BetamethasoneGlucocorticoid receptortarget
DB00443BetamethasoneCytochrome P450 3A4enzyme
DB00443BetamethasoneATP-dependent translocase ABCB1transporter
DB00443BetamethasoneAromataseenzyme
DB00443BetamethasoneCytochrome P450 3A5enzyme
DB00443BetamethasoneCytochrome P450 3A7enzyme
DB00443BetamethasoneCytochrome P450 2A6enzyme
DB00443BetamethasoneCytochrome P450 1B1enzyme
DB00443BetamethasoneCytochrome P450 2B6enzyme
DB00443BetamethasoneCytochrome P450 2C8enzyme
DB00443BetamethasoneCytochrome P450 2C9enzyme
DB00443BetamethasoneCytochrome P450 2C19enzyme
DB00443BetamethasoneAlbumincarrier
DB00443BetamethasoneCorticosteroid-binding globulincarrier
DB00297BupivacaineSodium channel protein type 10 subunit alphatarget
DB00297BupivacaineProstaglandin E2 receptor EP1 subtypetarget
DB00297BupivacaineCytochrome P450 3A4enzyme
DB00297BupivacaineCytochrome P450 2C19enzyme
DB00297BupivacaineCytochrome P450 2D6enzyme
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneATP-dependent translocase ABCB1transporter
DB01234DexamethasoneATP-binding cassette sub-family C member 2transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB01234DexamethasoneAlbumincarrier
DB01234Dexamethasone11-beta-hydroxysteroid dehydrogenase type 2enzyme
DB01234Dexamethasone11-beta-hydroxysteroid dehydrogenase 1enzyme
DB01234DexamethasoneOrganic anion transporter 3transporter
DB09341Dextrose, unspecified formHexokinase-4enzyme
DB09341Dextrose, unspecified formHexokinase-1enzyme
DB09341Dextrose, unspecified formSolute carrier family 2, facilitated glucose transporter member 1transporter
DB09341Dextrose, unspecified formSolute carrier family 2, facilitated glucose transporter member 2transporter
DB09341Dextrose, unspecified formSolute carrier family 2, facilitated glucose transporter member 3transporter
DB09341Dextrose, unspecified formSolute carrier family 2, facilitated glucose transporter member 4transporter
DB09341Dextrose, unspecified formSolute carrier family 2, facilitated glucose transporter member 6transporter
DB09341Dextrose, unspecified formSolute carrier family 2, facilitated glucose transporter member 7transporter
DB09341Dextrose, unspecified formSolute carrier family 2, facilitated glucose transporter member 8transporter
DB09341Dextrose, unspecified formSolute carrier family 2, facilitated glucose transporter member 9transporter
DB09341Dextrose, unspecified formSolute carrier family 2, facilitated glucose transporter member 10transporter
DB09341Dextrose, unspecified formSolute carrier family 2, facilitated glucose transporter member 11transporter
DB09341Dextrose, unspecified formSolute carrier family 2, facilitated glucose transporter member 12transporter
DB09341Dextrose, unspecified formSodium/glucose cotransporter 1transporter
DB09462GlycerinGroup IIE secretory phospholipase A2target
DB09462GlycerinInositol-3-phosphate synthase 1target
DB09462GlycerinAll-trans-retinol dehydrogenase [NAD(+)] ADH1Btarget
DB09462GlycerinInositol 1,4,5-trisphosphate-gated calcium channel ITPR1target
DB09462GlycerinGlycodelintarget
DB09462GlycerinAlpha-N-acetylgalactosaminidasetarget
DB09462GlycerinADP-ribosylation factor 1target
DB09462GlycerinBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1target
DB09462GlycerinDNA mismatch repair protein MutLtarget
DB09462GlycerinRibonucleoside-diphosphate reductase 1 subunit betatarget
DB09462GlycerinAdenine DNA glycosylasetarget
DB09462GlycerintRNA (cytosine(38)-C(5))-methyltransferasetarget
DB09462GlycerinCytochrome P450 2E1enzyme
DB09462GlycerinAldehyde dehydrogenase 1A1enzyme
DB09462GlycerinPeroxisome proliferator-activated receptor deltatarget
DB09462GlycerinMaleylacetoacetate isomerasetarget
DB09462GlycerinAquaporin-7transporter
DB09462GlycerinAquaporin-9transporter
DB09462GlycerinGlycerol uptake facilitator proteintransporter
DB14545Hydrocortisone succinateCytochrome P450 3A4enzyme
DB14545Hydrocortisone succinateCytochrome P450 2C8enzyme
DB14545Hydrocortisone succinateCytochrome P450 11B1, mitochondrialenzyme
DB14545Hydrocortisone succinateCytochrome P450 11B2, mitochondrialenzyme
DB00742MannitolMannitol dehydrogenaseenzyme
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneATP-dependent translocase ABCB1transporter
DB00959MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
DB00959MethylprednisoloneCytochrome P450 2A6enzyme
DB00959MethylprednisoloneCytochrome P450 1B1enzyme
DB00959MethylprednisoloneCytochrome P450 2B6enzyme
DB00959MethylprednisoloneCytochrome P450 2C8enzyme
DB00959MethylprednisoloneCytochrome P450 2C9enzyme
DB00959MethylprednisoloneCytochrome P450 2C19enzyme
DB00959MethylprednisoloneAnnexin A1target
DB00959Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
DB00959Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
DB00959MethylprednisoloneAlbumincarrier
DB14644Methylprednisolone hemisuccinateCytochrome P450 3A4enzyme
DB14644Methylprednisolone hemisuccinateCytochrome P450 3A5enzyme
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneATP-dependent translocase ABCB1transporter
DB00860PrednisoloneAlbumincarrier
DB00635PrednisoneGlucocorticoid receptortarget
DB00635PrednisoneCytochrome P450 3A4enzyme
DB00635PrednisoneATP-dependent translocase ABCB1transporter
DB00635PrednisoneSolute carrier organic anion transporter family member 1A2transporter
DB00635PrednisoneCytochrome P450 2C19enzyme
DB00635PrednisoneAlbumincarrier
DB00635PrednisoneCytochrome P450 3A5enzyme
DB00635PrednisoneCorticosteroid-binding globulincarrier
DB00635PrednisoneCytochrome P450 3A Subfamilyenzyme
DB00635PrednisoneCytochrome P450 2A6enzyme
DB00635PrednisoneCytochrome P450 1B1enzyme
DB00635PrednisoneCytochrome P450 2B6enzyme
DB00635PrednisoneCytochrome P450 2C8enzyme
DB00635PrednisoneCytochrome P450 2C9enzyme
DB00635Prednisone11-beta-hydroxysteroid dehydrogenase 1enzyme
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneAlbumincarrier
DrugDrug NamePhaseStatusCount
DB00819AcetazolamideNot AvailableCompleted1
DB00742MannitolNot AvailableWithdrawn1
DB00820TadalafilNot AvailableCompleted1
DB08868Fingolimod0Completed1
DB01390Sodium bicarbonate0Withdrawn1
DB09153Sodium chloride0Withdrawn1
DB00872Conivaptan1Completed1
DB13906Aloe vera leaf1 / 2Withdrawn1
DB00126Ascorbic acid1 / 2Withdrawn1
DB01016Glyburide1 / 2Terminated1
DB09462Glycerin1 / 2Withdrawn1
DB00742Mannitol1 / 2Withdrawn1
DB02701Nicotinamide1 / 2Withdrawn1
DB00162Vitamin A1 / 2Withdrawn1
DB00819Acetazolamide2Completed1
DB00872Conivaptan2Withdrawn1
DB00514Dextromethorphan2Completed1
DB11994Diacerein2Withdrawn1
DB01075Diphenhydramine2Completed1
DB00927Famotidine2Completed1
DB14275Indian frankincense2Terminated1
DB16956L-Acetylleucine2Withdrawn1
DB00742Mannitol2Withdrawn1
DB00213Pantoprazole2Completed1
DB09153Sodium chloride2Withdrawn1
DB01234Dexamethasone3Unknown Status1