Reaction: monohydroxy-bendamustine (bendamustine metabolite HP1) to 1 product

Reaction
monohydroxy-bendamustine (bendamustine metabolite HP1)
DBMET01423
    dihydroxy-bendamustine (bendamustine metabolite HP2)
    DBMET01424
    Reaction type
    hydrolysis
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    inactive
    References
    1. Darwish M, Bond M, Hellriegel E, Robertson P Jr, Chovan JP: Pharmacokinetic and pharmacodynamic profile of bendamustine and its metabolites. Cancer Chemother Pharmacol. 2015 Jun;75(6):1143-54. doi: 10.1007/s00280-015-2727-6. Epub 2015 Apr 1. [Article]
    Comments
    Not Available
    Enzymes
    Not Available