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Clinical Trials & Rare Diseases
This package has 3 modules. The Clinical Trials Module has 15 tables. Preview the first five rows of each table or Explore the schema
Clinical Trials Module
15 Tables
Provides detailed information about clinical trials including interventions, trial arms, location, sponsor, trial conditions and more. Information is normalized, linked, and many relevant metadata descriptions are structured and ready for analysis.
id | trial_id | kind | label | description |
---|---|---|---|---|
000008b4-f6e0-4ff4-9483-3369f59f6a63 | NCT01232920 | active_comparator | Mycophenolate mofetil | |
00000ebb-1ffc-43df-a496-2da813782f88 | NCT06115408 | experimental | Drug;N-Acetylcysteine | 600 mg/day oral daily |
000016ed-4a6f-4cd8-add3-5a5e5eef7a82 | NCT01798745 | experimental | Cohort D: JNJ-54452840 for 5 days | Each patient will receive JNJ-54452840 once daily for 5 days at a dose determined by the Data Monitoring Committee (daily dose not exceeding 240 mg). |
000069a7-9ab3-427f-9735-00b0a4e2cfe8 | NCT05321706 | placebo_comparator | Placebo | Participants will be randomized in a 1:1 fashion to receive a matching tablet once daily for one year. |
00007875-d528-4445-b6b0-7601068667a7 | NCT05479812 | experimental | WTX-124 monotherapy dose expansion in advanced or metastatic RCC |
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id | trial_id | title | condition_id |
---|---|---|---|
0 | NCT00000726 | Acquired Immunodeficiency Syndrome | 48294 |
1 | NCT00000726 | Communicable Diseases | 28178 |
2 | NCT00000726 | HIV Infections | 35016 |
3 | NCT00000726 | Immunologic Deficiency Syndromes | 28099 |
4 | NCT00000726 | Cytomegalovirus Retinitis | 283 |
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id | trial_id | title | drug_id |
---|---|---|---|
0 | NCT00000726 | Foscarnet | 529 |
1 | NCT00000726 | Phosphonoacetic Acid | 2823 |
2 | NCT00000179 | Haloperidol decanoate | 502 |
3 | NCT00000179 | Trazodone | 656 |
4 | NCT00000179 | Haloperidol | 502 |
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trial_id | condition_id |
---|---|
NCT06207370 | 21 |
NCT01306058 | 46 |
NCT00513604 | 48 |
NCT00924001 | 48 |
NCT00301509 | 61 |
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trial_id | country |
---|---|
NCT00000102 | United States |
NCT00000105 | United States |
NCT00000116 | United States |
NCT00000117 | United States |
NCT00000119 | United States |
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id | trial_id | identifier | kind |
---|---|---|---|
0 | NCT00000726 | NCT00000726 | primary |
1 | NCT00000726 | ACTG 015 | org_study_id |
2 | NCT00000726 | FDA 20D | external |
3 | NCT00000726 | 10991 | external |
4 | NCT00001302 | NCT00001302 | primary |
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intervention_id | arm_group_id |
---|---|
34a3fa97-9477-44e9-a16b-e30536b50591 | 000008b4-f6e0-4ff4-9483-3369f59f6a63 |
d36bea2f-1715-4e95-a574-40c2094e8c92 | 00000ebb-1ffc-43df-a496-2da813782f88 |
3987507a-3a67-4775-a6cc-5dd682e00d0f | 000016ed-4a6f-4cd8-add3-5a5e5eef7a82 |
ec298768-6952-45b0-a7bb-f2ab7d7fd879 | 000069a7-9ab3-427f-9735-00b0a4e2cfe8 |
120d41fc-b3bb-4647-a248-f0e272c8d3b7 | 00007875-d528-4445-b6b0-7601068667a7 |
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id | trial_id | kind | title | description |
---|---|---|---|---|
0000418e-26ed-4068-8765-000622067c44 | NCT04982380 | drug | Siliankang simulating tablets | Patients will be instructed to continue current antidiabetic treatment, which should be kept unchanged throughout the trial, and start treatment with Siliankang simulative tablets 3 tablets p.o. tid for 12 weeks. |
00004645-6318-4239-86ca-127207ead9cb | NCT01097486 | procedure | Allograft | Single Dose Allograft Surgical Implantation |
00006a6b-958b-438f-be34-fae8b88fafda | NCT06338826 | drug | TDF - 245mg or TAF -25mg associated to 3TC - 300mg or FTC - 200mg and a NNRTI or PI/r or INSTI | The study will include patients under current daily antiretroviral tritherapy not modified for ≥ 12 months must including tenofovir disoproxil fumarate (TDF) 245mg or tenofovir alafenamide fumarate (TAF -25mg) associated to lamivudine (3TC - 300mg) or emtricitabine (FTC - 200mg) and a NNRTI or PI/r or INSTI to choose from
NNRTI = efavirenz, rilpivirine, etravirine, doravirine
PI/r = atazanavir/r ou darunavir/r
INSTI = bictegravir, dolutegravir, elvitegravir/cobicistat, raltegravir |
00007b19-8b85-422b-81cb-496b74cf195c | NCT04721054 | drug | Thoracic epidural effect on heart rate in Laparoscopic Cholecystectomy (bupivacaine and lignocaine) | patients in epidural anesthesia were given epidural anesthesia and assessed for heart rate and mean arterial pressure |
000097c5-d490-44ce-bc7e-eb473e8ccd78 | NCT04417907 | drug | Perampanel 4mg | Healthy adults will take 4mg perampanel PO QD for six weeks |
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id | intervention_id | drug_id |
---|---|---|
0 | 8f38e770-d936-4484-9823-47910c3ec57f | 529 |
1 | cbdc0507-bfda-4f1d-b0cb-ec29a3b3eed8 | 11951 |
2 | f3a5cb19-e734-4dc6-8a68-3906fb6725e7 | 656 |
3 | 887b7097-5b00-4138-9734-2a0c9ecd083e | 502 |
4 | 7c8c40e6-872d-4dee-81e2-c48cad4e7a59 | 245 |
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id | intervention_id | name |
---|---|---|
0 | 72bf20ce-9e35-452a-9fb0-5278e331ffc4 | elavil plus prozac |
1 | a09d3d37-3a38-4798-bade-ac1c9d4383eb | Elavil |
2 | 88525cb1-9c27-4be5-a4c4-0057fecbb8c8 | Subutex |
3 | 88525cb1-9c27-4be5-a4c4-0057fecbb8c8 | Suboxone |
4 | f354cce2-1963-4e14-95d9-a3c8aa29ff15 | Revia |
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id | intervention_id | product_id |
---|---|---|
0 | 8f38e770-d936-4484-9823-47910c3ec57f | 413284 |
1 | f3a5cb19-e734-4dc6-8a68-3906fb6725e7 | 94335 |
2 | 887b7097-5b00-4138-9734-2a0c9ecd083e | 464755 |
3 | 1c9dd64d-84fd-41af-833e-01b664d9aa1c | 469533 |
4 | 86894763-b424-4483-9135-d50dbc18b2fb | 465274 |
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trial_id | phase |
---|---|
NCT00017381 | 0 |
NCT00091286 | 0 |
NCT00140556 | 0 |
NCT00176059 | 0 |
NCT00187941 | 0 |
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id | trial_id | title | agency_class | lead_sponsor |
---|---|---|---|---|
0 | NCT00000726 | National Institute of Allergy and Infectious Diseases (NIAID) | nih | 1 |
1 | NCT00001302 | National Cancer Institute (NCI) | nih | 1 |
2 | NCT00000179 | National Institute on Aging (NIA) | nih | 1 |
3 | NCT00000333 | National Institute on Drug Abuse (NIDA) | nih | 1 |
4 | NCT00000333 | Washington D.C. Veterans Affairs Medical Center | us_fed | 0 |
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identifier | title | official_title | status | purpose | expanded_access | why_stopped | why_stopped_category_id | start_date | end_date | end_date_kind |
---|---|---|---|---|---|---|---|---|---|---|
NCT00000102 | Congenital Adrenal Hyperplasia: Calcium Channels as Therapeutic Targets | completed | treatment | 1 | ||||||
NCT00000105 | Vaccination With Tetanus and KLH to Assess Immune Responses. | Vaccination With Tetanus Toxoid and Keyhole Limpet Hemocyanin (KLH) to Assess Antigen-Specific Immune Responses | terminated | 1 | Replaced by another study. | 2002-07-01 | 2012-03-01 | actual | ||
NCT00000114 | Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa | completed | treatment | 1 | 1984-05-01 | 1987-06-01 | actual | |||
NCT00000115 | Randomized Trial of Acetazolamide for Uveitis-Associated Cystoid Macular Edema | completed | treatment | 1 | 1990-12-01 | 1994-06-01 | actual | |||
NCT00000116 | Randomized Trial of DHA for Retinitis Pigmentosa Patients Receiving Vitamin A | Clinical Trial of Docosahexaenoic Acid (DHA) in Patients With Retinitis Pigmentosa Receiving Vitamin A Treatment | completed | treatment | 1 | 1996-05-01 | 2002-09-01 | actual |
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id | category | definition | safety_efficacy_concern |
---|---|---|---|
1 | Business Decision | The trial has been terminated due to strategic decisions, administrative reasons, sponsor, or company decision. | 0 |
6 | Change in Medical/Clinical Practices | The drug(s) of interest might not be suitable to the disease that they were trying to treat due to changes in medical or clinical practices.
1. Surgeons stopped doing procedures
2. Additional published information on the topic since starting the study
3. Study no longer consistent with current clinical practice
| 0 |
11 | Competing Studies | The study drug(s) are having worse/futile results in similar competing trials. | 0 |
16 | Completed | Trial was successfully completed (user input was incorrectly marked as terminated). [eg. accrual was reached] | 0 |
21 | Conflict of Interest | The parties involved had conflicts of interests. | 0 |
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Showing 15 of 15 tables
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