Crystallization and preliminary X-ray analysis of the thymidylate kinase from Mycobacterium tuberculosis.
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Li de la Sierra I, Munier-Lehmann H, Gilles AM, Barzu O, Delarue M
Crystallization and preliminary X-ray analysis of the thymidylate kinase from Mycobacterium tuberculosis.
Acta Crystallogr D Biol Crystallogr. 2000 Feb;56(Pt 2):226-8.
- PubMed ID
- 10666613 [ View in PubMed]
- Abstract
Mycobacterium tuberculosis thymidylate kinase complexed with the substrate deoxythymidine monophosphate was crystallized in the hexagonal space group P6(5)22 or P6(1)22, with unit-cell parameters a = b = 76.62, c = 134.38 A and one single monomer of 23 kDa in the asymmetric unit. Cryo-cooled crystals diffract at 1.94 A resolution using synchrotron radiation.