Crystallization and preliminary X-ray analysis of the thymidylate kinase from Mycobacterium tuberculosis.

Article Details

Citation

Li de la Sierra I, Munier-Lehmann H, Gilles AM, Barzu O, Delarue M

Crystallization and preliminary X-ray analysis of the thymidylate kinase from Mycobacterium tuberculosis.

Acta Crystallogr D Biol Crystallogr. 2000 Feb;56(Pt 2):226-8.

PubMed ID
10666613 [ View in PubMed
]
Abstract

Mycobacterium tuberculosis thymidylate kinase complexed with the substrate deoxythymidine monophosphate was crystallized in the hexagonal space group P6(5)22 or P6(1)22, with unit-cell parameters a = b = 76.62, c = 134.38 A and one single monomer of 23 kDa in the asymmetric unit. Cryo-cooled crystals diffract at 1.94 A resolution using synchrotron radiation.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Thymidylate kinaseP9WKE1Details