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Displaying targets 1 - 25 of 6103 in total
TargetOrganismDescription# of Drugs
(2Z,6E)-farnesyl diphosphate synthaseMycobacterium tuberculosisCatalyzes the condensation of only one isopentenyl pyrophosphate (IPP) unit in the cis configuration to E-geranyl dip...  more2Details
(3R)-3-hydroxyacyl-CoA dehydrogenaseHumansRequired for the solubility and assembly of the heterotetramer 3-ketoacyl-[acyl carrier protein] (ACP) reductase func...  more2Details
(5R)-carbapenem-3-carboxylate synthasePectobacterium carotovorum subsp. carotovorumCatalyzes the Fe(2+) and alpha-ketoglutarate-dependent conversion of (3S,5S)-carbapenam to (5R)-carbapenem, an essent...  more1Details
(S)-2-haloacid dehalogenasePseudomonas sp. (strain YL)Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalk...  more2Details
(S)-2-haloacid dehalogenaseXanthobacter autotrophicusCatalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalk...  more2Details
(S)-mandelate dehydrogenasePseudomonas putidaCatalyzes the dehydrogenation of (S)-mandelate to phenylglyoxylate (benzoylformate). Is likely involved in the utiliz...  more5Details
1,2-dihydroxynaphthalene dioxygenasePseudomonas sp. (strain C18)Involved in the naphthalene catabolic pathway. Catalyzes the meta-cleavage of 1,2-dihydroxynaphthalene (1,2-DHN) to y...  more3Details
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialHumansA cytochrome P450 monooxygenase with a key role in vitamin D catabolism and calcium homeostasis. Via C24- and C23-oxi...  more8Details
1,3-beta-glucan synthase component FKS1Aspergillus niger (strain CBS 513.88 / FGSC A1513)Catalytic subunit of the 1,3-beta-glucan synthase. Synthesizes 1,3-beta-glucan, a major structural component of the f...  more4Details
1,3-beta-glucan synthase component GSC2Baker's yeastAlternate catalytic subunit of the 1,3-beta-glucan synthase (GS) complex. Synthesizes 1,3-beta-glucan, a major struct...  more6Details
1,4-alpha-glucan-branching enzymeHumansGlycogen-branching enzyme participates in the glycogen biosynthetic process along with glycogenin and glycogen syntha...  more1Details
1,4-Dihydroxy-2-naphthoyl-CoA synthaseMycobacterium tuberculosisConverts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).2Details
1-acyl-sn-glycerol-3-phosphate acyltransferase betaHumansConverts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosp...  more1Details
1-aminocyclopropane-1-carboxylate deaminasePseudomonas sp. (strain ACP)Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC...  more6Details
1-aminocyclopropane-1-carboxylate synthase-like protein 1HumansDoes not catalyze the synthesis of 1-aminocyclopropane-1-carboxylate but is capable of catalyzing the deamination of ...  more1Details
1-deoxy-D-xylulose 5-phosphate reductoisomeraseEscherichia coli (strain K12)Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-ery...  more3Details
1-deoxypentalenic acid 11-beta-hydroxylaseStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)Catalyzes the conversion of 1-deoxypentalenic acid to 11-beta-hydroxy-1-deoxypentalenic acid in the biosynthesis of n...  more1Details
1-phosphatidylinositol 3-phosphate 5-kinaseHumansDual specificity kinase implicated in myriad essential cellular processes such as maintenance of endomembrane homeost...  more1Details
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1HumansThe production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is media...  more2Details
1-phosphatidylinositol phosphodiesteraseListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Important fac...  more1Details
1-phosphatidylinositol phosphodiesteraseBacillus cereusCleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates.2Details
10 kDa heat shock protein, mitochondrialHumansCo-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitate...  more1Details
11-beta-hydroxysteroid dehydrogenase 1HumansControls the reversible conversion of biologically active glucocorticoids such as cortisone to cortisol, and 11-dehyd...  more39Details
11-beta-hydroxysteroid dehydrogenase type 2HumansCatalyzes the conversion of biologically active 11beta-hydroxyglucocorticoids (11beta-hydroxysteroid) such as cortiso...  more19Details
11beta-hydroxysteroid dehydrogenaseHumans and other mammalsNot Available2Details
Displaying targets 1 - 25 of 6103 in total