Drugs, their targets and the nature and number of drug targets.

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Imming P, Sinning C, Meyer A

Drugs, their targets and the nature and number of drug targets.

Nat Rev Drug Discov. 2006 Oct;5(10):821-34.

PubMed ID

17016423 [ View in PubMed

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Abstract

What is a drug target? And how many such targets are there? Here, we consider the nature of drug targets, and by classifying known drug substances on the basis of the discussed principles we provide an estimation of the total number of current drug targets.