Benzamides and cholinesterases.

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Vacca C, Maione S, Tozzi A, Marmo E

Benzamides and cholinesterases.

Res Commun Chem Pathol Pharmacol. 1987 Feb;55(2):193-201.

PubMed ID

3823608 [ View in PubMed

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Abstract

At certain doses metoclopramide (MT), sulpiride and bromopride produce anti-cholinesterase effects as shown by studies on the serum and erythrocyte cholinesterases of the rabbit and the dog, and by those on the hypotensive effect of ACh incubated with rabbit serum in the presence or absence of MT. The anti-cholinesterase effect of MT was more intensive than that of sulpiride, bromopride, procainamide or procaine, but less pronounced than that of prostigmine.

DrugBank Data that Cites this Article

Drug Enzymes

Drug	Enzyme	Kind	Organism	Pharmacological Action	Actions
Sulpiride	Cholinesterase	Protein	Humans	Unknown	Inhibitor	Details