Thiazide Diuretics

Article Details

Citation

Copy to clipboard

Akbari P, Khorasani-Zadeh A

Thiazide Diuretics

.

PubMed ID

30422513 [ View in PubMed

]

Abstract

Thiazide diuretics are an FDA-approved class of drugs that inhibit reabsorption of 3% to 5% of luminal sodium in the distal convoluted tubule of the nephron. By doing so, thiazide diuretics promote natriuresis and diuresis. Three thiazide diuretics are commonly used: hydrochlorothiazide (HCTZ), chlorthalidone, and indapamide.

DrugBank Data that Cites this Article

Drugs

Indapamide

Hydrochlorothiazide

Drug Transporters

Drug	Transporter	Kind	Organism	Pharmacological Action	Actions
Hydrochlorothiazide	Solute carrier family 22 member 11	Protein	Humans	Unknown	Substrate	Details
Hydrochlorothiazide	Solute carrier family 22 member 6	Protein	Humans	Unknown	Substrate Inhibitor	Details