Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing.
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Limonciel A, Moenks K, Stanzel S, Truisi GL, Parmentier C, Aschauer L, Wilmes A, Richert L, Hewitt P, Mueller SO, Lukas A, Kopp-Schneider A, Leonard MO, Jennings P
Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing.
Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):7-18. doi: 10.1016/j.tiv.2014.12.011. Epub 2015 Jan 13.
- PubMed ID
- 25596134 [ View in PubMed]
- Abstract
High content omic methods provide a deep insight into cellular events occurring upon chemical exposure of a cell population or tissue. However, this improvement in analytic precision is not yet matched by a thorough understanding of molecular mechanisms that would allow an optimal interpretation of these biological changes. For transcriptomics (TCX), one type of molecular effects that can be assessed already is the modulation of the transcriptional activity of a transcription factor (TF). As more ChIP-seq datasets reporting genes specifically bound by a TF become publicly available for mining, the generation of target gene lists of TFs of toxicological relevance becomes possible, based on actual protein-DNA interaction and modulation of gene expression. In this study, we generated target gene signatures for Nrf2, ATF4, XBP1, p53, HIF1a, AhR and PPAR gamma and tracked TF modulation in a large collection of in vitro TCX datasets from renal and hepatic cell models exposed to clinical nephro- and hepato-toxins. The result is a global monitoring of TF modulation with great promise as a mechanistically based tool for chemical hazard identification.
DrugBank Data that Cites this Article
- Pharmaco-transcriptomics
Drug Drug Groups Gene Gene ID Change Interaction Chromosome Acetaminophen Approved BCAR3 8412 downregulated Acetaminophen results in decreased expression of BCAR3 mRNA 1p22.1 Acetaminophen Approved BNIP3 664 upregulated Acetaminophen results in increased expression of BNIP3 mRNA 10q26.3 Acetaminophen Approved HIST1H1C 3006 upregulated Acetaminophen results in increased expression of HIST1H1C mRNA 6p22.2 Acetaminophen Approved NIN 51199 upregulated Acetaminophen results in increased expression of NIN mRNA 14q22.1 Acetaminophen Approved RND3 390 downregulated Acetaminophen results in decreased expression of RND3 mRNA 2q23.3 Acetaminophen Approved SLC1A7 6512 downregulated Acetaminophen results in decreased expression of SLC1A7 mRNA 1p32.3 Acetaminophen Approved SORL1 6653 downregulated Acetaminophen results in decreased expression of SORL1 mRNA 11q24.1 Acetaminophen Approved VEGFB 7423 downregulated Acetaminophen results in decreased expression of VEGFB mRNA 11q13.1 Acetaminophen Approved YARS 8565 downregulated Acetaminophen results in decreased expression of YARS mRNA 1p35.1 Adefovir dipivoxil Approved Investigational AK4 205 upregulated adefovir dipivoxil results in increased expression of AK4 mRNA 1p31.3 Adefovir dipivoxil Approved Investigational AKR1C2 1646 downregulated adefovir dipivoxil results in decreased expression of AKR1C2 mRNA 10p15.1 Adefovir dipivoxil Approved Investigational ALDH18A1 5832 downregulated adefovir dipivoxil results in decreased expression of ALDH18A1 mRNA 10q24.1 Adefovir dipivoxil Approved Investigational ALDH1A3 220 upregulated adefovir dipivoxil results in increased expression of ALDH1A3 mRNA 15q26.3 Adefovir dipivoxil Approved Investigational ALS2CL 259173 upregulated adefovir dipivoxil results in increased expression of ALS2CL mRNA 3p21.31 Adefovir dipivoxil Approved Investigational ANGPTL4 51129 upregulated adefovir dipivoxil results in increased expression of ANGPTL4 mRNA 19p13.2 Adefovir dipivoxil Approved Investigational ASNS 440 downregulated adefovir dipivoxil results in decreased expression of ASNS mRNA 7q21.3 Adefovir dipivoxil Approved Investigational ATAD2 29028 upregulated adefovir dipivoxil results in increased expression of ATAD2 mRNA 8q24.13 Adefovir dipivoxil Approved Investigational ATF3 467 upregulated adefovir dipivoxil results in increased expression of ATF3 mRNA 1q32.3 Adefovir dipivoxil Approved Investigational AURKB 9212 upregulated adefovir dipivoxil results in increased expression of AURKB mRNA 17p13.1 Adefovir dipivoxil Approved Investigational AXL 558 upregulated adefovir dipivoxil results in increased expression of AXL mRNA 19q13.2 Adefovir dipivoxil Approved Investigational BAX 581 upregulated adefovir dipivoxil results in increased expression of BAX mRNA 19q13.33 Adefovir dipivoxil Approved Investigational BCAR3 8412 upregulated adefovir dipivoxil results in increased expression of BCAR3 mRNA 1p22.1 Adefovir dipivoxil Approved Investigational BEND5 79656 downregulated adefovir dipivoxil results in decreased expression of BEND5 mRNA 1p33 Adefovir dipivoxil Approved Investigational BMF 90427 downregulated adefovir dipivoxil results in decreased expression of BMF mRNA 15q15.1 Adefovir dipivoxil Approved Investigational BTG2 7832 upregulated adefovir dipivoxil results in increased expression of BTG2 mRNA 1q32.1 Adefovir dipivoxil Approved Investigational CCNE2 9134 upregulated adefovir dipivoxil results in increased expression of CCNE2 mRNA 8q22.1 Adefovir dipivoxil Approved Investigational CDK6 1021 upregulated adefovir dipivoxil results in increased expression of CDK6 mRNA 7q21.2 Adefovir dipivoxil Approved Investigational CDKN1A 1026 upregulated adefovir dipivoxil results in increased expression of CDKN1A mRNA 6p21.2 Adefovir dipivoxil Approved Investigational CMBL 134147 upregulated adefovir dipivoxil results in increased expression of CMBL mRNA 5p15.2 Adefovir dipivoxil Approved Investigational COCH 1690 upregulated adefovir dipivoxil results in increased expression of COCH mRNA 14q12 Adefovir dipivoxil Approved Investigational COL4A1 1282 downregulated adefovir dipivoxil results in decreased expression of COL4A1 mRNA 13q34 Adefovir dipivoxil Approved Investigational CTH 1491 downregulated adefovir dipivoxil results in decreased expression of CTH mRNA 1p31.1 Adefovir dipivoxil Approved Investigational CTSC 1075 downregulated adefovir dipivoxil results in decreased expression of CTSC mRNA 11q14.2 Adefovir dipivoxil Approved Investigational CYP1B1 1545 upregulated adefovir dipivoxil results in increased expression of CYP1B1 mRNA 2p22.2 Adefovir dipivoxil Approved Investigational DDB2 1643 upregulated adefovir dipivoxil results in increased expression of DDB2 mRNA 11p11.2 Adefovir dipivoxil Approved Investigational DGKA 1606 upregulated adefovir dipivoxil results in increased expression of DGKA mRNA 12q13.2 Adefovir dipivoxil Approved Investigational DLGAP5 9787 upregulated adefovir dipivoxil results in increased expression of DLGAP5 mRNA 14q22.3 Adefovir dipivoxil Approved Investigational DLX1 1745 downregulated adefovir dipivoxil results in decreased expression of DLX1 mRNA 2q31.1 Adefovir dipivoxil Approved Investigational DPYSL3 1809 upregulated adefovir dipivoxil results in increased expression of DPYSL3 mRNA 5q32 Adefovir dipivoxil Approved Investigational EFNA1 1942 downregulated adefovir dipivoxil results in decreased expression of EFNA1 mRNA 1q22 Adefovir dipivoxil Approved Investigational FAS 355 upregulated adefovir dipivoxil results in increased expression of FAS mRNA 10q23.31 Adefovir dipivoxil Approved Investigational FBXO22 26263 upregulated adefovir dipivoxil results in increased expression of FBXO22 mRNA 15q24.2 Adefovir dipivoxil Approved Investigational GABARAPL1 23710 downregulated adefovir dipivoxil results in decreased expression of GABARAPL1 mRNA 12p13.2 Adefovir dipivoxil Approved Investigational GADD45A 1647 upregulated adefovir dipivoxil results in increased expression of GADD45A mRNA 1p31.3 Adefovir dipivoxil Approved Investigational GALNT16 57452 downregulated adefovir dipivoxil results in decreased expression of GALNT16 mRNA 14q24.1 Adefovir dipivoxil Approved Investigational GCNT3 9245 upregulated adefovir dipivoxil results in increased expression of GCNT3 mRNA 15q22.2 Adefovir dipivoxil Approved Investigational GDF15 9518 upregulated adefovir dipivoxil results in increased expression of GDF15 mRNA 19p13.11 Adefovir dipivoxil Approved Investigational GOT1 2805 downregulated adefovir dipivoxil results in decreased expression of GOT1 mRNA 10q24.2 Adefovir dipivoxil Approved Investigational GPR87 53836 upregulated adefovir dipivoxil results in increased expression of GPR87 mRNA 3q25.1 Adefovir dipivoxil Approved Investigational HIST1H1C 3006 upregulated adefovir dipivoxil results in increased expression of HIST1H1C mRNA 6p22.2 Adefovir dipivoxil Approved Investigational HMOX1 3162 downregulated adefovir dipivoxil results in decreased expression of HMOX1 mRNA 22q12.3 Adefovir dipivoxil Approved Investigational HSPA1B 3304 downregulated adefovir dipivoxil results in decreased expression of HSPA1B mRNA 6p21.33 Adefovir dipivoxil Approved Investigational KAT6B 23522 downregulated adefovir dipivoxil results in decreased expression of KAT6B mRNA 10q22.2 Adefovir dipivoxil Approved Investigational KDM3A 55818 downregulated adefovir dipivoxil results in decreased expression of KDM3A mRNA 2p11.2 Adefovir dipivoxil Approved Investigational KRT15 3866 upregulated adefovir dipivoxil results in increased expression of KRT15 mRNA 17q21.2 Adefovir dipivoxil Approved Investigational LAMA3 3909 upregulated adefovir dipivoxil results in increased expression of LAMA3 mRNA 18q11.2 Adefovir dipivoxil Approved Investigational MAP3K8 1326 upregulated adefovir dipivoxil results in increased expression of MAP3K8 mRNA 10p11.23 Adefovir dipivoxil Approved Investigational MDM2 4193 upregulated adefovir dipivoxil results in increased expression of MDM2 mRNA 12q15 Adefovir dipivoxil Approved Investigational MXI1 4601 downregulated adefovir dipivoxil results in decreased expression of MXI1 mRNA 10q25.2 Adefovir dipivoxil Approved Investigational NCAPD2 9918 upregulated adefovir dipivoxil results in increased expression of NCAPD2 mRNA 12p13.31 Adefovir dipivoxil Approved Investigational NINJ1 4814 upregulated adefovir dipivoxil results in increased expression of NINJ1 mRNA 9q22.31 Adefovir dipivoxil Approved Investigational NQO1 1728 downregulated adefovir dipivoxil results in decreased expression of NQO1 mRNA 16q22.1 Adefovir dipivoxil Approved Investigational NREP 9315 downregulated adefovir dipivoxil results in decreased expression of NREP mRNA 5q22.1 Adefovir dipivoxil Approved Investigational NTPCR 84284 upregulated adefovir dipivoxil results in increased expression of NTPCR mRNA 1q42.2 Adefovir dipivoxil Approved Investigational P4HA1 5033 downregulated adefovir dipivoxil results in decreased expression of P4HA1 mRNA 10q22.1 Adefovir dipivoxil Approved Investigational PANK1 53354 downregulated adefovir dipivoxil results in decreased expression of PANK1 mRNA 10q23.31 Adefovir dipivoxil Approved Investigational PDIA5 10954 upregulated adefovir dipivoxil results in increased expression of PDIA5 mRNA 3q21.1 Adefovir dipivoxil Approved Investigational PDLIM1 9124 upregulated adefovir dipivoxil results in increased expression of PDLIM1 mRNA 10q23.33 Adefovir dipivoxil Approved Investigational PHLDA3 23612 upregulated adefovir dipivoxil results in increased expression of PHLDA3 mRNA 1q32.1 Adefovir dipivoxil Approved Investigational PIDD1 55367 upregulated adefovir dipivoxil results in increased expression of PIDD1 mRNA 11p15.5 Adefovir dipivoxil Approved Investigational PIR 8544 upregulated adefovir dipivoxil results in increased expression of PIR mRNA Xp22.2 Adefovir dipivoxil Approved Investigational PLEC 5339 upregulated adefovir dipivoxil results in increased expression of PLEC mRNA 8q24.3 Adefovir dipivoxil Approved Investigational PMAIP1 5366 upregulated adefovir dipivoxil results in increased expression of PMAIP1 mRNA 18q21.32 Adefovir dipivoxil Approved Investigational PPM1D 8493 upregulated adefovir dipivoxil results in increased expression of PPM1D mRNA 17q23.3 Adefovir dipivoxil Approved Investigational PRC1 9055 upregulated adefovir dipivoxil results in increased expression of PRC1 mRNA 15q26.1 Adefovir dipivoxil Approved Investigational PRDM1 639 upregulated adefovir dipivoxil results in increased expression of PRDM1 mRNA 6q21 Adefovir dipivoxil Approved Investigational PRKAB2 5565 downregulated adefovir dipivoxil results in decreased expression of PRKAB2 mRNA 1q21.1 Adefovir dipivoxil Approved Investigational PSAT1 29968 downregulated adefovir dipivoxil results in decreased expression of PSAT1 mRNA 9q21.2 Adefovir dipivoxil Approved Investigational RARA 5914 downregulated adefovir dipivoxil results in decreased expression of RARA mRNA 17q21.2 Adefovir dipivoxil Approved Investigational RPS27L 51065 upregulated adefovir dipivoxil results in increased expression of RPS27L mRNA 15q22.2 Adefovir dipivoxil Approved Investigational RRM2B 50484 upregulated adefovir dipivoxil results in increased expression of RRM2B mRNA 8q22.3 Adefovir dipivoxil Approved Investigational SERPINB5 5268 upregulated adefovir dipivoxil results in increased expression of SERPINB5 mRNA 18q21.33 Adefovir dipivoxil Approved Investigational SESN1 27244 upregulated adefovir dipivoxil results in increased expression of SESN1 mRNA 6q21 Adefovir dipivoxil Approved Investigational SFN 2810 upregulated adefovir dipivoxil results in increased expression of SFN mRNA 1p36.11 Adefovir dipivoxil Approved Investigational SH3TC1 54436 downregulated adefovir dipivoxil results in decreased expression of SH3TC1 mRNA 4p16.1 Adefovir dipivoxil Approved Investigational SLC27A2 11001 downregulated adefovir dipivoxil results in decreased expression of SLC27A2 mRNA 15q21.2 Adefovir dipivoxil Approved Investigational SLC6A9 6536 downregulated adefovir dipivoxil results in decreased expression of SLC6A9 mRNA 1p34.1 Adefovir dipivoxil Approved Investigational SLCO2B1 11309 upregulated adefovir dipivoxil results in increased expression of SLCO2B1 mRNA 11q13 Adefovir dipivoxil Approved Investigational SMAP1 60682 downregulated adefovir dipivoxil results in decreased expression of SMAP1 mRNA 6q13 Adefovir dipivoxil Approved Investigational SULF2 55959 upregulated adefovir dipivoxil results in increased expression of SULF2 mRNA 20q13.12 Adefovir dipivoxil Approved Investigational TIGAR 57103 upregulated adefovir dipivoxil results in increased expression of TIGAR mRNA 12p13.32 Adefovir dipivoxil Approved Investigational TIPARP 25976 upregulated adefovir dipivoxil results in increased expression of TIPARP mRNA 3q25.31 Adefovir dipivoxil Approved Investigational TNFRSF10B 8795 upregulated adefovir dipivoxil results in increased expression of TNFRSF10B mRNA 8p21.3 Adefovir dipivoxil Approved Investigational TNFSF9 8744 upregulated adefovir dipivoxil results in increased expression of TNFSF9 mRNA 19p13.3 Adefovir dipivoxil Approved Investigational TP53INP1 94241 upregulated adefovir dipivoxil results in increased expression of TP53INP1 mRNA 8q22.1 Adefovir dipivoxil Approved Investigational TRAFD1 10906 downregulated adefovir dipivoxil results in decreased expression of TRAFD1 mRNA 12q24.13 Adefovir dipivoxil Approved Investigational TRIAP1 51499 upregulated adefovir dipivoxil results in increased expression of TRIAP1 mRNA 12q24.31 Adefovir dipivoxil Approved Investigational UBE2O 63893 downregulated adefovir dipivoxil results in decreased expression of UBE2O mRNA 17q25.1 Adefovir dipivoxil Approved Investigational WDR63 126820 upregulated adefovir dipivoxil results in increased expression of WDR63 mRNA 1p22.3 Adefovir dipivoxil Approved Investigational YARS 8565 downregulated adefovir dipivoxil results in decreased expression of YARS mRNA 1p35.1 Adefovir dipivoxil Approved Investigational ZMAT3 64393 upregulated adefovir dipivoxil results in increased expression of ZMAT3 mRNA 3q26.32 Cidofovir Approved AARS 16 downregulated cidofovir results in decreased expression of AARS mRNA 16q22.1 Cidofovir Approved ABCB6 10058 upregulated cidofovir results in increased expression of ABCB6 mRNA 2q35 Cidofovir Approved ABCB9 23457 upregulated cidofovir results in increased expression of ABCB9 mRNA 12q24.31 Cidofovir Approved ABCG1 9619 downregulated cidofovir results in decreased expression of ABCG1 mRNA 21q22.3 Cidofovir Approved ABHD4 63874 upregulated cidofovir results in increased expression of ABHD4 mRNA 14q11.2 Cidofovir Approved ACSL1 2180 downregulated cidofovir results in decreased expression of ACSL1 mRNA 4q35.1 Cidofovir Approved AGRN 375790 upregulated cidofovir results in increased expression of AGRN mRNA 1p36.33 Cidofovir Approved AK3 50808 upregulated cidofovir results in increased expression of AK3 mRNA 9p24.1 Cidofovir Approved AK4 205 upregulated cidofovir results in increased expression of AK4 mRNA 1p31.3 Cidofovir Approved ALDH1A3 220 upregulated cidofovir results in increased expression of ALDH1A3 mRNA 15q26.3 Cidofovir Approved ALDOA 226 upregulated cidofovir results in increased expression of ALDOA mRNA 16p11.2 Cidofovir Approved ANGPTL4 51129 upregulated cidofovir results in increased expression of ANGPTL4 mRNA 19p13.2 Cidofovir Approved ANKRA2 57763 downregulated cidofovir results in decreased expression of ANKRA2 mRNA 5q13.2 Cidofovir Approved ARHGEF10 9639 downregulated cidofovir results in decreased expression of ARHGEF10 mRNA 8p23.3 Cidofovir Approved ASNS 440 upregulated cidofovir results in increased expression of ASNS mRNA 7q21.3 Cidofovir Approved ATAD2 29028 upregulated cidofovir results in increased expression of ATAD2 mRNA 8q24.13 Cidofovir Approved ATF3 467 upregulated cidofovir results in increased expression of ATF3 mRNA 1q32.3 Cidofovir Approved ATXN1 6310 downregulated cidofovir results in decreased expression of ATXN1 mRNA 6p22.3 Cidofovir Approved AURKB 9212 upregulated cidofovir results in increased expression of AURKB mRNA 17p13.1 Cidofovir Approved AXL 558 upregulated cidofovir results in increased expression of AXL mRNA 19q13.2 Cidofovir Approved BAX 581 upregulated cidofovir results in increased expression of BAX mRNA 19q13.33 Cidofovir Approved BBC3 27113 upregulated cidofovir results in increased expression of BBC3 mRNA 19q13.32 Cidofovir Approved BCAT2 587 upregulated cidofovir results in increased expression of BCAT2 mRNA 19q13.33 Cidofovir Approved BMF 90427 upregulated cidofovir results in increased expression of BMF mRNA 15q15.1 Cidofovir Approved BRD2 6046 downregulated cidofovir results in decreased expression of BRD2 mRNA 6p21.32 Cidofovir Approved BTG2 7832 upregulated cidofovir results in increased expression of BTG2 mRNA 1q32.1 Cidofovir Approved CAMKK2 10645 upregulated cidofovir results in increased expression of CAMKK2 mRNA 12q24.31 Cidofovir Approved CARS 833 downregulated cidofovir results in decreased expression of CARS mRNA 11p15.4 Cidofovir Approved CCDC90B 60492 downregulated cidofovir results in decreased expression of CCDC90B mRNA 11q14.1 Cidofovir Approved CCNE2 9134 upregulated cidofovir results in increased expression of CCNE2 mRNA 8q22.1 Cidofovir Approved CCNG2 901 downregulated cidofovir results in decreased expression of CCNG2 mRNA 4q21.1 Cidofovir Approved CDKN1A 1026 upregulated cidofovir results in increased expression of CDKN1A mRNA 6p21.2 Cidofovir Approved CERS5 91012 upregulated cidofovir results in increased expression of CERS5 mRNA 12q13.12 Cidofovir Approved CLIP4 79745 downregulated cidofovir results in decreased expression of CLIP4 mRNA 2p23.2 Cidofovir Approved CMBL 134147 upregulated cidofovir results in increased expression of CMBL mRNA 5p15.2 Cidofovir Approved COCH 1690 upregulated cidofovir results in increased expression of COCH mRNA 14q12 Cidofovir Approved CP 1356 upregulated cidofovir results in increased expression of CP mRNA 3q24-q25.1 Cidofovir Approved CTDP1 9150 downregulated cidofovir results in decreased expression of CTDP1 mRNA 18q23 Cidofovir Approved CTSC 1075 upregulated cidofovir results in increased expression of CTSC mRNA 11q14.2 Cidofovir Approved CTTN 2017 upregulated cidofovir results in increased expression of CTTN mRNA 11q13.3 Cidofovir Approved CYP1A1 1543 downregulated cidofovir results in decreased expression of CYP1A1 mRNA 15q24.1 Cidofovir Approved CYP1B1 1545 upregulated cidofovir results in increased expression of CYP1B1 mRNA 2p22.2 Cidofovir Approved DDB2 1643 upregulated cidofovir results in increased expression of DDB2 mRNA 11p11.2 Cidofovir Approved DDIT3 1649 downregulated cidofovir results in decreased expression of DDIT3 mRNA 12q13.3 Cidofovir Approved DDX17 10521 downregulated cidofovir results in decreased expression of DDX17 mRNA 22q13.1 Cidofovir Approved DGKA 1606 upregulated cidofovir results in increased expression of DGKA mRNA 12q13.2 Cidofovir Approved DHX37 57647 downregulated cidofovir results in decreased expression of DHX37 mRNA 12q24.31 Cidofovir Approved DLGAP5 9787 upregulated cidofovir results in increased expression of DLGAP5 mRNA 14q22.3 Cidofovir Approved DNAJB9 4189 upregulated cidofovir results in increased expression of DNAJB9 mRNA 7q31.1 Cidofovir Approved DPM3 54344 upregulated cidofovir results in increased expression of DPM3 mRNA 1q22 Cidofovir Approved DPYSL3 1809 upregulated cidofovir results in increased expression of DPYSL3 mRNA 5q32 Cidofovir Approved DUSP22 56940 upregulated cidofovir results in increased expression of DUSP22 mRNA 6p25.3 Cidofovir Approved DUSP5 1847 upregulated cidofovir results in increased expression of DUSP5 mRNA 10q25.2 Cidofovir Approved EBLN2 55096 downregulated cidofovir results in decreased expression of EBLN2 mRNA 3p13 Cidofovir Approved EFNA1 1942 downregulated cidofovir results in decreased expression of EFNA1 mRNA 1q22 Cidofovir Approved EIF3C 8663 downregulated cidofovir results in decreased expression of EIF3C mRNA 16p11.2 Cidofovir Approved ELK4 2005 downregulated cidofovir results in decreased expression of ELK4 mRNA 1q32.1 Cidofovir Approved ENO2 2026 upregulated cidofovir results in increased expression of ENO2 mRNA 12p13.31 Cidofovir Approved ENOSF1 55556 downregulated cidofovir results in decreased expression of ENOSF1 mRNA 18p11.32 Cidofovir Approved ENTPD7 57089 upregulated cidofovir results in increased expression of ENTPD7 mRNA 10q24.2 Cidofovir Approved EP400 57634 downregulated cidofovir results in decreased expression of EP400 mRNA 12q24.33 Cidofovir Approved EPRS 2058 downregulated cidofovir results in decreased expression of EPRS mRNA 1q41 Cidofovir Approved FAM162A 26355 downregulated cidofovir results in decreased expression of FAM162A mRNA 3q21.1 Cidofovir Approved FAM210A 125228 upregulated cidofovir results in increased expression of FAM210A mRNA 18p11.21 Cidofovir Approved FAM210B 116151 upregulated cidofovir results in increased expression of FAM210B mRNA 20q13.2 Cidofovir Approved FAM212B 55924 upregulated cidofovir results in increased expression of FAM212B mRNA 1p13.2 Cidofovir Approved FAM214A 56204 downregulated cidofovir results in decreased expression of FAM214A mRNA 15q21.2-q21.3 Cidofovir Approved FAM84B 157638 upregulated cidofovir results in increased expression of FAM84B mRNA 8q24.21 Cidofovir Approved FAM89A 375061 upregulated cidofovir results in increased expression of FAM89A mRNA 1q42.2 Cidofovir Approved FBXO22 26263 upregulated cidofovir results in increased expression of FBXO22 mRNA 15q24.2 Cidofovir Approved FBXO30 84085 downregulated cidofovir results in decreased expression of FBXO30 mRNA 6q24.3 Cidofovir Approved FECH 2235 downregulated cidofovir results in decreased expression of FECH mRNA 18q21.31 Cidofovir Approved FOSL1 8061 upregulated cidofovir results in increased expression of FOSL1 mRNA 11q13.1 Cidofovir Approved FOSL2 2355 downregulated cidofovir results in decreased expression of FOSL2 mRNA 2p23.2 Cidofovir Approved FREM2 341640 downregulated cidofovir results in decreased expression of FREM2 mRNA 13q13.3 Cidofovir Approved GABARAPL1 23710 downregulated cidofovir results in decreased expression of GABARAPL1 mRNA 12p13.2 Cidofovir Approved GARS 2617 upregulated cidofovir results in increased expression of GARS mRNA 7p14.3 Cidofovir Approved GBE1 2632 upregulated cidofovir results in increased expression of GBE1 mRNA 3p12.2 Cidofovir Approved GCLC 2729 downregulated cidofovir results in decreased expression of GCLC mRNA 6p12.1 Cidofovir Approved GCLM 2730 upregulated cidofovir results in increased expression of GCLM mRNA 1p22.1 Cidofovir Approved GCNT3 9245 upregulated cidofovir results in increased expression of GCNT3 mRNA 15q22.2 Cidofovir Approved GDF15 9518 upregulated cidofovir results in increased expression of GDF15 mRNA 19p13.11 Cidofovir Approved GOLIM4 27333 downregulated cidofovir results in decreased expression of GOLIM4 mRNA 3q26.2 Cidofovir Approved GOT1 2805 upregulated cidofovir results in increased expression of GOT1 mRNA 10q24.2 Cidofovir Approved GPA33 10223 upregulated cidofovir results in increased expression of GPA33 mRNA 1q24.1 Cidofovir Approved GPAT3 84803 upregulated cidofovir results in increased expression of GPAT3 mRNA 4q21.23 Cidofovir Approved GPNMB 10457 downregulated cidofovir results in decreased expression of GPNMB mRNA 7p15.3 Cidofovir Approved GPR87 53836 downregulated cidofovir results in decreased expression of GPR87 mRNA 3q25.1 Cidofovir Approved GSR 2936 upregulated cidofovir results in increased expression of GSR mRNA 8p12 Cidofovir Approved HERC3 8916 downregulated cidofovir results in decreased expression of HERC3 mRNA 4q22.1 Cidofovir Approved HIST1H1C 3006 upregulated cidofovir results in increased expression of HIST1H1C mRNA 6p22.2 Cidofovir Approved HMOX1 3162 upregulated cidofovir results in increased expression of HMOX1 mRNA 22q12.3 Cidofovir Approved HSPA1B 3304 downregulated cidofovir results in decreased expression of HSPA1B mRNA 6p21.33 Cidofovir Approved HSPA5 3309 downregulated cidofovir results in decreased expression of HSPA5 mRNA 9q33.3 Cidofovir Approved IARS 3376 upregulated cidofovir results in increased expression of IARS mRNA 9q22.31 Cidofovir Approved IDS 3423 downregulated cidofovir results in decreased expression of IDS mRNA Xq28 Cidofovir Approved INSIG1 3638 upregulated cidofovir results in increased expression of INSIG1 mRNA 7q36.3 Cidofovir Approved ISCU 23479 upregulated cidofovir results in increased expression of ISCU mRNA 12q23.3 Cidofovir Approved KAT6B 23522 downregulated cidofovir results in decreased expression of KAT6B mRNA 10q22.2 Cidofovir Approved KDM3A 55818 downregulated cidofovir results in decreased expression of KDM3A mRNA 2p11.2 Cidofovir Approved KEAP1 9817 upregulated cidofovir results in increased expression of KEAP1 mRNA 19p13.2 Cidofovir Approved KRT15 3866 upregulated cidofovir results in increased expression of KRT15 mRNA 17q21.2 Cidofovir Approved KRT19 3880 upregulated cidofovir results in increased expression of KRT19 mRNA 17q21.2 Cidofovir Approved LARS 51520 downregulated cidofovir results in decreased expression of LARS mRNA 5q32 Cidofovir Approved LMCD1 29995 upregulated cidofovir results in increased expression of LMCD1 mRNA 3p25.3 Cidofovir Approved LTN1 26046 downregulated cidofovir results in decreased expression of LTN1 mRNA 21q21.3 Cidofovir Approved MAN1A2 10905 downregulated cidofovir results in decreased expression of MAN1A2 mRNA 1p12 Cidofovir Approved MAPRE2 10982 upregulated cidofovir results in increased expression of MAPRE2 mRNA 18q12.1-q12.2 Cidofovir Approved MT2A 4502 upregulated cidofovir results in increased expression of MT2A mRNA 16q13 Cidofovir Approved MTDH 92140 downregulated cidofovir results in decreased expression of MTDH mRNA 8q22.1 Cidofovir Approved MTFP1 51537 upregulated cidofovir results in increased expression of MTFP1 mRNA 22q12.2 Cidofovir Approved MXI1 4601 downregulated cidofovir results in decreased expression of MXI1 mRNA 10q25.2 Cidofovir Approved NAMPT 10135 upregulated cidofovir results in increased expression of NAMPT mRNA 7q22.3 Cidofovir Approved NARS 4677 downregulated cidofovir results in decreased expression of NARS mRNA 18q21.31 Cidofovir Approved NEDD9 4739 downregulated cidofovir results in decreased expression of NEDD9 mRNA 6p24.2 Cidofovir Approved NIN 51199 downregulated cidofovir results in decreased expression of NIN mRNA 14q22.1 Cidofovir Approved NINJ1 4814 upregulated cidofovir results in increased expression of NINJ1 mRNA 9q22.31 Cidofovir Approved NQO1 1728 downregulated cidofovir results in decreased expression of NQO1 mRNA 16q22.1 Cidofovir Approved NR3C1 2908 downregulated cidofovir results in decreased expression of NR3C1 mRNA 5q31.3 Cidofovir Approved NREP 9315 upregulated cidofovir results in increased expression of NREP mRNA 5q22.1 Cidofovir Approved NTPCR 84284 upregulated cidofovir results in increased expression of NTPCR mRNA 1q42.2 Cidofovir Approved OXSM 54995 upregulated cidofovir results in increased expression of OXSM mRNA 3p24.2 Cidofovir Approved P4HA1 5033 downregulated cidofovir results in decreased expression of P4HA1 mRNA 10q22.1 Cidofovir Approved PANK1 53354 downregulated cidofovir results in decreased expression of PANK1 mRNA 10q23.31 Cidofovir Approved PDE8A 5151 downregulated cidofovir results in decreased expression of PDE8A mRNA 15q25.3 Cidofovir Approved PDIA5 10954 upregulated cidofovir results in increased expression of PDIA5 mRNA 3q21.1 Cidofovir Approved PDK4 5166 upregulated cidofovir results in increased expression of PDK4 mRNA 7q21.3 Cidofovir Approved PDLIM1 9124 upregulated cidofovir results in increased expression of PDLIM1 mRNA 10q23.33 Cidofovir Approved PHLDA3 23612 upregulated cidofovir results in increased expression of PHLDA3 mRNA 1q32.1 Cidofovir Approved PIR 8544 upregulated cidofovir results in increased expression of PIR mRNA Xp22.2 Cidofovir Approved PLEC 5339 downregulated cidofovir results in decreased expression of PLEC mRNA 8q24.3 Cidofovir Approved PLK3 1263 upregulated cidofovir results in increased expression of PLK3 mRNA 1p34.1 Cidofovir Approved PMEPA1 56937 upregulated cidofovir results in increased expression of PMEPA1 mRNA 20q13.31 Cidofovir Approved PNPLA6 10908 upregulated cidofovir results in increased expression of PNPLA6 mRNA 19p13.2 Cidofovir Approved PODXL 5420 downregulated cidofovir results in decreased expression of PODXL mRNA 7q32.3 Cidofovir Approved POLR3F 10621 downregulated cidofovir results in decreased expression of POLR3F mRNA 20p11.23 Cidofovir Approved PPAN-P2RY11 692312 downregulated cidofovir results in decreased expression of PPAN-P2RY11 mRNA 19p13.2 Cidofovir Approved PPFIBP1 8496 upregulated cidofovir results in increased expression of PPFIBP1 mRNA 12p11.23, 12p11.22 Cidofovir Approved PPIG 9360 downregulated cidofovir results in decreased expression of PPIG mRNA 2q31.1 Cidofovir Approved PPP1R15A 23645 upregulated cidofovir results in increased expression of PPP1R15A mRNA 19q13.2 Cidofovir Approved PPP4R2 151987 downregulated cidofovir results in decreased expression of PPP4R2 mRNA 3p13 Cidofovir Approved PRC1 9055 upregulated cidofovir results in increased expression of PRC1 mRNA 15q26.1 Cidofovir Approved PRDM1 639 downregulated cidofovir results in decreased expression of PRDM1 mRNA 6q21 Cidofovir Approved PRKAB2 5565 downregulated cidofovir results in decreased expression of PRKAB2 mRNA 1q21.1 Cidofovir Approved PRPS1 5631 upregulated cidofovir results in increased expression of PRPS1 mRNA Xq22.3 Cidofovir Approved PSAT1 29968 upregulated cidofovir results in increased expression of PSAT1 mRNA 9q21.2 Cidofovir Approved PSPC1 55269 downregulated cidofovir results in decreased expression of PSPC1 mRNA 13q12.11 Cidofovir Approved PYCR1 5831 upregulated cidofovir results in increased expression of PYCR1 mRNA 17q25.3 Cidofovir Approved RAB26 25837 upregulated cidofovir results in increased expression of RAB26 mRNA 16p13.3 Cidofovir Approved RAB31 11031 upregulated cidofovir results in increased expression of RAB31 mRNA 18p11.22 Cidofovir Approved RARA 5914 upregulated cidofovir results in increased expression of RARA mRNA 17q21.2 Cidofovir Approved RFFL 117584 upregulated cidofovir results in increased expression of RFFL mRNA 17q12 Cidofovir Approved RIT1 6016 upregulated cidofovir results in increased expression of RIT1 mRNA 1q22 Cidofovir Approved RLF 6018 downregulated cidofovir results in decreased expression of RLF mRNA 1p34.2 Cidofovir Approved RND1 27289 upregulated cidofovir results in increased expression of RND1 mRNA 12q13.12 Cidofovir Approved RNF121 55298 downregulated cidofovir results in decreased expression of RNF121 mRNA 11q13.4 Cidofovir Approved RPS27L 51065 upregulated cidofovir results in increased expression of RPS27L mRNA 15q22.2 Cidofovir Approved RRM2B 50484 downregulated cidofovir results in decreased expression of RRM2B mRNA 8q22.3 Cidofovir Approved RSRC2 65117 downregulated cidofovir results in decreased expression of RSRC2 mRNA 12q24.31 Cidofovir Approved RUNX1 861 upregulated cidofovir results in increased expression of RUNX1 mRNA 21q22.12 Cidofovir Approved RUNX2 860 upregulated cidofovir results in increased expression of RUNX2 mRNA 6p21.1 Cidofovir Approved SARS 6301 upregulated cidofovir results in increased expression of SARS mRNA 1p13.3 Cidofovir Approved SDF2L1 23753 upregulated cidofovir results in increased expression of SDF2L1 mRNA 22q11.21 Cidofovir Approved SERPINB5 5268 upregulated cidofovir results in increased expression of SERPINB5 mRNA 18q21.33 Cidofovir Approved SERTAD1 29950 upregulated cidofovir results in increased expression of SERTAD1 mRNA 19q13.1-q13.2 Cidofovir Approved SESN1 27244 upregulated cidofovir results in increased expression of SESN1 mRNA 6q21 Cidofovir Approved SETX 23064 downregulated cidofovir results in decreased expression of SETX mRNA 9q34.13 Cidofovir Approved SFN 2810 upregulated cidofovir results in increased expression of SFN mRNA 1p36.11 Cidofovir Approved SH3TC1 54436 downregulated cidofovir results in decreased expression of SH3TC1 mRNA 4p16.1 Cidofovir Approved SIPA1L2 57568 downregulated cidofovir results in decreased expression of SIPA1L2 mRNA 1q42.2 Cidofovir Approved SIVA1 10572 upregulated cidofovir results in increased expression of SIVA1 mRNA 14q32.33 Cidofovir Approved SLC1A4 6509 upregulated cidofovir results in increased expression of SLC1A4 mRNA 2p14 Cidofovir Approved SLC1A5 6510 upregulated cidofovir results in increased expression of SLC1A5 mRNA 19q13.32 Cidofovir Approved SLC25A20 788 upregulated cidofovir results in increased expression of SLC25A20 mRNA 3p21.31 Cidofovir Approved SLC27A2 11001 downregulated cidofovir results in decreased expression of SLC27A2 mRNA 15q21.2 Cidofovir Approved SLC2A1 6513 upregulated cidofovir results in increased expression of SLC2A1 mRNA 1p34.2 Cidofovir Approved SLC3A2 6520 upregulated cidofovir results in increased expression of SLC3A2 mRNA 11q12.3 Cidofovir Approved SLC6A9 6536 downregulated cidofovir results in decreased expression of SLC6A9 mRNA 1p34.1 Cidofovir Approved SLC7A1 6541 upregulated cidofovir results in increased expression of SLC7A1 mRNA 13q12.3 Cidofovir Approved SLC7A5 8140 upregulated cidofovir results in increased expression of SLC7A5 mRNA 16q24.2 Cidofovir Approved SLCO2B1 11309 upregulated cidofovir results in increased expression of SLCO2B1 mRNA 11q13 Cidofovir Approved SMAP1 60682 downregulated cidofovir results in decreased expression of SMAP1 mRNA 6q13 Cidofovir Approved SON 6651 downregulated cidofovir results in decreased expression of SON mRNA 21q22.11 Cidofovir Approved SORL1 6653 downregulated cidofovir results in decreased expression of SORL1 mRNA 11q24.1 Cidofovir Approved SRD5A3 79644 downregulated cidofovir results in decreased expression of SRD5A3 mRNA 4q12 Cidofovir Approved SRXN1 140809 upregulated cidofovir results in increased expression of SRXN1 mRNA 20p13 Cidofovir Approved STRBP 55342 downregulated cidofovir results in decreased expression of STRBP mRNA 9q33.1-q33.3 Cidofovir Approved SULF2 55959 downregulated cidofovir results in decreased expression of SULF2 mRNA 20q13.12 Cidofovir Approved TALDO1 6888 upregulated cidofovir results in increased expression of TALDO1 mRNA 11p15.5 Cidofovir Approved TAOK1 57551 downregulated cidofovir results in decreased expression of TAOK1 mRNA 17q11.2 Cidofovir Approved TARS 6897 downregulated cidofovir results in decreased expression of TARS mRNA 5p13.3 Cidofovir Approved TBXAS1 6916 upregulated cidofovir results in increased expression of TBXAS1 mRNA 7q34 Cidofovir Approved TFAP2A 7020 downregulated cidofovir results in decreased expression of TFAP2A mRNA 6p24.3 Cidofovir Approved TIGAR 57103 upregulated cidofovir results in increased expression of TIGAR mRNA 12p13.32 Cidofovir Approved TINAG 27283 downregulated cidofovir results in decreased expression of TINAG mRNA 6p12.1 Cidofovir Approved TIPARP 25976 upregulated cidofovir results in increased expression of TIPARP mRNA 3q25.31 Cidofovir Approved TMEM45B 120224 downregulated cidofovir results in decreased expression of TMEM45B mRNA 11q24.3 Cidofovir Approved TMEM94 9772 downregulated cidofovir results in decreased expression of TMEM94 mRNA 17q25.1 Cidofovir Approved TMTC2 160335 downregulated cidofovir results in decreased expression of TMTC2 mRNA 12q21.31 Cidofovir Approved TNFSF9 8744 upregulated cidofovir results in increased expression of TNFSF9 mRNA 19p13.3 Cidofovir Approved TP53I3 9540 upregulated cidofovir results in increased expression of TP53I3 mRNA 2p23.3 Cidofovir Approved TP53TG1 11257 upregulated cidofovir results in increased expression of TP53TG1 mRNA 7q21.12 Cidofovir Approved TPCN1 53373 upregulated cidofovir results in increased expression of TPCN1 mRNA 12q24.13 Cidofovir Approved TRAFD1 10906 upregulated cidofovir results in increased expression of TRAFD1 mRNA 12q24.13 Cidofovir Approved TRIAP1 51499 upregulated cidofovir results in increased expression of TRIAP1 mRNA 12q24.31 Cidofovir Approved TROVE2 6738 downregulated cidofovir results in decreased expression of TROVE2 mRNA 1q31.2 Cidofovir Approved TSPAN12 23554 downregulated cidofovir results in decreased expression of TSPAN12 mRNA 7q31.31 Cidofovir Approved TXN 7295 upregulated cidofovir results in increased expression of TXN mRNA 9q31.3 Cidofovir Approved TXNRD1 7296 upregulated cidofovir results in increased expression of TXNRD1 mRNA 12q23.3 Cidofovir Approved UBE2G2 7327 upregulated cidofovir results in increased expression of UBE2G2 mRNA 21q22.3 Cidofovir Approved VEGFB 7423 upregulated cidofovir results in increased expression of VEGFB mRNA 11q13.1 Cidofovir Approved VIPR1 7433 upregulated cidofovir results in increased expression of VIPR1 mRNA 3p22.1 Cidofovir Approved VTCN1 79679 upregulated cidofovir results in increased expression of VTCN1 mRNA 1p13.1-p12 Cidofovir Approved WARS 7453 upregulated cidofovir results in increased expression of WARS mRNA 14q32.2 Cidofovir Approved WWC2 80014 downregulated cidofovir results in decreased expression of WWC2 mRNA 4q35.1 Cidofovir Approved XBP1 7494 upregulated cidofovir results in increased expression of XBP1 mRNA 22q12.1 Cidofovir Approved XPC 7508 upregulated cidofovir results in increased expression of XPC mRNA 3p25.1 Cidofovir Approved YTHDC2 64848 downregulated cidofovir results in decreased expression of YTHDC2 mRNA 5q22.2 Cidofovir Approved ZMAT3 64393 upregulated cidofovir results in increased expression of ZMAT3 mRNA 3q26.32 Cidofovir Approved ZNF561 93134 downregulated cidofovir results in decreased expression of ZNF561 mRNA 19p13.2 Cyclosporine Approved Investigational Vet Approved AARS 16 upregulated Cyclosporine results in increased expression of AARS mRNA 16q22.1 Cyclosporine Approved Investigational Vet Approved ABCB6 10058 upregulated Cyclosporine results in increased expression of ABCB6 mRNA 2q35 Cyclosporine Approved Investigational Vet Approved ABCC3 8714 downregulated Cyclosporine results in decreased expression of ABCC3 mRNA 17q21.33 Cyclosporine Approved Investigational Vet Approved ABCG1 9619 upregulated Cyclosporine results in increased expression of ABCG1 mRNA 21q22.3 Cyclosporine Approved Investigational Vet Approved ABHD4 63874 upregulated Cyclosporine results in increased expression of ABHD4 mRNA 14q11.2 Cyclosporine Approved Investigational Vet Approved ADCY1 107 downregulated Cyclosporine results in decreased expression of ADCY1 mRNA 7p12.3 Cyclosporine Approved Investigational Vet Approved AGRN 375790 downregulated Cyclosporine results in decreased expression of AGRN mRNA 1p36.33 Cyclosporine Approved Investigational Vet Approved AIFM2 84883 upregulated Cyclosporine results in increased expression of AIFM2 mRNA 10q22.1 Cyclosporine Approved Investigational Vet Approved AK3 50808 downregulated Cyclosporine results in decreased expression of AK3 mRNA 9p24.1 Cyclosporine Approved Investigational Vet Approved AKR1C2 1646 upregulated Cyclosporine results in increased expression of AKR1C2 mRNA 10p15.1 Cyclosporine Approved Investigational Vet Approved ALDH18A1 5832 downregulated Cyclosporine results in decreased expression of ALDH18A1 mRNA 10q24.1 Cyclosporine Approved Investigational Vet Approved ALDOA 226 upregulated Cyclosporine results in increased expression of ALDOA mRNA 16p11.2 Cyclosporine Approved Investigational Vet Approved ALS2CL 259173 upregulated Cyclosporine results in increased expression of ALS2CL mRNA 3p21.31 Cyclosporine Approved Investigational Vet Approved ANKRA2 57763 upregulated Cyclosporine results in increased expression of ANKRA2 mRNA 5q13.2 Cyclosporine Approved Investigational Vet Approved ARFGEF2 10564 upregulated Cyclosporine results in increased expression of ARFGEF2 mRNA 20q13.13 Cyclosporine Approved Investigational Vet Approved ARHGEF10 9639 downregulated Cyclosporine results in decreased expression of ARHGEF10 mRNA 8p23.3 Cyclosporine Approved Investigational Vet Approved ARL1 400 upregulated Cyclosporine results in increased expression of ARL1 mRNA 12q23.2 Cyclosporine Approved Investigational Vet Approved ASNS 440 upregulated Cyclosporine results in increased expression of ASNS mRNA 7q21.3 Cyclosporine Approved Investigational Vet Approved ATF3 467 upregulated Cyclosporine results in increased expression of ATF3 mRNA 1q32.3 Cyclosporine Approved Investigational Vet Approved AURKB 9212 downregulated Cyclosporine results in decreased expression of AURKB mRNA 17p13.1 Cyclosporine Approved Investigational Vet Approved AXL 558 downregulated Cyclosporine results in decreased expression of AXL mRNA 19q13.2 Cyclosporine Approved Investigational Vet Approved BAX 581 upregulated Cyclosporine results in increased expression of BAX mRNA 19q13.33 Cyclosporine Approved Investigational Vet Approved BCAR3 8412 upregulated Cyclosporine results in increased expression of BCAR3 mRNA 1p22.1 Cyclosporine Approved Investigational Vet Approved BCAT1 586 upregulated Cyclosporine results in increased expression of BCAT1 mRNA 12p12.1 Cyclosporine Approved Investigational Vet Approved BCAT2 587 downregulated Cyclosporine results in decreased expression of BCAT2 mRNA 19q13.33 Cyclosporine Approved Investigational Vet Approved BCL3 602 downregulated Cyclosporine results in decreased expression of BCL3 mRNA 19q13.32 Cyclosporine Approved Investigational Vet Approved BEND5 79656 downregulated Cyclosporine results in decreased expression of BEND5 mRNA 1p33 Cyclosporine Approved Investigational Vet Approved BEND6 221336 upregulated Cyclosporine results in increased expression of BEND6 mRNA 6p12.1 Cyclosporine Approved Investigational Vet Approved BHLHE40 8553 upregulated Cyclosporine results in increased expression of BHLHE40 mRNA 3p26.1 Cyclosporine Approved Investigational Vet Approved BMF 90427 downregulated Cyclosporine results in decreased expression of BMF mRNA 15q15.1 Cyclosporine Approved Investigational Vet Approved BNIP3 664 upregulated Cyclosporine results in increased expression of BNIP3 mRNA 10q26.3 Cyclosporine Approved Investigational Vet Approved BRD2 6046 upregulated Cyclosporine results in increased expression of BRD2 mRNA 6p21.32 Cyclosporine Approved Investigational Vet Approved BTG2 7832 downregulated Cyclosporine results in decreased expression of BTG2 mRNA 1q32.1 Cyclosporine Approved Investigational Vet Approved CARS 833 upregulated Cyclosporine results in increased expression of CARS mRNA 11p15.4 Cyclosporine Approved Investigational Vet Approved CCNG2 901 downregulated Cyclosporine results in decreased expression of CCNG2 mRNA 4q21.1 Cyclosporine Approved Investigational Vet Approved CDK6 1021 downregulated Cyclosporine results in decreased expression of CDK6 mRNA 7q21.2 Cyclosporine Approved Investigational Vet Approved CDKN1A 1026 upregulated Cyclosporine results in increased expression of CDKN1A mRNA 6p21.2 Cyclosporine Approved Investigational Vet Approved CHSY1 22856 downregulated Cyclosporine results in decreased expression of CHSY1 mRNA 15q26.3 Cyclosporine Approved Investigational Vet Approved CLIP4 79745 upregulated Cyclosporine results in increased expression of CLIP4 mRNA 2p23.2 Cyclosporine Approved Investigational Vet Approved COL24A1 255631 upregulated Cyclosporine results in increased expression of COL24A1 mRNA 1p22.3 Cyclosporine Approved Investigational Vet Approved COL4A1 1282 downregulated Cyclosporine results in decreased expression of COL4A1 mRNA 13q34 Cyclosporine Approved Investigational Vet Approved CTH 1491 upregulated Cyclosporine results in increased expression of CTH mRNA 1p31.1 Cyclosporine Approved Investigational Vet Approved CTSC 1075 downregulated Cyclosporine results in decreased expression of CTSC mRNA 11q14.2 Cyclosporine Approved Investigational Vet Approved CYP1A1 1543 downregulated Cyclosporine results in decreased expression of CYP1A1 mRNA 15q24.1 Cyclosporine Approved Investigational Vet Approved CYP1B1 1545 downregulated Cyclosporine results in decreased expression of CYP1B1 mRNA 2p22.2 Cyclosporine Approved Investigational Vet Approved DDIT3 1649 upregulated Cyclosporine results in increased expression of DDIT3 mRNA 12q13.3 Cyclosporine Approved Investigational Vet Approved DDIT4 54541 upregulated Cyclosporine results in increased expression of DDIT4 mRNA 10q22.1 Cyclosporine Approved Investigational Vet Approved DDX24 57062 upregulated Cyclosporine results in increased expression of DDX24 mRNA 14q32.12 Cyclosporine Approved Investigational Vet Approved DGKA 1606 downregulated Cyclosporine results in decreased expression of DGKA mRNA 12q13.2 Cyclosporine Approved Investigational Vet Approved DHX37 57647 upregulated Cyclosporine results in increased expression of DHX37 mRNA 12q24.31 Cyclosporine Approved Investigational Vet Approved DLGAP5 9787 downregulated Cyclosporine results in decreased expression of DLGAP5 mRNA 14q22.3 Cyclosporine Approved Investigational Vet Approved DNAJB2 3300 upregulated Cyclosporine results in increased expression of DNAJB2 mRNA 2q35 Cyclosporine Approved Investigational Vet Approved DNAJB9 4189 upregulated Cyclosporine results in increased expression of DNAJB9 mRNA 7q31.1 Cyclosporine Approved Investigational Vet Approved DPM3 54344 downregulated Cyclosporine results in decreased expression of DPM3 mRNA 1q22 Cyclosporine Approved Investigational Vet Approved DPP9 91039 upregulated Cyclosporine results in increased expression of DPP9 mRNA 19p13.3 Cyclosporine Approved Investigational Vet Approved DUSP5 1847 upregulated Cyclosporine results in increased expression of DUSP5 mRNA 10q25.2 Cyclosporine Approved Investigational Vet Approved EDC3 80153 downregulated Cyclosporine results in decreased expression of EDC3 mRNA 15q24.1 Cyclosporine Approved Investigational Vet Approved EFNA1 1942 downregulated Cyclosporine results in decreased expression of EFNA1 mRNA 1q22 Cyclosporine Approved Investigational Vet Approved EIF1 10209 upregulated Cyclosporine results in increased expression of EIF1 mRNA 17q21.2 Cyclosporine Approved Investigational Vet Approved ELF4 2000 upregulated Cyclosporine results in increased expression of ELF4 mRNA Xq26.1 Cyclosporine Approved Investigational Vet Approved ENO2 2026 upregulated Cyclosporine results in increased expression of ENO2 mRNA 12p13.31 Cyclosporine Approved Investigational Vet Approved ENOSF1 55556 downregulated Cyclosporine results in decreased expression of ENOSF1 mRNA 18p11.32 Cyclosporine Approved Investigational Vet Approved ENTPD7 57089 upregulated Cyclosporine results in increased expression of ENTPD7 mRNA 10q24.2 Cyclosporine Approved Investigational Vet Approved EPRS 2058 upregulated Cyclosporine results in increased expression of EPRS mRNA 1q41 Cyclosporine Approved Investigational Vet Approved EXOC7 23265 upregulated Cyclosporine results in increased expression of EXOC7 mRNA 17q25.1 Cyclosporine Approved Investigational Vet Approved FAM162A 26355 downregulated Cyclosporine results in decreased expression of FAM162A mRNA 3q21.1 Cyclosporine Approved Investigational Vet Approved FAM210A 125228 upregulated Cyclosporine results in increased expression of FAM210A mRNA 18p11.21 Cyclosporine Approved Investigational Vet Approved FAM210B 116151 downregulated Cyclosporine results in decreased expression of FAM210B mRNA 20q13.2 Cyclosporine Approved Investigational Vet Approved FAM214A 56204 upregulated Cyclosporine results in increased expression of FAM214A mRNA 15q21.2-q21.3 Cyclosporine Approved Investigational Vet Approved FAM84B 157638 downregulated Cyclosporine results in decreased expression of FAM84B mRNA 8q24.21 Cyclosporine Approved Investigational Vet Approved FAM89A 375061 upregulated Cyclosporine results in increased expression of FAM89A mRNA 1q42.2 Cyclosporine Approved Investigational Vet Approved FAS 355 upregulated Cyclosporine results in increased expression of FAS mRNA 10q23.31 Cyclosporine Approved Investigational Vet Approved FBXO22 26263 upregulated Cyclosporine results in increased expression of FBXO22 mRNA 15q24.2 Cyclosporine Approved Investigational Vet Approved FBXO30 84085 upregulated Cyclosporine results in increased expression of FBXO30 mRNA 6q24.3 Cyclosporine Approved Investigational Vet Approved FLVCR2 55640 downregulated Cyclosporine results in decreased expression of FLVCR2 mRNA 14q24.3 Cyclosporine Approved Investigational Vet Approved FOSL1 8061 upregulated Cyclosporine results in increased expression of FOSL1 mRNA 11q13.1 Cyclosporine Approved Investigational Vet Approved FTH1 2495 upregulated Cyclosporine results in increased expression of FTH1 mRNA 11q12.3 Cyclosporine Approved Investigational Vet Approved GABARAPL1 23710 upregulated Cyclosporine results in increased expression of GABARAPL1 mRNA 12p13.2 Cyclosporine Approved Investigational Vet Approved GADD45A 1647 upregulated Cyclosporine results in increased expression of GADD45A mRNA 1p31.3 Cyclosporine Approved Investigational Vet Approved GALNT16 57452 downregulated Cyclosporine results in decreased expression of GALNT16 mRNA 14q24.1 Cyclosporine Approved Investigational Vet Approved GARS 2617 upregulated Cyclosporine results in increased expression of GARS mRNA 7p14.3 Cyclosporine Approved Investigational Vet Approved GBE1 2632 upregulated Cyclosporine results in increased expression of GBE1 mRNA 3p12.2 Cyclosporine Approved Investigational Vet Approved GCLC 2729 upregulated Cyclosporine results in increased expression of GCLC mRNA 6p12.1 Cyclosporine Approved Investigational Vet Approved GCLM 2730 upregulated Cyclosporine results in increased expression of GCLM mRNA 1p22.1 Cyclosporine Approved Investigational Vet Approved GCNT3 9245 upregulated Cyclosporine results in increased expression of GCNT3 mRNA 15q22.2 Cyclosporine Approved Investigational Vet Approved GDF15 9518 upregulated Cyclosporine results in increased expression of GDF15 mRNA 19p13.11 Cyclosporine Approved Investigational Vet Approved GOLIM4 27333 downregulated Cyclosporine results in decreased expression of GOLIM4 mRNA 3q26.2 Cyclosporine Approved Investigational Vet Approved GORASP1 64689 downregulated Cyclosporine results in decreased expression of GORASP1 mRNA 3p22.2 Cyclosporine Approved Investigational Vet Approved GOT1 2805 downregulated Cyclosporine results in decreased expression of GOT1 mRNA 10q24.2 Cyclosporine Approved Investigational Vet Approved GPAT3 84803 upregulated Cyclosporine results in increased expression of GPAT3 mRNA 4q21.23 Cyclosporine Approved Investigational Vet Approved GPNMB 10457 downregulated Cyclosporine results in decreased expression of GPNMB mRNA 7p15.3 Cyclosporine Approved Investigational Vet Approved HIST1H1C 3006 upregulated Cyclosporine results in increased expression of HIST1H1C mRNA 6p22.2 Cyclosporine Approved Investigational Vet Approved HMOX1 3162 upregulated Cyclosporine results in increased expression of HMOX1 mRNA 22q12.3 Cyclosporine Approved Investigational Vet Approved HSPA1B 3304 upregulated Cyclosporine results in increased expression of HSPA1B mRNA 6p21.33 Cyclosporine Approved Investigational Vet Approved HSPA5 3309 upregulated Cyclosporine results in increased expression of HSPA5 mRNA 9q33.3 Cyclosporine Approved Investigational Vet Approved HTATIP2 10553 upregulated Cyclosporine results in increased expression of HTATIP2 mRNA 11p15.1 Cyclosporine Approved Investigational Vet Approved IARS 3376 upregulated Cyclosporine results in increased expression of IARS mRNA 9q22.31 Cyclosporine Approved Investigational Vet Approved IGF2R 3482 upregulated Cyclosporine results in increased expression of IGF2R mRNA 6q25.3 Cyclosporine Approved Investigational Vet Approved IL17RB 55540 downregulated Cyclosporine results in decreased expression of IL17RB mRNA 3p21.1 Cyclosporine Approved Investigational Vet Approved INSIG1 3638 upregulated Cyclosporine results in increased expression of INSIG1 mRNA 7q36.3 Cyclosporine Approved Investigational Vet Approved INSIG2 51141 upregulated Cyclosporine results in increased expression of INSIG2 mRNA 2q14.1-q14.2 Cyclosporine Approved Investigational Vet Approved ITFG2 55846 upregulated Cyclosporine results in increased expression of ITFG2 mRNA 12p13.33 Cyclosporine Approved Investigational Vet Approved ITGB1 3688 downregulated Cyclosporine results in decreased expression of ITGB1 mRNA 10p11.22 Cyclosporine Approved Investigational Vet Approved KCNK13 56659 downregulated Cyclosporine results in decreased expression of KCNK13 mRNA 14q32.11 Cyclosporine Approved Investigational Vet Approved KEAP1 9817 upregulated Cyclosporine results in increased expression of KEAP1 mRNA 19p13.2 Cyclosporine Approved Investigational Vet Approved KRT15 3866 upregulated Cyclosporine results in increased expression of KRT15 mRNA 17q21.2 Cyclosporine Approved Investigational Vet Approved KRT19 3880 downregulated Cyclosporine results in decreased expression of KRT19 mRNA 17q21.2 Cyclosporine Approved Investigational Vet Approved LARS 51520 upregulated Cyclosporine results in increased expression of LARS mRNA 5q32 Cyclosporine Approved Investigational Vet Approved LMCD1 29995 downregulated Cyclosporine results in decreased expression of LMCD1 mRNA 3p25.3 Cyclosporine Approved Investigational Vet Approved MAFG 4097 upregulated Cyclosporine results in increased expression of MAFG mRNA 17q25.3 Cyclosporine Approved Investigational Vet Approved MAN1A2 10905 upregulated Cyclosporine results in increased expression of MAN1A2 mRNA 1p12 Cyclosporine Approved Investigational Vet Approved MAPRE2 10982 upregulated Cyclosporine results in increased expression of MAPRE2 mRNA 18q12.1-q12.2 Cyclosporine Approved Investigational Vet Approved MDM2 4193 upregulated Cyclosporine results in increased expression of MDM2 mRNA 12q15 Cyclosporine Approved Investigational Vet Approved ME1 4199 upregulated Cyclosporine results in increased expression of ME1 mRNA 6q14.2 Cyclosporine Approved Investigational Vet Approved MT2A 4502 upregulated Cyclosporine results in increased expression of MT2A mRNA 16q13 Cyclosporine Approved Investigational Vet Approved MTDH 92140 upregulated Cyclosporine results in increased expression of MTDH mRNA 8q22.1 Cyclosporine Approved Investigational Vet Approved MTFP1 51537 upregulated Cyclosporine results in increased expression of MTFP1 mRNA 22q12.2 Cyclosporine Approved Investigational Vet Approved NAMPT 10135 upregulated Cyclosporine results in increased expression of NAMPT mRNA 7q22.3 Cyclosporine Approved Investigational Vet Approved NCAPD2 9918 downregulated Cyclosporine results in decreased expression of NCAPD2 mRNA 12p13.31 Cyclosporine Approved Investigational Vet Approved NEDD9 4739 downregulated Cyclosporine results in decreased expression of NEDD9 mRNA 6p24.2 Cyclosporine Approved Investigational Vet Approved NIN 51199 downregulated Cyclosporine results in decreased expression of NIN mRNA 14q22.1 Cyclosporine Approved Investigational Vet Approved NINJ1 4814 downregulated Cyclosporine results in decreased expression of NINJ1 mRNA 9q22.31 Cyclosporine Approved Investigational Vet Approved NR3C1 2908 upregulated Cyclosporine results in increased expression of NR3C1 mRNA 5q31.3 Cyclosporine Approved Investigational Vet Approved NREP 9315 downregulated Cyclosporine results in decreased expression of NREP mRNA 5q22.1 Cyclosporine Approved Investigational Vet Approved NUAK1 9891 downregulated Cyclosporine results in decreased expression of NUAK1 mRNA 12q23.3 Cyclosporine Approved Investigational Vet Approved OSGIN1 29948 upregulated Cyclosporine results in increased expression of OSGIN1 mRNA 16q23.3 Cyclosporine Approved Investigational Vet Approved OXSM 54995 upregulated Cyclosporine results in increased expression of OXSM mRNA 3p24.2 Cyclosporine Approved Investigational Vet Approved PANK1 53354 downregulated Cyclosporine results in decreased expression of PANK1 mRNA 10q23.31 Cyclosporine Approved Investigational Vet Approved PDE8A 5151 upregulated Cyclosporine results in increased expression of PDE8A mRNA 15q25.3 Cyclosporine Approved Investigational Vet Approved PDE9A 5152 downregulated Cyclosporine results in decreased expression of PDE9A mRNA 21q22.3 Cyclosporine Approved Investigational Vet Approved PDIA5 10954 downregulated Cyclosporine results in decreased expression of PDIA5 mRNA 3q21.1 Cyclosporine Approved Investigational Vet Approved PDK4 5166 downregulated Cyclosporine results in decreased expression of PDK4 mRNA 7q21.3 Cyclosporine Approved Investigational Vet Approved PDLIM1 9124 downregulated Cyclosporine results in decreased expression of PDLIM1 mRNA 10q23.33 Cyclosporine Approved Investigational Vet Approved PFKFB4 5210 upregulated Cyclosporine results in increased expression of PFKFB4 mRNA 3p21.31 Cyclosporine Approved Investigational Vet Approved PHGDH 26227 upregulated Cyclosporine results in increased expression of PHGDH mRNA 1p12 Cyclosporine Approved Investigational Vet Approved PHLDA3 23612 upregulated Cyclosporine results in increased expression of PHLDA3 mRNA 1q32.1 Cyclosporine Approved Investigational Vet Approved PIR 8544 upregulated Cyclosporine results in increased expression of PIR mRNA Xp22.2 Cyclosporine Approved Investigational Vet Approved PMAIP1 5366 upregulated Cyclosporine results in increased expression of PMAIP1 mRNA 18q21.32 Cyclosporine Approved Investigational Vet Approved PMEPA1 56937 downregulated Cyclosporine results in decreased expression of PMEPA1 mRNA 20q13.31 Cyclosporine Approved Investigational Vet Approved POLR3F 10621 upregulated Cyclosporine results in increased expression of POLR3F mRNA 20p11.23 Cyclosporine Approved Investigational Vet Approved PPFIBP1 8496 downregulated Cyclosporine results in decreased expression of PPFIBP1 mRNA 12p11.23, 12p11.22 Cyclosporine Approved Investigational Vet Approved PPP1R15A 23645 upregulated Cyclosporine results in increased expression of PPP1R15A mRNA 19q13.2 Cyclosporine Approved Investigational Vet Approved PRC1 9055 downregulated Cyclosporine results in decreased expression of PRC1 mRNA 15q26.1 Cyclosporine Approved Investigational Vet Approved PRKAB1 5564 downregulated Cyclosporine results in decreased expression of PRKAB1 mRNA 12q24.23 Cyclosporine Approved Investigational Vet Approved PRKAB2 5565 upregulated Cyclosporine results in increased expression of PRKAB2 mRNA 1q21.1 Cyclosporine Approved Investigational Vet Approved PRPS1 5631 upregulated Cyclosporine results in increased expression of PRPS1 mRNA Xq22.3 Cyclosporine Approved Investigational Vet Approved PSAT1 29968 upregulated Cyclosporine results in increased expression of PSAT1 mRNA 9q21.2 Cyclosporine Approved Investigational Vet Approved PYGL 5836 downregulated Cyclosporine results in decreased expression of PYGL mRNA 14q22.1 Cyclosporine Approved Investigational Vet Approved RAB26 25837 downregulated Cyclosporine results in decreased expression of RAB26 mRNA 16p13.3 Cyclosporine Approved Investigational Vet Approved RARA 5914 downregulated Cyclosporine results in decreased expression of RARA mRNA 17q21.2 Cyclosporine Approved Investigational Vet Approved RFFL 117584 upregulated Cyclosporine results in increased expression of RFFL mRNA 17q12 Cyclosporine Approved Investigational Vet Approved RIT1 6016 upregulated Cyclosporine results in increased expression of RIT1 mRNA 1q22 Cyclosporine Approved Investigational Vet Approved RND1 27289 upregulated Cyclosporine results in increased expression of RND1 mRNA 12q13.12 Cyclosporine Approved Investigational Vet Approved RND3 390 upregulated Cyclosporine results in increased expression of RND3 mRNA 2q23.3 Cyclosporine Approved Investigational Vet Approved RNF121 55298 downregulated Cyclosporine results in decreased expression of RNF121 mRNA 11q13.4 Cyclosporine Approved Investigational Vet Approved RPS27L 51065 upregulated Cyclosporine results in increased expression of RPS27L mRNA 15q22.2 Cyclosporine Approved Investigational Vet Approved RRM2B 50484 upregulated Cyclosporine results in increased expression of RRM2B mRNA 8q22.3 Cyclosporine Approved Investigational Vet Approved RRP12 23223 upregulated Cyclosporine results in increased expression of RRP12 mRNA 10q24.1 Cyclosporine Approved Investigational Vet Approved RSL1D1 26156 upregulated Cyclosporine results in increased expression of RSL1D1 mRNA 16p13.13 Cyclosporine Approved Investigational Vet Approved RSRC2 65117 upregulated Cyclosporine results in increased expression of RSRC2 mRNA 12q24.31 Cyclosporine Approved Investigational Vet Approved RXRA 6256 downregulated Cyclosporine results in decreased expression of RXRA mRNA 9q34.2 Cyclosporine Approved Investigational Vet Approved SARM1 23098 downregulated Cyclosporine results in decreased expression of SARM1 mRNA 17q11.2 Cyclosporine Approved Investigational Vet Approved SARS 6301 upregulated Cyclosporine results in increased expression of SARS mRNA 1p13.3 Cyclosporine Approved Investigational Vet Approved SAT1 6303 downregulated Cyclosporine results in decreased expression of SAT1 mRNA Xp22.11 Cyclosporine Approved Investigational Vet Approved SCAMP1 9522 downregulated Cyclosporine results in decreased expression of SCAMP1 mRNA 5q14.1 Cyclosporine Approved Investigational Vet Approved SDF2L1 23753 upregulated Cyclosporine results in increased expression of SDF2L1 mRNA 22q11.21 Cyclosporine Approved Investigational Vet Approved SFN 2810 upregulated Cyclosporine results in increased expression of SFN mRNA 1p36.11 Cyclosporine Approved Investigational Vet Approved SH3TC1 54436 downregulated Cyclosporine results in decreased expression of SH3TC1 mRNA 4p16.1 Cyclosporine Approved Investigational Vet Approved SIK1 150094 upregulated Cyclosporine results in increased expression of SIK1 mRNA 21q22.3 Cyclosporine Approved Investigational Vet Approved SIVA1 10572 downregulated Cyclosporine results in decreased expression of SIVA1 mRNA 14q32.33 Cyclosporine Approved Investigational Vet Approved SLC1A4 6509 upregulated Cyclosporine results in increased expression of SLC1A4 mRNA 2p14 Cyclosporine Approved Investigational Vet Approved SLC1A5 6510 upregulated Cyclosporine results in increased expression of SLC1A5 mRNA 19q13.32 Cyclosporine Approved Investigational Vet Approved SLC25A20 788 downregulated Cyclosporine results in decreased expression of SLC25A20 mRNA 3p21.31 Cyclosporine Approved Investigational Vet Approved SLC27A2 11001 downregulated Cyclosporine results in decreased expression of SLC27A2 mRNA 15q21.2 Cyclosporine Approved Investigational Vet Approved SLC2A1 6513 upregulated Cyclosporine results in increased expression of SLC2A1 mRNA 1p34.2 Cyclosporine Approved Investigational Vet Approved SLC2A11 66035 downregulated Cyclosporine results in decreased expression of SLC2A11 mRNA 22q11.23 Cyclosporine Approved Investigational Vet Approved SLC3A2 6520 upregulated Cyclosporine results in increased expression of SLC3A2 mRNA 11q12.3 Cyclosporine Approved Investigational Vet Approved SLC6A6 6533 downregulated Cyclosporine results in decreased expression of SLC6A6 mRNA 3p25.1 Cyclosporine Approved Investigational Vet Approved SLC6A9 6536 upregulated Cyclosporine results in increased expression of SLC6A9 mRNA 1p34.1 Cyclosporine Approved Investigational Vet Approved SLC7A11 23657 upregulated Cyclosporine results in increased expression of SLC7A11 mRNA 4q28.3 Cyclosporine Approved Investigational Vet Approved SLC7A5 8140 upregulated Cyclosporine results in increased expression of SLC7A5 mRNA 16q24.2 Cyclosporine Approved Investigational Vet Approved SMAP1 60682 upregulated Cyclosporine results in increased expression of SMAP1 mRNA 6q13 Cyclosporine Approved Investigational Vet Approved SORL1 6653 downregulated Cyclosporine results in decreased expression of SORL1 mRNA 11q24.1 Cyclosporine Approved Investigational Vet Approved SPRY1 10252 downregulated Cyclosporine results in decreased expression of SPRY1 mRNA 4q28.1 Cyclosporine Approved Investigational Vet Approved SPSB1 80176 upregulated Cyclosporine results in increased expression of SPSB1 mRNA 1p36.22 Cyclosporine Approved Investigational Vet Approved SQSTM1 8878 upregulated Cyclosporine results in increased expression of SQSTM1 mRNA 5q35.3 Cyclosporine Approved Investigational Vet Approved SRD5A3 79644 downregulated Cyclosporine results in decreased expression of SRD5A3 mRNA 4q12 Cyclosporine Approved Investigational Vet Approved SRXN1 140809 upregulated Cyclosporine results in increased expression of SRXN1 mRNA 20p13 Cyclosporine Approved Investigational Vet Approved STRBP 55342 downregulated Cyclosporine results in decreased expression of STRBP mRNA 9q33.1-q33.3 Cyclosporine Approved Investigational Vet Approved SULF2 55959 downregulated Cyclosporine results in decreased expression of SULF2 mRNA 20q13.12 Cyclosporine Approved Investigational Vet Approved TALDO1 6888 upregulated Cyclosporine results in increased expression of TALDO1 mRNA 11p15.5 Cyclosporine Approved Investigational Vet Approved TBXAS1 6916 downregulated Cyclosporine results in decreased expression of TBXAS1 mRNA 7q34 Cyclosporine Approved Investigational Vet Approved TFAP2A 7020 downregulated Cyclosporine results in decreased expression of TFAP2A mRNA 6p24.3 Cyclosporine Approved Investigational Vet Approved TFE3 7030 upregulated Cyclosporine results in increased expression of TFE3 mRNA Xp11.23 Cyclosporine Approved Investigational Vet Approved TIGAR 57103 upregulated Cyclosporine results in increased expression of TIGAR mRNA 12p13.32 Cyclosporine Approved Investigational Vet Approved TINAG 27283 downregulated Cyclosporine results in decreased expression of TINAG mRNA 6p12.1 Cyclosporine Approved Investigational Vet Approved TMTC2 160335 downregulated Cyclosporine results in decreased expression of TMTC2 mRNA 12q21.31 Cyclosporine Approved Investigational Vet Approved TNFRSF10B 8795 upregulated Cyclosporine results in increased expression of TNFRSF10B mRNA 8p21.3 Cyclosporine Approved Investigational Vet Approved TNFRSF21 27242 downregulated Cyclosporine results in decreased expression of TNFRSF21 mRNA 6p12.3 Cyclosporine Approved Investigational Vet Approved TNFSF9 8744 upregulated Cyclosporine results in increased expression of TNFSF9 mRNA 19p13.3 Cyclosporine Approved Investigational Vet Approved TP53I3 9540 downregulated Cyclosporine results in decreased expression of TP53I3 mRNA 2p23.3 Cyclosporine Approved Investigational Vet Approved TP53TG1 11257 downregulated Cyclosporine results in decreased expression of TP53TG1 mRNA 7q21.12 Cyclosporine Approved Investigational Vet Approved TPCN1 53373 downregulated Cyclosporine results in decreased expression of TPCN1 mRNA 12q24.13 Cyclosporine Approved Investigational Vet Approved TPD52L1 7164 downregulated Cyclosporine results in decreased expression of TPD52L1 mRNA 6q22-q23 Cyclosporine Approved Investigational Vet Approved TROVE2 6738 upregulated Cyclosporine results in increased expression of TROVE2 mRNA 1q31.2 Cyclosporine Approved Investigational Vet Approved TSPAN12 23554 downregulated Cyclosporine results in decreased expression of TSPAN12 mRNA 7q31.31 Cyclosporine Approved Investigational Vet Approved TXN 7295 upregulated Cyclosporine results in increased expression of TXN mRNA 9q31.3 Cyclosporine Approved Investigational Vet Approved TXNRD1 7296 upregulated Cyclosporine results in increased expression of TXNRD1 mRNA 12q23.3 Cyclosporine Approved Investigational Vet Approved UBE2G2 7327 downregulated Cyclosporine results in decreased expression of UBE2G2 mRNA 21q22.3 Cyclosporine Approved Investigational Vet Approved UBE2O 63893 upregulated Cyclosporine results in increased expression of UBE2O mRNA 17q25.1 Cyclosporine Approved Investigational Vet Approved UNKL 64718 upregulated Cyclosporine results in increased expression of UNKL mRNA 16p13.3 Cyclosporine Approved Investigational Vet Approved USP3 9960 upregulated Cyclosporine results in increased expression of USP3 mRNA 15q22.3 Cyclosporine Approved Investigational Vet Approved VDR 7421 downregulated Cyclosporine results in decreased expression of VDR mRNA 12q13.11 Cyclosporine Approved Investigational Vet Approved VTCN1 79679 downregulated Cyclosporine results in decreased expression of VTCN1 mRNA 1p13.1-p12 Cyclosporine Approved Investigational Vet Approved WARS 7453 upregulated Cyclosporine results in increased expression of WARS mRNA 14q32.2 Cyclosporine Approved Investigational Vet Approved WDR7 23335 upregulated Cyclosporine results in increased expression of WDR7 mRNA 18q21.31 Cyclosporine Approved Investigational Vet Approved WWC2 80014 downregulated Cyclosporine results in decreased expression of WWC2 mRNA 4q35.1 Cyclosporine Approved Investigational Vet Approved XBP1 7494 upregulated Cyclosporine results in increased expression of XBP1 mRNA 22q12.1 Cyclosporine Approved Investigational Vet Approved XPC 7508 downregulated Cyclosporine results in decreased expression of XPC mRNA 3p25.1 Cyclosporine Approved Investigational Vet Approved YARS 8565 upregulated Cyclosporine results in increased expression of YARS mRNA 1p35.1 Cyclosporine Approved Investigational Vet Approved YEATS2 55689 upregulated Cyclosporine results in increased expression of YEATS2 mRNA 3q27.1 Cyclosporine Approved Investigational Vet Approved YTHDC2 64848 upregulated Cyclosporine results in increased expression of YTHDC2 mRNA 5q22.2 Cisplatin Approved AARS 16 downregulated Cisplatin results in decreased expression of AARS mRNA 16q22.1 Cisplatin Approved ABCB6 10058 upregulated Cisplatin results in increased expression of ABCB6 mRNA 2q35 Cisplatin Approved ABCG1 9619 downregulated Cisplatin results in decreased expression of ABCG1 mRNA 21q22.3 Cisplatin Approved ABHD4 63874 upregulated Cisplatin results in increased expression of ABHD4 mRNA 14q11.2 Cisplatin Approved ACSL1 2180 downregulated Cisplatin results in decreased expression of ACSL1 mRNA 4q35.1 Cisplatin Approved AGRN 375790 upregulated Cisplatin results in increased expression of AGRN mRNA 1p36.33 Cisplatin Approved AIFM2 84883 downregulated Cisplatin results in decreased expression of AIFM2 mRNA 10q22.1 Cisplatin Approved AK3 50808 upregulated Cisplatin results in increased expression of AK3 mRNA 9p24.1 Cisplatin Approved AK4 205 upregulated Cisplatin results in increased expression of AK4 mRNA 1p31.3 Cisplatin Approved AKR1C2 1646 upregulated Cisplatin results in increased expression of AKR1C2 mRNA 10p15.1 Cisplatin Approved ALDH18A1 5832 downregulated Cisplatin results in decreased expression of ALDH18A1 mRNA 10q24.1 Cisplatin Approved ALDH1A3 220 upregulated Cisplatin results in increased expression of ALDH1A3 mRNA 15q26.3 Cisplatin Approved ALDOA 226 upregulated Cisplatin results in increased expression of ALDOA mRNA 16p11.2 Cisplatin Approved ANGPTL4 51129 upregulated Cisplatin results in increased expression of ANGPTL4 mRNA 19p13.2 Cisplatin Approved ANKRA2 57763 downregulated Cisplatin results in decreased expression of ANKRA2 mRNA 5q13.2 Cisplatin Approved ARHGEF10 9639 downregulated Cisplatin results in decreased expression of ARHGEF10 mRNA 8p23.3 Cisplatin Approved ASTN2 23245 upregulated Cisplatin results in increased expression of ASTN2 mRNA 9q33.1 Cisplatin Approved ATAD2 29028 upregulated Cisplatin results in increased expression of ATAD2 mRNA 8q24.13 Cisplatin Approved ATF3 467 upregulated Cisplatin results in increased expression of ATF3 mRNA 1q32.3 Cisplatin Approved ATXN1 6310 downregulated Cisplatin results in decreased expression of ATXN1 mRNA 6p22.3 Cisplatin Approved AURKB 9212 upregulated Cisplatin results in increased expression of AURKB mRNA 17p13.1 Cisplatin Approved AXL 558 upregulated Cisplatin results in increased expression of AXL mRNA 19q13.2 Cisplatin Approved BAX 581 upregulated Cisplatin results in increased expression of BAX mRNA 19q13.33 Cisplatin Approved BBC3 27113 upregulated Cisplatin results in increased expression of BBC3 mRNA 19q13.32 Cisplatin Approved BCAR3 8412 upregulated Cisplatin results in increased expression of BCAR3 mRNA 1p22.1 Cisplatin Approved BCAT1 586 downregulated Cisplatin results in decreased expression of BCAT1 mRNA 12p12.1 Cisplatin Approved BCAT2 587 upregulated Cisplatin results in increased expression of BCAT2 mRNA 19q13.33 Cisplatin Approved BCL3 602 upregulated Cisplatin results in increased expression of BCL3 mRNA 19q13.32 Cisplatin Approved BEND6 221336 downregulated Cisplatin results in decreased expression of BEND6 mRNA 6p12.1 Cisplatin Approved BRD2 6046 downregulated Cisplatin results in decreased expression of BRD2 mRNA 6p21.32 Cisplatin Approved BTG2 7832 upregulated Cisplatin results in increased expression of BTG2 mRNA 1q32.1 Cisplatin Approved CAMKK2 10645 upregulated Cisplatin results in increased expression of CAMKK2 mRNA 12q24.31 Cisplatin Approved CARS 833 downregulated Cisplatin results in decreased expression of CARS mRNA 11p15.4 Cisplatin Approved CCDC90B 60492 downregulated Cisplatin results in decreased expression of CCDC90B mRNA 11q14.1 Cisplatin Approved CCNE2 9134 upregulated Cisplatin results in increased expression of CCNE2 mRNA 8q22.1 Cisplatin Approved CCNG2 901 downregulated Cisplatin results in decreased expression of CCNG2 mRNA 4q21.1 Cisplatin Approved CDK6 1021 downregulated Cisplatin results in decreased expression of CDK6 mRNA 7q21.2 Cisplatin Approved CDKN1A 1026 upregulated Cisplatin results in increased expression of CDKN1A mRNA 6p21.2 Cisplatin Approved CERS5 91012 upregulated Cisplatin results in increased expression of CERS5 mRNA 12q13.12 Cisplatin Approved CHSY1 22856 downregulated Cisplatin results in decreased expression of CHSY1 mRNA 15q26.3 Cisplatin Approved CLIP4 79745 upregulated Cisplatin results in increased expression of CLIP4 mRNA 2p23.2 Cisplatin Approved CMBL 134147 upregulated Cisplatin results in increased expression of CMBL mRNA 5p15.2 Cisplatin Approved COCH 1690 upregulated Cisplatin results in increased expression of COCH mRNA 14q12 Cisplatin Approved COL4A1 1282 downregulated Cisplatin results in decreased expression of COL4A1 mRNA 13q34 Cisplatin Approved CTDP1 9150 downregulated Cisplatin results in decreased expression of CTDP1 mRNA 18q23 Cisplatin Approved CTSC 1075 upregulated Cisplatin results in increased expression of CTSC mRNA 11q14.2 Cisplatin Approved CTTN 2017 upregulated Cisplatin results in increased expression of CTTN mRNA 11q13.3 Cisplatin Approved CYP1A1 1543 downregulated Cisplatin results in decreased expression of CYP1A1 mRNA 15q24.1 Cisplatin Approved CYP1B1 1545 upregulated Cisplatin results in increased expression of CYP1B1 mRNA 2p22.2 Cisplatin Approved DDB2 1643 upregulated Cisplatin results in increased expression of DDB2 mRNA 11p11.2 Cisplatin Approved DDIT3 1649 upregulated Cisplatin results in increased expression of DDIT3 mRNA 12q13.3 Cisplatin Approved DDIT4 54541 upregulated Cisplatin results in increased expression of DDIT4 mRNA 10q22.1 Cisplatin Approved DDX17 10521 downregulated Cisplatin results in decreased expression of DDX17 mRNA 22q13.1 Cisplatin Approved DDX24 57062 upregulated Cisplatin results in increased expression of DDX24 mRNA 14q32.12 Cisplatin Approved DGKA 1606 upregulated Cisplatin results in increased expression of DGKA mRNA 12q13.2 Cisplatin Approved DLGAP5 9787 downregulated Cisplatin results in decreased expression of DLGAP5 mRNA 14q22.3 Cisplatin Approved DLX1 1745 downregulated Cisplatin results in decreased expression of DLX1 mRNA 2q31.1 Cisplatin Approved DNAJB2 3300 upregulated Cisplatin results in increased expression of DNAJB2 mRNA 2q35 Cisplatin Approved DPM3 54344 upregulated Cisplatin results in increased expression of DPM3 mRNA 1q22 Cisplatin Approved DPP9 91039 upregulated Cisplatin results in increased expression of DPP9 mRNA 19p13.3 Cisplatin Approved DPYSL3 1809 downregulated Cisplatin results in decreased expression of DPYSL3 mRNA 5q32 Cisplatin Approved DUSP22 56940 upregulated Cisplatin results in increased expression of DUSP22 mRNA 6p25.3 Cisplatin Approved DUSP5 1847 upregulated Cisplatin results in increased expression of DUSP5 mRNA 10q25.2 Cisplatin Approved EBLN2 55096 downregulated Cisplatin results in decreased expression of EBLN2 mRNA 3p13 Cisplatin Approved EDA2R 60401 upregulated Cisplatin results in increased expression of EDA2R mRNA Xq12 Cisplatin Approved EFNA1 1942 downregulated Cisplatin results in decreased expression of EFNA1 mRNA 1q22 Cisplatin Approved EIF1 10209 upregulated Cisplatin results in increased expression of EIF1 mRNA 17q21.2 Cisplatin Approved EIF3C 8663 downregulated Cisplatin results in decreased expression of EIF3C mRNA 16p11.2 Cisplatin Approved ELK4 2005 downregulated Cisplatin results in decreased expression of ELK4 mRNA 1q32.1 Cisplatin Approved ENO2 2026 upregulated Cisplatin results in increased expression of ENO2 mRNA 12p13.31 Cisplatin Approved ENOSF1 55556 downregulated Cisplatin results in decreased expression of ENOSF1 mRNA 18p11.32 Cisplatin Approved EP400 57634 downregulated Cisplatin results in decreased expression of EP400 mRNA 12q24.33 Cisplatin Approved EPRS 2058 downregulated Cisplatin results in decreased expression of EPRS mRNA 1q41 Cisplatin Approved EXOC7 23265 upregulated Cisplatin results in increased expression of EXOC7 mRNA 17q25.1 Cisplatin Approved FAM162A 26355 downregulated Cisplatin results in decreased expression of FAM162A mRNA 3q21.1 Cisplatin Approved FAM167A 83648 downregulated Cisplatin results in decreased expression of FAM167A mRNA 8p23.1 Cisplatin Approved FAM210A 125228 upregulated Cisplatin results in increased expression of FAM210A mRNA 18p11.21 Cisplatin Approved FAM212B 55924 upregulated Cisplatin results in increased expression of FAM212B mRNA 1p13.2 Cisplatin Approved FAM214A 56204 downregulated Cisplatin results in decreased expression of FAM214A mRNA 15q21.2-q21.3 Cisplatin Approved FAM84B 157638 upregulated Cisplatin results in increased expression of FAM84B mRNA 8q24.21 Cisplatin Approved FAM89A 375061 upregulated Cisplatin results in increased expression of FAM89A mRNA 1q42.2 Cisplatin Approved FBXO22 26263 upregulated Cisplatin results in increased expression of FBXO22 mRNA 15q24.2 Cisplatin Approved FBXO30 84085 downregulated Cisplatin results in decreased expression of FBXO30 mRNA 6q24.3 Cisplatin Approved FECH 2235 downregulated Cisplatin results in decreased expression of FECH mRNA 18q21.31 Cisplatin Approved FLVCR2 55640 downregulated Cisplatin results in decreased expression of FLVCR2 mRNA 14q24.3 Cisplatin Approved FOSL1 8061 upregulated Cisplatin results in increased expression of FOSL1 mRNA 11q13.1 Cisplatin Approved FOSL2 2355 downregulated Cisplatin results in decreased expression of FOSL2 mRNA 2p23.2 Cisplatin Approved FREM2 341640 downregulated Cisplatin results in decreased expression of FREM2 mRNA 13q13.3 Cisplatin Approved GABARAPL1 23710 upregulated Cisplatin results in increased expression of GABARAPL1 mRNA 12p13.2 Cisplatin Approved GADD45A 1647 upregulated Cisplatin results in increased expression of GADD45A mRNA 1p31.3 Cisplatin Approved GALNT16 57452 downregulated Cisplatin results in decreased expression of GALNT16 mRNA 14q24.1 Cisplatin Approved GARS 2617 upregulated Cisplatin results in increased expression of GARS mRNA 7p14.3 Cisplatin Approved GBE1 2632 upregulated Cisplatin results in increased expression of GBE1 mRNA 3p12.2 Cisplatin Approved GCLC 2729 downregulated Cisplatin results in decreased expression of GCLC mRNA 6p12.1 Cisplatin Approved GCLM 2730 upregulated Cisplatin results in increased expression of GCLM mRNA 1p22.1 Cisplatin Approved GDF15 9518 upregulated Cisplatin results in increased expression of GDF15 mRNA 19p13.11 Cisplatin Approved GOLIM4 27333 downregulated Cisplatin results in decreased expression of GOLIM4 mRNA 3q26.2 Cisplatin Approved GORASP1 64689 upregulated Cisplatin results in increased expression of GORASP1 mRNA 3p22.2 Cisplatin Approved GPAT3 84803 upregulated Cisplatin results in increased expression of GPAT3 mRNA 4q21.23 Cisplatin Approved GPHN 10243 downregulated Cisplatin results in decreased expression of GPHN mRNA 14q23.3 Cisplatin Approved GPNMB 10457 downregulated Cisplatin results in decreased expression of GPNMB mRNA 7p15.3 Cisplatin Approved GPR87 53836 downregulated Cisplatin results in decreased expression of GPR87 mRNA 3q25.1 Cisplatin Approved GSR 2936 upregulated Cisplatin results in increased expression of GSR mRNA 8p12 Cisplatin Approved HERC3 8916 downregulated Cisplatin results in decreased expression of HERC3 mRNA 4q22.1 Cisplatin Approved HIST1H1C 3006 upregulated Cisplatin results in increased expression of HIST1H1C mRNA 6p22.2 Cisplatin Approved HMOX1 3162 upregulated Cisplatin results in increased expression of HMOX1 mRNA 22q12.3 Cisplatin Approved HSPA1B 3304 downregulated Cisplatin results in decreased expression of HSPA1B mRNA 6p21.33 Cisplatin Approved HSPA5 3309 downregulated Cisplatin results in decreased expression of HSPA5 mRNA 9q33.3 Cisplatin Approved IARS 3376 upregulated Cisplatin results in increased expression of IARS mRNA 9q22.31 Cisplatin Approved IDS 3423 downregulated Cisplatin results in decreased expression of IDS mRNA Xq28 Cisplatin Approved ISCU 23479 upregulated Cisplatin results in increased expression of ISCU mRNA 12q23.3 Cisplatin Approved ITFG2 55846 downregulated Cisplatin results in decreased expression of ITFG2 mRNA 12p13.33 Cisplatin Approved ITGB1 3688 upregulated Cisplatin results in increased expression of ITGB1 mRNA 10p11.22 Cisplatin Approved KAT6B 23522 downregulated Cisplatin results in decreased expression of KAT6B mRNA 10q22.2 Cisplatin Approved KDM3A 55818 downregulated Cisplatin results in decreased expression of KDM3A mRNA 2p11.2 Cisplatin Approved KEAP1 9817 upregulated Cisplatin results in increased expression of KEAP1 mRNA 19p13.2 Cisplatin Approved KRT19 3880 upregulated Cisplatin results in increased expression of KRT19 mRNA 17q21.2 Cisplatin Approved LAMA3 3909 upregulated Cisplatin results in increased expression of LAMA3 mRNA 18q11.2 Cisplatin Approved LARS 51520 downregulated Cisplatin results in decreased expression of LARS mRNA 5q32 Cisplatin Approved LTN1 26046 downregulated Cisplatin results in decreased expression of LTN1 mRNA 21q21.3 Cisplatin Approved MAN1A2 10905 downregulated Cisplatin results in decreased expression of MAN1A2 mRNA 1p12 Cisplatin Approved MAP3K8 1326 downregulated Cisplatin results in decreased expression of MAP3K8 mRNA 10p11.23 Cisplatin Approved MDM2 4193 upregulated Cisplatin results in increased expression of MDM2 mRNA 12q15 Cisplatin Approved ME1 4199 downregulated Cisplatin results in decreased expression of ME1 mRNA 6q14.2 Cisplatin Approved MT2A 4502 upregulated Cisplatin results in increased expression of MT2A mRNA 16q13 Cisplatin Approved MTDH 92140 downregulated Cisplatin results in decreased expression of MTDH mRNA 8q22.1 Cisplatin Approved MTFP1 51537 upregulated Cisplatin results in increased expression of MTFP1 mRNA 22q12.2 Cisplatin Approved MXI1 4601 downregulated Cisplatin results in decreased expression of MXI1 mRNA 10q25.2 Cisplatin Approved NARS 4677 downregulated Cisplatin results in decreased expression of NARS mRNA 18q21.31 Cisplatin Approved NEDD9 4739 downregulated Cisplatin results in decreased expression of NEDD9 mRNA 6p24.2 Cisplatin Approved NIN 51199 downregulated Cisplatin results in decreased expression of NIN mRNA 14q22.1 Cisplatin Approved NINJ1 4814 upregulated Cisplatin results in increased expression of NINJ1 mRNA 9q22.31 Cisplatin Approved NQO1 1728 downregulated Cisplatin results in decreased expression of NQO1 mRNA 16q22.1 Cisplatin Approved NR3C1 2908 downregulated Cisplatin results in decreased expression of NR3C1 mRNA 5q31.3 Cisplatin Approved NTPCR 84284 upregulated Cisplatin results in increased expression of NTPCR mRNA 1q42.2 Cisplatin Approved NUAK1 9891 downregulated Cisplatin results in decreased expression of NUAK1 mRNA 12q23.3 Cisplatin Approved OSGIN1 29948 downregulated Cisplatin results in decreased expression of OSGIN1 mRNA 16q23.3 Cisplatin Approved OXSM 54995 upregulated Cisplatin results in increased expression of OXSM mRNA 3p24.2 Cisplatin Approved P4HA1 5033 downregulated Cisplatin results in decreased expression of P4HA1 mRNA 10q22.1 Cisplatin Approved PANK1 53354 downregulated Cisplatin results in decreased expression of PANK1 mRNA 10q23.31 Cisplatin Approved PDE8A 5151 downregulated Cisplatin results in decreased expression of PDE8A mRNA 15q25.3 Cisplatin Approved PDIA5 10954 upregulated Cisplatin results in increased expression of PDIA5 mRNA 3q21.1 Cisplatin Approved PDK1 5163 downregulated Cisplatin results in decreased expression of PDK1 mRNA 2q31.1 Cisplatin Approved PDK4 5166 upregulated Cisplatin results in increased expression of PDK4 mRNA 7q21.3 Cisplatin Approved PDLIM1 9124 upregulated Cisplatin results in increased expression of PDLIM1 mRNA 10q23.33 Cisplatin Approved PFKFB4 5210 downregulated Cisplatin results in decreased expression of PFKFB4 mRNA 3p21.31 Cisplatin Approved PHLDA3 23612 upregulated Cisplatin results in increased expression of PHLDA3 mRNA 1q32.1 Cisplatin Approved PIP5K1C 23396 downregulated Cisplatin results in decreased expression of PIP5K1C mRNA 19p13.3 Cisplatin Approved PMAIP1 5366 downregulated Cisplatin results in decreased expression of PMAIP1 mRNA 18q21.32 Cisplatin Approved PMEPA1 56937 upregulated Cisplatin results in increased expression of PMEPA1 mRNA 20q13.31 Cisplatin Approved POLR3F 10621 downregulated Cisplatin results in decreased expression of POLR3F mRNA 20p11.23 Cisplatin Approved PPFIBP1 8496 upregulated Cisplatin results in increased expression of PPFIBP1 mRNA 12p11.23, 12p11.22 Cisplatin Approved PPIG 9360 downregulated Cisplatin results in decreased expression of PPIG mRNA 2q31.1 Cisplatin Approved PPP4R2 151987 downregulated Cisplatin results in decreased expression of PPP4R2 mRNA 3p13 Cisplatin Approved PRC1 9055 upregulated Cisplatin results in increased expression of PRC1 mRNA 15q26.1 Cisplatin Approved PRDM1 639 downregulated Cisplatin results in decreased expression of PRDM1 mRNA 6q21 Cisplatin Approved PRKAB1 5564 upregulated Cisplatin results in increased expression of PRKAB1 mRNA 12q24.23 Cisplatin Approved PRKAB2 5565 downregulated Cisplatin results in decreased expression of PRKAB2 mRNA 1q21.1 Cisplatin Approved PSAT1 29968 upregulated Cisplatin results in increased expression of PSAT1 mRNA 9q21.2 Cisplatin Approved PYCR1 5831 upregulated Cisplatin results in increased expression of PYCR1 mRNA 17q25.3 Cisplatin Approved PYGL 5836 downregulated Cisplatin results in decreased expression of PYGL mRNA 14q22.1 Cisplatin Approved RAB31 11031 upregulated Cisplatin results in increased expression of RAB31 mRNA 18p11.22 Cisplatin Approved RARA 5914 downregulated Cisplatin results in decreased expression of RARA mRNA 17q21.2 Cisplatin Approved RFFL 117584 upregulated Cisplatin results in increased expression of RFFL mRNA 17q12 Cisplatin Approved RIT1 6016 upregulated Cisplatin results in increased expression of RIT1 mRNA 1q22 Cisplatin Approved RLF 6018 upregulated Cisplatin results in increased expression of RLF mRNA 1p34.2 Cisplatin Approved RNF121 55298 downregulated Cisplatin results in decreased expression of RNF121 mRNA 11q13.4 Cisplatin Approved RPS27L 51065 upregulated Cisplatin results in increased expression of RPS27L mRNA 15q22.2 Cisplatin Approved RRM2B 50484 downregulated Cisplatin results in decreased expression of RRM2B mRNA 8q22.3 Cisplatin Approved RRP12 23223 upregulated Cisplatin results in increased expression of RRP12 mRNA 10q24.1 Cisplatin Approved RSL1D1 26156 upregulated Cisplatin results in increased expression of RSL1D1 mRNA 16p13.13 Cisplatin Approved RSRC2 65117 downregulated Cisplatin results in decreased expression of RSRC2 mRNA 12q24.31 Cisplatin Approved RUNX1 861 downregulated Cisplatin results in decreased expression of RUNX1 mRNA 21q22.12 Cisplatin Approved SARS 6301 upregulated Cisplatin results in increased expression of SARS mRNA 1p13.3 Cisplatin Approved SERTAD1 29950 upregulated Cisplatin results in increased expression of SERTAD1 mRNA 19q13.1-q13.2 Cisplatin Approved SESN1 27244 upregulated Cisplatin results in increased expression of SESN1 mRNA 6q21 Cisplatin Approved SFN 2810 upregulated Cisplatin results in increased expression of SFN mRNA 1p36.11 Cisplatin Approved SIAH2 6478 upregulated Cisplatin results in increased expression of SIAH2 mRNA 3q25.1 Cisplatin Approved SIVA1 10572 upregulated Cisplatin results in increased expression of SIVA1 mRNA 14q32.33 Cisplatin Approved SLC12A8 84561 downregulated Cisplatin results in decreased expression of SLC12A8 mRNA 3q21.2 Cisplatin Approved SLC1A4 6509 downregulated Cisplatin results in decreased expression of SLC1A4 mRNA 2p14 Cisplatin Approved SLC1A5 6510 upregulated Cisplatin results in increased expression of SLC1A5 mRNA 19q13.32 Cisplatin Approved SLC1A7 6512 upregulated Cisplatin results in increased expression of SLC1A7 mRNA 1p32.3 Cisplatin Approved SLC25A20 788 upregulated Cisplatin results in increased expression of SLC25A20 mRNA 3p21.31 Cisplatin Approved SLC2A1 6513 upregulated Cisplatin results in increased expression of SLC2A1 mRNA 1p34.2 Cisplatin Approved SLC2A11 66035 upregulated Cisplatin results in increased expression of SLC2A11 mRNA 22q11.23 Cisplatin Approved SLC3A2 6520 upregulated Cisplatin results in increased expression of SLC3A2 mRNA 11q12.3 Cisplatin Approved SLC6A9 6536 downregulated Cisplatin results in decreased expression of SLC6A9 mRNA 1p34.1 Cisplatin Approved SLC7A1 6541 upregulated Cisplatin results in increased expression of SLC7A1 mRNA 13q12.3 Cisplatin Approved SLC7A5 8140 upregulated Cisplatin results in increased expression of SLC7A5 mRNA 16q24.2 Cisplatin Approved SON 6651 downregulated Cisplatin results in decreased expression of SON mRNA 21q22.11 Cisplatin Approved SORL1 6653 downregulated Cisplatin results in decreased expression of SORL1 mRNA 11q24.1 Cisplatin Approved SPRY1 10252 upregulated Cisplatin results in increased expression of SPRY1 mRNA 4q28.1 Cisplatin Approved SPSB1 80176 upregulated Cisplatin results in increased expression of SPSB1 mRNA 1p36.22 Cisplatin Approved SRD5A3 79644 downregulated Cisplatin results in decreased expression of SRD5A3 mRNA 4q12 Cisplatin Approved SRXN1 140809 upregulated Cisplatin results in increased expression of SRXN1 mRNA 20p13 Cisplatin Approved SULF2 55959 downregulated Cisplatin results in decreased expression of SULF2 mRNA 20q13.12 Cisplatin Approved TALDO1 6888 upregulated Cisplatin results in increased expression of TALDO1 mRNA 11p15.5 Cisplatin Approved TAOK1 57551 upregulated Cisplatin results in increased expression of TAOK1 mRNA 17q11.2 Cisplatin Approved TARS 6897 downregulated Cisplatin results in decreased expression of TARS mRNA 5p13.3 Cisplatin Approved TBXAS1 6916 upregulated Cisplatin results in increased expression of TBXAS1 mRNA 7q34 Cisplatin Approved TFAP2A 7020 downregulated Cisplatin results in decreased expression of TFAP2A mRNA 6p24.3 Cisplatin Approved TIGAR 57103 upregulated Cisplatin results in increased expression of TIGAR mRNA 12p13.32 Cisplatin Approved TIPARP 25976 downregulated Cisplatin results in decreased expression of TIPARP mRNA 3q25.31 Cisplatin Approved TMEM45A 55076 downregulated Cisplatin results in decreased expression of TMEM45A mRNA 3q12.2 Cisplatin Approved TMEM45B 120224 downregulated Cisplatin results in decreased expression of TMEM45B mRNA 11q24.3 Cisplatin Approved TMEM94 9772 downregulated Cisplatin results in decreased expression of TMEM94 mRNA 17q25.1 Cisplatin Approved TMTC2 160335 downregulated Cisplatin results in decreased expression of TMTC2 mRNA 12q21.31 Cisplatin Approved TNFAIP8 25816 upregulated Cisplatin results in increased expression of TNFAIP8 mRNA 5q23.1 Cisplatin Approved TNFRSF10B 8795 upregulated Cisplatin results in increased expression of TNFRSF10B mRNA 8p21.3 Cisplatin Approved TNFSF9 8744 upregulated Cisplatin results in increased expression of TNFSF9 mRNA 19p13.3 Cisplatin Approved TOP1 7150 upregulated Cisplatin results in increased expression of TOP1 mRNA 20q12 Cisplatin Approved TP53I3 9540 upregulated Cisplatin results in increased expression of TP53I3 mRNA 2p23.3 Cisplatin Approved TP53INP1 94241 upregulated Cisplatin results in increased expression of TP53INP1 mRNA 8q22.1 Cisplatin Approved TP53TG1 11257 upregulated Cisplatin results in increased expression of TP53TG1 mRNA 7q21.12 Cisplatin Approved TPCN1 53373 downregulated Cisplatin results in decreased expression of TPCN1 mRNA 12q24.13 Cisplatin Approved TRAFD1 10906 upregulated Cisplatin results in increased expression of TRAFD1 mRNA 12q24.13 Cisplatin Approved TRIAP1 51499 upregulated Cisplatin results in increased expression of TRIAP1 mRNA 12q24.31 Cisplatin Approved TROVE2 6738 downregulated Cisplatin results in decreased expression of TROVE2 mRNA 1q31.2 Cisplatin Approved TSPAN12 23554 downregulated Cisplatin results in decreased expression of TSPAN12 mRNA 7q31.31 Cisplatin Approved TXN 7295 upregulated Cisplatin results in increased expression of TXN mRNA 9q31.3 Cisplatin Approved TXNRD1 7296 upregulated Cisplatin results in increased expression of TXNRD1 mRNA 12q23.3 Cisplatin Approved UBE2G2 7327 upregulated Cisplatin results in increased expression of UBE2G2 mRNA 21q22.3 Cisplatin Approved VARS 7407 upregulated Cisplatin results in increased expression of VARS mRNA 6p21.33 Cisplatin Approved WARS 7453 upregulated Cisplatin results in increased expression of WARS mRNA 14q32.2 Cisplatin Approved WWC2 80014 downregulated Cisplatin results in decreased expression of WWC2 mRNA 4q35.1 Cisplatin Approved XBP1 7494 downregulated Cisplatin results in decreased expression of XBP1 mRNA 22q12.1 Cisplatin Approved XPC 7508 upregulated Cisplatin results in increased expression of XPC mRNA 3p25.1 Cisplatin Approved YARS 8565 downregulated Cisplatin results in decreased expression of YARS mRNA 1p35.1 Cisplatin Approved YTHDC2 64848 downregulated Cisplatin results in decreased expression of YTHDC2 mRNA 5q22.2 Cisplatin Approved ZMAT3 64393 upregulated Cisplatin results in increased expression of ZMAT3 mRNA 3q26.32 Cisplatin Approved ZNF561 93134 downregulated Cisplatin results in decreased expression of ZNF561 mRNA 19p13.2 Fenofibrate Approved ACSL1 2180 upregulated Fenofibrate results in increased expression of ACSL1 mRNA 4q35.1 Fenofibrate Approved ADCY1 107 downregulated Fenofibrate results in decreased expression of ADCY1 mRNA 7p12.3 Fenofibrate Approved AIFM2 84883 upregulated Fenofibrate results in increased expression of AIFM2 mRNA 10q22.1 Fenofibrate Approved AKR1C2 1646 upregulated Fenofibrate results in increased expression of AKR1C2 mRNA 10p15.1 Fenofibrate Approved ANGPTL4 51129 upregulated Fenofibrate results in increased expression of ANGPTL4 mRNA 19p13.2 Fenofibrate Approved ANKRA2 57763 upregulated Fenofibrate results in increased expression of ANKRA2 mRNA 5q13.2 Fenofibrate Approved ARFGEF2 10564 upregulated Fenofibrate results in increased expression of ARFGEF2 mRNA 20q13.13 Fenofibrate Approved ASNS 440 upregulated Fenofibrate results in increased expression of ASNS mRNA 7q21.3 Fenofibrate Approved ATF3 467 upregulated Fenofibrate results in increased expression of ATF3 mRNA 1q32.3 Fenofibrate Approved BCAT1 586 downregulated Fenofibrate results in decreased expression of BCAT1 mRNA 12p12.1 Fenofibrate Approved BCAT2 587 upregulated Fenofibrate results in increased expression of BCAT2 mRNA 19q13.33 Fenofibrate Approved BCL3 602 downregulated Fenofibrate results in decreased expression of BCL3 mRNA 19q13.32 Fenofibrate Approved BHLHE40 8553 downregulated Fenofibrate results in decreased expression of BHLHE40 mRNA 3p26.1 Fenofibrate Approved BMF 90427 upregulated Fenofibrate results in increased expression of BMF mRNA 15q15.1 Fenofibrate Approved CCNG2 901 downregulated Fenofibrate results in decreased expression of CCNG2 mRNA 4q21.1 Fenofibrate Approved CTH 1491 upregulated Fenofibrate results in increased expression of CTH mRNA 1p31.1 Fenofibrate Approved DDIT3 1649 upregulated Fenofibrate results in increased expression of DDIT3 mRNA 12q13.3 Fenofibrate Approved DDIT4 54541 downregulated Fenofibrate results in decreased expression of DDIT4 mRNA 10q22.1 Fenofibrate Approved DHX37 57647 upregulated Fenofibrate results in increased expression of DHX37 mRNA 12q24.31 Fenofibrate Approved DUSP5 1847 upregulated Fenofibrate results in increased expression of DUSP5 mRNA 10q25.2 Fenofibrate Approved EIF1 10209 upregulated Fenofibrate results in increased expression of EIF1 mRNA 17q21.2 Fenofibrate Approved ELK4 2005 upregulated Fenofibrate results in increased expression of ELK4 mRNA 1q32.1 Fenofibrate Approved ENO1 2023 upregulated Fenofibrate results in increased expression of ENO1 mRNA 1p36.23 Fenofibrate Approved ENTPD7 57089 downregulated Fenofibrate results in decreased expression of ENTPD7 mRNA 10q24.2 Fenofibrate Approved EPRS 2058 upregulated Fenofibrate results in increased expression of EPRS mRNA 1q41 Fenofibrate Approved FAM89A 375061 upregulated Fenofibrate results in increased expression of FAM89A mRNA 1q42.2 Fenofibrate Approved FAS 355 downregulated Fenofibrate results in decreased expression of FAS mRNA 10q23.31 Fenofibrate Approved GARS 2617 upregulated Fenofibrate results in increased expression of GARS mRNA 7p14.3 Fenofibrate Approved GBE1 2632 upregulated Fenofibrate results in increased expression of GBE1 mRNA 3p12.2 Fenofibrate Approved GCLM 2730 upregulated Fenofibrate results in increased expression of GCLM mRNA 1p22.1 Fenofibrate Approved GCNT3 9245 upregulated Fenofibrate results in increased expression of GCNT3 mRNA 15q22.2 Fenofibrate Approved GDF15 9518 upregulated Fenofibrate results in increased expression of GDF15 mRNA 19p13.11 Fenofibrate Approved GPAT3 84803 upregulated Fenofibrate results in increased expression of GPAT3 mRNA 4q21.23 Fenofibrate Approved GPHN 10243 upregulated Fenofibrate results in increased expression of GPHN mRNA 14q23.3 Fenofibrate Approved HERC3 8916 upregulated Fenofibrate results in increased expression of HERC3 mRNA 4q22.1 Fenofibrate Approved HIST1H1C 3006 downregulated Fenofibrate results in decreased expression of HIST1H1C mRNA 6p22.2 Fenofibrate Approved HMOX1 3162 upregulated Fenofibrate results in increased expression of HMOX1 mRNA 22q12.3 Fenofibrate Approved IARS 3376 upregulated Fenofibrate results in increased expression of IARS mRNA 9q22.31 Fenofibrate Approved ITFG2 55846 upregulated Fenofibrate results in increased expression of ITFG2 mRNA 12p13.33 Fenofibrate Approved KCNK13 56659 upregulated Fenofibrate results in increased expression of KCNK13 mRNA 14q32.11 Fenofibrate Approved LARS 51520 upregulated Fenofibrate results in increased expression of LARS mRNA 5q32 Fenofibrate Approved MAFG 4097 upregulated Fenofibrate results in increased expression of MAFG mRNA 17q25.3 Fenofibrate Approved NEDD9 4739 downregulated Fenofibrate results in decreased expression of NEDD9 mRNA 6p24.2 Fenofibrate Approved NREP 9315 downregulated Fenofibrate results in decreased expression of NREP mRNA 5q22.1 Fenofibrate Approved NUAK1 9891 downregulated Fenofibrate results in decreased expression of NUAK1 mRNA 12q23.3 Fenofibrate Approved ORAI3 93129 downregulated Fenofibrate results in decreased expression of ORAI3 mRNA 16p11.2 Fenofibrate Approved PANK1 53354 upregulated Fenofibrate results in increased expression of PANK1 mRNA 10q23.31 Fenofibrate Approved PDK4 5166 upregulated Fenofibrate results in increased expression of PDK4 mRNA 7q21.3 Fenofibrate Approved PHGDH 26227 upregulated Fenofibrate results in increased expression of PHGDH mRNA 1p12 Fenofibrate Approved PLIN2 123 upregulated Fenofibrate results in increased expression of PLIN2 mRNA 9p22.1 Fenofibrate Approved PODXL 5420 downregulated Fenofibrate results in decreased expression of PODXL mRNA 7q32.3 Fenofibrate Approved PPP1R15A 23645 upregulated Fenofibrate results in increased expression of PPP1R15A mRNA 19q13.2 Fenofibrate Approved RAB31 11031 downregulated Fenofibrate results in decreased expression of RAB31 mRNA 18p11.22 Fenofibrate Approved RARA 5914 downregulated Fenofibrate results in decreased expression of RARA mRNA 17q21.2 Fenofibrate Approved RXRA 6256 downregulated Fenofibrate results in decreased expression of RXRA mRNA 9q34.2 Fenofibrate Approved SH3TC1 54436 upregulated Fenofibrate results in increased expression of SH3TC1 mRNA 4p16.1 Fenofibrate Approved SIK1 150094 upregulated Fenofibrate results in increased expression of SIK1 mRNA 21q22.3 Fenofibrate Approved SLC1A7 6512 upregulated Fenofibrate results in increased expression of SLC1A7 mRNA 1p32.3 Fenofibrate Approved SLC25A20 788 upregulated Fenofibrate results in increased expression of SLC25A20 mRNA 3p21.31 Fenofibrate Approved SLC3A2 6520 upregulated Fenofibrate results in increased expression of SLC3A2 mRNA 11q12.3 Fenofibrate Approved SLC6A9 6536 upregulated Fenofibrate results in increased expression of SLC6A9 mRNA 1p34.1 Fenofibrate Approved SLC7A1 6541 upregulated Fenofibrate results in increased expression of SLC7A1 mRNA 13q12.3 Fenofibrate Approved SLC7A5 8140 upregulated Fenofibrate results in increased expression of SLC7A5 mRNA 16q24.2 Fenofibrate Approved SLCO2B1 11309 downregulated Fenofibrate results in decreased expression of SLCO2B1 mRNA 11q13 Fenofibrate Approved SORL1 6653 downregulated Fenofibrate results in decreased expression of SORL1 mRNA 11q24.1 Fenofibrate Approved SRXN1 140809 upregulated Fenofibrate results in increased expression of SRXN1 mRNA 20p13 Fenofibrate Approved STRBP 55342 upregulated Fenofibrate results in increased expression of STRBP mRNA 9q33.1-q33.3 Fenofibrate Approved SULF2 55959 downregulated Fenofibrate results in decreased expression of SULF2 mRNA 20q13.12 Fenofibrate Approved TFE3 7030 upregulated Fenofibrate results in increased expression of TFE3 mRNA Xp11.23 Fenofibrate Approved TNFRSF10B 8795 upregulated Fenofibrate results in increased expression of TNFRSF10B mRNA 8p21.3 Fenofibrate Approved TNFRSF21 27242 upregulated Fenofibrate results in increased expression of TNFRSF21 mRNA 6p12.3 Fenofibrate Approved TP53I3 9540 downregulated Fenofibrate results in decreased expression of TP53I3 mRNA 2p23.3 Fenofibrate Approved TP53INP1 94241 downregulated Fenofibrate results in decreased expression of TP53INP1 mRNA 8q22.1 Fenofibrate Approved TRIAP1 51499 downregulated Fenofibrate results in decreased expression of TRIAP1 mRNA 12q24.31 Fenofibrate Approved TROVE2 6738 downregulated Fenofibrate results in decreased expression of TROVE2 mRNA 1q31.2 Fenofibrate Approved TXNRD1 7296 upregulated Fenofibrate results in increased expression of TXNRD1 mRNA 12q23.3 Fenofibrate Approved VARS 7407 upregulated Fenofibrate results in increased expression of VARS mRNA 6p21.33 Fenofibrate Approved YARS 8565 upregulated Fenofibrate results in increased expression of YARS mRNA 1p35.1 Ibuprofen Approved ABCG1 9619 upregulated Ibuprofen results in increased expression of ABCG1 mRNA 21q22.3 Ibuprofen Approved ABHD4 63874 upregulated Ibuprofen results in increased expression of ABHD4 mRNA 14q11.2 Ibuprofen Approved ACSL1 2180 upregulated Ibuprofen results in increased expression of ACSL1 mRNA 4q35.1 Ibuprofen Approved ADCY1 107 downregulated Ibuprofen results in decreased expression of ADCY1 mRNA 7p12.3 Ibuprofen Approved AIFM2 84883 upregulated Ibuprofen results in increased expression of AIFM2 mRNA 10q22.1 Ibuprofen Approved AK4 205 downregulated Ibuprofen results in decreased expression of AK4 mRNA 1p31.3 Ibuprofen Approved ALDOA 226 upregulated Ibuprofen results in increased expression of ALDOA mRNA 16p11.2 Ibuprofen Approved AMBP 259 downregulated Ibuprofen results in decreased expression of AMBP mRNA 9q32 Ibuprofen Approved ANGPTL4 51129 upregulated Ibuprofen results in increased expression of ANGPTL4 mRNA 19p13.2 Ibuprofen Approved ARFGEF2 10564 upregulated Ibuprofen results in increased expression of ARFGEF2 mRNA 20q13.13 Ibuprofen Approved ASNS 440 upregulated Ibuprofen results in increased expression of ASNS mRNA 7q21.3 Ibuprofen Approved ATXN1 6310 upregulated Ibuprofen results in increased expression of ATXN1 mRNA 6p22.3 Ibuprofen Approved BCAT2 587 upregulated Ibuprofen results in increased expression of BCAT2 mRNA 19q13.33 Ibuprofen Approved CCNE2 9134 upregulated Ibuprofen results in increased expression of CCNE2 mRNA 8q22.1 Ibuprofen Approved CDK6 1021 downregulated Ibuprofen results in decreased expression of CDK6 mRNA 7q21.2 Ibuprofen Approved CMBL 134147 downregulated Ibuprofen results in decreased expression of CMBL mRNA 5p15.2 Ibuprofen Approved COCH 1690 downregulated Ibuprofen results in decreased expression of COCH mRNA 14q12 Ibuprofen Approved CTSC 1075 downregulated Ibuprofen results in decreased expression of CTSC mRNA 11q14.2 Ibuprofen Approved CYP1A2 1544 downregulated Ibuprofen results in decreased expression of CYP1A2 mRNA 15q24.1 Ibuprofen Approved DHX37 57647 upregulated Ibuprofen results in increased expression of DHX37 mRNA 12q24.31 Ibuprofen Approved DNAJB2 3300 upregulated Ibuprofen results in increased expression of DNAJB2 mRNA 2q35 Ibuprofen Approved DPP9 91039 upregulated Ibuprofen results in increased expression of DPP9 mRNA 19p13.3 Ibuprofen Approved DUSP22 56940 upregulated Ibuprofen results in increased expression of DUSP22 mRNA 6p25.3 Ibuprofen Approved DUSP5 1847 upregulated Ibuprofen results in increased expression of DUSP5 mRNA 10q25.2 Ibuprofen Approved ELF4 2000 upregulated Ibuprofen results in increased expression of ELF4 mRNA Xq26.1 Ibuprofen Approved ELK4 2005 upregulated Ibuprofen results in increased expression of ELK4 mRNA 1q32.1 Ibuprofen Approved ENO1 2023 upregulated Ibuprofen results in increased expression of ENO1 mRNA 1p36.23 Ibuprofen Approved EPRS 2058 upregulated Ibuprofen results in increased expression of EPRS mRNA 1q41 Ibuprofen Approved FABP4 2167 upregulated Ibuprofen results in increased expression of FABP4 mRNA 8q21.13 Ibuprofen Approved FAM210B 116151 downregulated Ibuprofen results in decreased expression of FAM210B mRNA 20q13.2 Ibuprofen Approved FAM89A 375061 upregulated Ibuprofen results in increased expression of FAM89A mRNA 1q42.2 Ibuprofen Approved FAS 355 downregulated Ibuprofen results in decreased expression of FAS mRNA 10q23.31 Ibuprofen Approved GBE1 2632 upregulated Ibuprofen results in increased expression of GBE1 mRNA 3p12.2 Ibuprofen Approved GCLM 2730 upregulated Ibuprofen results in increased expression of GCLM mRNA 1p22.1 Ibuprofen Approved GCNT3 9245 upregulated Ibuprofen results in increased expression of GCNT3 mRNA 15q22.2 Ibuprofen Approved GDF15 9518 upregulated Ibuprofen results in increased expression of GDF15 mRNA 19p13.11 Ibuprofen Approved GOT1 2805 upregulated Ibuprofen results in increased expression of GOT1 mRNA 10q24.2 Ibuprofen Approved GPAT3 84803 upregulated Ibuprofen results in increased expression of GPAT3 mRNA 4q21.23 Ibuprofen Approved HIST1H1C 3006 downregulated Ibuprofen results in decreased expression of HIST1H1C mRNA 6p22.2 Ibuprofen Approved HRASLS2 54979 upregulated Ibuprofen results in increased expression of HRASLS2 mRNA 11q12.3 Ibuprofen Approved HSPA5 3309 downregulated Ibuprofen results in decreased expression of HSPA5 mRNA 9q33.3 Ibuprofen Approved IARS 3376 upregulated Ibuprofen results in increased expression of IARS mRNA 9q22.31 Ibuprofen Approved IDS 3423 upregulated Ibuprofen results in increased expression of IDS mRNA Xq28 Ibuprofen Approved INSIG1 3638 upregulated Ibuprofen results in increased expression of INSIG1 mRNA 7q36.3 Ibuprofen Approved LAMA3 3909 downregulated Ibuprofen results in decreased expression of LAMA3 mRNA 18q11.2 Ibuprofen Approved LARS 51520 upregulated Ibuprofen results in increased expression of LARS mRNA 5q32 Ibuprofen Approved MTFP1 51537 upregulated Ibuprofen results in increased expression of MTFP1 mRNA 22q12.2 Ibuprofen Approved NAMPT 10135 upregulated Ibuprofen results in increased expression of NAMPT mRNA 7q22.3 Ibuprofen Approved NEDD9 4739 downregulated Ibuprofen results in decreased expression of NEDD9 mRNA 6p24.2 Ibuprofen Approved NFE2L2 4780 upregulated Ibuprofen results in increased expression of NFE2L2 mRNA 2q31.2 Ibuprofen Approved NR3C1 2908 downregulated Ibuprofen results in decreased expression of NR3C1 mRNA 5q31.3 Ibuprofen Approved NUAK1 9891 downregulated Ibuprofen results in decreased expression of NUAK1 mRNA 12q23.3 Ibuprofen Approved PANK1 53354 upregulated Ibuprofen results in increased expression of PANK1 mRNA 10q23.31 Ibuprofen Approved PCLO 27445 upregulated Ibuprofen results in increased expression of PCLO mRNA 7q21.11 Ibuprofen Approved PDK4 5166 upregulated Ibuprofen results in increased expression of PDK4 mRNA 7q21.3 Ibuprofen Approved PDLIM1 9124 downregulated Ibuprofen results in decreased expression of PDLIM1 mRNA 10q23.33 Ibuprofen Approved PLIN2 123 upregulated Ibuprofen results in increased expression of PLIN2 mRNA 9p22.1 Ibuprofen Approved PPP1R15A 23645 upregulated Ibuprofen results in increased expression of PPP1R15A mRNA 19q13.2 Ibuprofen Approved PRKAB2 5565 downregulated Ibuprofen results in decreased expression of PRKAB2 mRNA 1q21.1 Ibuprofen Approved RARA 5914 downregulated Ibuprofen results in decreased expression of RARA mRNA 17q21.2 Ibuprofen Approved RRP12 23223 upregulated Ibuprofen results in increased expression of RRP12 mRNA 10q24.1 Ibuprofen Approved RSL1D1 26156 upregulated Ibuprofen results in increased expression of RSL1D1 mRNA 16p13.13 Ibuprofen Approved RSRC2 65117 upregulated Ibuprofen results in increased expression of RSRC2 mRNA 12q24.31 Ibuprofen Approved RXRA 6256 downregulated Ibuprofen results in decreased expression of RXRA mRNA 9q34.2 Ibuprofen Approved SFN 2810 upregulated Ibuprofen results in increased expression of SFN mRNA 1p36.11 Ibuprofen Approved SH3TC1 54436 upregulated Ibuprofen results in increased expression of SH3TC1 mRNA 4p16.1 Ibuprofen Approved SIK1 150094 upregulated Ibuprofen results in increased expression of SIK1 mRNA 21q22.3 Ibuprofen Approved SLC16A6 9120 upregulated Ibuprofen results in increased expression of SLC16A6 mRNA 17q24.2 Ibuprofen Approved SLC1A4 6509 upregulated Ibuprofen results in increased expression of SLC1A4 mRNA 2p14 Ibuprofen Approved SLC1A7 6512 upregulated Ibuprofen results in increased expression of SLC1A7 mRNA 1p32.3 Ibuprofen Approved SLC2A1 6513 upregulated Ibuprofen results in increased expression of SLC2A1 mRNA 1p34.2 Ibuprofen Approved SLC3A2 6520 upregulated Ibuprofen results in increased expression of SLC3A2 mRNA 11q12.3 Ibuprofen Approved SLC6A9 6536 upregulated Ibuprofen results in increased expression of SLC6A9 mRNA 1p34.1 Ibuprofen Approved SLC7A1 6541 upregulated Ibuprofen results in increased expression of SLC7A1 mRNA 13q12.3 Ibuprofen Approved SLC7A11 23657 upregulated Ibuprofen results in increased expression of SLC7A11 mRNA 4q28.3 Ibuprofen Approved SLC7A5 8140 upregulated Ibuprofen results in increased expression of SLC7A5 mRNA 16q24.2 Ibuprofen Approved SLCO2B1 11309 downregulated Ibuprofen results in decreased expression of SLCO2B1 mRNA 11q13 Ibuprofen Approved SORL1 6653 downregulated Ibuprofen results in decreased expression of SORL1 mRNA 11q24.1 Ibuprofen Approved SRXN1 140809 upregulated Ibuprofen results in increased expression of SRXN1 mRNA 20p13 Ibuprofen Approved STRBP 55342 upregulated Ibuprofen results in increased expression of STRBP mRNA 9q33.1-q33.3 Ibuprofen Approved SULF2 55959 downregulated Ibuprofen results in decreased expression of SULF2 mRNA 20q13.12 Ibuprofen Approved TFE3 7030 upregulated Ibuprofen results in increased expression of TFE3 mRNA Xp11.23 Ibuprofen Approved TNFAIP8 25816 downregulated Ibuprofen results in decreased expression of TNFAIP8 mRNA 5q23.1 Ibuprofen Approved TP53INP1 94241 downregulated Ibuprofen results in decreased expression of TP53INP1 mRNA 8q22.1 Ibuprofen Approved TPD52L1 7164 upregulated Ibuprofen results in increased expression of TPD52L1 mRNA 6q22-q23 Ibuprofen Approved VARS 7407 upregulated Ibuprofen results in increased expression of VARS mRNA 6p21.33 Ibuprofen Approved VWCE 220001 downregulated Ibuprofen results in decreased expression of VWCE mRNA 11q12.2 Ibuprofen Approved WDR81 124997 upregulated Ibuprofen results in increased expression of WDR81 mRNA 17p13.3 Ibuprofen Approved YARS 8565 upregulated Ibuprofen results in increased expression of YARS mRNA 1p35.1 Ibuprofen Approved ZMAT3 64393 upregulated Ibuprofen results in increased expression of ZMAT3 mRNA 3q26.32 Ifosfamide Approved ABCB6 10058 upregulated Ifosfamide results in increased expression of ABCB6 mRNA 2q35 Ifosfamide Approved ABCB9 23457 upregulated Ifosfamide results in increased expression of ABCB9 mRNA 12q24.31 Ifosfamide Approved ABCG1 9619 downregulated Ifosfamide results in decreased expression of ABCG1 mRNA 21q22.3 Ifosfamide Approved ABHD4 63874 upregulated Ifosfamide results in increased expression of ABHD4 mRNA 14q11.2 Ifosfamide Approved ACSL1 2180 downregulated Ifosfamide results in decreased expression of ACSL1 mRNA 4q35.1 Ifosfamide Approved AGRN 375790 upregulated Ifosfamide results in increased expression of AGRN mRNA 1p36.33 Ifosfamide Approved AK4 205 upregulated Ifosfamide results in increased expression of AK4 mRNA 1p31.3 Ifosfamide Approved AKR1C2 1646 upregulated Ifosfamide results in increased expression of AKR1C2 mRNA 10p15.1 Ifosfamide Approved ALDH1A3 220 upregulated Ifosfamide results in increased expression of ALDH1A3 mRNA 15q26.3 Ifosfamide Approved ALDOA 226 upregulated Ifosfamide results in increased expression of ALDOA mRNA 16p11.2 Ifosfamide Approved ANKRA2 57763 downregulated Ifosfamide results in decreased expression of ANKRA2 mRNA 5q13.2 Ifosfamide Approved ASNS 440 upregulated Ifosfamide results in increased expression of ASNS mRNA 7q21.3 Ifosfamide Approved ATXN1 6310 downregulated Ifosfamide results in decreased expression of ATXN1 mRNA 6p22.3 Ifosfamide Approved AURKB 9212 upregulated Ifosfamide results in increased expression of AURKB mRNA 17p13.1 Ifosfamide Approved AXL 558 upregulated Ifosfamide results in increased expression of AXL mRNA 19q13.2 Ifosfamide Approved BAX 581 upregulated Ifosfamide results in increased expression of BAX mRNA 19q13.33 Ifosfamide Approved BCAT1 586 downregulated Ifosfamide results in decreased expression of BCAT1 mRNA 12p12.1 Ifosfamide Approved BHLHE40 8553 upregulated Ifosfamide results in increased expression of BHLHE40 mRNA 3p26.1 Ifosfamide Approved BNIP3 664 downregulated Ifosfamide results in decreased expression of BNIP3 mRNA 10q26.3 Ifosfamide Approved BRD2 6046 downregulated Ifosfamide results in decreased expression of BRD2 mRNA 6p21.32 Ifosfamide Approved BTG2 7832 upregulated Ifosfamide results in increased expression of BTG2 mRNA 1q32.1 Ifosfamide Approved CAMKK2 10645 upregulated Ifosfamide results in increased expression of CAMKK2 mRNA 12q24.31 Ifosfamide Approved CARS 833 downregulated Ifosfamide results in decreased expression of CARS mRNA 11p15.4 Ifosfamide Approved CCDC90B 60492 downregulated Ifosfamide results in decreased expression of CCDC90B mRNA 11q14.1 Ifosfamide Approved CCNE2 9134 upregulated Ifosfamide results in increased expression of CCNE2 mRNA 8q22.1 Ifosfamide Approved CCNG2 901 downregulated Ifosfamide results in decreased expression of CCNG2 mRNA 4q21.1 Ifosfamide Approved CDKN1A 1026 upregulated Ifosfamide results in increased expression of CDKN1A mRNA 6p21.2 Ifosfamide Approved CERS5 91012 upregulated Ifosfamide results in increased expression of CERS5 mRNA 12q13.12 Ifosfamide Approved CMBL 134147 upregulated Ifosfamide results in increased expression of CMBL mRNA 5p15.2 Ifosfamide Approved CTDP1 9150 downregulated Ifosfamide results in decreased expression of CTDP1 mRNA 18q23 Ifosfamide Approved CTSC 1075 upregulated Ifosfamide results in increased expression of CTSC mRNA 11q14.2 Ifosfamide Approved CTTN 2017 upregulated Ifosfamide results in increased expression of CTTN mRNA 11q13.3 Ifosfamide Approved CYP1A1 1543 downregulated Ifosfamide results in decreased expression of CYP1A1 mRNA 15q24.1 Ifosfamide Approved CYP1A2 1544 upregulated Ifosfamide results in increased expression of CYP1A2 mRNA 15q24.1 Ifosfamide Approved CYP1B1 1545 downregulated Ifosfamide results in decreased expression of CYP1B1 mRNA 2p22.2 Ifosfamide Approved DDIT3 1649 upregulated Ifosfamide results in increased expression of DDIT3 mRNA 12q13.3 Ifosfamide Approved DDIT4 54541 upregulated Ifosfamide results in increased expression of DDIT4 mRNA 10q22.1 Ifosfamide Approved DDX17 10521 downregulated Ifosfamide results in decreased expression of DDX17 mRNA 22q13.1 Ifosfamide Approved DGKA 1606 upregulated Ifosfamide results in increased expression of DGKA mRNA 12q13.2 Ifosfamide Approved DLX1 1745 downregulated Ifosfamide results in decreased expression of DLX1 mRNA 2q31.1 Ifosfamide Approved DNAJB2 3300 upregulated Ifosfamide results in increased expression of DNAJB2 mRNA 2q35 Ifosfamide Approved DNAJB9 4189 upregulated Ifosfamide results in increased expression of DNAJB9 mRNA 7q31.1 Ifosfamide Approved DNMBP 23268 upregulated Ifosfamide results in increased expression of DNMBP mRNA 10q24.2 Ifosfamide Approved DPM3 54344 upregulated Ifosfamide results in increased expression of DPM3 mRNA 1q22 Ifosfamide Approved DUSP22 56940 upregulated Ifosfamide results in increased expression of DUSP22 mRNA 6p25.3 Ifosfamide Approved EFNA1 1942 downregulated Ifosfamide results in decreased expression of EFNA1 mRNA 1q22 Ifosfamide Approved EIF1 10209 upregulated Ifosfamide results in increased expression of EIF1 mRNA 17q21.2 Ifosfamide Approved EIF3C 8663 downregulated Ifosfamide results in decreased expression of EIF3C mRNA 16p11.2 Ifosfamide Approved ELF4 2000 upregulated Ifosfamide results in increased expression of ELF4 mRNA Xq26.1 Ifosfamide Approved ELK4 2005 downregulated Ifosfamide results in decreased expression of ELK4 mRNA 1q32.1 Ifosfamide Approved ENO2 2026 upregulated Ifosfamide results in increased expression of ENO2 mRNA 12p13.31 Ifosfamide Approved ENOSF1 55556 downregulated Ifosfamide results in decreased expression of ENOSF1 mRNA 18p11.32 Ifosfamide Approved EP400 57634 downregulated Ifosfamide results in decreased expression of EP400 mRNA 12q24.33 Ifosfamide Approved EXOC7 23265 upregulated Ifosfamide results in increased expression of EXOC7 mRNA 17q25.1 Ifosfamide Approved FABP3 2170 downregulated Ifosfamide results in decreased expression of FABP3 mRNA 1p35.2 Ifosfamide Approved FAM162A 26355 downregulated Ifosfamide results in decreased expression of FAM162A mRNA 3q21.1 Ifosfamide Approved FAM210B 116151 downregulated Ifosfamide results in decreased expression of FAM210B mRNA 20q13.2 Ifosfamide Approved FAM212B 55924 upregulated Ifosfamide results in increased expression of FAM212B mRNA 1p13.2 Ifosfamide Approved FAM214A 56204 downregulated Ifosfamide results in decreased expression of FAM214A mRNA 15q21.2-q21.3 Ifosfamide Approved FAM89A 375061 upregulated Ifosfamide results in increased expression of FAM89A mRNA 1q42.2 Ifosfamide Approved FBXO22 26263 upregulated Ifosfamide results in increased expression of FBXO22 mRNA 15q24.2 Ifosfamide Approved FBXO30 84085 downregulated Ifosfamide results in decreased expression of FBXO30 mRNA 6q24.3 Ifosfamide Approved FECH 2235 downregulated Ifosfamide results in decreased expression of FECH mRNA 18q21.31 Ifosfamide Approved FLVCR2 55640 downregulated Ifosfamide results in decreased expression of FLVCR2 mRNA 14q24.3 Ifosfamide Approved FOSL1 8061 upregulated Ifosfamide results in increased expression of FOSL1 mRNA 11q13.1 Ifosfamide Approved GARS 2617 upregulated Ifosfamide results in increased expression of GARS mRNA 7p14.3 Ifosfamide Approved GCLC 2729 downregulated Ifosfamide results in decreased expression of GCLC mRNA 6p12.1 Ifosfamide Approved GCLM 2730 upregulated Ifosfamide results in increased expression of GCLM mRNA 1p22.1 Ifosfamide Approved GDF15 9518 upregulated Ifosfamide results in increased expression of GDF15 mRNA 19p13.11 Ifosfamide Approved GPAT3 84803 upregulated Ifosfamide results in increased expression of GPAT3 mRNA 4q21.23 Ifosfamide Approved GPR87 53836 downregulated Ifosfamide results in decreased expression of GPR87 mRNA 3q25.1 Ifosfamide Approved GPR88 54112 upregulated Ifosfamide results in increased expression of GPR88 mRNA 1p21.2 Ifosfamide Approved GSR 2936 upregulated Ifosfamide results in increased expression of GSR mRNA 8p12 Ifosfamide Approved HERC3 8916 downregulated Ifosfamide results in decreased expression of HERC3 mRNA 4q22.1 Ifosfamide Approved HSPA1B 3304 upregulated Ifosfamide results in increased expression of HSPA1B mRNA 6p21.33 Ifosfamide Approved IARS 3376 upregulated Ifosfamide results in increased expression of IARS mRNA 9q22.31 Ifosfamide Approved IDS 3423 downregulated Ifosfamide results in decreased expression of IDS mRNA Xq28 Ifosfamide Approved IGF2R 3482 upregulated Ifosfamide results in increased expression of IGF2R mRNA 6q25.3 Ifosfamide Approved INSIG2 51141 upregulated Ifosfamide results in increased expression of INSIG2 mRNA 2q14.1-q14.2 Ifosfamide Approved ITFG2 55846 downregulated Ifosfamide results in decreased expression of ITFG2 mRNA 12p13.33 Ifosfamide Approved KAT6B 23522 downregulated Ifosfamide results in decreased expression of KAT6B mRNA 10q22.2 Ifosfamide Approved KDM3A 55818 downregulated Ifosfamide results in decreased expression of KDM3A mRNA 2p11.2 Ifosfamide Approved KEAP1 9817 upregulated Ifosfamide results in increased expression of KEAP1 mRNA 19p13.2 Ifosfamide Approved KRT15 3866 upregulated Ifosfamide results in increased expression of KRT15 mRNA 17q21.2 Ifosfamide Approved KRT19 3880 upregulated Ifosfamide results in increased expression of KRT19 mRNA 17q21.2 Ifosfamide Approved LAMA3 3909 upregulated Ifosfamide results in increased expression of LAMA3 mRNA 18q11.2 Ifosfamide Approved LMCD1 29995 downregulated Ifosfamide results in decreased expression of LMCD1 mRNA 3p25.3 Ifosfamide Approved LTN1 26046 downregulated Ifosfamide results in decreased expression of LTN1 mRNA 21q21.3 Ifosfamide Approved MAFG 4097 upregulated Ifosfamide results in increased expression of MAFG mRNA 17q25.3 Ifosfamide Approved MDM2 4193 upregulated Ifosfamide results in increased expression of MDM2 mRNA 12q15 Ifosfamide Approved ME1 4199 downregulated Ifosfamide results in decreased expression of ME1 mRNA 6q14.2 Ifosfamide Approved MT2A 4502 upregulated Ifosfamide results in increased expression of MT2A mRNA 16q13 Ifosfamide Approved MTDH 92140 downregulated Ifosfamide results in decreased expression of MTDH mRNA 8q22.1 Ifosfamide Approved MTFP1 51537 upregulated Ifosfamide results in increased expression of MTFP1 mRNA 22q12.2 Ifosfamide Approved MXI1 4601 downregulated Ifosfamide results in decreased expression of MXI1 mRNA 10q25.2 Ifosfamide Approved NCAPD2 9918 upregulated Ifosfamide results in increased expression of NCAPD2 mRNA 12p13.31 Ifosfamide Approved NEDD9 4739 downregulated Ifosfamide results in decreased expression of NEDD9 mRNA 6p24.2 Ifosfamide Approved NIN 51199 downregulated Ifosfamide results in decreased expression of NIN mRNA 14q22.1 Ifosfamide Approved NPY1R 4886 upregulated Ifosfamide results in increased expression of NPY1R mRNA 4q32.2 Ifosfamide Approved NQO1 1728 downregulated Ifosfamide results in decreased expression of NQO1 mRNA 16q22.1 Ifosfamide Approved NTPCR 84284 upregulated Ifosfamide results in increased expression of NTPCR mRNA 1q42.2 Ifosfamide Approved NUAK1 9891 downregulated Ifosfamide results in decreased expression of NUAK1 mRNA 12q23.3 Ifosfamide Approved OSGIN1 29948 downregulated Ifosfamide results in decreased expression of OSGIN1 mRNA 16q23.3 Ifosfamide Approved P4HA1 5033 downregulated Ifosfamide results in decreased expression of P4HA1 mRNA 10q22.1 Ifosfamide Approved PANK1 53354 downregulated Ifosfamide results in decreased expression of PANK1 mRNA 10q23.31 Ifosfamide Approved PDE8A 5151 downregulated Ifosfamide results in decreased expression of PDE8A mRNA 15q25.3 Ifosfamide Approved PDIA5 10954 upregulated Ifosfamide results in increased expression of PDIA5 mRNA 3q21.1 Ifosfamide Approved PDK1 5163 downregulated Ifosfamide results in decreased expression of PDK1 mRNA 2q31.1 Ifosfamide Approved PHGDH 26227 upregulated Ifosfamide results in increased expression of PHGDH mRNA 1p12 Ifosfamide Approved PHLDA3 23612 upregulated Ifosfamide results in increased expression of PHLDA3 mRNA 1q32.1 Ifosfamide Approved PIDD1 55367 downregulated Ifosfamide results in decreased expression of PIDD1 mRNA 11p15.5 Ifosfamide Approved PMEPA1 56937 upregulated Ifosfamide results in increased expression of PMEPA1 mRNA 20q13.31 Ifosfamide Approved PODXL 5420 downregulated Ifosfamide results in decreased expression of PODXL mRNA 7q32.3 Ifosfamide Approved PPFIBP1 8496 upregulated Ifosfamide results in increased expression of PPFIBP1 mRNA 12p11.23, 12p11.22 Ifosfamide Approved PPIG 9360 downregulated Ifosfamide results in decreased expression of PPIG mRNA 2q31.1 Ifosfamide Approved PPM1D 8493 downregulated Ifosfamide results in decreased expression of PPM1D mRNA 17q23.3 Ifosfamide Approved PRC1 9055 upregulated Ifosfamide results in increased expression of PRC1 mRNA 15q26.1 Ifosfamide Approved PRDM1 639 downregulated Ifosfamide results in decreased expression of PRDM1 mRNA 6q21 Ifosfamide Approved PSAT1 29968 upregulated Ifosfamide results in increased expression of PSAT1 mRNA 9q21.2 Ifosfamide Approved PSPC1 55269 downregulated Ifosfamide results in decreased expression of PSPC1 mRNA 13q12.11 Ifosfamide Approved PYCR1 5831 upregulated Ifosfamide results in increased expression of PYCR1 mRNA 17q25.3 Ifosfamide Approved PYGL 5836 downregulated Ifosfamide results in decreased expression of PYGL mRNA 14q22.1 Ifosfamide Approved RAB31 11031 upregulated Ifosfamide results in increased expression of RAB31 mRNA 18p11.22 Ifosfamide Approved RFFL 117584 upregulated Ifosfamide results in increased expression of RFFL mRNA 17q12 Ifosfamide Approved RIT1 6016 upregulated Ifosfamide results in increased expression of RIT1 mRNA 1q22 Ifosfamide Approved RLF 6018 upregulated Ifosfamide results in increased expression of RLF mRNA 1p34.2 Ifosfamide Approved RNF121 55298 downregulated Ifosfamide results in decreased expression of RNF121 mRNA 11q13.4 Ifosfamide Approved RPS27L 51065 upregulated Ifosfamide results in increased expression of RPS27L mRNA 15q22.2 Ifosfamide Approved RRM2B 50484 downregulated Ifosfamide results in decreased expression of RRM2B mRNA 8q22.3 Ifosfamide Approved RRP12 23223 upregulated Ifosfamide results in increased expression of RRP12 mRNA 10q24.1 Ifosfamide Approved RSRC2 65117 downregulated Ifosfamide results in decreased expression of RSRC2 mRNA 12q24.31 Ifosfamide Approved SARS 6301 upregulated Ifosfamide results in increased expression of SARS mRNA 1p13.3 Ifosfamide Approved SERTAD1 29950 upregulated Ifosfamide results in increased expression of SERTAD1 mRNA 19q13.1-q13.2 Ifosfamide Approved SESN1 27244 upregulated Ifosfamide results in increased expression of SESN1 mRNA 6q21 Ifosfamide Approved SFN 2810 upregulated Ifosfamide results in increased expression of SFN mRNA 1p36.11 Ifosfamide Approved SH3TC1 54436 downregulated Ifosfamide results in decreased expression of SH3TC1 mRNA 4p16.1 Ifosfamide Approved SIAH2 6478 upregulated Ifosfamide results in increased expression of SIAH2 mRNA 3q25.1 Ifosfamide Approved SIPA1L2 57568 downregulated Ifosfamide results in decreased expression of SIPA1L2 mRNA 1q42.2 Ifosfamide Approved SIVA1 10572 upregulated Ifosfamide results in increased expression of SIVA1 mRNA 14q32.33 Ifosfamide Approved SLC12A8 84561 downregulated Ifosfamide results in decreased expression of SLC12A8 mRNA 3q21.2 Ifosfamide Approved SLC1A5 6510 upregulated Ifosfamide results in increased expression of SLC1A5 mRNA 19q13.32 Ifosfamide Approved SLC25A20 788 upregulated Ifosfamide results in increased expression of SLC25A20 mRNA 3p21.31 Ifosfamide Approved SLC2A1 6513 upregulated Ifosfamide results in increased expression of SLC2A1 mRNA 1p34.2 Ifosfamide Approved SLC3A2 6520 upregulated Ifosfamide results in increased expression of SLC3A2 mRNA 11q12.3 Ifosfamide Approved SLC6A9 6536 downregulated Ifosfamide results in decreased expression of SLC6A9 mRNA 1p34.1 Ifosfamide Approved SLC7A5 8140 upregulated Ifosfamide results in increased expression of SLC7A5 mRNA 16q24.2 Ifosfamide Approved SON 6651 downregulated Ifosfamide results in decreased expression of SON mRNA 21q22.11 Ifosfamide Approved SPSB1 80176 upregulated Ifosfamide results in increased expression of SPSB1 mRNA 1p36.22 Ifosfamide Approved SQSTM1 8878 upregulated Ifosfamide results in increased expression of SQSTM1 mRNA 5q35.3 Ifosfamide Approved SRD5A3 79644 downregulated Ifosfamide results in decreased expression of SRD5A3 mRNA 4q12 Ifosfamide Approved SRXN1 140809 upregulated Ifosfamide results in increased expression of SRXN1 mRNA 20p13 Ifosfamide Approved SULF2 55959 downregulated Ifosfamide results in decreased expression of SULF2 mRNA 20q13.12 Ifosfamide Approved TALDO1 6888 upregulated Ifosfamide results in increased expression of TALDO1 mRNA 11p15.5 Ifosfamide Approved TARS 6897 downregulated Ifosfamide results in decreased expression of TARS mRNA 5p13.3 Ifosfamide Approved TBXAS1 6916 upregulated Ifosfamide results in increased expression of TBXAS1 mRNA 7q34 Ifosfamide Approved TFAP2A 7020 downregulated Ifosfamide results in decreased expression of TFAP2A mRNA 6p24.3 Ifosfamide Approved THBS2 7058 downregulated Ifosfamide results in decreased expression of THBS2 mRNA 6q27 Ifosfamide Approved TIGAR 57103 upregulated Ifosfamide results in increased expression of TIGAR mRNA 12p13.32 Ifosfamide Approved TIMM17B 10245 downregulated Ifosfamide results in decreased expression of TIMM17B mRNA Xp11.23 Ifosfamide Approved TLR4 7099 upregulated Ifosfamide results in increased expression of TLR4 mRNA 9q33.1 Ifosfamide Approved TMEM94 9772 downregulated Ifosfamide results in decreased expression of TMEM94 mRNA 17q25.1 Ifosfamide Approved TMTC2 160335 downregulated Ifosfamide results in decreased expression of TMTC2 mRNA 12q21.31 Ifosfamide Approved TNFAIP8 25816 upregulated Ifosfamide results in increased expression of TNFAIP8 mRNA 5q23.1 Ifosfamide Approved TNFRSF10B 8795 upregulated Ifosfamide results in increased expression of TNFRSF10B mRNA 8p21.3 Ifosfamide Approved TNFSF9 8744 upregulated Ifosfamide results in increased expression of TNFSF9 mRNA 19p13.3 Ifosfamide Approved TOP1 7150 upregulated Ifosfamide results in increased expression of TOP1 mRNA 20q12 Ifosfamide Approved TP53I3 9540 upregulated Ifosfamide results in increased expression of TP53I3 mRNA 2p23.3 Ifosfamide Approved TP53INP1 94241 upregulated Ifosfamide results in increased expression of TP53INP1 mRNA 8q22.1 Ifosfamide Approved TP53TG1 11257 upregulated Ifosfamide results in increased expression of TP53TG1 mRNA 7q21.12 Ifosfamide Approved TRAFD1 10906 upregulated Ifosfamide results in increased expression of TRAFD1 mRNA 12q24.13 Ifosfamide Approved TRIAP1 51499 upregulated Ifosfamide results in increased expression of TRIAP1 mRNA 12q24.31 Ifosfamide Approved TROVE2 6738 downregulated Ifosfamide results in decreased expression of TROVE2 mRNA 1q31.2 Ifosfamide Approved TSPAN12 23554 downregulated Ifosfamide results in decreased expression of TSPAN12 mRNA 7q31.31 Ifosfamide Approved TXN 7295 upregulated Ifosfamide results in increased expression of TXN mRNA 9q31.3 Ifosfamide Approved TXNRD1 7296 upregulated Ifosfamide results in increased expression of TXNRD1 mRNA 12q23.3 Ifosfamide Approved UBE2G2 7327 upregulated Ifosfamide results in increased expression of UBE2G2 mRNA 21q22.3 Ifosfamide Approved UNKL 64718 upregulated Ifosfamide results in increased expression of UNKL mRNA 16p13.3 Ifosfamide Approved USP3 9960 upregulated Ifosfamide results in increased expression of USP3 mRNA 15q22.3 Ifosfamide Approved VARS 7407 upregulated Ifosfamide results in increased expression of VARS mRNA 6p21.33 Ifosfamide Approved WARS 7453 upregulated Ifosfamide results in increased expression of WARS mRNA 14q32.2 Ifosfamide Approved WDR63 126820 downregulated Ifosfamide results in decreased expression of WDR63 mRNA 1p22.3 Ifosfamide Approved WWC2 80014 downregulated Ifosfamide results in decreased expression of WWC2 mRNA 4q35.1 Ifosfamide Approved XPC 7508 upregulated Ifosfamide results in increased expression of XPC mRNA 3p25.1 Ifosfamide Approved ZMAT3 64393 upregulated Ifosfamide results in increased expression of ZMAT3 mRNA 3q26.32 Ifosfamide Approved ZNF561 93134 downregulated Ifosfamide results in decreased expression of ZNF561 mRNA 19p13.2 Metformin Approved CCNG2 901 downregulated Metformin results in decreased expression of CCNG2 mRNA 4q21.1 Metformin Approved DUSP5 1847 upregulated Metformin results in increased expression of DUSP5 mRNA 10q25.2 Metformin Approved ELK4 2005 upregulated Metformin results in increased expression of ELK4 mRNA 1q32.1 Metformin Approved GCLM 2730 upregulated Metformin results in increased expression of GCLM mRNA 1p22.1 Metformin Approved GCNT3 9245 upregulated Metformin results in increased expression of GCNT3 mRNA 15q22.2 Metformin Approved GPAT3 84803 upregulated Metformin results in increased expression of GPAT3 mRNA 4q21.23 Metformin Approved HIST1H1C 3006 downregulated Metformin results in decreased expression of HIST1H1C mRNA 6p22.2 Metformin Approved HRASLS2 54979 upregulated Metformin results in increased expression of HRASLS2 mRNA 11q12.3 Metformin Approved PPP1R15A 23645 upregulated Metformin results in increased expression of PPP1R15A mRNA 19q13.2 Metformin Approved SLCO2B1 11309 downregulated Metformin results in decreased expression of SLCO2B1 mRNA 11q13 Metformin Approved TP53INP1 94241 downregulated Metformin results in decreased expression of TP53INP1 mRNA 8q22.1 Oxygen Approved Vet Approved AARS 16 downregulated Oxygen deficiency results in decreased expression of AARS mRNA 16q22.1 Oxygen Approved Vet Approved ABCB6 10058 upregulated Oxygen deficiency results in increased expression of ABCB6 mRNA 2q35 Oxygen Approved Vet Approved ABCB9 23457 upregulated Oxygen deficiency results in increased expression of ABCB9 mRNA 12q24.31 Oxygen Approved Vet Approved ABCG1 9619 downregulated Oxygen deficiency results in decreased expression of ABCG1 mRNA 21q22.3 Oxygen Approved Vet Approved ABHD4 63874 downregulated Oxygen deficiency results in decreased expression of ABHD4 mRNA 14q11.2 Oxygen Approved Vet Approved ACSL1 2180 downregulated Oxygen deficiency results in decreased expression of ACSL1 mRNA 4q35.1 Oxygen Approved Vet Approved AGRN 375790 upregulated Oxygen deficiency results in increased expression of AGRN mRNA 1p36.33 Oxygen Approved Vet Approved AIFM2 84883 downregulated Oxygen deficiency results in decreased expression of AIFM2 mRNA 10q22.1 Oxygen Approved Vet Approved AK3 50808 downregulated Oxygen deficiency results in decreased expression of AK3 mRNA 9p24.1 Oxygen Approved Vet Approved AK4 205 upregulated Oxygen deficiency results in increased expression of AK4 mRNA 1p31.3 Oxygen Approved Vet Approved AKR1C2 1646 downregulated Oxygen deficiency results in decreased expression of AKR1C2 mRNA 10p15.1 Oxygen Approved Vet Approved ALDH18A1 5832 upregulated Oxygen deficiency results in increased expression of ALDH18A1 mRNA 10q24.1 Oxygen Approved Vet Approved ALDOA 226 upregulated Oxygen deficiency results in increased expression of ALDOA mRNA 16p11.2 Oxygen Approved Vet Approved ALS2CL 259173 downregulated Oxygen deficiency results in decreased expression of ALS2CL mRNA 3p21.31 Oxygen Approved Vet Approved ANGPTL4 51129 upregulated Oxygen deficiency results in increased expression of ANGPTL4 mRNA 19p13.2 Oxygen Approved Vet Approved ANKRA2 57763 downregulated Oxygen deficiency results in decreased expression of ANKRA2 mRNA 5q13.2 Oxygen Approved Vet Approved ARFGEF2 10564 upregulated Oxygen deficiency results in increased expression of ARFGEF2 mRNA 20q13.13 Oxygen Approved Vet Approved ARHGEF10 9639 upregulated Oxygen deficiency results in increased expression of ARHGEF10 mRNA 8p23.3 Oxygen Approved Vet Approved ARL1 400 upregulated Oxygen deficiency results in increased expression of ARL1 mRNA 12q23.2 Oxygen Approved Vet Approved ARL10 285598 upregulated Oxygen deficiency results in increased expression of ARL10 mRNA 5q35.2 Oxygen Approved Vet Approved ASNS 440 downregulated Oxygen deficiency results in decreased expression of ASNS mRNA 7q21.3 Oxygen Approved Vet Approved ASTN2 23245 upregulated Oxygen deficiency results in increased expression of ASTN2 mRNA 9q33.1 Oxygen Approved Vet Approved ATAD2 29028 downregulated Oxygen deficiency results in decreased expression of ATAD2 mRNA 8q24.13 Oxygen Approved Vet Approved ATF3 467 upregulated Oxygen deficiency results in increased expression of ATF3 mRNA 1q32.3 Oxygen Approved Vet Approved ATXN1 6310 upregulated Oxygen deficiency results in increased expression of ATXN1 mRNA 6p22.3 Oxygen Approved Vet Approved AXL 558 upregulated Oxygen deficiency results in increased expression of AXL mRNA 19q13.2 Oxygen Approved Vet Approved BBC3 27113 upregulated Oxygen deficiency results in increased expression of BBC3 mRNA 19q13.32 Oxygen Approved Vet Approved BCAR3 8412 upregulated Oxygen deficiency results in increased expression of BCAR3 mRNA 1p22.1 Oxygen Approved Vet Approved BCL3 602 downregulated Oxygen deficiency results in decreased expression of BCL3 mRNA 19q13.32 Oxygen Approved Vet Approved BEND5 79656 upregulated Oxygen deficiency results in increased expression of BEND5 mRNA 1p33 Oxygen Approved Vet Approved BEND6 221336 downregulated Oxygen deficiency results in decreased expression of BEND6 mRNA 6p12.1 Oxygen Approved Vet Approved BHLHE40 8553 upregulated Oxygen deficiency results in increased expression of BHLHE40 mRNA 3p26.1 Oxygen Approved Vet Approved BMF 90427 downregulated Oxygen deficiency results in decreased expression of BMF mRNA 15q15.1 Oxygen Approved Vet Approved BNIP3 664 upregulated Oxygen deficiency results in increased expression of BNIP3 mRNA 10q26.3 Oxygen Approved Vet Approved BRD2 6046 downregulated Oxygen deficiency results in decreased expression of BRD2 mRNA 6p21.32 Oxygen Approved Vet Approved BTG2 7832 downregulated Oxygen deficiency results in decreased expression of BTG2 mRNA 1q32.1 Oxygen Approved Vet Approved CARS 833 downregulated Oxygen deficiency results in decreased expression of CARS mRNA 11p15.4 Oxygen Approved Vet Approved CCNE2 9134 downregulated Oxygen deficiency results in decreased expression of CCNE2 mRNA 8q22.1 Oxygen Approved Vet Approved CCNG2 901 upregulated Oxygen deficiency results in increased expression of CCNG2 mRNA 4q21.1 Oxygen Approved Vet Approved CDK6 1021 upregulated Oxygen deficiency results in increased expression of CDK6 mRNA 7q21.2 Oxygen Approved Vet Approved CDKN1A 1026 upregulated Oxygen deficiency results in increased expression of CDKN1A mRNA 6p21.2 Oxygen Approved Vet Approved CERS5 91012 upregulated Oxygen deficiency results in increased expression of CERS5 mRNA 12q13.12 Oxygen Approved Vet Approved CHSY1 22856 upregulated Oxygen deficiency results in increased expression of CHSY1 mRNA 15q26.3 Oxygen Approved Vet Approved CMBL 134147 downregulated Oxygen deficiency results in decreased expression of CMBL mRNA 5p15.2 Oxygen Approved Vet Approved COCH 1690 downregulated Oxygen deficiency results in decreased expression of COCH mRNA 14q12 Oxygen Approved Vet Approved COL4A1 1282 downregulated Oxygen deficiency results in decreased expression of COL4A1 mRNA 13q34 Oxygen Approved Vet Approved CP 1356 upregulated Oxygen deficiency results in increased expression of CP mRNA 3q24-q25.1 Oxygen Approved Vet Approved CTDP1 9150 downregulated Oxygen deficiency results in decreased expression of CTDP1 mRNA 18q23 Oxygen Approved Vet Approved CTH 1491 downregulated Oxygen deficiency results in decreased expression of CTH mRNA 1p31.1 Oxygen Approved Vet Approved CTSC 1075 downregulated Oxygen deficiency results in decreased expression of CTSC mRNA 11q14.2 Oxygen Approved Vet Approved CTTN 2017 downregulated Oxygen deficiency results in decreased expression of CTTN mRNA 11q13.3 Oxygen Approved Vet Approved CYP1B1 1545 downregulated Oxygen deficiency results in decreased expression of CYP1B1 mRNA 2p22.2 Oxygen Approved Vet Approved DDB2 1643 upregulated Oxygen deficiency results in increased expression of DDB2 mRNA 11p11.2 Oxygen Approved Vet Approved DDIT3 1649 upregulated Oxygen deficiency results in increased expression of DDIT3 mRNA 12q13.3 Oxygen Approved Vet Approved DDIT4 54541 upregulated Oxygen deficiency results in increased expression of DDIT4 mRNA 10q22.1 Oxygen Approved Vet Approved DDX17 10521 upregulated Oxygen deficiency results in increased expression of DDX17 mRNA 22q13.1 Oxygen Approved Vet Approved DGKA 1606 upregulated Oxygen deficiency results in increased expression of DGKA mRNA 12q13.2 Oxygen Approved Vet Approved DLL1 28514 upregulated Oxygen deficiency results in increased expression of DLL1 mRNA 6q27 Oxygen Approved Vet Approved DLX1 1745 downregulated Oxygen deficiency results in decreased expression of DLX1 mRNA 2q31.1 Oxygen Approved Vet Approved DNAJB2 3300 upregulated Oxygen deficiency results in increased expression of DNAJB2 mRNA 2q35 Oxygen Approved Vet Approved DNAJB9 4189 upregulated Oxygen deficiency results in increased expression of DNAJB9 mRNA 7q31.1 Oxygen Approved Vet Approved DNMBP 23268 upregulated Oxygen deficiency results in increased expression of DNMBP mRNA 10q24.2 Oxygen Approved Vet Approved DPM3 54344 downregulated Oxygen deficiency results in decreased expression of DPM3 mRNA 1q22 Oxygen Approved Vet Approved DPP9 91039 upregulated Oxygen deficiency results in increased expression of DPP9 mRNA 19p13.3 Oxygen Approved Vet Approved DPYSL3 1809 upregulated Oxygen deficiency results in increased expression of DPYSL3 mRNA 5q32 Oxygen Approved Vet Approved DUSP22 56940 downregulated Oxygen deficiency results in decreased expression of DUSP22 mRNA 6p25.3 Oxygen Approved Vet Approved DUSP5 1847 upregulated Oxygen deficiency results in increased expression of DUSP5 mRNA 10q25.2 Oxygen Approved Vet Approved EBLN2 55096 upregulated Oxygen deficiency results in increased expression of EBLN2 mRNA 3p13 Oxygen Approved Vet Approved EFNA1 1942 upregulated Oxygen deficiency results in increased expression of EFNA1 mRNA 1q22 Oxygen Approved Vet Approved EIF2S2 8894 downregulated Oxygen deficiency results in decreased expression of EIF2S2 mRNA 20q11.22 Oxygen Approved Vet Approved EIF3C 8663 downregulated Oxygen deficiency results in decreased expression of EIF3C mRNA 16p11.2 Oxygen Approved Vet Approved ELF4 2000 upregulated Oxygen deficiency results in increased expression of ELF4 mRNA Xq26.1 Oxygen Approved Vet Approved ENO2 2026 upregulated Oxygen deficiency results in increased expression of ENO2 mRNA 12p13.31 Oxygen Approved Vet Approved ENOSF1 55556 upregulated Oxygen deficiency results in increased expression of ENOSF1 mRNA 18p11.32 Oxygen Approved Vet Approved ENTPD7 57089 downregulated Oxygen deficiency results in decreased expression of ENTPD7 mRNA 10q24.2 Oxygen Approved Vet Approved EP400 57634 downregulated Oxygen deficiency results in decreased expression of EP400 mRNA 12q24.33 Oxygen Approved Vet Approved EPRS 2058 downregulated Oxygen deficiency results in decreased expression of EPRS mRNA 1q41 Oxygen Approved Vet Approved EXOC7 23265 downregulated Oxygen deficiency results in decreased expression of EXOC7 mRNA 17q25.1 Oxygen Approved Vet Approved FABP3 2170 downregulated Oxygen deficiency results in decreased expression of FABP3 mRNA 1p35.2 Oxygen Approved Vet Approved FAM162A 26355 upregulated Oxygen deficiency results in increased expression of FAM162A mRNA 3q21.1 Oxygen Approved Vet Approved FAM210A 125228 upregulated Oxygen deficiency results in increased expression of FAM210A mRNA 18p11.21 Oxygen Approved Vet Approved FAM210B 116151 downregulated Oxygen deficiency results in decreased expression of FAM210B mRNA 20q13.2 Oxygen Approved Vet Approved FAM214A 56204 downregulated Oxygen deficiency results in decreased expression of FAM214A mRNA 15q21.2-q21.3 Oxygen Approved Vet Approved FAM84B 157638 downregulated Oxygen deficiency results in decreased expression of FAM84B mRNA 8q24.21 Oxygen Approved Vet Approved FAS 355 upregulated Oxygen deficiency results in increased expression of FAS mRNA 10q23.31 Oxygen Approved Vet Approved FBXO22 26263 downregulated Oxygen deficiency results in decreased expression of FBXO22 mRNA 15q24.2 Oxygen Approved Vet Approved FBXO30 84085 downregulated Oxygen deficiency results in decreased expression of FBXO30 mRNA 6q24.3 Oxygen Approved Vet Approved FECH 2235 downregulated Oxygen deficiency results in decreased expression of FECH mRNA 18q21.31 Oxygen Approved Vet Approved FOSL1 8061 upregulated Oxygen deficiency results in increased expression of FOSL1 mRNA 11q13.1 Oxygen Approved Vet Approved FOSL2 2355 upregulated Oxygen deficiency results in increased expression of FOSL2 mRNA 2p23.2 Oxygen Approved Vet Approved FREM2 341640 downregulated Oxygen deficiency results in decreased expression of FREM2 mRNA 13q13.3 Oxygen Approved Vet Approved GABARAPL1 23710 downregulated Oxygen deficiency results in decreased expression of GABARAPL1 mRNA 12p13.2 Oxygen Approved Vet Approved GADD45A 1647 upregulated Oxygen deficiency results in increased expression of GADD45A mRNA 1p31.3 Oxygen Approved Vet Approved GALNT16 57452 downregulated Oxygen deficiency results in decreased expression of GALNT16 mRNA 14q24.1 Oxygen Approved Vet Approved GARS 2617 downregulated Oxygen deficiency results in decreased expression of GARS mRNA 7p14.3 Oxygen Approved Vet Approved GBE1 2632 upregulated Oxygen deficiency results in increased expression of GBE1 mRNA 3p12.2 Oxygen Approved Vet Approved GCLC 2729 upregulated Oxygen deficiency results in increased expression of GCLC mRNA 6p12.1 Oxygen Approved Vet Approved GCLM 2730 downregulated Oxygen deficiency results in decreased expression of GCLM mRNA 1p22.1 Oxygen Approved Vet Approved GCNT3 9245 downregulated Oxygen deficiency results in decreased expression of GCNT3 mRNA 15q22.2 Oxygen Approved Vet Approved GDF15 9518 upregulated Oxygen deficiency results in increased expression of GDF15 mRNA 19p13.11 Oxygen Approved Vet Approved GOLIM4 27333 downregulated Oxygen deficiency results in decreased expression of GOLIM4 mRNA 3q26.2 Oxygen Approved Vet Approved GORASP1 64689 downregulated Oxygen deficiency results in decreased expression of GORASP1 mRNA 3p22.2 Oxygen Approved Vet Approved GOT1 2805 downregulated Oxygen deficiency results in decreased expression of GOT1 mRNA 10q24.2 Oxygen Approved Vet Approved GPAT3 84803 downregulated Oxygen deficiency results in decreased expression of GPAT3 mRNA 4q21.23 Oxygen Approved Vet Approved GPHN 10243 downregulated Oxygen deficiency results in decreased expression of GPHN mRNA 14q23.3 Oxygen Approved Vet Approved GPNMB 10457 upregulated Oxygen deficiency results in increased expression of GPNMB mRNA 7p15.3 Oxygen Approved Vet Approved GSR 2936 downregulated Oxygen deficiency results in decreased expression of GSR mRNA 8p12 Oxygen Approved Vet Approved HERC3 8916 upregulated Oxygen deficiency results in increased expression of HERC3 mRNA 4q22.1 Oxygen Approved Vet Approved HMOX1 3162 upregulated Oxygen deficiency results in increased expression of HMOX1 mRNA 22q12.3 Oxygen Approved Vet Approved HSPA1B 3304 downregulated Oxygen deficiency results in decreased expression of HSPA1B mRNA 6p21.33 Oxygen Approved Vet Approved HTATIP2 10553 downregulated Oxygen deficiency results in decreased expression of HTATIP2 mRNA 11p15.1 Oxygen Approved Vet Approved IARS 3376 downregulated Oxygen deficiency results in decreased expression of IARS mRNA 9q22.31 Oxygen Approved Vet Approved IL17RB 55540 downregulated Oxygen deficiency results in decreased expression of IL17RB mRNA 3p21.1 Oxygen Approved Vet Approved INSIG1 3638 upregulated Oxygen deficiency results in increased expression of INSIG1 mRNA 7q36.3 Oxygen Approved Vet Approved INSIG2 51141 upregulated Oxygen deficiency results in increased expression of INSIG2 mRNA 2q14.1-q14.2 Oxygen Approved Vet Approved ISCU 23479 downregulated Oxygen deficiency results in decreased expression of ISCU mRNA 12q23.3 Oxygen Approved Vet Approved ITFG2 55846 upregulated Oxygen deficiency results in increased expression of ITFG2 mRNA 12p13.33 Oxygen Approved Vet Approved ITGB1 3688 upregulated Oxygen deficiency results in increased expression of ITGB1 mRNA 10p11.22 Oxygen Approved Vet Approved KAT6B 23522 upregulated Oxygen deficiency results in increased expression of KAT6B mRNA 10q22.2 Oxygen Approved Vet Approved KDM3A 55818 upregulated Oxygen deficiency results in increased expression of KDM3A mRNA 2p11.2 Oxygen Approved Vet Approved KEAP1 9817 downregulated Oxygen deficiency results in decreased expression of KEAP1 mRNA 19p13.2 Oxygen Approved Vet Approved KRT15 3866 upregulated Oxygen deficiency results in increased expression of KRT15 mRNA 17q21.2 Oxygen Approved Vet Approved LAMA1 284217 upregulated Oxygen deficiency results in increased expression of LAMA1 mRNA 18p11.31 Oxygen Approved Vet Approved LAMA3 3909 upregulated Oxygen deficiency results in increased expression of LAMA3 mRNA 18q11.2 Oxygen Approved Vet Approved LMCD1 29995 downregulated Oxygen deficiency results in decreased expression of LMCD1 mRNA 3p25.3 Oxygen Approved Vet Approved MAFG 4097 upregulated Oxygen deficiency results in increased expression of MAFG mRNA 17q25.3 Oxygen Approved Vet Approved MAN1A2 10905 downregulated Oxygen deficiency results in decreased expression of MAN1A2 mRNA 1p12 Oxygen Approved Vet Approved MAP3K8 1326 upregulated Oxygen deficiency results in increased expression of MAP3K8 mRNA 10p11.23 Oxygen Approved Vet Approved MCOLN2 255231 downregulated Oxygen deficiency results in decreased expression of MCOLN2 mRNA 1p22.3 Oxygen Approved Vet Approved MDM2 4193 upregulated Oxygen deficiency results in increased expression of MDM2 mRNA 12q15 Oxygen Approved Vet Approved MT2A 4502 upregulated Oxygen deficiency results in increased expression of MT2A mRNA 16q13 Oxygen Approved Vet Approved MTDH 92140 upregulated Oxygen deficiency results in increased expression of MTDH mRNA 8q22.1 Oxygen Approved Vet Approved MTFP1 51537 upregulated Oxygen deficiency results in increased expression of MTFP1 mRNA 22q12.2 Oxygen Approved Vet Approved MXI1 4601 upregulated Oxygen deficiency results in increased expression of MXI1 mRNA 10q25.2 Oxygen Approved Vet Approved NAMPT 10135 downregulated Oxygen deficiency results in decreased expression of NAMPT mRNA 7q22.3 Oxygen Approved Vet Approved NAMPT 10135 upregulated Oxygen deficiency results in increased expression of NAMPT mRNA 7q22.3 Oxygen Approved Vet Approved NARS 4677 downregulated Oxygen deficiency results in decreased expression of NARS mRNA 18q21.31 Oxygen Approved Vet Approved NCAPD2 9918 downregulated Oxygen deficiency results in decreased expression of NCAPD2 mRNA 12p13.31 Oxygen Approved Vet Approved NEDD9 4739 downregulated Oxygen deficiency results in decreased expression of NEDD9 mRNA 6p24.2 Oxygen Approved Vet Approved NFE2L2 4780 downregulated Oxygen deficiency results in decreased expression of NFE2L2 mRNA 2q31.2 Oxygen Approved Vet Approved NIN 51199 downregulated Oxygen deficiency results in decreased expression of NIN mRNA 14q22.1 Oxygen Approved Vet Approved NINJ1 4814 downregulated Oxygen deficiency results in decreased expression of NINJ1 mRNA 9q22.31 Oxygen Approved Vet Approved NPY1R 4886 upregulated Oxygen deficiency results in increased expression of NPY1R mRNA 4q32.2 Oxygen Approved Vet Approved NQO1 1728 downregulated Oxygen deficiency results in decreased expression of NQO1 mRNA 16q22.1 Oxygen Approved Vet Approved NR3C1 2908 upregulated Oxygen deficiency results in increased expression of NR3C1 mRNA 5q31.3 Oxygen Approved Vet Approved NTPCR 84284 upregulated Oxygen deficiency results in increased expression of NTPCR mRNA 1q42.2 Oxygen Approved Vet Approved NUAK1 9891 upregulated Oxygen deficiency results in increased expression of NUAK1 mRNA 12q23.3 Oxygen Approved Vet Approved ORAI3 93129 upregulated Oxygen deficiency results in increased expression of ORAI3 mRNA 16p11.2 Oxygen Approved Vet Approved OXSM 54995 upregulated Oxygen deficiency results in increased expression of OXSM mRNA 3p24.2 Oxygen Approved Vet Approved P4HA1 5033 upregulated Oxygen deficiency results in increased expression of P4HA1 mRNA 10q22.1 Oxygen Approved Vet Approved PDE9A 5152 upregulated Oxygen deficiency results in increased expression of PDE9A mRNA 21q22.3 Oxygen Approved Vet Approved PDIA5 10954 upregulated Oxygen deficiency results in increased expression of PDIA5 mRNA 3q21.1 Oxygen Approved Vet Approved PDK1 5163 upregulated Oxygen deficiency results in increased expression of PDK1 mRNA 2q31.1 Oxygen Approved Vet Approved PDK4 5166 downregulated Oxygen deficiency results in decreased expression of PDK4 mRNA 7q21.3 Oxygen Approved Vet Approved PDLIM1 9124 upregulated Oxygen deficiency results in increased expression of PDLIM1 mRNA 10q23.33 Oxygen Approved Vet Approved PFKFB4 5210 upregulated Oxygen deficiency results in increased expression of PFKFB4 mRNA 3p21.31 Oxygen Approved Vet Approved PHGDH 26227 downregulated Oxygen deficiency results in decreased expression of PHGDH mRNA 1p12 Oxygen Approved Vet Approved PHLDA3 23612 upregulated Oxygen deficiency results in increased expression of PHLDA3 mRNA 1q32.1 Oxygen Approved Vet Approved PIDD1 55367 downregulated Oxygen deficiency results in decreased expression of PIDD1 mRNA 11p15.5 Oxygen Approved Vet Approved PIP5K1C 23396 downregulated Oxygen deficiency results in decreased expression of PIP5K1C mRNA 19p13.3 Oxygen Approved Vet Approved PIR 8544 downregulated Oxygen deficiency results in decreased expression of PIR mRNA Xp22.2 Oxygen Approved Vet Approved PLEC 5339 upregulated Oxygen deficiency results in increased expression of PLEC mRNA 8q24.3 Oxygen Approved Vet Approved PLK3 1263 upregulated Oxygen deficiency results in increased expression of PLK3 mRNA 1p34.1 Oxygen Approved Vet Approved PMEPA1 56937 upregulated Oxygen deficiency results in increased expression of PMEPA1 mRNA 20q13.31 Oxygen Approved Vet Approved PNPLA6 10908 downregulated Oxygen deficiency results in decreased expression of PNPLA6 mRNA 19p13.2 Oxygen Approved Vet Approved PODXL 5420 downregulated Oxygen deficiency results in decreased expression of PODXL mRNA 7q32.3 Oxygen Approved Vet Approved PPAN-P2RY11 692312 upregulated Oxygen deficiency results in increased expression of PPAN-P2RY11 mRNA 19p13.2 Oxygen Approved Vet Approved PPFIBP1 8496 downregulated Oxygen deficiency results in decreased expression of PPFIBP1 mRNA 12p11.23, 12p11.22 Oxygen Approved Vet Approved PPM1D 8493 downregulated Oxygen deficiency results in decreased expression of PPM1D mRNA 17q23.3 Oxygen Approved Vet Approved PPP1R15A 23645 upregulated Oxygen deficiency results in increased expression of PPP1R15A mRNA 19q13.2 Oxygen Approved Vet Approved PRDM1 639 upregulated Oxygen deficiency results in increased expression of PRDM1 mRNA 6q21 Oxygen Approved Vet Approved PRKAB1 5564 downregulated Oxygen deficiency results in decreased expression of PRKAB1 mRNA 12q24.23 Oxygen Approved Vet Approved PRKAB2 5565 downregulated Oxygen deficiency results in decreased expression of PRKAB2 mRNA 1q21.1 Oxygen Approved Vet Approved PRPS1 5631 downregulated Oxygen deficiency results in decreased expression of PRPS1 mRNA Xq22.3 Oxygen Approved Vet Approved PSAT1 29968 downregulated Oxygen deficiency results in decreased expression of PSAT1 mRNA 9q21.2 Oxygen Approved Vet Approved PSPC1 55269 downregulated Oxygen deficiency results in decreased expression of PSPC1 mRNA 13q12.11 Oxygen Approved Vet Approved PYCR1 5831 upregulated Oxygen deficiency results in increased expression of PYCR1 mRNA 17q25.3 Oxygen Approved Vet Approved PYGL 5836 upregulated Oxygen deficiency results in increased expression of PYGL mRNA 14q22.1 Oxygen Approved Vet Approved RAB26 25837 downregulated Oxygen deficiency results in decreased expression of RAB26 mRNA 16p13.3 Oxygen Approved Vet Approved RAB31 11031 downregulated Oxygen deficiency results in decreased expression of RAB31 mRNA 18p11.22 Oxygen Approved Vet Approved RAB33A 9363 upregulated Oxygen deficiency results in increased expression of RAB33A mRNA Xq26.1 Oxygen Approved Vet Approved RARA 5914 upregulated Oxygen deficiency results in increased expression of RARA mRNA 17q21.2 Oxygen Approved Vet Approved RIT1 6016 upregulated Oxygen deficiency results in increased expression of RIT1 mRNA 1q22 Oxygen Approved Vet Approved RLF 6018 upregulated Oxygen deficiency results in increased expression of RLF mRNA 1p34.2 Oxygen Approved Vet Approved RND1 27289 upregulated Oxygen deficiency results in increased expression of RND1 mRNA 12q13.12 Oxygen Approved Vet Approved RND3 390 upregulated Oxygen deficiency results in increased expression of RND3 mRNA 2q23.3 Oxygen Approved Vet Approved RNF121 55298 downregulated Oxygen deficiency results in decreased expression of RNF121 mRNA 11q13.4 Oxygen Approved Vet Approved RPS27L 51065 downregulated Oxygen deficiency results in decreased expression of RPS27L mRNA 15q22.2 Oxygen Approved Vet Approved RRM2B 50484 downregulated Oxygen deficiency results in decreased expression of RRM2B mRNA 8q22.3 Oxygen Approved Vet Approved RRP12 23223 downregulated Oxygen deficiency results in decreased expression of RRP12 mRNA 10q24.1 Oxygen Approved Vet Approved RSL1D1 26156 upregulated Oxygen deficiency results in increased expression of RSL1D1 mRNA 16p13.13 Oxygen Approved Vet Approved RSRC2 65117 upregulated Oxygen deficiency results in increased expression of RSRC2 mRNA 12q24.31 Oxygen Approved Vet Approved RUNX1 861 upregulated Oxygen deficiency results in increased expression of RUNX1 mRNA 21q22.12 Oxygen Approved Vet Approved RUNX2 860 downregulated Oxygen deficiency results in decreased expression of RUNX2 mRNA 6p21.1 Oxygen Approved Vet Approved RXRA 6256 downregulated Oxygen deficiency results in decreased expression of RXRA mRNA 9q34.2 Oxygen Approved Vet Approved SARM1 23098 downregulated Oxygen deficiency results in decreased expression of SARM1 mRNA 17q11.2 Oxygen Approved Vet Approved SARS 6301 upregulated Oxygen deficiency results in increased expression of SARS mRNA 1p13.3 Oxygen Approved Vet Approved SCAMP1 9522 upregulated Oxygen deficiency results in increased expression of SCAMP1 mRNA 5q14.1 Oxygen Approved Vet Approved SDF2L1 23753 downregulated Oxygen deficiency results in decreased expression of SDF2L1 mRNA 22q11.21 Oxygen Approved Vet Approved SECTM1 6398 downregulated Oxygen deficiency results in decreased expression of SECTM1 mRNA 17q25 Oxygen Approved Vet Approved SERPINB5 5268 upregulated Oxygen deficiency results in increased expression of SERPINB5 mRNA 18q21.33 Oxygen Approved Vet Approved SERTAD1 29950 downregulated Oxygen deficiency results in decreased expression of SERTAD1 mRNA 19q13.1-q13.2 Oxygen Approved Vet Approved SESN1 27244 downregulated Oxygen deficiency results in decreased expression of SESN1 mRNA 6q21 Oxygen Approved Vet Approved SETX 23064 downregulated Oxygen deficiency results in decreased expression of SETX mRNA 9q34.13 Oxygen Approved Vet Approved SFN 2810 upregulated Oxygen deficiency results in increased expression of SFN mRNA 1p36.11 Oxygen Approved Vet Approved SH3TC1 54436 downregulated Oxygen deficiency results in decreased expression of SH3TC1 mRNA 4p16.1 Oxygen Approved Vet Approved SHANK3 85358 upregulated Oxygen deficiency results in increased expression of SHANK3 mRNA 22q13.33 Oxygen Approved Vet Approved SIAH2 6478 upregulated Oxygen deficiency results in increased expression of SIAH2 mRNA 3q25.1 Oxygen Approved Vet Approved SIK1 150094 upregulated Oxygen deficiency results in increased expression of SIK1 mRNA 21q22.3 Oxygen Approved Vet Approved SIPA1L2 57568 downregulated Oxygen deficiency results in decreased expression of SIPA1L2 mRNA 1q42.2 Oxygen Approved Vet Approved SIVA1 10572 downregulated Oxygen deficiency results in decreased expression of SIVA1 mRNA 14q32.33 Oxygen Approved Vet Approved SLC12A8 84561 downregulated Oxygen deficiency results in decreased expression of SLC12A8 mRNA 3q21.2 Oxygen Approved Vet Approved SLC16A6 9120 upregulated Oxygen deficiency results in increased expression of SLC16A6 mRNA 17q24.2 Oxygen Approved Vet Approved SLC1A4 6509 downregulated Oxygen deficiency results in decreased expression of SLC1A4 mRNA 2p14 Oxygen Approved Vet Approved SLC1A5 6510 downregulated Oxygen deficiency results in decreased expression of SLC1A5 mRNA 19q13.32 Oxygen Approved Vet Approved SLC1A7 6512 upregulated Oxygen deficiency results in increased expression of SLC1A7 mRNA 1p32.3 Oxygen Approved Vet Approved SLC25A20 788 downregulated Oxygen deficiency results in decreased expression of SLC25A20 mRNA 3p21.31 Oxygen Approved Vet Approved SLC27A2 11001 downregulated Oxygen deficiency results in decreased expression of SLC27A2 mRNA 15q21.2 Oxygen Approved Vet Approved SLC2A1 6513 upregulated Oxygen deficiency results in increased expression of SLC2A1 mRNA 1p34.2 Oxygen Approved Vet Approved SLC2A11 66035 downregulated Oxygen deficiency results in decreased expression of SLC2A11 mRNA 22q11.23 Oxygen Approved Vet Approved SLC3A2 6520 upregulated Oxygen deficiency results in increased expression of SLC3A2 mRNA 11q12.3 Oxygen Approved Vet Approved SLC6A6 6533 upregulated Oxygen deficiency results in increased expression of SLC6A6 mRNA 3p25.1 Oxygen Approved Vet Approved SLC6A9 6536 downregulated Oxygen deficiency results in decreased expression of SLC6A9 mRNA 1p34.1 Oxygen Approved Vet Approved SLC7A1 6541 upregulated Oxygen deficiency results in increased expression of SLC7A1 mRNA 13q12.3 Oxygen Approved Vet Approved SLC7A11 23657 downregulated Oxygen deficiency results in decreased expression of SLC7A11 mRNA 4q28.3 Oxygen Approved Vet Approved SLC7A5 8140 upregulated Oxygen deficiency results in increased expression of SLC7A5 mRNA 16q24.2 Oxygen Approved Vet Approved SLCO2B1 11309 upregulated Oxygen deficiency results in increased expression of SLCO2B1 mRNA 11q13 Oxygen Approved Vet Approved SMAP1 60682 upregulated Oxygen deficiency results in increased expression of SMAP1 mRNA 6q13 Oxygen Approved Vet Approved SON 6651 downregulated Oxygen deficiency results in decreased expression of SON mRNA 21q22.11 Oxygen Approved Vet Approved SORL1 6653 upregulated Oxygen deficiency results in increased expression of SORL1 mRNA 11q24.1 Oxygen Approved Vet Approved SPSB1 80176 upregulated Oxygen deficiency results in increased expression of SPSB1 mRNA 1p36.22 Oxygen Approved Vet Approved SQSTM1 8878 downregulated Oxygen deficiency results in decreased expression of SQSTM1 mRNA 5q35.3 Oxygen Approved Vet Approved SRXN1 140809 downregulated Oxygen deficiency results in decreased expression of SRXN1 mRNA 20p13 Oxygen Approved Vet Approved STRBP 55342 downregulated Oxygen deficiency results in decreased expression of STRBP mRNA 9q33.1-q33.3 Oxygen Approved Vet Approved SULF2 55959 downregulated Oxygen deficiency results in decreased expression of SULF2 mRNA 20q13.12 Oxygen Approved Vet Approved TALDO1 6888 downregulated Oxygen deficiency results in decreased expression of TALDO1 mRNA 11p15.5 Oxygen Approved Vet Approved TARS 6897 downregulated Oxygen deficiency results in decreased expression of TARS mRNA 5p13.3 Oxygen Approved Vet Approved TBXAS1 6916 downregulated Oxygen deficiency results in decreased expression of TBXAS1 mRNA 7q34 Oxygen Approved Vet Approved TFE3 7030 upregulated Oxygen deficiency results in increased expression of TFE3 mRNA Xp11.23 Oxygen Approved Vet Approved TIGAR 57103 downregulated Oxygen deficiency results in decreased expression of TIGAR mRNA 12p13.32 Oxygen Approved Vet Approved TIPARP 25976 upregulated Oxygen deficiency results in increased expression of TIPARP mRNA 3q25.31 Oxygen Approved Vet Approved TMEM45A 55076 upregulated Oxygen deficiency results in increased expression of TMEM45A mRNA 3q12.2 Oxygen Approved Vet Approved TMEM45B 120224 upregulated Oxygen deficiency results in increased expression of TMEM45B mRNA 11q24.3 Oxygen Approved Vet Approved TMEM94 9772 downregulated Oxygen deficiency results in decreased expression of TMEM94 mRNA 17q25.1 Oxygen Approved Vet Approved TMTC2 160335 upregulated Oxygen deficiency results in increased expression of TMTC2 mRNA 12q21.31 Oxygen Approved Vet Approved TNFAIP8 25816 upregulated Oxygen deficiency results in increased expression of TNFAIP8 mRNA 5q23.1 Oxygen Approved Vet Approved TNFRSF10B 8795 upregulated Oxygen deficiency results in increased expression of TNFRSF10B mRNA 8p21.3 Oxygen Approved Vet Approved TNFRSF21 27242 downregulated Oxygen deficiency results in decreased expression of TNFRSF21 mRNA 6p12.3 Oxygen Approved Vet Approved TNFSF9 8744 upregulated Oxygen deficiency results in increased expression of TNFSF9 mRNA 19p13.3 Oxygen Approved Vet Approved TOP1 7150 downregulated Oxygen deficiency results in decreased expression of TOP1 mRNA 20q12 Oxygen Approved Vet Approved TP53I3 9540 upregulated Oxygen deficiency results in increased expression of TP53I3 mRNA 2p23.3 Oxygen Approved Vet Approved TP53INP1 94241 downregulated Oxygen deficiency results in decreased expression of TP53INP1 mRNA 8q22.1 Oxygen Approved Vet Approved TP53TG1 11257 downregulated Oxygen deficiency results in decreased expression of TP53TG1 mRNA 7q21.12 Oxygen Approved Vet Approved TPCN1 53373 downregulated Oxygen deficiency results in decreased expression of TPCN1 mRNA 12q24.13 Oxygen Approved Vet Approved TPD52L1 7164 upregulated Oxygen deficiency results in increased expression of TPD52L1 mRNA 6q22-q23 Oxygen Approved Vet Approved TRAFD1 10906 downregulated Oxygen deficiency results in decreased expression of TRAFD1 mRNA 12q24.13 Oxygen Approved Vet Approved TRIAP1 51499 downregulated Oxygen deficiency results in decreased expression of TRIAP1 mRNA 12q24.31 Oxygen Approved Vet Approved TRIM69 140691 upregulated Oxygen deficiency results in increased expression of TRIM69 mRNA 15q15-q21 Oxygen Approved Vet Approved TROVE2 6738 upregulated Oxygen deficiency results in increased expression of TROVE2 mRNA 1q31.2 Oxygen Approved Vet Approved TSPAN12 23554 downregulated Oxygen deficiency results in decreased expression of TSPAN12 mRNA 7q31.31 Oxygen Approved Vet Approved TXN 7295 downregulated Oxygen deficiency results in decreased expression of TXN mRNA 9q31.3 Oxygen Approved Vet Approved TXNRD1 7296 downregulated Oxygen deficiency results in decreased expression of TXNRD1 mRNA 12q23.3 Oxygen Approved Vet Approved UBE2G2 7327 downregulated Oxygen deficiency results in decreased expression of UBE2G2 mRNA 21q22.3 Oxygen Approved Vet Approved UBE2O 63893 upregulated Oxygen deficiency results in increased expression of UBE2O mRNA 17q25.1 Oxygen Approved Vet Approved USP3 9960 upregulated Oxygen deficiency results in increased expression of USP3 mRNA 15q22.3 Oxygen Approved Vet Approved VDR 7421 downregulated Oxygen deficiency results in decreased expression of VDR mRNA 12q13.11 Oxygen Approved Vet Approved VEGFB 7423 upregulated Oxygen deficiency results in increased expression of VEGFB mRNA 11q13.1 Oxygen Approved Vet Approved VIPR1 7433 downregulated Oxygen deficiency results in decreased expression of VIPR1 mRNA 3p22.1 Oxygen Approved Vet Approved VWCE 220001 downregulated Oxygen deficiency results in decreased expression of VWCE mRNA 11q12.2 Oxygen Approved Vet Approved WARS 7453 downregulated Oxygen deficiency results in decreased expression of WARS mRNA 14q32.2 Oxygen Approved Vet Approved WDR63 126820 downregulated Oxygen deficiency results in decreased expression of WDR63 mRNA 1p22.3 Oxygen Approved Vet Approved WDR7 23335 downregulated Oxygen deficiency results in decreased expression of WDR7 mRNA 18q21.31 Oxygen Approved Vet Approved WDR81 124997 downregulated Oxygen deficiency results in decreased expression of WDR81 mRNA 17p13.3 Oxygen Approved Vet Approved WWC2 80014 upregulated Oxygen deficiency results in increased expression of WWC2 mRNA 4q35.1 Oxygen Approved Vet Approved XBP1 7494 downregulated Oxygen deficiency results in decreased expression of XBP1 mRNA 22q12.1 Oxygen Approved Vet Approved XPC 7508 downregulated Oxygen deficiency results in decreased expression of XPC mRNA 3p25.1 Oxygen Approved Vet Approved YARS 8565 downregulated Oxygen deficiency results in decreased expression of YARS mRNA 1p35.1 Oxygen Approved Vet Approved YEATS2 55689 upregulated Oxygen deficiency results in increased expression of YEATS2 mRNA 3q27.1 Oxygen Approved Vet Approved YTHDC2 64848 downregulated Oxygen deficiency results in decreased expression of YTHDC2 mRNA 5q22.2 Oxygen Approved Vet Approved ZMAT3 64393 downregulated Oxygen deficiency results in decreased expression of ZMAT3 mRNA 3q26.32 Oxygen Approved Vet Approved ZNF292 23036 upregulated Oxygen deficiency results in increased expression of ZNF292 mRNA 6q14.3 Oxygen Approved Vet Approved ZNF561 93134 downregulated Oxygen deficiency results in decreased expression of ZNF561 mRNA 19p13.2 Rosiglitazone Approved Investigational ADCY1 107 downregulated rosiglitazone results in decreased expression of ADCY1 mRNA 7p12.3 Rosiglitazone Approved Investigational AGRP 181 upregulated rosiglitazone results in increased expression of AGRP mRNA 16q22.1 Rosiglitazone Approved Investigational ANGPTL4 51129 upregulated rosiglitazone results in increased expression of ANGPTL4 mRNA 19p13.2 Rosiglitazone Approved Investigational ARFGEF2 10564 upregulated rosiglitazone results in increased expression of ARFGEF2 mRNA 20q13.13 Rosiglitazone Approved Investigational ARHGEF10 9639 downregulated rosiglitazone results in decreased expression of ARHGEF10 mRNA 8p23.3 Rosiglitazone Approved Investigational ATF3 467 upregulated rosiglitazone results in increased expression of ATF3 mRNA 1q32.3 Rosiglitazone Approved Investigational CDK6 1021 downregulated rosiglitazone results in decreased expression of CDK6 mRNA 7q21.2 Rosiglitazone Approved Investigational COCH 1690 downregulated rosiglitazone results in decreased expression of COCH mRNA 14q12 Rosiglitazone Approved Investigational CTH 1491 upregulated rosiglitazone results in increased expression of CTH mRNA 1p31.1 Rosiglitazone Approved Investigational CTTN 2017 downregulated rosiglitazone results in decreased expression of CTTN mRNA 11q13.3 Rosiglitazone Approved Investigational CYP1A2 1544 upregulated rosiglitazone results in increased expression of CYP1A2 mRNA 15q24.1 Rosiglitazone Approved Investigational CYP1B1 1545 upregulated rosiglitazone results in increased expression of CYP1B1 mRNA 2p22.2 Rosiglitazone Approved Investigational DDIT3 1649 upregulated rosiglitazone results in increased expression of DDIT3 mRNA 12q13.3 Rosiglitazone Approved Investigational DUSP5 1847 upregulated rosiglitazone results in increased expression of DUSP5 mRNA 10q25.2 Rosiglitazone Approved Investigational ELK4 2005 upregulated rosiglitazone results in increased expression of ELK4 mRNA 1q32.1 Rosiglitazone Approved Investigational ENTPD7 57089 downregulated rosiglitazone results in decreased expression of ENTPD7 mRNA 10q24.2 Rosiglitazone Approved Investigational FABP4 2167 upregulated rosiglitazone results in increased expression of FABP4 mRNA 8q21.13 Rosiglitazone Approved Investigational FAM214A 56204 downregulated rosiglitazone results in decreased expression of FAM214A mRNA 15q21.2-q21.3 Rosiglitazone Approved Investigational FGR 2268 upregulated rosiglitazone results in increased expression of FGR mRNA 1p35.3 Rosiglitazone Approved Investigational FOSL1 8061 upregulated rosiglitazone results in increased expression of FOSL1 mRNA 11q13.1 Rosiglitazone Approved Investigational GABARAPL1 23710 upregulated rosiglitazone results in increased expression of GABARAPL1 mRNA 12p13.2 Rosiglitazone Approved Investigational GADD45A 1647 upregulated rosiglitazone results in increased expression of GADD45A mRNA 1p31.3 Rosiglitazone Approved Investigational GCLM 2730 upregulated rosiglitazone results in increased expression of GCLM mRNA 1p22.1 Rosiglitazone Approved Investigational GDF15 9518 upregulated rosiglitazone results in increased expression of GDF15 mRNA 19p13.11 Rosiglitazone Approved Investigational GOLIM4 27333 downregulated rosiglitazone results in decreased expression of GOLIM4 mRNA 3q26.2 Rosiglitazone Approved Investigational GPAT3 84803 upregulated rosiglitazone results in increased expression of GPAT3 mRNA 4q21.23 Rosiglitazone Approved Investigational INSIG2 51141 downregulated rosiglitazone results in decreased expression of INSIG2 mRNA 2q14.1-q14.2 Rosiglitazone Approved Investigational KEAP1 9817 upregulated rosiglitazone results in increased expression of KEAP1 mRNA 19p13.2 Rosiglitazone Approved Investigational LTN1 26046 downregulated rosiglitazone results in decreased expression of LTN1 mRNA 21q21.3 Rosiglitazone Approved Investigational MAN1A2 10905 downregulated rosiglitazone results in decreased expression of MAN1A2 mRNA 1p12 Rosiglitazone Approved Investigational MDM2 4193 upregulated rosiglitazone results in increased expression of MDM2 mRNA 12q15 Rosiglitazone Approved Investigational NEDD9 4739 downregulated rosiglitazone results in decreased expression of NEDD9 mRNA 6p24.2 Rosiglitazone Approved Investigational NREP 9315 downregulated rosiglitazone results in decreased expression of NREP mRNA 5q22.1 Rosiglitazone Approved Investigational NUAK1 9891 downregulated rosiglitazone results in decreased expression of NUAK1 mRNA 12q23.3 Rosiglitazone Approved Investigational ORAI3 93129 downregulated rosiglitazone results in decreased expression of ORAI3 mRNA 16p11.2 Rosiglitazone Approved Investigational OSGIN1 29948 upregulated rosiglitazone results in increased expression of OSGIN1 mRNA 16q23.3 Rosiglitazone Approved Investigational PDIA5 10954 downregulated rosiglitazone results in decreased expression of PDIA5 mRNA 3q21.1 Rosiglitazone Approved Investigational PDK4 5166 upregulated rosiglitazone results in increased expression of PDK4 mRNA 7q21.3 Rosiglitazone Approved Investigational PLIN2 123 upregulated rosiglitazone results in increased expression of PLIN2 mRNA 9p22.1 Rosiglitazone Approved Investigational PPM1D 8493 upregulated rosiglitazone results in increased expression of PPM1D mRNA 17q23.3 Rosiglitazone Approved Investigational PPP1R15A 23645 upregulated rosiglitazone results in increased expression of PPP1R15A mRNA 19q13.2 Rosiglitazone Approved Investigational RIT1 6016 upregulated rosiglitazone results in increased expression of RIT1 mRNA 1q22 Rosiglitazone Approved Investigational RLF 6018 upregulated rosiglitazone results in increased expression of RLF mRNA 1p34.2 Rosiglitazone Approved Investigational RPS27L 51065 downregulated rosiglitazone results in decreased expression of RPS27L mRNA 15q22.2 Rosiglitazone Approved Investigational RXRA 6256 downregulated rosiglitazone results in decreased expression of RXRA mRNA 9q34.2 Rosiglitazone Approved Investigational SCAMP1 9522 upregulated rosiglitazone results in increased expression of SCAMP1 mRNA 5q14.1 Rosiglitazone Approved Investigational SH3TC1 54436 upregulated rosiglitazone results in increased expression of SH3TC1 mRNA 4p16.1 Rosiglitazone Approved Investigational SIK1 150094 upregulated rosiglitazone results in increased expression of SIK1 mRNA 21q22.3 Rosiglitazone Approved Investigational SLC25A20 788 downregulated rosiglitazone results in decreased expression of SLC25A20 mRNA 3p21.31 Rosiglitazone Approved Investigational SLC27A2 11001 downregulated rosiglitazone results in decreased expression of SLC27A2 mRNA 15q21.2 Rosiglitazone Approved Investigational SLC2A1 6513 upregulated rosiglitazone results in increased expression of SLC2A1 mRNA 1p34.2 Rosiglitazone Approved Investigational SLC3A2 6520 upregulated rosiglitazone results in increased expression of SLC3A2 mRNA 11q12.3 Rosiglitazone Approved Investigational SLCO2B1 11309 downregulated rosiglitazone results in decreased expression of SLCO2B1 mRNA 11q13 Rosiglitazone Approved Investigational SORL1 6653 downregulated rosiglitazone results in decreased expression of SORL1 mRNA 11q24.1 Rosiglitazone Approved Investigational SRXN1 140809 upregulated rosiglitazone results in increased expression of SRXN1 mRNA 20p13 Rosiglitazone Approved Investigational SULF2 55959 downregulated rosiglitazone results in decreased expression of SULF2 mRNA 20q13.12 Rosiglitazone Approved Investigational TIPARP 25976 upregulated rosiglitazone results in increased expression of TIPARP mRNA 3q25.31 Rosiglitazone Approved Investigational TP53INP1 94241 downregulated rosiglitazone results in decreased expression of TP53INP1 mRNA 8q22.1 Rosiglitazone Approved Investigational TROVE2 6738 downregulated rosiglitazone results in decreased expression of TROVE2 mRNA 1q31.2 Rosiglitazone Approved Investigational USP3 9960 upregulated rosiglitazone results in increased expression of USP3 mRNA 15q22.3 Rosiglitazone Approved Investigational VEGFB 7423 upregulated rosiglitazone results in increased expression of VEGFB mRNA 11q13.1 Rosiglitazone Approved Investigational VWCE 220001 downregulated rosiglitazone results in decreased expression of VWCE mRNA 11q12.2 Rosiglitazone Approved Investigational WDR7 23335 downregulated rosiglitazone results in decreased expression of WDR7 mRNA 18q21.31 Rosiglitazone Approved Investigational WWC2 80014 downregulated rosiglitazone results in decreased expression of WWC2 mRNA 4q35.1 Valproic acid Approved Investigational OSGIN1 29948 upregulated Valproic Acid results in increased expression of OSGIN1 mRNA 16q23.3 Valproic acid Approved Investigational PHGDH 26227 upregulated Valproic Acid results in increased expression of PHGDH mRNA 1p12 Valproic acid Approved Investigational PLIN2 123 upregulated Valproic Acid results in increased expression of PLIN2 mRNA 9p22.1 Zoledronic acid Approved AARS 16 downregulated zoledronic acid results in decreased expression of AARS mRNA 16q22.1 Zoledronic acid Approved ABCB6 10058 downregulated zoledronic acid results in decreased expression of ABCB6 mRNA 2q35 Zoledronic acid Approved ACSL1 2180 downregulated zoledronic acid results in decreased expression of ACSL1 mRNA 4q35.1 Zoledronic acid Approved AK3 50808 downregulated zoledronic acid results in decreased expression of AK3 mRNA 9p24.1 Zoledronic acid Approved AKR1C2 1646 downregulated zoledronic acid results in decreased expression of AKR1C2 mRNA 10p15.1 Zoledronic acid Approved ALDH18A1 5832 downregulated zoledronic acid results in decreased expression of ALDH18A1 mRNA 10q24.1 Zoledronic acid Approved ALDH1A3 220 upregulated zoledronic acid results in increased expression of ALDH1A3 mRNA 15q26.3 Zoledronic acid Approved ALS2CL 259173 upregulated zoledronic acid results in increased expression of ALS2CL mRNA 3p21.31 Zoledronic acid Approved ANKRA2 57763 upregulated zoledronic acid results in increased expression of ANKRA2 mRNA 5q13.2 Zoledronic acid Approved ASNS 440 downregulated zoledronic acid results in decreased expression of ASNS mRNA 7q21.3 Zoledronic acid Approved ATXN1 6310 upregulated zoledronic acid results in increased expression of ATXN1 mRNA 6p22.3 Zoledronic acid Approved AURKB 9212 downregulated zoledronic acid results in decreased expression of AURKB mRNA 17p13.1 Zoledronic acid Approved AXL 558 downregulated zoledronic acid results in decreased expression of AXL mRNA 19q13.2 Zoledronic acid Approved BCAR3 8412 downregulated zoledronic acid results in decreased expression of BCAR3 mRNA 1p22.1 Zoledronic acid Approved BEND5 79656 downregulated zoledronic acid results in decreased expression of BEND5 mRNA 1p33 Zoledronic acid Approved BMF 90427 upregulated zoledronic acid results in increased expression of BMF mRNA 15q15.1 Zoledronic acid Approved BNIP3 664 upregulated zoledronic acid results in increased expression of BNIP3 mRNA 10q26.3 Zoledronic acid Approved BTG2 7832 downregulated zoledronic acid results in decreased expression of BTG2 mRNA 1q32.1 Zoledronic acid Approved CCNE2 9134 downregulated zoledronic acid results in decreased expression of CCNE2 mRNA 8q22.1 Zoledronic acid Approved CP 1356 upregulated zoledronic acid results in increased expression of CP mRNA 3q24-q25.1 Zoledronic acid Approved CTH 1491 downregulated zoledronic acid results in decreased expression of CTH mRNA 1p31.1 Zoledronic acid Approved CTSC 1075 upregulated zoledronic acid results in increased expression of CTSC mRNA 11q14.2 Zoledronic acid Approved CTTN 2017 downregulated zoledronic acid results in decreased expression of CTTN mRNA 11q13.3 Zoledronic acid Approved CYP1A1 1543 upregulated zoledronic acid results in increased expression of CYP1A1 mRNA 15q24.1 Zoledronic acid Approved CYP1A2 1544 upregulated zoledronic acid results in increased expression of CYP1A2 mRNA 15q24.1 Zoledronic acid Approved CYP1B1 1545 upregulated zoledronic acid results in increased expression of CYP1B1 mRNA 2p22.2 Zoledronic acid Approved DDIT4 54541 downregulated zoledronic acid results in decreased expression of DDIT4 mRNA 10q22.1 Zoledronic acid Approved DLGAP5 9787 downregulated zoledronic acid results in decreased expression of DLGAP5 mRNA 14q22.3 Zoledronic acid Approved DLX1 1745 downregulated zoledronic acid results in decreased expression of DLX1 mRNA 2q31.1 Zoledronic acid Approved DUSP5 1847 downregulated zoledronic acid results in decreased expression of DUSP5 mRNA 10q25.2 Zoledronic acid Approved EFNA1 1942 upregulated zoledronic acid results in increased expression of EFNA1 mRNA 1q22 Zoledronic acid Approved EP400 57634 downregulated zoledronic acid results in decreased expression of EP400 mRNA 12q24.33 Zoledronic acid Approved EPRS 2058 downregulated zoledronic acid results in decreased expression of EPRS mRNA 1q41 Zoledronic acid Approved FAM167A 83648 downregulated zoledronic acid results in decreased expression of FAM167A mRNA 8p23.1 Zoledronic acid Approved FAM214A 56204 upregulated zoledronic acid results in increased expression of FAM214A mRNA 15q21.2-q21.3 Zoledronic acid Approved FAM84B 157638 downregulated zoledronic acid results in decreased expression of FAM84B mRNA 8q24.21 Zoledronic acid Approved FAS 355 upregulated zoledronic acid results in increased expression of FAS mRNA 10q23.31 Zoledronic acid Approved FREM2 341640 downregulated zoledronic acid results in decreased expression of FREM2 mRNA 13q13.3 Zoledronic acid Approved FTH1 2495 upregulated zoledronic acid results in increased expression of FTH1 mRNA 11q12.3 Zoledronic acid Approved GABARAPL1 23710 downregulated zoledronic acid results in decreased expression of GABARAPL1 mRNA 12p13.2 Zoledronic acid Approved GADD45A 1647 downregulated zoledronic acid results in decreased expression of GADD45A mRNA 1p31.3 Zoledronic acid Approved GALNT16 57452 downregulated zoledronic acid results in decreased expression of GALNT16 mRNA 14q24.1 Zoledronic acid Approved GCNT3 9245 upregulated zoledronic acid results in increased expression of GCNT3 mRNA 15q22.2 Zoledronic acid Approved GDF15 9518 downregulated zoledronic acid results in decreased expression of GDF15 mRNA 19p13.11 Zoledronic acid Approved GOT1 2805 upregulated zoledronic acid results in increased expression of GOT1 mRNA 10q24.2 Zoledronic acid Approved HIST1H1C 3006 upregulated zoledronic acid results in increased expression of HIST1H1C mRNA 6p22.2 Zoledronic acid Approved HMOX1 3162 downregulated zoledronic acid results in decreased expression of HMOX1 mRNA 22q12.3 Zoledronic acid Approved HSPA5 3309 upregulated zoledronic acid results in increased expression of HSPA5 mRNA 9q33.3 Zoledronic acid Approved IL17RB 55540 downregulated zoledronic acid results in decreased expression of IL17RB mRNA 3p21.1 Zoledronic acid Approved INSIG1 3638 upregulated zoledronic acid results in increased expression of INSIG1 mRNA 7q36.3 Zoledronic acid Approved ITFG2 55846 downregulated zoledronic acid results in decreased expression of ITFG2 mRNA 12p13.33 Zoledronic acid Approved KDM3A 55818 upregulated zoledronic acid results in increased expression of KDM3A mRNA 2p11.2 Zoledronic acid Approved KRT15 3866 upregulated zoledronic acid results in increased expression of KRT15 mRNA 17q21.2 Zoledronic acid Approved LAMA1 284217 downregulated zoledronic acid results in decreased expression of LAMA1 mRNA 18p11.31 Zoledronic acid Approved LAMA3 3909 upregulated zoledronic acid results in increased expression of LAMA3 mRNA 18q11.2 Zoledronic acid Approved MAP3K8 1326 upregulated zoledronic acid results in increased expression of MAP3K8 mRNA 10p11.23 Zoledronic acid Approved ME1 4199 upregulated zoledronic acid results in increased expression of ME1 mRNA 6q14.2 Zoledronic acid Approved MT2A 4502 upregulated zoledronic acid results in increased expression of MT2A mRNA 16q13 Zoledronic acid Approved NAMPT 10135 upregulated zoledronic acid results in increased expression of NAMPT mRNA 7q22.3 Zoledronic acid Approved NARS 4677 downregulated zoledronic acid results in decreased expression of NARS mRNA 18q21.31 Zoledronic acid Approved NINJ1 4814 downregulated zoledronic acid results in decreased expression of NINJ1 mRNA 9q22.31 Zoledronic acid Approved NQO1 1728 downregulated zoledronic acid results in decreased expression of NQO1 mRNA 16q22.1 Zoledronic acid Approved NREP 9315 upregulated zoledronic acid results in increased expression of NREP mRNA 5q22.1 Zoledronic acid Approved NTPCR 84284 upregulated zoledronic acid results in increased expression of NTPCR mRNA 1q42.2 Zoledronic acid Approved OSGIN1 29948 downregulated zoledronic acid results in decreased expression of OSGIN1 mRNA 16q23.3 Zoledronic acid Approved P4HA1 5033 upregulated zoledronic acid results in increased expression of P4HA1 mRNA 10q22.1 Zoledronic acid Approved PANK1 53354 downregulated zoledronic acid results in decreased expression of PANK1 mRNA 10q23.31 Zoledronic acid Approved PDE8A 5151 upregulated zoledronic acid results in increased expression of PDE8A mRNA 15q25.3 Zoledronic acid Approved PDK4 5166 downregulated zoledronic acid results in decreased expression of PDK4 mRNA 7q21.3 Zoledronic acid Approved PFKFB4 5210 upregulated zoledronic acid results in increased expression of PFKFB4 mRNA 3p21.31 Zoledronic acid Approved PHGDH 26227 downregulated zoledronic acid results in decreased expression of PHGDH mRNA 1p12 Zoledronic acid Approved PHLDA3 23612 downregulated zoledronic acid results in decreased expression of PHLDA3 mRNA 1q32.1 Zoledronic acid Approved PIR 8544 upregulated zoledronic acid results in increased expression of PIR mRNA Xp22.2 Zoledronic acid Approved PLEC 5339 downregulated zoledronic acid results in decreased expression of PLEC mRNA 8q24.3 Zoledronic acid Approved PRC1 9055 downregulated zoledronic acid results in decreased expression of PRC1 mRNA 15q26.1 Zoledronic acid Approved PRDM1 639 upregulated zoledronic acid results in increased expression of PRDM1 mRNA 6q21 Zoledronic acid Approved PRKAB2 5565 downregulated zoledronic acid results in decreased expression of PRKAB2 mRNA 1q21.1 Zoledronic acid Approved PSAT1 29968 downregulated zoledronic acid results in decreased expression of PSAT1 mRNA 9q21.2 Zoledronic acid Approved PYGL 5836 downregulated zoledronic acid results in decreased expression of PYGL mRNA 14q22.1 Zoledronic acid Approved RAB26 25837 upregulated zoledronic acid results in increased expression of RAB26 mRNA 16p13.3 Zoledronic acid Approved RAB31 11031 upregulated zoledronic acid results in increased expression of RAB31 mRNA 18p11.22 Zoledronic acid Approved RARA 5914 downregulated zoledronic acid results in decreased expression of RARA mRNA 17q21.2 Zoledronic acid Approved RND1 27289 upregulated zoledronic acid results in increased expression of RND1 mRNA 12q13.12 Zoledronic acid Approved RUNX2 860 upregulated zoledronic acid results in increased expression of RUNX2 mRNA 6p21.1 Zoledronic acid Approved SERTAD1 29950 downregulated zoledronic acid results in decreased expression of SERTAD1 mRNA 19q13.1-q13.2 Zoledronic acid Approved SESN1 27244 downregulated zoledronic acid results in decreased expression of SESN1 mRNA 6q21 Zoledronic acid Approved SLC1A5 6510 downregulated zoledronic acid results in decreased expression of SLC1A5 mRNA 19q13.32 Zoledronic acid Approved SLC27A2 11001 downregulated zoledronic acid results in decreased expression of SLC27A2 mRNA 15q21.2 Zoledronic acid Approved SLC2A11 66035 downregulated zoledronic acid results in decreased expression of SLC2A11 mRNA 22q11.23 Zoledronic acid Approved SLC3A2 6520 downregulated zoledronic acid results in decreased expression of SLC3A2 mRNA 11q12.3 Zoledronic acid Approved SLC7A5 8140 downregulated zoledronic acid results in decreased expression of SLC7A5 mRNA 16q24.2 Zoledronic acid Approved SLCO2B1 11309 upregulated zoledronic acid results in increased expression of SLCO2B1 mRNA 11q13 Zoledronic acid Approved SRD5A3 79644 upregulated zoledronic acid results in increased expression of SRD5A3 mRNA 4q12 Zoledronic acid Approved SULF2 55959 upregulated zoledronic acid results in increased expression of SULF2 mRNA 20q13.12 Zoledronic acid Approved TIGAR 57103 downregulated zoledronic acid results in decreased expression of TIGAR mRNA 12p13.32 Zoledronic acid Approved TINAG 27283 downregulated zoledronic acid results in decreased expression of TINAG mRNA 6p12.1 Zoledronic acid Approved TIPARP 25976 upregulated zoledronic acid results in increased expression of TIPARP mRNA 3q25.31 Zoledronic acid Approved TNFAIP8 25816 upregulated zoledronic acid results in increased expression of TNFAIP8 mRNA 5q23.1 Zoledronic acid Approved TNFRSF21 27242 downregulated zoledronic acid results in decreased expression of TNFRSF21 mRNA 6p12.3 Zoledronic acid Approved TNFSF9 8744 upregulated zoledronic acid results in increased expression of TNFSF9 mRNA 19p13.3 Zoledronic acid Approved TPCN1 53373 upregulated zoledronic acid results in increased expression of TPCN1 mRNA 12q24.13 Zoledronic acid Approved TPD52L1 7164 downregulated zoledronic acid results in decreased expression of TPD52L1 mRNA 6q22-q23 Zoledronic acid Approved VIPR1 7433 upregulated zoledronic acid results in increased expression of VIPR1 mRNA 3p22.1 Zoledronic acid Approved VTCN1 79679 upregulated zoledronic acid results in increased expression of VTCN1 mRNA 1p13.1-p12 Zoledronic acid Approved YARS 8565 downregulated zoledronic acid results in decreased expression of YARS mRNA 1p35.1