Dexamethasone suppresses human interleukin-5 gene promoter.
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Mordvinov VA, Kok CC, Arthaningtyas E, Schwenger GT, Cristow A, Sanderson CJ
Dexamethasone suppresses human interleukin-5 gene promoter.
Bull Exp Biol Med. 2005 Jul;140(1):80-2.
- PubMed ID
- 16254627 [ View in PubMed]
- Abstract
Synthetic glucocorticoid dexamethasone suppressed interleukin-5 gene expression in PER-117 human T cells at the level of transcription. The conserved lymphokine element 0 in the interleukin-5 gene promoter context served as a target for dexamethasone.