Pharmacokinetics of flunixin meglumine in the cow.

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Hardee GE, Smith JA, Harris SJ

Pharmacokinetics of flunixin meglumine in the cow.

Res Vet Sci. 1985 Jul;39(1):110-2.

PubMed ID
4035085 [ View in PubMed
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Abstract

Plasma levels of flunixin were measured in heifers after a single intravenous injection (1.1 mg kg-1), using high performance liquid chromatography. Plasma concentration versus time curves were best described by a two compartment model. The distribution phase (alpha) half-life was 0.294 hours, the elimination phase (beta) half-life was 8.12 hours and the volume of distribution was 1050 ml kg-1.

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