Histidine decarboxylase

BE0000002ProteinHumansHDC

Catalyzes the biosynthesis of histamine from histidine. It is acted on by 6 drugs in DrugBank.

Gene name
HDC
UniProtKB entry
P19113Swiss-Prot
Residues / weight
662 residues · 74,140 Da
Also known as
4.1.1.22 · HDC

Resolves to

Protein
UniProtP19113UniProt nameDCHS_HUMAN
Gene
HGNCHGNC:4855NCBI Gene3067GenBank32109GeneCardsHDC
Pharmacology
KEGGhsa:3067
Structure
PDB4E1OPDB7EIWPDB7EIX
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Histidine decarboxylase, how selective are they, and which programs against it are still in active trials?

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