Cationic amino acid transporter 4

BE0000052ProteinHumansSLC7A4

Involved in the transport of the cationic amino acids (arginine, lysine and ornithine). It is acted on by 2 drugs in DrugBank.

Gene name
SLC7A4
UniProtKB entry
O43246Swiss-Prot
Cellular location
Membrane
Residues / weight
635 residues · 68,267 Da
Also known as
CAT-4 · CAT4 · Solute carrier family 7 member 4

Resolves to

Protein
UniProtO43246UniProt nameCTR4_HUMAN
Gene
HGNCHGNC:11062NCBI Gene6545GenBank4378940GeneCardsSLC7A4
Pharmacology
KEGGhsa:6545
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cationic amino acid transporter 4, how selective are they, and which programs against it are still in active trials?

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