Malate dehydrogenase

BE0000056ProteinEscherichia coli (strain K12)mdh

Catalyzes the reversible oxidation of malate to oxaloacetate. It is acted on by 2 drugs in DrugBank.

Gene name
mdh
UniProtKB entry
P61889Swiss-Prot
Residues / weight
312 residues · 32,337 Da
Also known as
1.1.1.37

Resolves to

Protein
UniProtP61889UniProt nameMDH_ECOLI
Gene
NCBI Gene947854GenBank41989
Pharmacology
KEGGecj:JW3205
Structure
PDB1CMEPDB1EMDPDB1IB6
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Malate dehydrogenase, how selective are they, and which programs against it are still in active trials?

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